Published in J Immunol on April 01, 2004
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Establishment of an enzyme-linked immunosorbent assay system for determining soluble CD96 and its application in the measurement of sCD96 in patients with viral hepatitis B and hepatic cirrhosis. Clin Exp Immunol (2008) 0.78
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Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation. J Immunol (2006) 4.87
T cell receptor signaling precedes immunological synapse formation. Science (2002) 4.56
TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function. Immunity (2004) 4.50
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant. J Exp Med (2009) 4.27
Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity (2004) 4.11
Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii. Immunity (2008) 4.07
Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9. Blood (2003) 3.98
CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility. Science (2003) 3.61
Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-γ-producing cells. Immunity (2013) 3.51
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest (2010) 3.44
Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells. Eur J Immunol (2004) 3.25
Cutting edge: TREM-2 attenuates macrophage activation. J Immunol (2006) 3.07
The TREM receptor family and signal integration. Nat Immunol (2006) 3.06
AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. Nat Immunol (2011) 2.99
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP. J Exp Med (2009) 2.92
NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation. Nat Immunol (2002) 2.92
Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling. Mol Cell Biol (2003) 2.69
NK cell and DC interactions. Trends Immunol (2004) 2.68
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia. Nat Immunol (2012) 2.62
The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine. Proc Natl Acad Sci U S A (2008) 2.57
Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8(+) T cell accrual. Immunity (2010) 2.56
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Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo. Mol Cell Biol (2002) 2.54
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A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response. J Immunol (2003) 2.42
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Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proc Natl Acad Sci U S A (2003) 2.33
HLA alleles determine differences in human natural killer cell responsiveness and potency. Proc Natl Acad Sci U S A (2008) 2.31
The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality. Immunity (2008) 2.13
Podocytes use FcRn to clear IgG from the glomerular basement membrane. Proc Natl Acad Sci U S A (2008) 2.12
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Efficient colonic mucosal wound repair requires Trem2 signaling. Proc Natl Acad Sci U S A (2008) 1.93
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Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin. Nat Immunol (2009) 1.88
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Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol (2013) 1.87
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Type I IFN controls chikungunya virus via its action on nonhematopoietic cells. J Exp Med (2010) 1.86
Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T cells by 1,25-dihydroxyvitamin D3. Blood (2005) 1.83
Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis. J Clin Invest (2011) 1.81
Impaired differentiation of osteoclasts in TREM-2-deficient individuals. J Exp Med (2003) 1.80
Development and function of murine B220+CD11c+NK1.1+ cells identify them as a subset of NK cells. J Exp Med (2007) 1.76
Use of genetic profiling in leprosy to discriminate clinical forms of the disease. Science (2003) 1.73
Evidence for MR1 antigen presentation to mucosal-associated invariant T cells. J Biol Chem (2005) 1.72
Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia. Eur J Neurosci (2004) 1.71
A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis. J Biol Chem (2004) 1.70
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MDA-5 recognition of a murine norovirus. PLoS Pathog (2008) 1.68
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Interferon-producing cells: on the front line in immune responses against pathogens. Curr Opin Immunol (2002) 1.67
Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. PLoS Pathog (2010) 1.66
Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells. J Clin Invest (2012) 1.66
Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin. J Clin Invest (2006) 1.66
Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways. Eur J Immunol (2005) 1.62
Murine vascular endothelium activates and induces the generation of allogeneic CD4+25+Foxp3+ regulatory T cells. J Immunol (2005) 1.61
Hidden talents of natural killers: NK cells in innate and adaptive immunity. EMBO Rep (2009) 1.60
Allosteric activation of functionally asymmetric RAF kinase dimers. Cell (2013) 1.60
Novel markers of normal and neoplastic human plasmacytoid dendritic cells. Blood (2008) 1.58
Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals. Gastroenterology (2013) 1.57
Understanding the structure and function of the immunological synapse. Cold Spring Harb Perspect Biol (2010) 1.54
Timing and magnitude of type I interferon responses by distinct sensors impact CD8 T cell exhaustion and chronic viral infection. Cell Host Microbe (2012) 1.54
Interferon-producing cells fail to induce proliferation of naive T cells but can promote expansion and T helper 1 differentiation of antigen-experienced unpolarized T cells. J Exp Med (2003) 1.54
Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response. J Exp Med (2010) 1.54
KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity. Cell Metab (2009) 1.53
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