1
|
The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families.
|
PLoS Biol
|
2007
|
13.99
|
2
|
The importance of alignment accuracy for molecular replacement.
|
Acta Crystallogr D Biol Crystallogr
|
2004
|
6.49
|
3
|
Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline.
|
Proc Natl Acad Sci U S A
|
2002
|
6.00
|
4
|
Tolerating some redundancy significantly speeds up clustering of large protein databases.
|
Bioinformatics
|
2002
|
5.46
|
5
|
Three-dimensional structural view of the central metabolic network of Thermotoga maritima.
|
Science
|
2009
|
2.33
|
6
|
XtalPred: a web server for prediction of protein crystallizability.
|
Bioinformatics
|
2007
|
2.26
|
7
|
PSI-2: structural genomics to cover protein domain family space.
|
Structure
|
2009
|
1.92
|
8
|
The challenge of protein structure determination--lessons from structural genomics.
|
Protein Sci
|
2007
|
1.82
|
9
|
The JCSG MR pipeline: optimized alignments, multiple models and parallel searches.
|
Acta Crystallogr D Biol Crystallogr
|
2007
|
1.75
|
10
|
Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R.
|
J Biol Chem
|
2006
|
1.53
|
11
|
Structural genomics is the largest contributor of novel structural leverage.
|
J Struct Funct Genomics
|
2009
|
1.52
|
12
|
Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold.
|
Proteins
|
2006
|
1.51
|
13
|
Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 A resolution.
|
Proteins
|
2002
|
1.45
|
14
|
Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
1.28
|
15
|
Caspases. Regulating death since the origin of life.
|
Plant Physiol
|
2005
|
1.28
|
16
|
Sequence clustering strategies improve remote homology recognitions while reducing search times.
|
Protein Eng
|
2002
|
1.25
|
17
|
Structural basis of murein peptide specificity of a gamma-D-glutamyl-l-diamino acid endopeptidase.
|
Structure
|
2009
|
1.23
|
18
|
Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 A resolution.
|
Proteins
|
2004
|
1.17
|
19
|
Tyrosine phosphorylation of VHR phosphatase by ZAP-70.
|
Nat Immunol
|
2002
|
1.16
|
20
|
Expansion of the protein repertoire in newly explored environments: human gut microbiome specific protein families.
|
PLoS Comput Biol
|
2010
|
1.15
|
21
|
Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution.
|
Proteins
|
2009
|
1.14
|
22
|
Inhibition of T cell antigen receptor signaling by VHR-related MKPX (VHX), a new dual specificity phosphatase related to VH1 related (VHR).
|
J Biol Chem
|
2001
|
1.14
|
23
|
Identification and structural characterization of heme binding in a novel dye-decolorizing peroxidase, TyrA.
|
Proteins
|
2007
|
1.09
|
24
|
Crystal structure of a tandem cystathionine-beta-synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 A resolution.
|
Proteins
|
2004
|
1.09
|
25
|
The structure of the neurotoxin-associated protein HA33/A from Clostridium botulinum suggests a reoccurring beta-trefoil fold in the progenitor toxin complex.
|
J Mol Biol
|
2005
|
1.08
|
26
|
Crystal structures of two novel dye-decolorizing peroxidases reveal a beta-barrel fold with a conserved heme-binding motif.
|
Proteins
|
2007
|
1.04
|
27
|
Structural basis of membrane targeting by the Dock180 family of Rho family guanine exchange factors (Rho-GEFs).
|
J Biol Chem
|
2010
|
1.04
|
28
|
Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 angstrom resolution.
|
Proteins
|
2006
|
1.03
|
29
|
A segment alignment approach to protein comparison.
|
Bioinformatics
|
2003
|
1.03
|
30
|
Structural analysis of papain-like NlpC/P60 superfamily enzymes with a circularly permuted topology reveals potential lipid binding sites.
|
PLoS One
|
2011
|
1.01
|
31
|
Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.
|
J Mol Biol
|
2010
|
1.01
|
32
|
Domain analysis of the tubulin cofactor system: a model for tubulin folding and dimerization.
|
BMC Bioinformatics
|
2003
|
1.01
|
33
|
Crystal structure of an iron-containing 1,3-propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 A resolution.
|
Proteins
|
2004
|
1.00
|
34
|
Crystal structure of the actin binding domain of the cyclase-associated protein.
|
Biochemistry
|
2004
|
1.00
|
35
|
Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 A resolution reveals a new fold.
|
Proteins
|
2005
|
0.99
|
36
|
Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.
|
J Biol Chem
|
2011
|
0.99
|
37
|
Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution.
|
Proteins
|
2008
|
0.99
|
38
|
Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.98
|
39
|
Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga maritima at 2.5 Å resolution.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.95
|
40
|
The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45 Å resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.94
|
41
|
The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.94
|
42
|
Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.5 A resolution.
|
Proteins
|
2004
|
0.92
|
43
|
FFAS-3D: improving fold recognition by including optimized structural features and template re-ranking.
|
Bioinformatics
|
2013
|
0.92
|
44
|
Crystal structure of an alanine-glyoxylate aminotransferase from Anabaena sp. at 1.70 A resolution reveals a noncovalently linked PLP cofactor.
|
Proteins
|
2005
|
0.91
|
45
|
Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.89
|
46
|
Crystal structure of a ribose-5-phosphate isomerase RpiB (TM1080) from Thermotoga maritima at 1.90 A resolution.
|
Proteins
|
2004
|
0.89
|
47
|
Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 A resolution.
|
Proteins
|
2006
|
0.89
|
48
|
Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.89
|
49
|
Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 A resolution.
|
Proteins
|
2004
|
0.89
|
50
|
Crystal structure of a type II quinolic acid phosphoribosyltransferase (TM1645) from Thermotoga maritima at 2.50 A resolution.
|
Proteins
|
2004
|
0.88
|
51
|
Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold.
|
Proteins
|
2006
|
0.88
|
52
|
Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 A resolution reveals a fold similar to the Ran-binding protein Mog1p.
|
Proteins
|
2006
|
0.87
|
53
|
Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution.
|
Proteins
|
2004
|
0.87
|
54
|
A structural basis for the regulatory inactivation of DnaA.
|
J Mol Biol
|
2008
|
0.87
|
55
|
Crystal structure of an HEPN domain protein (TM0613) from Thermotoga maritima at 1.75 A resolution.
|
Proteins
|
2004
|
0.87
|
56
|
Crystal structure of a conserved hypothetical protein (gi: 13879369) from Mouse at 1.90 A resolution reveals a new fold.
|
Proteins
|
2005
|
0.86
|
57
|
Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.86
|
58
|
Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core domain and an auxiliary C-terminal treble-clef zinc finger.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.86
|
59
|
The interplay of fold recognition and experimental structure determination in structural genomics.
|
Curr Opin Struct Biol
|
2004
|
0.85
|
60
|
The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.85
|
61
|
Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 angstroms resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases.
|
Proteins
|
2007
|
0.85
|
62
|
Crystal structure of an indigoidine synthase A (IndA)-like protein (TM1464) from Thermotoga maritima at 1.90 A resolution reveals a new fold.
|
Proteins
|
2005
|
0.85
|
63
|
Crystal structure of homoserine O-succinyltransferase from Bacillus cereus at 2.4 A resolution.
|
Proteins
|
2007
|
0.85
|
64
|
Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution.
|
Proteins
|
2004
|
0.85
|
65
|
Structure of the pilus assembly protein TadZ from Eubacterium rectale: implications for polar localization.
|
Mol Microbiol
|
2012
|
0.85
|
66
|
Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain.
|
J Mol Biol
|
2009
|
0.85
|
67
|
Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 A resolution.
|
Proteins
|
2003
|
0.84
|
68
|
Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 A resolution reveals a new fold.
|
Proteins
|
2006
|
0.84
|
69
|
Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution.
|
Proteins
|
2004
|
0.84
|
70
|
Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution.
|
Proteins
|
2005
|
0.84
|
71
|
Conformational changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas campestris pv. campestris.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.84
|
72
|
A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.84
|
73
|
Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 A resolution.
|
Proteins
|
2008
|
0.83
|
74
|
Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution.
|
Proteins
|
2004
|
0.83
|
75
|
Crystal structure of an Apo mRNA decapping enzyme (DcpS) from Mouse at 1.83 A resolution.
|
Proteins
|
2005
|
0.83
|
76
|
Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids.
|
J Mol Biol
|
2010
|
0.83
|
77
|
Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes.
|
J Biol Chem
|
2009
|
0.83
|
78
|
Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.83
|
79
|
Crystal structure of histidine phosphotransfer protein ShpA, an essential regulator of stalk biogenesis in Caulobacter crescentus.
|
J Mol Biol
|
2009
|
0.83
|
80
|
Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution.
|
Proteins
|
2004
|
0.82
|
81
|
Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 A resolution.
|
Proteins
|
2004
|
0.82
|
82
|
Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution.
|
Proteins
|
2006
|
0.82
|
83
|
Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 A resolution.
|
Proteins
|
2006
|
0.82
|
84
|
Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 A resolution reveals a new fold with a novel active site.
|
Proteins
|
2006
|
0.82
|
85
|
Crystal structure of a putative glutamine amido transferase (TM1158) from Thermotoga maritima at 1.7 A resolution.
|
Proteins
|
2004
|
0.81
|
86
|
Crystal structure of a novel archaeal AAA+ ATPase SSO1545 from Sulfolobus solfataricus.
|
Proteins
|
2009
|
0.81
|
87
|
Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.81
|
88
|
Crystal structure of S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold.
|
Proteins
|
2005
|
0.80
|
89
|
Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.80
|
90
|
Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold.
|
Proteins
|
2008
|
0.80
|
91
|
Structural and sequence analysis of imelysin-like proteins implicated in bacterial iron uptake.
|
PLoS One
|
2011
|
0.80
|
92
|
Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 A resolution.
|
Proteins
|
2006
|
0.80
|
93
|
Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution.
|
Proteins
|
2006
|
0.79
|
94
|
Crystal structure of a zinc-containing glycerol dehydrogenase (TM0423) from Thermotoga maritima at 1.5 A resolution.
|
Proteins
|
2003
|
0.79
|
95
|
Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 A resolution.
|
Proteins
|
2009
|
0.79
|
96
|
Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 angstroms resolution provides a structural basis for bipartite phosphomonoester hydrolysis of 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate.
|
Proteins
|
2007
|
0.79
|
97
|
Structure of an MmyB-like regulator from C. aurantiacus, member of a new transcription factor family linked to antibiotic metabolism in actinomycetes.
|
PLoS One
|
2012
|
0.79
|
98
|
The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.79
|
99
|
Molecular modeling of phosphorylation sites in proteins using a database of local structure segments.
|
J Mol Model
|
2005
|
0.79
|
100
|
The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.78
|
101
|
Crystal structure of TM1030 from Thermotoga maritima at 2.3 A resolution reveals molecular details of its transcription repressor function.
|
Proteins
|
2007
|
0.78
|
102
|
Crystal structure of a phosphoribosylaminoimidazole mutase PurE (TM0446) from Thermotoga maritima at 1.77-A resolution.
|
Proteins
|
2004
|
0.78
|
103
|
Crystal structure of a transcription regulator (TM1602) from Thermotoga maritima at 2.3 A resolution.
|
Proteins
|
2007
|
0.78
|
104
|
The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.78
|
105
|
Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 A resolution.
|
Proteins
|
2004
|
0.77
|
106
|
Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.77
|
107
|
The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.77
|
108
|
Structure of a novel winged-helix like domain from human NFRKB protein.
|
PLoS One
|
2012
|
0.77
|
109
|
Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 A resolution reveals a new fold.
|
Proteins
|
2005
|
0.77
|
110
|
Crystal structure of a putative NADPH-dependent oxidoreductase (GI: 18204011) from mouse at 2.10 A resolution.
|
Proteins
|
2004
|
0.77
|
111
|
Internal organization of large protein families: relationship between the sequence, structure, and function-based clustering.
|
Proteins
|
2011
|
0.77
|
112
|
Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family.
|
Proteins
|
2013
|
0.76
|
113
|
The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu.
|
Protein Sci
|
2010
|
0.76
|
114
|
Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 Å resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.76
|
115
|
Two Pfam protein families characterized by a crystal structure of protein lpg2210 from Legionella pneumophila.
|
BMC Bioinformatics
|
2013
|
0.76
|
116
|
Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.76
|
117
|
Integrated web service for improving alignment quality based on segments comparison.
|
BMC Bioinformatics
|
2004
|
0.76
|
118
|
Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.75
|
119
|
Molecular characterization of novel pyridoxal-5'-phosphate-dependent enzymes from the human microbiome.
|
Protein Sci
|
2014
|
0.75
|
120
|
Crystal structure of a member of a novel family of dioxygenases (PF10014) reveals a conserved cupin fold and active site.
|
Proteins
|
2013
|
0.75
|
121
|
The interplay of SARS-CoV-2 evolution and constraints imposed by the structure and functionality of its proteins.
|
bioRxiv
|
2020
|
0.75
|
122
|
Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 2.4 A resolution.
|
Proteins
|
2004
|
0.75
|
123
|
Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 A resolution reveals a new fold.
|
Proteins
|
2005
|
0.75
|
124
|
Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution.
|
Proteins
|
2008
|
0.75
|
125
|
Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00-A resolution reveals a new fold.
|
Proteins
|
2004
|
0.75
|