Published in Science on February 06, 2004
Bushmeat hunting, deforestation, and prediction of zoonoses emergence. Emerg Infect Dis (2005) 2.93
Demographic structure and pathogen dynamics on the network of livestock movements in Great Britain. Proc Biol Sci (2006) 2.40
Networks and the epidemiology of infectious disease. Interdiscip Perspect Infect Dis (2011) 2.00
Adaptation and the evolution of parasite virulence in a connected world. Nature (2009) 1.53
Correlates of viral richness in bats (order Chiroptera). Ecohealth (2010) 1.39
Uncovering epidemiological dynamics in heterogeneous host populations using phylogenetic methods. Philos Trans R Soc Lond B Biol Sci (2013) 1.31
Emergent trade-offs and selection for outbreak frequency in spatial epidemics. Proc Natl Acad Sci U S A (2004) 1.24
Ecology of zoonotic infectious diseases in bats: current knowledge and future directions. Zoonoses Public Health (2012) 1.24
Evolutionary history and attenuation of myxoma virus on two continents. PLoS Pathog (2012) 1.22
Selection in spatial stochastic models of cancer: migration as a key modulator of fitness. Biol Direct (2010) 1.17
Presence/absence polymorphism for alternative pathogenicity islands in Pseudomonas viridiflava, a pathogen of Arabidopsis. Proc Natl Acad Sci U S A (2006) 1.16
Parallel patterns of increased virulence in a recently emerged wildlife pathogen. PLoS Biol (2013) 1.13
Are parasites ''prudent'' in space? Ecol Lett (2010) 1.13
Evolution and emergence of infectious diseases in theoretical and real-world networks. Nat Commun (2015) 1.03
Host-parasite interactions and the evolution of gene expression. PLoS Biol (2005) 1.01
How populations persist when asexuality requires sex: the spatial dynamics of coping with sperm parasites. Proc Biol Sci (2008) 1.00
Spatial invasion by a mutant pathogen. J Theor Biol (2005) 0.98
Evolution of acute infections and the invasion-persistence trade-off. Am Nat (2009) 0.98
Do pathogens become more virulent as they spread? Evidence from the amphibian declines in Central America. Proc Biol Sci (2013) 0.95
Pathogens, social networks, and the paradox of transmission scaling. Interdiscip Perspect Infect Dis (2011) 0.94
Lyssaviruses and bats: emergence and zoonotic threat. Viruses (2014) 0.92
The evolution of covert, silent infection as a parasite strategy. Proc Biol Sci (2009) 0.89
Dances with worms: the ecological and evolutionary impacts of deworming on coinfecting pathogens. Parasitology (2013) 0.89
The adaptive evolution of virulence: a review of theoretical predictions and empirical tests. Parasitology (2015) 0.88
Evolution of pathogen virulence across space during an epidemic. Am Nat (2015) 0.88
Oligomorphic dynamics for analyzing the quantitative genetics of adaptive speciation. J Math Biol (2010) 0.83
The implications of immunopathology for parasite evolution. Proc Biol Sci (2012) 0.83
The impact of spatial scale and habitat configuration on patterns of trait variation and local adaptation in a wild plant parasite. Evolution (2013) 0.82
Two component systems: physiological effect of a third component. PLoS One (2012) 0.82
Genomic Correlates of Virulence Attenuation in the Deadly Amphibian Chytrid Fungus, Batrachochytrium dendrobatidis. G3 (Bethesda) (2015) 0.82
Stochastic extinction and the selection of the transmission mode in microparasites. J R Soc Interface (2008) 0.79
Spatial pattern switching enables cyclic evolution in spatial epidemics. PLoS Comput Biol (2010) 0.78
Evolution of acuteness in pathogen metapopulations: conflicts between "classical" and invasion-persistence trade-offs. Theor Ecol (2014) 0.77
Resolving the Origin of Rabbit Hemorrhagic Disease Virus: Insights from an Investigation of the Viral Stocks Released in Australia. J Virol (2015) 0.77
Cysticercus fasciolaris infection induced oxidative stress and apoptosis in rat liver: a strategy for host-parasite cross talk. Parasitol Res (2016) 0.76
The impact of spatial structure on viral genomic diversity generated during adaptation to thermal stress. PLoS One (2014) 0.76
Proteomics progresses in microbial physiology and clinical antimicrobial therapy. Eur J Clin Microbiol Infect Dis (2016) 0.75
Quality and quantity: transitions in antimicrobial gland use for parasite defense. Ecol Evol (2015) 0.75
Host social organization and mating system shape parasite transmission opportunities in three European bat species. Parasitol Res (2016) 0.75
Host population structure impedes reversion to drug sensitivity after discontinuation of treatment. PLoS Comput Biol (2017) 0.75
The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. EMBO J (1999) 3.77
Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo. J Bone Miner Res (1995) 3.23
Parathyroid hormone-related protein purified from a human lung cancer cell line. Proc Natl Acad Sci U S A (1987) 3.06
Negative regulation of cytokine signaling pathways. Annu Rev Immunol (2000) 2.98
Spred is a Sprouty-related suppressor of Ras signalling. Nature (2001) 2.87
Structure and control of phosphofructokinase from Bacillus stearothermophilus. Nature (1979) 2.70
Successful en-bloc resection of large superficial tumors in the stomach and colon using sodium hyaluronate and small-caliber-tip transparent hood. Endoscopy (2003) 2.67
Cloning and characterization of novel CIS family genes. Biochem Biophys Res Commun (1997) 2.51
'Small worlds' and the evolution of virulence: infection occurs locally and at a distance. Proc Biol Sci (1999) 2.31
SOCS3 is essential in the regulation of fetal liver erythropoiesis. Cell (1999) 2.19
Phylogenetic analysis of nucleoproteins suggests that human influenza A viruses emerged from a 19th-century avian ancestor. Mol Biol Evol (1990) 2.07
Pathogen invasion and host extinction in lattice structured populations. J Math Biol (1994) 2.05
Phosphofructokinase: structure and control. Philos Trans R Soc Lond B Biol Sci (1981) 2.01
Continuous ambulatory radionuclide monitoring of left ventricular function: effect of body position during ergometer exercise. J Nucl Med (1997) 1.99
Genomic structure of the large RNA segment of infectious bursal disease virus. Nucleic Acids Res (1986) 1.96
Evolutionarily stable mutation rate in a periodically changing environment. Genetics (1989) 1.96
EUS in cirrhotic patients with and without prior variceal hemorrhage in comparison with noncirrhotic control subjects. Gastrointest Endosc (2000) 1.94
Deletion mapping and expression in Escherichia coli of the large genomic segment of a birnavirus. Virology (1987) 1.68
A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons. Blood (1998) 1.68
Osteolytic bone metastasis in breast cancer. Breast Cancer Res Treat (1994) 1.61
Phosphofructokinase: complete amino-acid sequence of the enzyme from Bacillus stearothermophilus. Eur J Biochem (1980) 1.59
The evolution of parasite virulence and transmission rate in a spatially structured population. J Theor Biol (2000) 1.53
Preventive effects of cyclosporin on diabetes in NOD mice. Diabetologia (1986) 1.52
A long-term follow-up study of diabetic patients in Osaka, Japan: mortality and causes of death. Tohoku J Exp Med (1983) 1.50
Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2. J Clin Invest (1997) 1.49
Parasites, disease and the structure of ecological communities. Trends Ecol Evol (1986) 1.47
Neonatal hyperbilirubinemia and mutation of the bilirubin uridine diphosphate-glucuronosyltransferase gene: a common missense mutation among Japanese, Koreans and Chinese. Biochem Mol Biol Int (1998) 1.44
Persistence of tick-borne virus in the presence of multiple host species: tick reservoirs and parasite mediated competition. J Theor Biol (1999) 1.41
APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis. Oncogene (1999) 1.41
Chemotactic adaptation is altered by changes in the carboxy-terminal sequence conserved among the major methyl-accepting chemoreceptors. J Bacteriol (1998) 1.39
The looped square knot: a useful suture method. Plast Reconstr Surg (1981) 1.39
Carcinoma of the gallbladder associated with anomalous junction of the pancreaticobiliary duct in adults. J Am Coll Surg (1999) 1.38
Faecal egg counts provide a reliable measure of Trichostrongylus tenuis intensities in free-living red grouse Lagopus lagopus scoticus. J Helminthol (2004) 1.36
Immunohistochemical localization of neurofilament protein in neuronal degenerations. Acta Neuropathol (1984) 1.36
A prospective cohort study on National Health Insurance beneficiaries in Ohsaki, Miyagi Prefecture, Japan: study design, profiles of the subjects and medical cost during the first year. J Epidemiol (1998) 1.33
Dimeric and trimeric antibodies: high avidity scFvs for cancer targeting. Biomol Eng (2001) 1.32
Establishment of high and low metastasis cell lines derived from a human tongue squamous cell carcinoma. Invasion Metastasis (2000) 1.32
Structure of the 5' flanking region of the gene encoding human parathyroid-hormone-related protein (PTHrP). Gene (1989) 1.31
E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model. Cancer Res (1996) 1.30
Host-parasite arms race in mutation modifications: indefinite escalation despite a heavy load? J Theor Biol (1996) 1.29
Design and application of diabodies, triabodies and tetrabodies for cancer targeting. J Immunol Methods (2001) 1.28
Isolation of Campylobacter jejuni from milk during an outbreak of campylobacteriosis. J Infect Dis (1984) 1.24
Familial gastric cancer: clinicopathological characteristics, RER phenotype and germline p53 and E-cadherin mutations. Carcinogenesis (1999) 1.23
JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling. Blood (2001) 1.22
CIS associates with the interleukin-2 receptor beta chain and inhibits interleukin-2-dependent signaling. J Biol Chem (1999) 1.21
The effect of aggressiveness on the population dynamics of a territorial bird. Nature (2003) 1.20
Peak shift and epidemiology in a seasonal host-nematode system. Proc Biol Sci (2005) 1.17
APS, an adaptor protein containing Pleckstrin homology (PH) and Src homology-2 (SH2) domains inhibits the JAK-STAT pathway in collaboration with c-Cbl. Leukemia (1999) 1.16
CIS3 and JAB have different regulatory roles in interleukin-6 mediated differentiation and STAT3 activation in M1 leukemia cells. Oncogene (1998) 1.13
scFv multimers of the anti-neuraminidase antibody NC10: length of the linker between VH and VL domains dictates precisely the transition between diabodies and triabodies. Protein Eng (1999) 1.13
Endoscopic subtotal thyroidectomy for patients with Graves' disease. Surg Today (2001) 1.13
Soft tissue cephalometric norms in Japanese adults. Am J Orthod Dentofacial Orthop (2000) 1.11
Chronic thyroiditis as a favorable prognostic factor in papillary thyroid carcinoma. Thyroid (1998) 1.11
Dlxin-1, a novel protein that binds Dlx5 and regulates its transcriptional function. J Biol Chem (2000) 1.09
Patterns of parasite aggregation in the wild European rabbit (Oryctolagus cuniculus). Int J Parasitol (2001) 1.08
Birnavirus precursor polyprotein is processed in Escherichia coli by its own virus-encoded polypeptide. J Virol (1988) 1.08
Immunoreactive corticotropin-releasing factor is present in human maternal plasma during the third trimester of pregnancy. J Clin Endocrinol Metab (1984) 1.07
Development of diabetes in Japanese subjects with impaired glucose tolerance: a seven year follow-up study. Diabetologia (1982) 1.07
Cloning, mapping, expression, function, and mutation analyses of the human ortholog of the hamster putative tumor suppressor gene Doc-1. J Biol Chem (1998) 1.07
Single-chain Fv fragments of anti-neuraminidase antibody NC10 containing five- and ten-residue linkers form dimers and with zero-residue linker a trimer. Protein Eng (1997) 1.07
Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor. Proc Natl Acad Sci U S A (2004) 1.06
Connective tissue growth factor as a major angiogenic agent that is induced by hypoxia in a human breast cancer cell line. Cancer Lett (2001) 1.06
Evidence for school transmission of Neisseria meningitidis during a Vermont outbreak. Pediatr Infect Dis (1986) 1.06
Predictors and prognostic significance of operative complications in patients with hepatocellular carcinoma who underwent hepatic resection. Eur J Surg Oncol (2009) 1.06
Evolutionary pattern of intra-host pathogen antigenic drift: effect of cross-reactivity in immune response. Philos Trans R Soc Lond B Biol Sci (1997) 1.05
Habitat loss and raptor predation: disentangling long- and short-term causes of red grouse declines. Proc Biol Sci (2000) 1.05
8-hydroxyguanine (7,8-dihydro-8-oxoguanine) DNA glycosylase and AP lyase activities of hOGG1 protein and their substrate specificity. Mutat Res (1997) 1.05
Prognosis of patients with intrahepatic recurrence after hepatic resection for hepatocellular carcinoma: a retrospective study. Eur J Surg Oncol (2008) 1.05
Isolation of the new antigen receptor from wobbegong sharks, and use as a scaffold for the display of protein loop libraries. Mol Immunol (2001) 1.05
Pyruvate carboxylase: mechanism on the second partial reaction. Arch Biochem Biophys (1976) 1.04
Esophageal carcinosarcoma: a genetic analysis. Gastroenterology (1997) 1.04
Parasite co-infection and interaction as drivers of host heterogeneity. Int J Parasitol (2007) 1.04
Body fatness and fat distribution as predictors of metabolic abnormalities and early carotid atherosclerosis. Diabetes Care (2001) 1.04
Hantavirus and arenavirus antibody prevalence in rodents and humans in Trentino, Northern Italy. Epidemiol Infect (2005) 1.03
Molecular epidemiology of Rabbit haemorrhagic disease virus. J Gen Virol (2002) 1.01
Interleukin-6 and cardiac myxoma. Am J Cardiol (1994) 1.01
Skewed X chromosome inactivation failed to explain the normal phenotype of a carrier female with MECP2 mutation resulting in Rett syndrome. Clin Genet (2007) 1.01
Sequence of the small double-stranded RNA genomic segment of infectious bursal disease virus and its deduced 90-kDa product. Virology (1988) 1.00
Involvement of CTGF, a hypertrophic chondrocyte-specific gene product, in tumor angiogenesis. Oncology (2001) 1.00
Bronchobiliary fistula presenting as cough with yellow sputum. N Engl J Med (1982) 1.00
Accumulation of beta-amyloid fibrils in pancreas of transgenic mice. Neurobiol Aging (1996) 1.00
Reduced tau expression in gastric cancer can identify candidates for successful Paclitaxel treatment. Br J Cancer (2006) 1.00
The E-cadherin gene is silenced by CpG methylation in human oral squamous cell carcinomas. Int J Cancer (2001) 0.99
Ribonuclease from Streptomyces erythreus. Purification and properties. Biochim Biophys Acta (1971) 0.98
Presence of human cellular protein(s) that specifically binds and cleaves 8-hydroxyguanine containing DNA. Mutat Res (1997) 0.98
Duration of whirlpool-spa use as a risk factor for Pseudomonas dermatitis. Am J Epidemiol (1985) 0.98
Optimal recombination rate in fluctuating environments. Genetics (1987) 0.98
Suppressor of cytokine signalling 1 in lymphocytes regulates the development of intestinal inflammation in mice. Gut (2005) 0.98
Effects of elemental mercury exposure at a thermometer plant. Am J Ind Med (1991) 0.98
Expansion of an ablated site and induction of apoptosis after microwave coagulation therapy in rat liver. J Hepatobiliary Pancreat Surg (2001) 0.98
Patterns of genetic polymorphism maintained by fluctuating selection with overlapping generations. Theor Popul Biol (1996) 0.97
A Reovirus Causes Hypovirulence of Rosellinia necatrix. Phytopathology (2004) 0.97
Transmission of louping ill virus between infected and uninfected ticks co-feeding on mountain hares. Med Vet Entomol (1997) 0.96
Orthotopic, but reversed implantation of the liver allograft in situs inversus totalis-a simple new approach to a difficult problem. Am J Transplant (2009) 0.96
Association between serum leptin concentrations and bone mineral density, and biochemical markers of bone turnover in adult men. J Clin Endocrinol Metab (2001) 0.95
Correlation of thrombospondin-1 and transforming growth factor-beta expression with malignancy of glioma. Neuropathology (2000) 0.95
Patterns of cercarial production from Diplostomum spathaceum: terminal investment or bet hedging? Parasitology (2004) 0.95
Human GLUT5 immunolabeling is useful for evaluating microglial status in neuropathological study using paraffin sections. Acta Neuropathol (2002) 0.95