Published in Nat Rev Cancer on April 01, 2004
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell (2010) 8.70
Formation and repair of interstrand cross-links in DNA. Chem Rev (2006) 2.91
Susceptibility pathways in Fanconi's anemia and breast cancer. N Engl J Med (2010) 2.79
FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway. EMBO J (2007) 2.00
Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women. Breast Cancer Res (2007) 2.00
BRCA1 and BRCA2: chemosensitivity, treatment outcomes and prognosis. Fam Cancer (2006) 1.65
Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability. EMBO J (2007) 1.65
Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination. Mol Cell Biol (2005) 1.65
Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM. EMBO J (2004) 1.56
Centrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitination. Mol Cell Biol (2005) 1.33
Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair. EMBO J (2012) 1.30
Pathology of hereditary breast cancer. Cell Oncol (Dordr) (2011) 1.28
Collaboration of Werner syndrome protein and BRCA1 in cellular responses to DNA interstrand cross-links. Nucleic Acids Res (2006) 1.26
The mTOR inhibitor rapamycin suppresses DNA double-strand break repair. Radiat Res (2010) 1.25
The role of RPA2 phosphorylation in homologous recombination in response to replication arrest. Carcinogenesis (2010) 1.14
The Fanconi anemia pathway and ubiquitin. BMC Biochem (2007) 1.10
Genetic predictors of taxane-induced neurotoxicity in a SWOG phase III intergroup adjuvant breast cancer treatment trial (S0221). Breast Cancer Res Treat (2011) 1.10
The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system. Nat Rev Cancer (2008) 1.08
Formaldehyde and leukemia: epidemiology, potential mechanisms, and implications for risk assessment. Environ Mol Mutagen (2010) 1.07
PALB2 sequence variants in young South African breast cancer patients. Fam Cancer (2009) 1.07
mTOR regulates DNA damage response through NF-κB-mediated FANCD2 pathway in hematopoietic cells. Leukemia (2013) 1.07
FANCJ helicase operates in the Fanconi Anemia DNA repair pathway and the response to replicational stress. Curr Mol Med (2009) 1.00
Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1. Blood (2005) 0.96
Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility. J Biol Chem (2011) 0.95
Chromosomal instability in the lymphocytes of breast cancer patients. Indian J Hum Genet (2009) 0.90
Mutation analysis and characterization of ATR sequence variants in breast cancer cases from high-risk French Canadian breast/ovarian cancer families. BMC Cancer (2006) 0.90
Adding pharmacogenomics to the development of new marine-derived anticancer agents. J Transl Med (2006) 0.90
BRCA1, FANCD2 and Chk1 are potential molecular targets for the modulation of a radiation-induced DNA damage response in bystander cells. Cancer Lett (2014) 0.89
Brca1 in immunoglobulin gene conversion and somatic hypermutation. DNA Repair (Amst) (2007) 0.88
The breast cancer susceptibility gene BRCA2 is required for the maintenance of telomere homeostasis. J Biol Chem (2011) 0.88
Context dependence of checkpoint kinase 1 as a therapeutic target for pancreatic cancers deficient in the BRCA2 tumor suppressor. Mol Cancer Ther (2011) 0.87
Loss of expression of FANCD2 protein in sporadic and hereditary breast cancer. Breast Cancer Res Treat (2007) 0.84
The Fanconi anemia pathway and DNA interstrand cross-link repair. Protein Cell (2011) 0.83
A PP1-binding motif present in BRCA1 plays a role in its DNA repair function. Int J Biol Sci (2008) 0.83
Shared and unique properties of ubiquitin and SUMO interaction networks in DNA repair. Genes Dev (2011) 0.80
A genomic instability score in discriminating nonequivalent outcomes of BRCA1/2 mutations and in predicting outcomes of ovarian cancer treated with platinum-based chemotherapy. PLoS One (2014) 0.79
Dissecting systems-wide data using mixture models: application to identify affected cellular processes. BMC Bioinformatics (2005) 0.78
Rad18 is required for functional interactions between FANCD2, BRCA2, and Rad51 to repair DNA topoisomerase 1-poisons induced lesions and promote fork recovery. Oncotarget (2016) 0.77
RNF8-independent Lys63 poly-ubiquitylation prevents genomic instability in response to replication-associated DNA damage. PLoS One (2014) 0.77
Development of thymic lymphomas in mice disrupted of Brca2 allele in the thymus. Exp Mol Med (2008) 0.76
Peptide aptamer mimicking RAD51-binding domain of BRCA2 inhibits DNA damage repair and survival in Trypanosoma brucei. Microb Pathog (2011) 0.76
RAD51D- and FANCG-dependent base substitution mutagenesis at the ATP1A1 locus in mammalian cells. Mutat Res (2009) 0.75
Loss of RMI2 Increases Genome Instability and Causes a Bloom-Like Syndrome. PLoS Genet (2016) 0.75
Fanconi anemia-D1 due to homozygosity for the BRCA2 gene Cypriot founder mutation: A case report. Oncol Lett (2015) 0.75
Mtor-Fanconi Anemia DNA Damage Repair Pathway in Cancer. J Oncobiomarkers (2015) 0.75
[Hereditary breast and ovarian cancers]. Pathologe (2010) 0.75
The Role of Replication-Associated Repair Factors on R-Loops. Genes (Basel) (2017) 0.75
FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids. Nucleic Acids Res (2017) 0.75