Published in Cancer Res on February 01, 2004
Phase I - Pre-Radical Prostatectomy RTVP-1 Gene Therapy for Prostate Cancer | NCT00403221
Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. Neoplasia (2007) 1.03
GLIPR1 tumor suppressor gene expressed by adenoviral vector as neoadjuvant intraprostatic injection for localized intermediate or high-risk prostate cancer preceding radical prostatectomy. Clin Cancer Res (2011) 1.00
GLIPR1 suppresses prostate cancer development through targeted oncoprotein destruction. Cancer Res (2011) 0.98
Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by methyl-CpG binding proteins and histone modifications. BMC Cancer (2010) 0.96
Epigenetic mechanisms of promigratory chemokine CXCL14 regulation in human prostate cancer cells. Cancer Res (2010) 0.93
Identification of GLIPR1 tumor suppressor as methylation-silenced gene in acute myeloid leukemia by microarray analysis. J Cancer Res Clin Oncol (2011) 0.92
Glioma pathogenesis-related protein 1: tumor-suppressor activities and therapeutic potential. Yonsei Med J (2010) 0.92
Variable Expression of GLIPR1 Correlates with Invasive Potential in Melanoma Cells. Front Oncol (2013) 0.91
Structural studies of human glioma pathogenesis-related protein 1. Acta Crystallogr D Biol Crystallogr (2011) 0.86
Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2. Mol Oncol (2012) 0.86
TGF-β mediated DNA methylation in prostate cancer. Transl Androl Urol (2012) 0.85
Systemic GLIPR1-ΔTM protein as a novel therapeutic approach for prostate cancer. Int J Cancer (2013) 0.84
GLIPR1-ΔTM synergizes with docetaxel in cell death and suppresses resistance to docetaxel in prostate cancer cells. Mol Cancer (2015) 0.83
Tumor growth and metastasis suppression by Glipr1 gene-modified macrophages in a metastatic prostate cancer model. Gene Ther (2011) 0.82
MMTV promoter-regulated caveolin-1 overexpression yields defective parenchymal epithelia in multiple exocrine organs of transgenic mice. Exp Mol Pathol (2010) 0.81
GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancer. Mol Cancer (2016) 0.80
Inhibition of HIV-1 replication by small interfering RNAs directed against glioma pathogenesis related protein (GliPR) expression. Retrovirology (2010) 0.80
Expression, purification, crystallization and preliminary X-ray analysis of a truncated soluble domain of human glioma pathogenesis-related protein 1. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.79
Combined therapeutic effects of adenoviral vector-mediated GLIPR1 gene therapy and radiotherapy in prostate and bladder cancer models. Urol Oncol (2013) 0.78
Related to testes-specific, vespid and pathogenesis protein-1 is regulated by methylation in glioblastoma. Oncol Lett (2014) 0.78
SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1. PLoS One (2015) 0.78
Potential therapeutic mechanism of genistein in breast cancer involves inhibition of cell cycle regulation. Mol Med Rep (2014) 0.76
RTVP-1 regulates glioma cell migration and invasion via interaction with N-WASP and hnRNPK. Oncotarget (2015) 0.76
GLIPR1 modulates the response of cisplatin-resistant human lung cancer cells to cisplatin. PLoS One (2017) 0.75
ATP mediates rapid microglial response to local brain injury in vivo. Nat Neurosci (2005) 11.55
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature (2013) 5.35
The P2Y12 receptor regulates microglial activation by extracellular nucleotides. Nat Neurosci (2006) 4.93
MYD88 L265P somatic mutation in Waldenström's macroglobulinemia. N Engl J Med (2012) 4.26
Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex. Nat Neurosci (2007) 3.92
Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma. J Invest Dermatol (2004) 3.80
Pathobiology of autochthonous prostate cancer in a pre-clinical transgenic mouse model. Prostate (2003) 3.44
Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex. Nature (2005) 3.41
High levels of phosphorylated form of Akt-1 in prostate cancer and non-neoplastic prostate tissues are strong predictors of biochemical recurrence. Clin Cancer Res (2004) 2.75
A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling. Cancer Res (2007) 2.52
Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation. Nucleic Acids Res (2008) 2.44
Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma. Blood (2012) 2.29
Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2. J Neurosci (2005) 2.21
Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A. Mol Cell Biol (2003) 2.20
Role of SRC-1 in the promotion of prostate cancer cell growth and tumor progression. Cancer Res (2005) 2.14
A heterozygous moth genome provides insights into herbivory and detoxification. Nat Genet (2013) 2.13
COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis. Nature (2012) 2.11
Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress. J Biol Chem (2007) 2.08
Ibrutinib in previously treated Waldenström's macroglobulinemia. N Engl J Med (2015) 2.04
AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec. Proc Natl Acad Sci U S A (2005) 2.03
CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer. Clin Cancer Res (2007) 1.94
Recurrent chimeric RNAs enriched in human prostate cancer identified by deep sequencing. Proc Natl Acad Sci U S A (2011) 1.94
Altered adipose and plasma sphingolipid metabolism in obesity: a potential mechanism for cardiovascular and metabolic risk. Diabetes (2006) 1.91
Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. Cancer Res (2006) 1.90
Somatic mutations in MYD88 and CXCR4 are determinants of clinical presentation and overall survival in Waldenstrom macroglobulinemia. Blood (2014) 1.89
Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival. Clin Cancer Res (2002) 1.89
Design and characterization of a spatially distributed multibeam field emission x-ray source for stationary digital breast tomosynthesis. Med Phys (2009) 1.80
The lectin-like domain of tumor necrosis factor improves lung function after rat lung transplantation--potential role for a reduction in reactive oxygen species generation. Crit Care Med (2010) 1.78
Growth and survival mechanisms associated with perineural invasion in prostate cancer. Cancer Res (2004) 1.77
A supermatrix analysis of genomic, morphological, and paleontological data from crown Cetacea. BMC Evol Biol (2011) 1.74
Single-stranded DNA aptamers that bind differentiated but not parental cells: subtractive systematic evolution of ligands by exponential enrichment. J Biotechnol (2003) 1.67
Correlative evidence that prostate cancer cell-derived caveolin-1 mediates angiogenesis. Hum Pathol (2007) 1.66
Hypoxic adipocytes pattern early heterotopic bone formation. Am J Pathol (2007) 1.62
Herd behavior in a complex adaptive system. Proc Natl Acad Sci U S A (2011) 1.62
High resolution stationary digital breast tomosynthesis using distributed carbon nanotube x-ray source array. Med Phys (2012) 1.58
Cancer-related axonogenesis and neurogenesis in prostate cancer. Clin Cancer Res (2008) 1.56
Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1. J Biol Chem (2008) 1.55
Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Cell Stem Cell (2013) 1.55
Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2. Cell Metab (2013) 1.54
Sustained long-term immune responses after in situ gene therapy combined with radiotherapy and hormonal therapy in prostate cancer patients. Int J Radiat Oncol Biol Phys (2006) 1.50
Association between physical activity and urinary incontinence in a community-based elderly population aged 70 years and over. Eur Urol (2007) 1.49
[Effects of Rhaponticum uniforum polysaccharide on immune response of mice after antigen stimulation and their possible mechanisms]. Zhongguo Zhong Yao Za Zhi (2007) 1.44
Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin. Proc Natl Acad Sci U S A (2013) 1.43
Permanent Genetic Resources added to Molecular Ecology Resources Database 1 August 2009-30 September 2009. Mol Ecol Resour (2010) 1.39
IL-17A and TNF-α exert synergistic effects on expression of CXCL5 by alveolar type II cells in vivo and in vitro. J Immunol (2011) 1.37
Tumor cell-secreted caveolin-1 has proangiogenic activities in prostate cancer. Cancer Res (2008) 1.37
Relaxin promotes prostate cancer progression. Clin Cancer Res (2007) 1.34
Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer. Cancer Res (2011) 1.32
Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation. Nat Med (2011) 1.31
SENP1 induces prostatic intraepithelial neoplasia through multiple mechanisms. J Biol Chem (2010) 1.29
Covalent bulk functionalization of graphene. Nat Chem (2011) 1.28
mRTVP-1, a novel p53 target gene with proapoptotic activities. Mol Cell Biol (2002) 1.27
Altered fibroblast growth factor receptor 4 stability promotes prostate cancer progression. Neoplasia (2008) 1.26
Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res (2006) 1.24
Glioma pathogenesis-related protein 1 exerts tumor suppressor activities through proapoptotic reactive oxygen species-c-Jun-NH2 kinase signaling. Cancer Res (2008) 1.24
Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling. EMBO J (2006) 1.22
Development of an immunoassay for serum caveolin-1: a novel biomarker for prostate cancer. Clin Cancer Res (2003) 1.22
Transthyretin constitutes a functional component in pancreatic beta-cell stimulus-secretion coupling. Proc Natl Acad Sci U S A (2005) 1.22
Common structural and epigenetic changes in the genome of castration-resistant prostate cancer. Cancer Res (2011) 1.21
An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1. J Clin Invest (2014) 1.19
Influence of decellularized matrix derived from human mesenchymal stem cells on their proliferation, migration and multi-lineage differentiation potential. Biomaterials (2012) 1.18
Stromal antiapoptotic paracrine loop in perineural invasion of prostatic carcinoma. Cancer Res (2006) 1.17
Seven new dolphin mitochondrial genomes and a time-calibrated phylogeny of whales. BMC Evol Biol (2009) 1.17
Chlamydial CT441 is a PDZ domain-containing tail-specific protease that interferes with the NF-kappaB pathway of immune response. J Bacteriol (2007) 1.17
Notch and TGFβ form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity. Cell Stem Cell (2012) 1.16
Disruption of the caveolin-1 gene impairs renal calcium reabsorption and leads to hypercalciuria and urolithiasis. Am J Pathol (2003) 1.16
Haff disease after eating crayfish in east China. Intern Med (2012) 1.16
Preoperative serum caveolin-1 as a prognostic marker for recurrence in a radical prostatectomy cohort. Clin Cancer Res (2006) 1.16
MicroRNA-200b regulates cyclin D1 expression and promotes S-phase entry by targeting RND3 in HeLa cells. Mol Cell Biochem (2010) 1.15
Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death. Int J Cancer (2008) 1.15
FGFR1 is essential for prostate cancer progression and metastasis. Cancer Res (2013) 1.14
Asiatic acid inhibits liver fibrosis by blocking TGF-beta/Smad signaling in vivo and in vitro. PLoS One (2012) 1.14
Agonist of growth hormone-releasing hormone reduces pneumolysin-induced pulmonary permeability edema. Proc Natl Acad Sci U S A (2012) 1.14
N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of novel orthopoxvirus egress inhibitors. J Med Chem (2007) 1.13
Risk-return relationship in a complex adaptive system. PLoS One (2012) 1.13
Phylogenomic analysis resolves the interordinal relationships and rapid diversification of the laurasiatherian mammals. Syst Biol (2011) 1.12
Lack of association of two common polymorphisms rs2910164 and rs11614913 with susceptibility to hepatocellular carcinoma: a meta-analysis. PLoS One (2012) 1.12
Delay in initiation and termination of muscle contraction, motor impairment, and physical disability in upper limb hemiparesis. Muscle Nerve (2002) 1.12
Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy. Mol Ther (2007) 1.12
Developmental and insecticide-resistant insights from the de novo assembled transcriptome of the diamondback moth, Plutella xylostella. Genomics (2012) 1.11
Muscle weakness and cocontraction in upper limb hemiparesis: relationship to motor impairment and physical disability. Neurorehabil Neural Repair (2002) 1.11
Identification and characterization of RTVP1/GLIPR1-like genes, a novel p53 target gene cluster. Genomics (2006) 1.09
Hfq is a global regulator that controls the pathogenicity of Staphylococcus aureus. PLoS One (2010) 1.09
Using caveolin-1 knockout mouse to study impaired detrusor contractility and disrupted muscarinic activity in the aging bladder. Urology (2007) 1.09