Published in Circ Res on February 15, 2007
Delta-Notch--and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Nucleic Acids Res (2007) 2.51
Slug is a direct Notch target required for initiation of cardiac cushion cellularization. J Cell Biol (2008) 2.21
Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation. J Clin Invest (2010) 1.54
Copy number analysis identifies novel interactions between genomic loci in ovarian cancer. PLoS One (2010) 1.50
Notch and the skeleton. Mol Cell Biol (2009) 1.49
Molecular insights into segmentation along the proximal-distal axis of the nephron. J Am Soc Nephrol (2007) 1.34
Inhibition of myogenesis by Notch: evidence for multiple pathways. J Cell Physiol (2009) 1.28
Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome. Development (2012) 1.21
Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers. Development (2011) 1.16
Inhibitory role of Notch1 in calcific aortic valve disease. PLoS One (2011) 1.13
The Notch effector Hey1 associates with myogenic target genes to repress myogenesis. J Biol Chem (2009) 1.11
Differential regulation of transforming growth factor beta signaling pathways by Notch in human endothelial cells. J Biol Chem (2009) 1.07
Association of common variants in ERBB4 with congenital left ventricular outflow tract obstruction defects. Birth Defects Res A Clin Mol Teratol (2011) 1.07
Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1. PLoS One (2009) 1.04
Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1. PLoS Genet (2012) 1.02
Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development. Cell Mol Life Sci (2012) 1.01
An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation. Proc Natl Acad Sci U S A (2010) 0.99
Notch signaling in cardiac development and disease. Pediatr Cardiol (2009) 0.98
The roles of HLH transcription factors in epithelial mesenchymal transition and multiple molecular mechanisms. Clin Exp Metastasis (2013) 0.97
Target gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressors. PLoS Genet (2012) 0.94
The convergence of Notch and MAPK signaling specifies the blood progenitor fate in the Drosophila mesoderm. Dev Biol (2011) 0.93
Genome-scale study of transcription factor expression in the branching mouse lung. Dev Dyn (2012) 0.91
Isolation, characterization, and molecular regulation of muscle stem cells. Front Physiol (2013) 0.91
Hes1 expression is reduced in Tbx1 null cells and is required for the development of structures affected in 22q11 deletion syndrome. Dev Biol (2010) 0.91
bHLH-Orange Transcription Factors in Development and Cancer. Transl Oncogenomics (2007) 0.89
Repression of androgen receptor activity by HEYL, a third member of the Hairy/Enhancer-of-split-related family of Notch effectors. J Biol Chem (2011) 0.88
Hey bHLH factors in cardiovascular development. Pediatr Cardiol (2009) 0.87
Role of Notch signaling in the mammalian heart. Braz J Med Biol Res (2013) 0.85
HeyL promotes neuronal differentiation of neural progenitor cells. J Neurosci Res (2011) 0.84
Hairy and Enhancer of Split-related with YRPW motif (HEY)2 regulates bone remodeling in mice. J Biol Chem (2013) 0.82
Notch Signaling and the Skeleton. Endocr Rev (2016) 0.82
Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients. Br J Cancer (2013) 0.82
RUNX3 maintains the mesenchymal phenotype after termination of the Notch signal. J Biol Chem (2011) 0.82
NOTCH signaling in Sertoli cells regulates gonocyte fate. Cell Cycle (2013) 0.81
Genomic analysis distinguishes phases of early development of the mouse atrio-ventricular canal. Physiol Genomics (2009) 0.81
Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects. PLoS One (2014) 0.80
The Notch pathway inhibits TGFβ signaling in breast cancer through HEYL-mediated crosstalk. Cancer Res (2014) 0.80
NOTCH1 missense alleles associated with left ventricular outflow tract defects exhibit impaired receptor processing and defective EMT. Biochim Biophys Acta (2010) 0.79
The functional diversity of essential genes required for mammalian cardiac development. Genesis (2014) 0.79
Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA. Nucleic Acids Res (2015) 0.78
Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves. Cardiovasc Res (2015) 0.78
HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage development. J Cell Sci (2016) 0.78
Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol (2015) 0.78
Genetic interaction between pku300 and fbn2b controls endocardial cell proliferation and valve development in zebrafish. J Cell Sci (2013) 0.77
HeyL regulates the number of TrkC neurons in dorsal root ganglia. Dev Biol (2009) 0.77
Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model for Heart Development and Congenital Heart Disease. Stem Cell Rev (2015) 0.76
Hairy and Enhancer of Split-related with YRPW Motif-Like (HeyL) is Dispensable for Bone Remodeling in Mice. J Cell Biochem (2016) 0.75
GATA-dependent transcriptional and epigenetic control of cardiac lineage specification and differentiation. Cell Mol Life Sci (2015) 0.75
Hey, there's a hole in my heart. Circ Res (2007) 0.75
KSHV-Mediated Angiogenesis in Tumor Progression. Viruses (2016) 0.75
Hey bHLH Proteins Interact with a FBXO45 Containing SCF Ubiquitin Ligase Complex and Induce Its Translocation into the Nucleus. PLoS One (2015) 0.75
Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med (2002) 20.68
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature (2009) 18.08
Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J Cell Biol (2003) 7.89
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol (2007) 6.15
New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients. Blood (2007) 5.80
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev (2004) 4.41
Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet (2008) 4.28
IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proc Natl Acad Sci U S A (2007) 3.98
New comprehensive cytogenetic scoring system for primary myelodysplastic syndromes (MDS) and oligoblastic acute myeloid leukemia after MDS derived from an international database merge. J Clin Oncol (2012) 3.88
Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force. J Cell Biol (2013) 3.77
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity (2008) 3.67
Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. J Clin Oncol (2012) 3.59
Collagen-based cell migration models in vitro and in vivo. Semin Cell Dev Biol (2009) 2.84
Controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) for multi-slice imaging. Magn Reson Med (2005) 2.71
SMASH, SENSE, PILS, GRAPPA: how to choose the optimal method. Top Magn Reson Imaging (2004) 2.65
Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways. Immunity (2008) 2.62
Dynamic autocalibrated parallel imaging using temporal GRAPPA (TGRAPPA). Magn Reson Med (2005) 2.62
Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies. Cancer Res (2002) 2.55
Delta-Notch--and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Nucleic Acids Res (2007) 2.51
Cooperative epigenetic modulation by cancer amplicon genes. Cancer Cell (2010) 2.43
Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans. J Clin Invest (2010) 2.42
Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases. Blood (2003) 2.40
Dynamic imaging of cancer growth and invasion: a modified skin-fold chamber model. Histochem Cell Biol (2008) 2.39
Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma. Blood (2011) 2.36
Readily accessible bicyclononynes for bioorthogonal labeling and three-dimensional imaging of living cells. Angew Chem Int Ed Engl (2010) 2.36
General formulation for quantitative G-factor calculation in GRAPPA reconstructions. Magn Reson Med (2009) 2.32
ISG15, an interferon-stimulated ubiquitin-like protein, is not essential for STAT1 signaling and responses against vesicular stomatitis and lymphocytic choriomeningitis virus. Mol Cell Biol (2005) 2.31
Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival. Blood (2009) 2.22
Mechanisms of collective cell migration at a glance. J Cell Sci (2009) 2.15
Sialylation is essential for early development in mice. Proc Natl Acad Sci U S A (2002) 2.15
Monitoring of monocyte recruitment in reperfused myocardial infarction with intramyocardial hemorrhage and microvascular obstruction by combined fluorine 19 and proton cardiac magnetic resonance imaging. Circulation (2013) 2.14
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti. Dev Cell (2009) 2.11
Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells. Nat Genet (2006) 2.10
Controlled aliasing in volumetric parallel imaging (2D CAIPIRINHA). Magn Reson Med (2006) 2.08
A woman who gained weight and became schizophrenic. Lancet (2002) 2.04
Coalesced multicentric analysis of 2,351 patients with myelodysplastic syndromes indicates an underestimation of poor-risk cytogenetics of myelodysplastic syndromes in the international prognostic scoring system. J Clin Oncol (2011) 2.02
Inversion recovery TrueFISP: quantification of T(1), T(2), and spin density. Magn Reson Med (2004) 1.98
Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations. Blood (2012) 1.98
Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS. Nat Neurosci (2011) 1.96
Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas. J Pathol (2011) 1.91
Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney. J Pathol (2012) 1.88
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. Nat Genet (2013) 1.86
Infrared multiphoton microscopy: subcellular-resolved deep tissue imaging. Curr Opin Biotechnol (2009) 1.86
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing. Blood (2013) 1.84
Mapping proteolytic cancer cell-extracellular matrix interfaces. Clin Exp Metastasis (2008) 1.83
Extracellular matrix determinants of proteolytic and non-proteolytic cell migration. Trends Cell Biol (2011) 1.82
Acquired TNFRSF14 mutations in follicular lymphoma are associated with worse prognosis. Cancer Res (2010) 1.79
Direct parallel image reconstructions for spiral trajectories using GRAPPA. Magn Reson Med (2006) 1.78
Control of bone formation by the serpentine receptor Frizzled-9. J Cell Biol (2011) 1.77
Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate. Exp Cell Res (2006) 1.77
Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo. Mol Cell Biol (2007) 1.76
Mouse gridlock: no aortic coarctation or deficiency, but fatal cardiac defects in Hey2 -/- mice. Curr Biol (2002) 1.70
Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors. Development (2006) 1.67
The fibrin-derived peptide Bbeta15-42 protects the myocardium against ischemia-reperfusion injury. Nat Med (2005) 1.66
Field-of-view limitations in parallel imaging. Magn Reson Med (2004) 1.65
The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all-trans retinoic acid in patients with acute myeloid leukemia. Cancer (2006) 1.65
A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia. J Clin Invest (2007) 1.63
Stathmin activity influences sarcoma cell shape, motility, and metastatic potential. Mol Biol Cell (2008) 1.62
Ultrashort echo time imaging using pointwise encoding time reduction with radial acquisition (PETRA). Magn Reson Med (2011) 1.58
Vaccinia virus E3 protein prevents the antiviral action of ISG15. PLoS Pathog (2008) 1.57
A spectrum of biophysical interaction modes between T cells and different antigen-presenting cells during priming in 3-D collagen and in vivo. Blood (2004) 1.54
Genome-wide profiling of follicular lymphoma by array comparative genomic hybridization reveals prognostically significant DNA copy number imbalances. Blood (2008) 1.52
ISG15 regulates peritoneal macrophages functionality against viral infection. PLoS Pathog (2013) 1.51
Molecular mechanisms of cancer cell invasion and plasticity. Br J Dermatol (2006) 1.50
Cancer invasion and resistance: interconnected processes of disease progression and therapy failure. Trends Mol Med (2011) 1.49
Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: a correlative study from the E2496 Intergroup trial. Blood (2012) 1.49
Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of alpha 2B-adrenoceptor deficient mice. Circ Res (2007) 1.48
2D-GRAPPA-operator for faster 3D parallel MRI. Magn Reson Med (2006) 1.48
p53 family members in myogenic differentiation and rhabdomyosarcoma development. Cancer Cell (2006) 1.47
1q gain is a frequent finding in preoperatively treated Wilms tumors, but of limited prognostic value for risk stratification in the SIOP2001/GPOH trial. Genes Chromosomes Cancer (2014) 1.47
Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts. Mol Cell Biol (2005) 1.46
Accelerated volumetric MRI with a SENSE/GRAPPA combination. J Magn Reson Imaging (2006) 1.45
The tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition. Mol Cell Biol (2009) 1.43
Genomic instability of micronucleated cells revealed by single-cell comparative genomic hybridization. Cytometry A (2009) 1.43
Interstitial guidance of cancer invasion. J Pathol (2012) 1.42
IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system. Brain (2011) 1.37
Plasma membrane Ca2+ ATPase 4 is required for sperm motility and male fertility. J Biol Chem (2004) 1.37
Determinants of leader cells in collective cell migration. Integr Biol (Camb) (2010) 1.37
Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS. Blood (2012) 1.36
Gastric hyperplasia in mice with targeted disruption of the carbonic anhydrase gene Car9. Gastroenterology (2002) 1.35
Hey genes in cardiovascular development. Trends Cardiovasc Med (2003) 1.35
Non-Cartesian data reconstruction using GRAPPA operator gridding (GROG). Magn Reson Med (2007) 1.33
FOXO1 is a tumor suppressor in classical Hodgkin lymphoma. Blood (2012) 1.31
Two-photon laser-generated microtracks in 3D collagen lattices: principles of MMP-dependent and -independent collective cancer cell invasion. Phys Biol (2011) 1.30
Gene expression-based model using formalin-fixed paraffin-embedded biopsies predicts overall survival in advanced-stage classical Hodgkin lymphoma. J Clin Oncol (2012) 1.28
Neural response to reward anticipation is modulated by Gray's impulsivity. Neuroimage (2009) 1.27
Genomic rearrangements involving programmed death ligands are recurrent in primary mediastinal large B-cell lymphoma. Blood (2014) 1.26
Results of a phase 2 study of valproic acid alone or in combination with all-trans retinoic acid in 75 patients with myelodysplastic syndrome and relapsed or refractory acute myeloid leukemia. Ann Hematol (2005) 1.26
Integrating neurobiological markers of depression. Arch Gen Psychiatry (2010) 1.24
Invasion of porcine brain microvascular endothelial cells by Streptococcus suis serotype 2. Infect Immun (2004) 1.22
Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila. Dev Dyn (2005) 1.21
IR TrueFISP with a golden-ratio-based radial readout: fast quantification of T1, T2, and proton density. Magn Reson Med (2012) 1.21
Spatial distribution of RF-induced E-fields and implant heating in MRI. Magn Reson Med (2008) 1.20
A regulatory role for CD37 in T cell proliferation. J Immunol (2004) 1.20
Measuring RF-induced currents inside implants: Impact of device configuration on MRI safety of cardiac pacemaker leads. Magn Reson Med (2009) 1.18
Interstitial cell migration: integrin-dependent and alternative adhesion mechanisms. Cell Tissue Res (2009) 1.16
Overlapping expression pattern of the actin organizers Spir-1 and formin-2 in the developing mouse nervous system and the adult brain. Gene Expr Patterns (2004) 1.16
Iron oxide labelling of human mesenchymal stem cells in collagen hydrogels for articular cartilage repair. Biomaterials (2007) 1.16
A brief review of parallel magnetic resonance imaging. Eur Radiol (2003) 1.15
The E3 ubiquitin ligase UBR5 is recurrently mutated in mantle cell lymphoma. Blood (2013) 1.15