Published in Development on October 01, 2010
Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology. Nat Rev Cancer (2013) 2.17
An evolutionary conserved role for anaplastic lymphoma kinase in behavioral responses to ethanol. PLoS One (2011) 1.10
A targeted glycan-related gene screen reveals heparan sulfate proteoglycan sulfation regulates WNT and BMP trans-synaptic signaling. PLoS Genet (2012) 1.00
Extracellular matrix and its receptors in Drosophila neural development. Dev Neurobiol (2011) 0.98
Glycosylated synaptomatrix regulation of trans-synaptic signaling. Dev Neurobiol (2012) 0.95
The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning. PLoS Genet (2011) 0.92
Transmission, Development, and Plasticity of Synapses. Genetics (2015) 0.89
Neuron-type specific functions of DNT1, DNT2 and Spz at the Drosophila neuromuscular junction. PLoS One (2013) 0.87
Overelaborated synaptic architecture and reduced synaptomatrix glycosylation in a Drosophila classic galactosemia disease model. Dis Model Mech (2014) 0.85
Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila. Dis Model Mech (2013) 0.84
Jelly Belly trans-synaptic signaling to anaplastic lymphoma kinase regulates neurotransmission strength and synapse architecture. Dev Neurobiol (2012) 0.84
Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways. Gene Ther (2014) 0.83
Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency. PLoS Genet (2013) 0.83
Structure-function analysis of endogenous lectin mind-the-gap in synaptogenesis. Dev Neurobiol (2012) 0.83
Receptor tyrosine kinases in Drosophila development. Cold Spring Harb Perspect Biol (2013) 0.83
N-glycosylation requirements in neuromuscular synaptogenesis. Development (2013) 0.82
The cell polarity scaffold Lethal Giant Larvae regulates synapse morphology and function. J Cell Sci (2013) 0.81
Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs. Cell Mol Life Sci (2016) 0.77
The Drosophila midkine/pleiotrophin homologues Miple1 and Miple2 affect adult lifespan but are dispensable for alk signaling during embryonic gut formation. PLoS One (2014) 0.77
Anaplastic Lymphoma Kinase Acts in the Drosophila Mushroom Body to Negatively Regulate Sleep. PLoS Genet (2015) 0.76
Pleiotrophin as a central nervous system neuromodulator, evidences from the hippocampus. Front Cell Neurosci (2015) 0.75
ALK: a tyrosine kinase target for cancer therapy. Cold Spring Harb Mol Case Stud (2017) 0.75
A Drosophila screen identifies neurofibromatosis-1 genetic modifiers involved in systemic and synaptic growth. Rare Dis (2014) 0.75
wishful thinking encodes a BMP type II receptor that regulates synaptic growth in Drosophila. Neuron (2002) 3.79
The Drosophila Wnt, wingless, provides an essential signal for pre- and postsynaptic differentiation. Cell (2002) 3.17
Anaplastic lymphoma kinase: signalling in development and disease. Biochem J (2009) 3.05
Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless. Cell (2009) 2.91
The BMP homolog Gbb provides a retrograde signal that regulates synaptic growth at the Drosophila neuromuscular junction. Neuron (2003) 2.86
To build a synapse: signaling pathways in neuromuscular junction assembly. Development (2010) 2.65
Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2. Science (2005) 2.53
Rapid activity-dependent modifications in synaptic structure and function require bidirectional Wnt signaling. Neuron (2008) 2.23
Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lost. Curr Opin Neurobiol (2005) 2.13
Development of the embryonic neuromuscular synapse of Drosophila melanogaster. J Neurosci (1993) 2.03
Highwire regulates presynaptic BMP signaling essential for synaptic growth. Neuron (2004) 1.91
Extracellular matrix molecules and synaptic plasticity. Nat Rev Neurosci (2003) 1.85
Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers. Nature (2003) 1.69
Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion. Nature (2003) 1.59
Retrograde control of synaptic transmission by postsynaptic CaMKII at the Drosophila neuromuscular junction. Neuron (2003) 1.53
Heparan sulfate proteoglycans and the emergence of neuronal connectivity. Curr Opin Neurobiol (2006) 1.47
Anterograde Jelly belly and Alk receptor tyrosine kinase signaling mediates retinal axon targeting in Drosophila. Cell (2007) 1.46
Presynaptic local signaling by a canonical wingless pathway regulates development of the Drosophila neuromuscular junction. J Neurosci (2008) 1.45
Wnts and TGF beta in synaptogenesis: old friends signalling at new places. Nat Rev Neurosci (2003) 1.37
An essential Drosophila glutamate receptor subunit that functions in both central neuropil and neuromuscular junction. J Neurosci (2005) 1.36
Leonardo, a Drosophila 14-3-3 protein involved in learning, regulates presynaptic function. Neuron (1997) 1.27
A crucial role for the Anaplastic lymphoma kinase receptor tyrosine kinase in gut development in Drosophila melanogaster. EMBO Rep (2003) 1.24
Ceramidase regulates synaptic vesicle exocytosis and trafficking. J Neurosci (2004) 1.24
Characterization of the expression of the ALK receptor tyrosine kinase in mice. Gene Expr Patterns (2006) 1.24
Drosophila alpha- and beta-spectrin mutations disrupt presynaptic neurotransmitter release. J Neurosci (2001) 1.24
The extracellular matrix and synapses. Cell Tissue Res (2006) 1.14
Postsynaptic expression of tetanus toxin light chain blocks synaptogenesis in Drosophila. Curr Biol (1999) 1.14
Retrograde signalling at the synapse: a role for Wnt proteins. Biochem Soc Trans (2005) 1.12
Identification and characterization of DAlk: a novel Drosophila melanogaster RTK which drives ERK activation in vivo. Genes Cells (2001) 1.08
Presynaptic establishment of the synaptic cleft extracellular matrix is required for post-synaptic differentiation. Genes Dev (2007) 1.07
Postsynaptic protein kinase A reduces neuronal excitability in response to increased synaptic excitation in the Drosophila CNS. J Neurosci (2003) 1.02
Jelly belly: a Drosophila LDL receptor repeat-containing signal required for mesoderm migration and differentiation. Cell (2001) 1.00
Harvesting and preparing Drosophila embryos for electrophysiological recording and other procedures. J Vis Exp (2009) 0.97
C. elegans anaplastic lymphoma kinase ortholog SCD-2 controls dauer formation by modulating TGF-beta signaling. Curr Biol (2008) 0.96
Derailed regulates development of the Drosophila neuromuscular junction. Dev Neurobiol (2008) 0.94
Synaptic strengthening mediated by bone morphogenetic protein-dependent retrograde signaling in the Drosophila CNS. J Neurosci (2004) 0.92
Regulation of synaptic connectivity: levels of Fasciclin II influence synaptic growth in the Drosophila CNS. J Neurosci (2002) 0.91
Myoblast determination in the somatic and visceral mesoderm depends on Notch signalling as well as on milliways(mili(Alk)) as receptor for Jeb signalling. Development (2004) 0.88
Synaptogenesis: Wnt and TGF-beta take centre stage. Curr Biol (2003) 0.87
Mutation in slowmo causes defects in Drosophila larval locomotor behaviour. Invert Neurosci (2003) 0.86
Presynaptic secretion of mind-the-gap organizes the synaptic extracellular matrix-integrin interface and postsynaptic environments. Dev Dyn (2009) 0.86
The synaptomatrix: a solid though dynamic contact disconnecting transmissions from exocytotic events. Neurochem Int (2010) 0.85
The bHLH transcription factor Hand is regulated by Alk in the Drosophila embryonic gut. Biochem Biophys Res Commun (2006) 0.83
Drosophila Anaplastic Lymphoma Kinase regulates Dpp signalling in the developing embryonic gut. Differentiation (2007) 0.81
The role of ECM molecules in activity-dependent synaptic development and plasticity. Birth Defects Res C Embryo Today (2004) 0.81
The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function. Curr Biol (2004) 2.06
Living synaptic vesicle marker: synaptotagmin-GFP. Genesis (2002) 1.99
The ubiquitin proteasome system acutely regulates presynaptic protein turnover and synaptic efficacy. Curr Biol (2003) 1.91
Spartin regulates synaptic growth and neuronal survival by inhibiting BMP-mediated microtubule stabilization. Neuron (2013) 1.83
CNS-derived glia ensheath peripheral nerves and mediate motor root development. Nat Neurosci (2008) 1.73
Motor deficit in a Drosophila model of mucolipidosis type IV due to defective clearance of apoptotic cells. Cell (2008) 1.69
The Drosophila fragile X gene negatively regulates neuronal elaboration and synaptic differentiation. Curr Biol (2004) 1.60
Wrestling with pleiotropy: genomic and topological analysis of the yeast gene expression network. Bioessays (2002) 1.58
Drosophila fragile X mental retardation protein developmentally regulates activity-dependent axon pruning. Development (2008) 1.52
An essential Drosophila glutamate receptor subunit that functions in both central neuropil and neuromuscular junction. J Neurosci (2005) 1.36
Electrophysiological analysis of synaptic transmission in central neurons of Drosophila larvae. J Neurophysiol (2002) 1.33
Developmental regulation of glutamate receptor field size by nonvesicular glutamate release. Nat Neurosci (2002) 1.26
Ceramidase regulates synaptic vesicle exocytosis and trafficking. J Neurosci (2004) 1.24
Lipid regulation of the synaptic vesicle cycle. Nat Rev Neurosci (2005) 1.22
Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structure. Development (2008) 1.21
Roles of ubiquitination at the synapse. Biochim Biophys Acta (2008) 1.19
Genetic controls balancing excitatory and inhibitory synaptogenesis in neurodevelopmental disorder models. Front Synaptic Neurosci (2010) 1.18
Mechanistic relationships between Drosophila fragile X mental retardation protein and metabotropic glutamate receptor A signaling. Mol Cell Neurosci (2008) 1.15
Presynaptic establishment of the synaptic cleft extracellular matrix is required for post-synaptic differentiation. Genes Dev (2007) 1.07
Synaptic Drosophila UNC-13 is regulated by antagonistic G-protein pathways via a proteasome-dependent degradation mechanism. J Neurobiol (2003) 1.05
Neuronal loss of Drosophila NPC1a causes cholesterol aggregation and age-progressive neurodegeneration. J Neurosci (2008) 1.04
Rolling blackout, a newly identified PIP2-DAG pathway lipase required for Drosophila phototransduction. Nat Neurosci (2004) 1.04
Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P. Dis Model Mech (2010) 1.02
Cellular bases of activity-dependent paralysis in Drosophila stress-sensitive mutants. J Neurobiol (2004) 1.02
Protein expression profiling of the drosophila fragile X mutant brain reveals up-regulation of monoamine synthesis. Mol Cell Proteomics (2005) 1.02
Cellular bases of behavioral plasticity: establishing and modifying synaptic circuits in the Drosophila genetic system. J Neurobiol (2003) 1.01
The Drosophila metabotropic glutamate receptor DmGluRA regulates activity-dependent synaptic facilitation and fine synaptic morphology. J Neurosci (2004) 1.00
Rolling blackout is required for synaptic vesicle exocytosis. J Neurosci (2006) 1.00
The Cdc42-selective GAP rich regulates postsynaptic development and retrograde BMP transsynaptic signaling. J Cell Biol (2010) 1.00
A targeted glycan-related gene screen reveals heparan sulfate proteoglycan sulfation regulates WNT and BMP trans-synaptic signaling. PLoS Genet (2012) 1.00
The fragile X mental retardation protein in circadian rhythmicity and memory consolidation. Mol Neurobiol (2009) 0.99
The Drosophila fragile X-related gene regulates axoneme differentiation during spermatogenesis. Dev Biol (2004) 0.98
Harvesting and preparing Drosophila embryos for electrophysiological recording and other procedures. J Vis Exp (2009) 0.97
Presynaptic calcium channel localization and calcium-dependent synaptic vesicle exocytosis regulated by the Fuseless protein. J Neurosci (2008) 0.97
Integrins regulate DLG/FAS2 via a CaM kinase II-dependent pathway to mediate synapse elaboration and stabilization during postembryonic development. Development (2002) 0.97
Fathoming fragile X in fruit flies. Trends Genet (2005) 0.96
The ubiquitin-proteasome system postsynaptically regulates glutamatergic synaptic function. Mol Cell Neurosci (2007) 0.96
In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation. Hum Mol Genet (2011) 0.96
Glycosylated synaptomatrix regulation of trans-synaptic signaling. Dev Neurobiol (2012) 0.95
Matrix metalloproteinases and minocycline: therapeutic avenues for fragile X syndrome. Neural Plast (2012) 0.94
Drosophila sec10 is required for hormone secretion but not general exocytosis or neurotransmission. Traffic (2002) 0.94
Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase. Dis Model Mech (2011) 0.94
Proteasome function is required to maintain muscle cellular architecture. Biol Cell (2007) 0.94
Mutation and activation of Galpha s similarly alters pre- and postsynaptic mechanisms modulating neurotransmission. J Neurophysiol (2003) 0.93
Activity-dependent modulation of neural circuit synaptic connectivity. Front Mol Neurosci (2009) 0.93
Mutational analysis establishes a critical role for the N terminus of fragile X mental retardation protein FMRP. J Neurosci (2008) 0.93
miR-153 regulates SNAP-25, synaptic transmission, and neuronal development. PLoS One (2013) 0.92
The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy. J Cell Sci (2010) 0.92
Metabotropic glutamate receptor-mediated use-dependent down-regulation of synaptic excitability involves the fragile X mental retardation protein. J Neurophysiol (2008) 0.90
Rolling blackout is required for bulk endocytosis in non-neuronal cells and neuronal synapses. J Cell Sci (2008) 0.89
The fragile X mental retardation protein developmentally regulates the strength and fidelity of calcium signaling in Drosophila mushroom body neurons. Neurobiol Dis (2010) 0.89
Temporal requirements of the fragile x mental retardation protein in modulating circadian clock circuit synaptic architecture. Front Neural Circuits (2009) 0.89
Presynaptic secretion of mind-the-gap organizes the synaptic extracellular matrix-integrin interface and postsynaptic environments. Dev Dyn (2009) 0.86
Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila. Dis Model Mech (2013) 0.84
Drosophila modeling of heritable neurodevelopmental disorders. Curr Opin Neurobiol (2011) 0.84
Jelly Belly trans-synaptic signaling to anaplastic lymphoma kinase regulates neurotransmission strength and synapse architecture. Dev Neurobiol (2012) 0.84
Fragile X mental retardation protein is required for programmed cell death and clearance of developmentally-transient peptidergic neurons. Dev Biol (2011) 0.83
Molecular and genetic analysis of the Drosophila model of fragile X syndrome. Results Probl Cell Differ (2012) 0.83
Structure-function analysis of endogenous lectin mind-the-gap in synaptogenesis. Dev Neurobiol (2012) 0.83
N-glycosylation requirements in neuromuscular synaptogenesis. Development (2013) 0.82
In vivo assay of presynaptic microtubule cytoskeleton dynamics in Drosophila. J Neurosci Methods (2007) 0.82
The cell polarity scaffold Lethal Giant Larvae regulates synapse morphology and function. J Cell Sci (2013) 0.81
Two peptide transmitters co-packaged in a single neurosecretory vesicle. Peptides (2008) 0.81
Techniques to dissect cellular and subcellular function in the Drosophila nervous system. Methods Cell Biol (2003) 0.80
Electrophysiological recording in the Drosophila embryo. J Vis Exp (2009) 0.80
Response: meaningless minis? Trends Neurosci (2002) 0.79
Drosophila rolling blackout displays lipase domain-dependent and -independent endocytic functions downstream of dynamin. Traffic (2010) 0.77
Expression and function of scalloped during Drosophila development. Dev Dyn (2013) 0.77