Published in J Immunol on March 01, 2004
Targeting of tetraspanin proteins--potential benefits and strategies. Nat Rev Drug Discov (2008) 1.91
A novel Fc-engineered monoclonal antibody to CD37 with enhanced ADCC and high proapoptotic activity for treatment of B-cell malignancies. Blood (2011) 1.87
Characterization of mice lacking the tetraspanin superfamily member CD151. Mol Cell Biol (2004) 1.57
Tetraspanin CD37 directly mediates transduction of survival and apoptotic signals. Cancer Cell (2012) 1.52
Targeting CD37-positive lymphoid malignancies with a novel engineered small modular immunopharmaceutical. Blood (2007) 1.51
Sequential gene profiling of basal cell carcinomas treated with imiquimod in a placebo-controlled study defines the requirements for tissue rejection. Genome Biol (2007) 1.38
The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity. PLoS Pathog (2009) 1.05
Deficiency of the tetraspanin CD63 associated with kidney pathology but normal lysosomal function. Mol Cell Biol (2008) 1.04
Tetraspanin CD151 regulates growth of mammary epithelial cells in three-dimensional extracellular matrix: implication for mammary ductal carcinoma in situ. Cancer Res (2010) 1.03
Tetraspanins as regulators of the tumour microenvironment: implications for metastasis and therapeutic strategies. Br J Pharmacol (2014) 1.01
Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains. Biochem J (2009) 1.00
A conserved tetraspanin subfamily promotes Notch signaling in Caenorhabditis elegans and in human cells. Proc Natl Acad Sci U S A (2010) 0.94
Investigational immunotherapeutics for B-cell malignancies. J Clin Oncol (2010) 0.88
Identification of rat lung--prominent genes by a parallel DNA microarray hybridization. BMC Genomics (2006) 0.86
TSPAN33 is a novel marker of activated and malignant B cells. Clin Immunol (2013) 0.82
Tetraspanin CD37 protects against the development of B cell lymphoma. J Clin Invest (2016) 0.81
The tetraspanin CD37 protects against glomerular IgA deposition and renal pathology. Am J Pathol (2010) 0.81
Tetraspanins as therapeutic targets in hematological malignancy: a concise review. Front Physiol (2015) 0.81
Finding minimum gene subsets with heuristic breadth-first search algorithm for robust tumor classification. BMC Bioinformatics (2012) 0.80
AGS67E, an Anti-CD37 Monomethyl Auristatin E Antibody-Drug Conjugate as a Potential Therapeutic for B/T-Cell Malignancies and AML: A New Role for CD37 in AML. Mol Cancer Ther (2015) 0.79
Screening of genes of proteins interacting with p7 protein of hepatitis C virus from human liver cDNA library by yeast two-hybrid system. World J Gastroenterol (2005) 0.77
RNAseq Analyses Identify Tumor Necrosis Factor-Mediated Inflammation as a Major Abnormality in ALS Spinal Cord. PLoS One (2016) 0.77
Immunization associated with erectile dysfunction based on cross-sectional and genetic analyses. PLoS One (2014) 0.76
Dectin-1-CD37 association regulates IL-6 expression during Toxoplasma gondii infection. Parasitol Res (2014) 0.76
Multispectral imaging reveals the tissue distribution of tetraspanins in human lymphoid organs. Histochem Cell Biol (2015) 0.75
Function and Dynamics of Tetraspanins during Antigen Recognition and Immunological Synapse Formation. Front Immunol (2016) 0.75
Assessment of CD37 B-cell antigen and cell-of-origin significantly improves risk prediction in diffuse large B-cell lymphoma. Blood (2016) 0.75
The Antitumor Activity of IMGN529, a CD37-Targeting Antibody-Drug Conjugate, Is Potentiated by Rituximab in Non-Hodgkin Lymphoma Models. Neoplasia (2017) 0.75
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science (2004) 14.80
Quantitative proteomics reveals subset-specific viral recognition in dendritic cells. Immunity (2010) 4.03
IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proc Natl Acad Sci U S A (2007) 3.98
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity (2008) 3.67
The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur J Immunol (2003) 3.17
Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulus. J Exp Med (2002) 2.94
A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease. Nat Med (2004) 2.93
The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement. Blood (2008) 2.83
TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification. Science (2012) 2.66
Size-dependent immunogenicity: therapeutic and protective properties of nano-vaccines against tumors. J Immunol (2004) 2.33
ISG15, an interferon-stimulated ubiquitin-like protein, is not essential for STAT1 signaling and responses against vesicular stomatitis and lymphocytic choriomeningitis virus. Mol Cell Biol (2005) 2.31
Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E(2) regulates the migratory capacity of specific DC subsets. Blood (2002) 2.30
Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC. J Exp Med (2010) 2.26
Sialylation is essential for early development in mice. Proc Natl Acad Sci U S A (2002) 2.15
Pathogen recognition and development of particulate vaccines: does size matter? Methods (2006) 2.09
CD8alpha+ dendritic cells are required for efficient entry of Listeria monocytogenes into the spleen. Immunity (2006) 2.06
Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition. Circ Res (2007) 2.05
Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways. J Immunol (2005) 2.02
Enhanced CD8 T cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes. Vaccine (2002) 1.97
Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS. Nat Neurosci (2011) 1.96
The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments. Immunity (2012) 1.89
Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice. J Immunol (2003) 1.81
Tetraspanins: molecular organisers of the leukocyte surface. Trends Immunol (2003) 1.79
Control of bone formation by the serpentine receptor Frizzled-9. J Cell Biol (2011) 1.77
Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo. Mol Cell Biol (2007) 1.76
Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection. J Clin Invest (2008) 1.74
Retracted A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control. EMBO J (2005) 1.72
IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling. Nat Commun (2013) 1.71
Mouse gridlock: no aortic coarctation or deficiency, but fatal cardiac defects in Hey2 -/- mice. Curr Biol (2002) 1.70
Dendritic cell precursor populations of mouse blood: identification of the murine homologues of human blood plasmacytoid pre-DC2 and CD11c+ DC1 precursors. Blood (2002) 1.68
The major surface protein of Wolbachia endosymbionts in filarial nematodes elicits immune responses through TLR2 and TLR4. J Immunol (2004) 1.68
Natural regulatory T cells and persistent viral infection. J Virol (2007) 1.62
Vaccinia virus E3 protein prevents the antiviral action of ISG15. PLoS Pathog (2008) 1.57
LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival. Nat Med (2002) 1.57
Syntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulation. Eur J Immunol (2012) 1.57
Production of interferons by dendritic cells, plasmacytoid cells, natural killer cells, and interferon-producing killer dendritic cells. Blood (2006) 1.54
ISG15 regulates peritoneal macrophages functionality against viral infection. PLoS Pathog (2013) 1.51
Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria. PLoS Pathog (2009) 1.46
Signal regulatory protein molecules are differentially expressed by CD8- dendritic cells. J Immunol (2006) 1.37
IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system. Brain (2011) 1.37
Plasma membrane Ca2+ ATPase 4 is required for sperm motility and male fertility. J Biol Chem (2004) 1.37
Gastric hyperplasia in mice with targeted disruption of the carbonic anhydrase gene Car9. Gastroenterology (2002) 1.35
Investigation of a novel approach to scoring Giemsa-stained malaria-infected thin blood films. Malar J (2008) 1.35
IL-2 induces in vivo suppression by CD4(+)CD25(+)Foxp3(+) regulatory T cells. Eur J Immunol (2008) 1.34
Type 1 and 2 immunity following vaccination is influenced by nanoparticle size: formulation of a model vaccine for respiratory syncytial virus. Mol Pharm (2007) 1.34
High salt reduces the activation of IL-4- and IL-13-stimulated macrophages. J Clin Invest (2015) 1.30
Antibodies to Plasmodium falciparum and Plasmodium vivax merozoite surface protein 5 in Indonesia: species-specific and cross-reactive responses. J Infect Dis (2008) 1.28
Pollen-associated phytoprostanes inhibit dendritic cell interleukin-12 production and augment T helper type 2 cell polarization. J Exp Med (2005) 1.27
The C-type lectin Clec12A present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses. J Immunol (2009) 1.25
Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4 CD25 high T cells with susceptibility in Kenyans. PLoS One (2008) 1.25
CpG-DNA aided cross-presentation of soluble antigens by dendritic cells. Eur J Immunol (2002) 1.23
Antigen delivery via two molecules on the CD8- dendritic cell subset induces humoral immunity in the absence of conventional "danger". Eur J Immunol (2005) 1.23
Wound healing is defective in mice lacking tetraspanin CD151. J Invest Dermatol (2006) 1.22
Ex vivo interferon-gamma immune response to thrombospondin-related adhesive protein in coastal Kenyans: longevity and risk of Plasmodium falciparum infection. Am J Trop Med Hyg (2003) 1.22
Adenovirus efficiently transduces plasmacytoid dendritic cells resulting in TLR9-dependent maturation and IFN-alpha production. J Gene Med (2006) 1.21
Cutting edge: Toll-like receptor 9 expression is not required for CpG DNA-aided cross-presentation of DNA-conjugated antigens but essential for cross-priming of CD8 T cells. J Immunol (2003) 1.18
Retracted Reverse signaling through membrane-bound interleukin-15. J Biol Chem (2004) 1.17
Poly-L-lysine-coated nanoparticles: a potent delivery system to enhance DNA vaccine efficacy. Vaccine (2006) 1.16
Retracted Extracellular ATP induces cytokine expression and apoptosis through P2X7 receptor in murine mast cells. J Immunol (2005) 1.16
Retracted Signaling through P2X7 receptor in human T cells involves p56lck, MAP kinases, and transcription factors AP-1 and NF-kappa B. J Biol Chem (2002) 1.15
Plasmodium falciparum-mediated induction of human CD25Foxp3 CD4 T cells is independent of direct TCR stimulation and requires IL-2, IL-10 and TGFbeta. PLoS Pathog (2009) 1.14
The tetraspanin superfamily member CD151 regulates outside-in integrin alphaIIbbeta3 signaling and platelet function. Blood (2004) 1.14
Heroes or villains? T regulatory cells in malaria infection. Trends Parasitol (2009) 1.12
How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: lessons from interleukin-15 (IL-15)/IL-15 receptor alpha. Mol Cell Biol (2008) 1.11
Methods for nano-particle based vaccine formulation and evaluation of their immunogenicity. Methods (2006) 1.11
Mast cell-mediated antigen presentation regulates CD8+ T cell effector functions. Immunity (2009) 1.10
Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion. EMBO J (2002) 1.10
Retracted Soluble Interleukin IL-15Ralpha is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15. J Biol Chem (2007) 1.10
Retracted Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum. Mol Cell Biol (2005) 1.10
Cellular recognition of trimyristoylated peptide or enterobacterial lipopolysaccharide via both TLR2 and TLR4. J Biol Chem (2007) 1.09
Vaccines that facilitate antigen entry into dendritic cells. Immunol Cell Biol (2004) 1.09
Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production. J Immunol (2007) 1.08
M-CSF: a novel plasmacytoid and conventional dendritic cell poietin. Blood (2007) 1.08
SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFNγ. Blood (2011) 1.08
Analysis of FOXP3+ regulatory T cells that display apparent viral antigen specificity during chronic hepatitis C virus infection. PLoS Pathog (2009) 1.08
Differential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b. J Exp Med (2011) 1.07
A glycopeptide in complex with MHC class I uses the GalNAc residue as an anchor. Proc Natl Acad Sci U S A (2003) 1.07
IL-1 beta enhances CD40 ligand-mediated cytokine secretion by human dendritic cells (DC): a mechanism for T cell-independent DC activation. J Immunol (2002) 1.06
IFN-alpha enhances CD40 ligand-mediated activation of immature monocyte-derived dendritic cells. Int Immunol (2002) 1.06
Defining target antigens for CD25+ FOXP3 + IFN-gamma- regulatory T cells in chronic hepatitis C virus infection. Immunol Cell Biol (2007) 1.06
The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity. PLoS Pathog (2009) 1.05
Tetraspanins CD37 and CD151 differentially regulate Ag presentation and T-cell co-stimulation by DC. Eur J Immunol (2009) 1.05
Differential production of inflammatory chemokines by murine dendritic cell subsets. Immunobiology (2004) 1.04
Deficiency of the tetraspanin CD63 associated with kidney pathology but normal lysosomal function. Mol Cell Biol (2008) 1.04
Pilot phase III immunotherapy study in early-stage breast cancer patients using oxidized mannan-MUC1 [ISRCTN71711835]. Breast Cancer Res (2006) 1.03
Mannan derivatives induce phenotypic and functional maturation of mouse dendritic cells. Immunology (2006) 1.03
Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway. J Immunol (2009) 1.03
Mice without the regulator gene Rsc1A1 exhibit increased Na+-D-glucose cotransport in small intestine and develop obesity. Mol Cell Biol (2005) 1.02
Dendritic cells induce immunity and long-lasting protection against blood-stage malaria despite an in vitro parasite-induced maturation defect. Infect Immun (2004) 1.02
Induction of T helper type 1 and 2 responses to 19-kilodalton merozoite surface protein 1 in vaccinated healthy volunteers and adults naturally exposed to malaria. Infect Immun (2002) 1.02
Hierarchy of susceptibility of dendritic cell subsets to infection by Leishmania major: inverse relationship to interleukin-12 production. Infect Immun (2002) 1.02
Retracted Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17). J Biol Chem (2004) 1.01
Cellular reactivity to the p. Falciparum protein trap in adult kenyans: novel epitopes, complex cytokine patterns, and the impact of natural antigenic variation. Am J Trop Med Hyg (2006) 1.00
Hot, sweet and sticky: the glycobiology of Plasmodium falciparum. Trends Parasitol (2008) 0.99