|
1
|
IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses.
|
Proc Natl Acad Sci U S A
|
2007
|
3.98
|
|
2
|
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system.
|
Immunity
|
2008
|
3.67
|
|
3
|
ISG15, an interferon-stimulated ubiquitin-like protein, is not essential for STAT1 signaling and responses against vesicular stomatitis and lymphocytic choriomeningitis virus.
|
Mol Cell Biol
|
2005
|
2.31
|
|
4
|
Sialylation is essential for early development in mice.
|
Proc Natl Acad Sci U S A
|
2002
|
2.15
|
|
5
|
Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition.
|
Circ Res
|
2007
|
2.05
|
|
6
|
Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS.
|
Nat Neurosci
|
2011
|
1.96
|
|
7
|
Control of bone formation by the serpentine receptor Frizzled-9.
|
J Cell Biol
|
2011
|
1.77
|
|
8
|
Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo.
|
Mol Cell Biol
|
2007
|
1.76
|
|
9
|
Mouse gridlock: no aortic coarctation or deficiency, but fatal cardiac defects in Hey2 -/- mice.
|
Curr Biol
|
2002
|
1.70
|
|
10
|
Vaccinia virus E3 protein prevents the antiviral action of ISG15.
|
PLoS Pathog
|
2008
|
1.57
|
|
11
|
ISG15 regulates peritoneal macrophages functionality against viral infection.
|
PLoS Pathog
|
2013
|
1.51
|
|
12
|
IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system.
|
Brain
|
2011
|
1.37
|
|
13
|
Plasma membrane Ca2+ ATPase 4 is required for sperm motility and male fertility.
|
J Biol Chem
|
2004
|
1.37
|
|
14
|
Gastric hyperplasia in mice with targeted disruption of the carbonic anhydrase gene Car9.
|
Gastroenterology
|
2002
|
1.35
|
|
15
|
A regulatory role for CD37 in T cell proliferation.
|
J Immunol
|
2004
|
1.20
|
|
16
|
Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion.
|
EMBO J
|
2002
|
1.10
|
|
17
|
SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFNγ.
|
Blood
|
2011
|
1.08
|
|
18
|
Mice without the regulator gene Rsc1A1 exhibit increased Na+-D-glucose cotransport in small intestine and develop obesity.
|
Mol Cell Biol
|
2005
|
1.02
|
|
19
|
Cone versus rod disease in a mutant Rpgr mouse caused by different genetic backgrounds.
|
Invest Ophthalmol Vis Sci
|
2009
|
0.97
|
|
20
|
pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1.
|
Blood
|
2004
|
0.94
|
|
21
|
STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling.
|
Nat Immunol
|
2014
|
0.93
|
|
22
|
Type I interferons as ambiguous modulators of chronic inflammation in the central nervous system.
|
Front Immunol
|
2012
|
0.92
|
|
23
|
Gene disruption of Spred-2 causes dwarfism.
|
J Biol Chem
|
2005
|
0.90
|
|
24
|
Genetic targeting of microglia.
|
Glia
|
2014
|
0.90
|
|
25
|
HIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxia.
|
EMBO Rep
|
2013
|
0.88
|
|
26
|
Molecular characterization of ubiquitin-specific protease 18 reveals substrate specificity for interferon-stimulated gene 15.
|
FEBS J
|
2014
|
0.87
|
|
27
|
mHERC6 is the essential ISG15 E3 ligase in the murine system.
|
Biochem Biophys Res Commun
|
2011
|
0.85
|
|
28
|
Accumulation of c-Cbl and rapid termination of colony-stimulating factor 1 receptor signaling in interferon consensus sequence binding protein-deficient bone marrow-derived macrophages.
|
Blood
|
2002
|
0.83
|
|
29
|
Tissue-specific Spred-2 promoter activity characterized by a gene trap approach.
|
Gene Expr Patterns
|
2005
|
0.81
|
|
30
|
ISG15 modulates development of the erythroid lineage.
|
PLoS One
|
2011
|
0.80
|
|
31
|
Correction: ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection.
|
PLoS Pathog
|
2016
|
0.75
|
|
32
|
High yield expression of catalytically active USP18 (UBP43) using a Trigger Factor fusion system.
|
BMC Biotechnol
|
2012
|
0.75
|
|
33
|
Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.
|
Nat Immunol
|
2016
|
0.75
|