Published in Nucleic Acids Res on February 18, 2004
The structural basis of myotonic dystrophy from the crystal structure of CUG repeats. Proc Natl Acad Sci U S A (2005) 1.96
Structural insights into CUG repeats containing the 'stretched U-U wobble': implications for myotonic dystrophy. Nucleic Acids Res (2009) 1.28
TEDOR with adiabatic inversion pulses: Resonance assignments of 13C/15N labelled RNAs. J Biomol NMR (2005) 0.95
Design of high-power, broadband 180 degrees pulses and mixing sequences for fast MAS solid state chemical shift correlation NMR spectroscopy. J Biomol NMR (2008) 0.93
Homonuclear chemical shift correlation in rotating solids via RNnu n symmetry-based adiabatic RF pulse schemes. J Biomol NMR (2004) 0.86
MAS solid state NMR of RNAs with multiple receivers. J Biomol NMR (2008) 0.83
RNA structure determination by solid-state NMR spectroscopy. Nat Commun (2015) 0.83
Characterisation of hydrogen bonding networks in RNAs via magic angle spinning solid state NMR spectroscopy. J Biomol NMR (2005) 0.82
Broadband homonuclear chemical shift correlation at high MAS frequencies: a study of tanh/tan adiabatic RF pulse schemes without 1H decoupling during mixing. J Biomol NMR (2007) 0.81
Tailoring broadband inversion pulses for MAS solid state NMR. J Biomol NMR (2006) 0.78
Synthesis and characterization of a [3-15N]-labeled cis-syn thymine dimer-containing DNA duplex. J Org Chem (2006) 0.78
Nucleotide-type chemical shift assignment of the encapsulated 40 kbp dsDNA in intact bacteriophage T7 by MAS solid-state NMR. J Biomol NMR (2014) 0.77
Evaluation of (15)N-detected H-N correlation experiments on increasingly large RNAs. J Biomol NMR (2017) 0.75
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science (2000) 28.25
Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member. Cell (1992) 12.74
Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy. EMBO J (2000) 6.56
A muscleblind knockout model for myotonic dystrophy. Science (2003) 5.93
Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy. Mol Cell (2002) 4.44
Structure of a protein determined by solid-state magic-angle-spinning NMR spectroscopy. Nature (2002) 4.29
Loss of the muscle-specific chloride channel in type 1 myotonic dystrophy due to misregulated alternative splicing. Mol Cell (2002) 4.05
SIMPSON: a general simulation program for solid-state NMR spectroscopy. J Magn Reson (2000) 4.04
Preparation of isotopically labeled ribonucleotides for multidimensional NMR spectroscopy of RNA. Nucleic Acids Res (1992) 3.29
Dipolar recoupling in MAS spectra of biological solids. Nat Struct Biol (1998) 3.26
NMR spectroscopy of RNA. Chembiochem (2003) 2.49
Stitching together RNA tertiary architectures. J Mol Biol (1999) 2.40
CUG repeats present in myotonin kinase RNA form metastable "slippery" hairpins. J Biol Chem (1997) 2.17
Backbone and side-chain 13C and 15N signal assignments of the alpha-spectrin SH3 domain by magic angle spinning solid-state NMR at 17.6 Tesla. Chembiochem (2001) 2.08
Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein. Nucleic Acids Res (1999) 1.85
Partial NMR assignments for uniformly (13C, 15N)-enriched BPTI in the solid state. J Biomol NMR (2000) 1.62
NMR study of 100 kDa HCV IRES RNA using segmental isotope labeling. J Am Chem Soc (2002) 1.47
Assignment methodology for larger RNA oligonucleotides: application to an ATP-binding RNA aptamer. J Biomol NMR (1997) 1.42
The NMR structure of the 5S rRNA E-domain-protein L25 complex shows preformed and induced recognition. EMBO J (1999) 1.39
The structure of the stemloop D subdomain of coxsackievirus B3 cloverleaf RNA and its interaction with the proteinase 3C. Structure (2004) 1.27
Sample optimization and identification of signal patterns of amino acid side chains in 2D RFDR spectra of the alpha-spectrin SH3 domain. J Magn Reson (2000) 1.13
1H detection in MAS solid-state NMR spectroscopy of biomacromolecules employing pulsed field gradients for residual solvent suppression. J Am Chem Soc (2003) 1.12
Direct identification of NH...N hydrogen bonds in non-canonical base pairs of RNA by NMR spectroscopy. Nucleic Acids Res (1999) 1.11
Scalar couplings across hydrogen bonds. Methods Enzymol (2001) 1.10
Broadband RFDR with adiabatic inversion pulses. J Biomol NMR (2003) 1.08
Determining RNA solution structure by segmental isotopic labeling and NMR: application to Caenorhabditis elegans spliced leader RNA 1. Proc Natl Acad Sci U S A (1996) 1.04
Chemical shift correlation via RFDR: elimination of resonance offset effects. J Biomol NMR (2002) 0.97
Synthesis and NMR of RNA with selective isotopic enrichment in the bases. Nucleic Acids Res (1995) 0.93
Measurement of NH bond lengths by fast magic-angle spinning solid-state NMR spectroscopy: a new method for the quantification of hydrogen bonds. J Am Chem Soc (2001) 0.90
A 3-D structural model of solid self-assembled chlorophyll a/H(2)O from multispin labeling and MAS NMR 2-D dipolar correlation spectroscopy in high magnetic field. J Magn Reson (2002) 0.88
Structure of a U.U pair within a conserved ribosomal RNA hairpin. Nucleic Acids Res (1996) 0.88
RFDR with adiabatic inversion pulses: application to internuclear distance measurements. J Biomol NMR (2004) 0.85
The accuracy of distance measurements in solid-state NMR. J Magn Reson (1999) 0.83
A muscleblind knockout model for myotonic dystrophy. Science (2003) 5.93
Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy. Hum Mol Genet (2006) 4.35
Muscleblind proteins regulate alternative splicing. EMBO J (2004) 4.01
Non-ATG-initiated translation directed by microsatellite expansions. Proc Natl Acad Sci U S A (2010) 3.58
Alternative conformations of HIV-1 V3 loops mimic beta hairpins in chemokines, suggesting a mechanism for coreceptor selectivity. Structure (2003) 3.32
Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons. Hum Mol Genet (2004) 3.21
Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy. Proc Natl Acad Sci U S A (2006) 3.09
Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy. Nat Struct Mol Biol (2010) 3.07
Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs. Nucleic Acids Res (2007) 2.95
Essential role for Dicer during skeletal muscle development. Dev Biol (2007) 2.76
Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy. J Clin Invest (2007) 2.68
RNA gain-of-function in spinocerebellar ataxia type 8. PLoS Genet (2009) 2.45
Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy. J Cell Sci (2005) 2.31
RNA localization in yeast: moving towards a mechanism. Biol Cell (2005) 2.15
Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear export. EMBO J (2002) 2.07
Small molecule regulators of protein arginine methyltransferases. J Biol Chem (2004) 1.99
Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development. Dev Dyn (2005) 1.95
Muscle chloride channel dysfunction in two mouse models of myotonic dystrophy. J Gen Physiol (2006) 1.83
Transcriptional and post-transcriptional impact of toxic RNA in myotonic dystrophy. Hum Mol Genet (2009) 1.80
Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy. Neuron (2012) 1.78
Mechanisms of RNA-mediated disease. J Biol Chem (2008) 1.59
Nuclear RNA foci in the heart in myotonic dystrophy. Circ Res (2005) 1.57
Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3. Gene Expr Patterns (2003) 1.49
Partners in crime: bidirectional transcription in unstable microsatellite disease. Hum Mol Genet (2010) 1.37
DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in an RNA-dependent manner. Nucleic Acids Res (2004) 1.31
The structure of the stemloop D subdomain of coxsackievirus B3 cloverleaf RNA and its interaction with the proteinase 3C. Structure (2004) 1.27
Splicing biomarkers of disease severity in myotonic dystrophy. Ann Neurol (2013) 1.22
Myosin light chain phosphorylation is critical for adaptation to cardiac stress. Circulation (2012) 1.19
Compound loss of muscleblind-like function in myotonic dystrophy. EMBO Mol Med (2013) 1.19
Developments in RNA splicing and disease. Cold Spring Harb Perspect Biol (2011) 1.18
Toxic RNA in the nucleus: unstable microsatellite expression in neuromuscular disease. Prog Mol Subcell Biol (2004) 1.09
Broadband RFDR with adiabatic inversion pulses. J Biomol NMR (2003) 1.08
Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brain. PLoS One (2012) 1.05
Prediction of clustered RNA-binding protein motif sites in the mammalian genome. Nucleic Acids Res (2013) 1.05
Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch. Angew Chem Int Ed Engl (2010) 1.05
Pathogenic RNAs in microsatellite expansion disease. Neurosci Lett (2009) 1.01
Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C. RNA (2002) 1.01
CAPITO--a web server-based analysis and plotting tool for circular dichroism data. Bioinformatics (2013) 0.99
Muscleblind isoforms are functionally distinct and regulate alpha-actinin splicing. Differentiation (2007) 0.99
MicroRNAs in mammalian development and tumorigenesis. Birth Defects Res C Embryo Today (2006) 0.97
Chemical shift correlation via RFDR: elimination of resonance offset effects. J Biomol NMR (2002) 0.97
Structural basis of β-amyloid-dependent synaptic dysfunctions. Angew Chem Int Ed Engl (2012) 0.96
Yeast mRNA Poly(A) tail length control can be reconstituted in vitro in the absence of Pab1p-dependent Poly(A) nuclease activity. J Biol Chem (2005) 0.95
TEDOR with adiabatic inversion pulses: Resonance assignments of 13C/15N labelled RNAs. J Biomol NMR (2005) 0.95
REDOR: an assessment of the efficacy of dipolar recoupling with adiabatic inversion pulses. J Biomol NMR (2002) 0.95
A novel cGUUAg tetraloop structure with a conserved yYNMGg-type backbone conformation from cloverleaf 1 of bovine enterovirus 1 RNA. Nucleic Acids Res (2005) 0.94
Design of high-power, broadband 180 degrees pulses and mixing sequences for fast MAS solid state chemical shift correlation NMR spectroscopy. J Biomol NMR (2008) 0.93
Three-dimensional structure of the S4-S5 segment of the Shaker potassium channel. Biophys J (2002) 0.93
NMR solution structure of a parallel LNA quadruplex. Nucleic Acids Res (2004) 0.93
Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice. Hum Mol Genet (2013) 0.92
Adiabatic TOBSY in rotating solids. J Biomol NMR (2004) 0.92
Molecular basis of β-amyloid oligomer recognition with a conformational antibody fragment. Proc Natl Acad Sci U S A (2012) 0.91
Interaction of Kazal-type inhibitor domains with serine proteinases: biochemical and structural studies. J Mol Biol (2002) 0.90
Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV 1.4. Angew Chem Int Ed Engl (2012) 0.90
Solution structure of a functional biomimetic and mechanistic implications for nickel superoxide dismutases. Chembiochem (2008) 0.89
Nuclear DNA helicase II/RNA helicase A binds to filamentous actin. J Biol Chem (2001) 0.88
Nitric oxide donors inhibit the coxsackievirus B3 proteinases 2A and 3C in vitro, virus production in cells, and signs of myocarditis in virus-infected mice. Med Microbiol Immunol (2003) 0.88
Structural studies on LNA quadruplexes. Nucleosides Nucleotides Nucleic Acids (2005) 0.87
The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif. Nucleic Acids Res (2012) 0.87
Solid state NMR of proteins at high MAS frequencies: symmetry-based mixing and simultaneous acquisition of chemical shift correlation spectra. J Biomol NMR (2012) 0.86
Poly(rC)-binding protein 2 interacts with the oligo(rC) tract of coxsackievirus B3. Biochem Biophys Res Commun (2007) 0.86
Homonuclear chemical shift correlation in rotating solids via RNnu n symmetry-based adiabatic RF pulse schemes. J Biomol NMR (2004) 0.86
RFDR with adiabatic inversion pulses: application to internuclear distance measurements. J Biomol NMR (2004) 0.85
Analysis of Fe(III) heme binding to cysteine-containing heme-regulatory motifs in proteins. ACS Chem Biol (2013) 0.85