Published in Differentiation on February 05, 2007
Anaplastic lymphoma kinase: signalling in development and disease. Biochem J (2009) 3.05
Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology. Nat Rev Cancer (2013) 2.17
Anterograde Jelly belly ligand to Alk receptor signaling at developing synapses is regulated by Mind the gap. Development (2010) 0.96
Glycosylated synaptomatrix regulation of trans-synaptic signaling. Dev Neurobiol (2012) 0.95
Receptor tyrosine kinases in Drosophila development. Cold Spring Harb Perspect Biol (2013) 0.83
Org-1 is required for the diversification of circular visceral muscle founder cells and normal midgut morphogenesis. Dev Biol (2013) 0.78
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Nature (2011) 4.14
Anaplastic lymphoma kinase: signalling in development and disease. Biochem J (2009) 3.05
Tomographic molecular imaging and 3D quantification within adult mouse organs. Nat Methods (2006) 2.23
Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology. Nat Rev Cancer (2013) 2.17
High-resolution three-dimensional imaging of islet-infiltrate interactions based on optical projection tomography assessments of the intact adult mouse pancreas. J Biomed Opt (2008) 1.88
Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion. Nature (2003) 1.59
Anterograde Jelly belly and Alk receptor tyrosine kinase signaling mediates retinal axon targeting in Drosophila. Cell (2007) 1.46
Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis. EMBO J (2007) 1.38
WASP and SCAR have distinct roles in activating the Arp2/3 complex during myoblast fusion. J Cell Sci (2008) 1.35
A crucial role for the Anaplastic lymphoma kinase receptor tyrosine kinase in gut development in Drosophila melanogaster. EMBO Rep (2003) 1.24
Characterization of the expression of the ALK receptor tyrosine kinase in mice. Gene Expr Patterns (2006) 1.24
Exoenzyme S shows selective ADP-ribosylation and GTPase-activating protein (GAP) activities towards small GTPases in vivo. Biochem J (2002) 1.17
Focal adhesion kinase is not required for integrin function or viability in Drosophila. Development (2004) 1.14
Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma. Dis Model Mech (2012) 1.14
Activating ALK mutations found in neuroblastoma are inhibited by Crizotinib and NVP-TAE684. Biochem J (2011) 1.11
Appearance of the novel activating F1174S ALK mutation in neuroblastoma correlates with aggressive tumor progression and unresponsiveness to therapy. Cancer Res (2010) 1.07
Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster. Curr Biol (2010) 1.02
Activation of the MAP kinase pathway by c-Kit is PI-3 kinase dependent in hematopoietic progenitor/stem cell lines. Blood (2004) 1.02
Crizotinib--latest champion in the cancer wars? N Engl J Med (2010) 1.01
CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice. EMBO J (2010) 0.96
Fak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growth. Neural Dev (2008) 0.95
The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning. PLoS Genet (2011) 0.92
The neuroblastoma ALK(I1250T) mutation is a kinase-dead RTK in vitro and in vivo. Transl Oncol (2011) 0.91
The ligand Jelly Belly (Jeb) activates the Drosophila Alk RTK to drive PC12 cell differentiation, but is unable to activate the mouse ALK RTK. J Exp Zool B Mol Dev Evol (2007) 0.91
Myoblast determination in the somatic and visceral mesoderm depends on Notch signalling as well as on milliways(mili(Alk)) as receptor for Jeb signalling. Development (2004) 0.88
Miple1 and miple2 encode a family of MK/PTN homologues in Drosophila melanogaster. Dev Genes Evol (2005) 0.88
Fusion of circular and longitudinal muscles in Drosophila is independent of the endoderm but further visceral muscle differentiation requires a close contact between mesoderm and endoderm. Mech Dev (2009) 0.86
ALK and NSCLC: Targeted therapy with ALK inhibitors. F1000 Med Rep (2011) 0.85
Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation. EMBO J (2013) 0.85
Mutation of Drosophila focal adhesion kinase induces bang-sensitive behavior and disrupts glial function, axonal conduction and synaptic transmission. Eur J Neurosci (2008) 0.83
The bHLH transcription factor Hand is regulated by Alk in the Drosophila embryonic gut. Biochem Biophys Res Commun (2006) 0.83
Exoenzyme S of Pseudomonas aeruginosa is not able to induce apoptosis when cells express activated proteins, such as Ras or protein kinase B/Akt. Cell Microbiol (2006) 0.83
Jeb/Alk signalling regulates the Lame duck GLI family transcription factor in the Drosophila visceral mesoderm. Development (2013) 0.82
Delineation of exoenzyme S residues that mediate the interaction with 14-3-3 and its biological activity. FEBS J (2006) 0.82
Pattern of tissue invasion by Propionibacterium acnes in acne vulgaris. J Dermatol Sci (2012) 0.81
Intragenic anaplastic lymphoma kinase (ALK) rearrangements: translocations as a novel mechanism of ALK activation in neuroblastoma tumors. Genes Chromosomes Cancer (2014) 0.80
Electrostatic interactions play a minor role in the binding of ExoS to 14-3-3 proteins. Biochem J (2010) 0.78
Characterisation of the role of Vrp1 in cell fusion during the development of visceral muscle of Drosophila melanogaster. BMC Dev Biol (2010) 0.76
The Rap1 guanine nucleotide exchange factor C3G is required for preservation of larval muscle integrity in Drosophila melanogaster. PLoS One (2010) 0.75
Simultaneous visualization of Propionibacterium acnes and Propionibacterium granulosum with immunofluorescence and fluorescence in situ hybridization. Anaerobe (2013) 0.75
Microbiology of folliculitis: a histological study of 39 cases. APMIS (2013) 0.75
Spatial distribution of bacterial-fungal communities in facial skin. J Dermatol Sci (2012) 0.75
Haematopoietic progenitor cells utilise conventional PKC to suppress PKB/Akt activity in response to c-Kit stimulation. Br J Haematol (2006) 0.75