Published in Bioorg Med Chem Lett on May 17, 2004
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Preclinical characterization of WAY-211612: a dual 5-HT uptake inhibitor and 5-HT (1A) receptor antagonist and potential novel antidepressant. Br J Pharmacol (2009) 0.76
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
The DNA sequence of the human X chromosome. Nature (2005) 6.97
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci (2004) 4.69
Salivary transcriptome diagnostics for oral cancer detection. Clin Cancer Res (2004) 4.15
Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection. Clin Cancer Res (2009) 3.86
Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology (2002) 3.79
RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS. Neuron (2007) 3.30
Modified Mallampati test, thyromental distance and inter-incisor gap are the best predictors of difficult laryngoscopy in West Africans. Can J Anaesth (2005) 3.22
Salivary proteomic and genomic biomarkers for primary Sjögren's syndrome. Arthritis Rheum (2007) 2.90
Salivary proteomics for oral cancer biomarker discovery. Clin Cancer Res (2008) 2.81
The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions. J Proteome Res (2008) 2.53
Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice. Neurobiol Dis (2008) 2.52
Safety and efficacy of laryngeal mask airway Supreme versus laryngeal mask airway ProSeal: a randomized controlled trial. Eur J Anaesthesiol (2010) 2.42
Human body fluid proteome analysis. Proteomics (2006) 2.39
Large-scale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two-dimensional gel electrophoresis-mass spectrometry. Proteomics (2005) 2.34
Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration. Proc Natl Acad Sci U S A (2013) 2.30
Management choices for the difficult airway by anesthesiologists in Canada. Can J Anaesth (2002) 2.14
Salivary transcriptomic biomarkers for detection of resectable pancreatic cancer. Gastroenterology (2009) 2.13
Nanostructural and transcriptomic analyses of human saliva derived exosomes. PLoS One (2010) 2.11
Transcriptomic dissection of tongue squamous cell carcinoma. BMC Genomics (2008) 2.09
Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics (2009) 2.03
Use of a tracheal tube introducer guide to facilitate difficult intubation with a video laryngoscope. Can J Anaesth (2014) 1.99
The feasibility of measuring renal blood flow using transesophageal echocardiography in patients undergoing cardiac surgery. Anesth Analg (2009) 1.97
Cervical spine overflexion in a halo orthosis contributes to complete upper airway obstruction during awake bronchoscopic intubation: a case report. Can J Anaesth (2014) 1.97
Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. J Proteome Res (2006) 1.96
Characterization of RNA in saliva. Clin Chem (2006) 1.93
Structural determinant of TRPV1 desensitization interacts with calmodulin. Proc Natl Acad Sci U S A (2003) 1.92
Saliva: an emerging biofluid for early detection of diseases. Am J Dent (2009) 1.91
Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency. Nat Genet (2007) 1.87
Mutations of the Wiskott-Aldrich Syndrome Protein (WASP): hotspots, effect on transcription, and translation and phenotype/genotype correlation. Blood (2004) 1.78
Elimination of preoperative testing in ambulatory surgery. Anesth Analg (2009) 1.76
Drosophila fragile X protein, DFXR, regulates neuronal morphology and function in the brain. Neuron (2002) 1.76
Retrospective audit of the air-Q intubating laryngeal airway as a conduit for tracheal intubation in pediatric patients with a difficult airway. Paediatr Anaesth (2010) 1.73
Serum circulating human mRNA profiling and its utility for oral cancer detection. J Clin Oncol (2006) 1.67
Electrochemical sensor for multiplex biomarkers detection. Clin Cancer Res (2009) 1.67
Saliva as a diagnostic tool for periodontal disease: current state and future directions. Periodontol 2000 (2009) 1.66
The FLAMES score accurately predicts mortality risk in burn patients. J Trauma (2008) 1.63
The Effects of Continuous Positive Airway Pressure on Postoperative Outcomes in Obstructive Sleep Apnea Patients Undergoing Surgery: A Systematic Review and Meta-analysis. Anesth Analg (2015) 1.63
Surgical repositioning of dislocated capsular tension rings. Ophthalmology (2005) 1.62
Use of sonography for airway assessment: an observational study. J Ultrasound Med (2010) 1.62
Successful determination of lower inflection point and maximal compliance in a population of patients with acute respiratory distress syndrome. Crit Care Med (2002) 1.60
Late-onset macular degeneration and long anterior lens zonules result from a CTRP5 gene mutation. Invest Ophthalmol Vis Sci (2005) 1.57
Ectopic expression of CGG containing mRNA is neurotoxic in mammals. Hum Mol Genet (2009) 1.54
Systematic comparison of the human saliva and plasma proteomes. Proteomics Clin Appl (2009) 1.51
Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learning. Nat Med (2011) 1.47
Altered leukocyte response to CXCL12 in patients with warts hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome. Blood (2004) 1.46
Subconjunctival lidocaine before laser treatment: a randomized trial. Ophthalmology (2010) 1.46
Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex. Psychopharmacology (Berl) (2002) 1.46
Retinal vein occlusion and traditional risk factors for atherosclerosis. Arch Ophthalmol (2008) 1.44
Global expression-based classification of lymph node metastasis and extracapsular spread of oral tongue squamous cell carcinoma. Neoplasia (2006) 1.44
Salivary diagnostics: enhancing disease detection and making medicine better. Eur J Dent Educ (2008) 1.44
Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer. PLoS One (2010) 1.43
Tracheal extubation with a laryngeal mask airway and exchange catheter in a patient with a difficult airway. Can J Anaesth (2013) 1.42
The difficult airway with recommendations for management--part 2--the anticipated difficult airway. Can J Anaesth (2013) 1.42
Evaluating the cost-effectiveness of anterior uveitis investigation by Canadian ophthalmologists. Can J Ophthalmol (2008) 1.40
Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo. Hum Mol Genet (2004) 1.39
Anesthetic considerations and airway management in a professional singer: case report and brief review. Can J Anaesth (2014) 1.39
Exon-level expression profiling: a comprehensive transcriptome analysis of oral fluids. Clin Chem (2008) 1.38
Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins. Hum Mol Genet (2006) 1.38
Chromosomal microarray analysis (CMA) detects a large X chromosome deletion including FMR1, FMR2, and IDS in a female patient with mental retardation. Am J Med Genet A (2007) 1.37
Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins. J Biol Chem (2005) 1.37
Role for Msh5 in the regulation of Ig class switch recombination. Proc Natl Acad Sci U S A (2007) 1.35
Systemic disease-induced salivary biomarker profiles in mouse models of melanoma and non-small cell lung cancer. PLoS One (2009) 1.35
The clinical value of salivary biomarkers for periodontal disease. Periodontol 2000 (2009) 1.33
AGG interruptions within the maternal FMR1 gene reduce the risk of offspring with fragile X syndrome. Genet Med (2012) 1.33
Interruptions in the expanded ATTCT repeat of spinocerebellar ataxia type 10: repeat purity as a disease modifier? Am J Hum Genet (2005) 1.32
Structural-mechanical characterization of nanoparticle exosomes in human saliva, using correlative AFM, FESEM, and force spectroscopy. ACS Nano (2010) 1.32
Fragile X-related proteins regulate mammalian circadian behavioral rhythms. Am J Hum Genet (2008) 1.32
Use of manometry for laryngeal mask airway reduces postoperative pharyngolaryngeal adverse events: a prospective, randomized trial. Anesthesiology (2010) 1.31
Characterization of salivary RNA by cDNA library analysis. Arch Oral Biol (2006) 1.27
Identification of autoantibody biomarkers for primary Sjögren's syndrome using protein microarrays. Proteomics (2011) 1.27
Pharmacologic characterization of the cloned human trace amine-associated receptor1 (TAAR1) and evidence for species differences with the rat TAAR1. J Pharmacol Exp Ther (2006) 1.26
Haplotype and linkage disequilibrium architecture for human cancer-associated genes. Genome Res (2002) 1.26
Discovery of oral fluid biomarkers for human oral cancer by mass spectrometry. Cancer Genomics Proteomics (2007) 1.25
Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models. J Neurophysiol (2009) 1.24
Bmal1 and β-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced β-cell failure in mice. Mol Cell Biol (2013) 1.22
Bio/abiotic interface constructed from nanoscale DNA dendrimer and conducting polymer for ultrasensitive biomolecular diagnosis. Small (2009) 1.22
Social behavior in Fmr1 knockout mice carrying a human FMR1 transgene. Behav Neurosci (2008) 1.21
Preclinical validation of salivary biomarkers for primary Sjögren's syndrome. Arthritis Care Res (Hoboken) (2010) 1.21
A forward-backward fragment assembling algorithm for the identification of genomic amplification and deletion breakpoints using high-density single nucleotide polymorphism (SNP) array. BMC Bioinformatics (2007) 1.21
Genomic assessments of the frequent loss of heterozygosity region on 8p21.3-p22 in head and neck squamous cell carcinoma. Cancer Genet Cytogenet (2007) 1.19
Positive selection of a pre-expansion CAG repeat of the human SCA2 gene. PLoS Genet (2005) 1.19
Human saliva proteome analysis and disease biomarker discovery. Expert Rev Proteomics (2007) 1.18
Oral squamous cell carcinoma detection by salivary biomarkers in a Serbian population. Oral Oncol (2010) 1.18
Salivary biomarkers for clinical applications. Mol Diagn Ther (2009) 1.17
Saliva Ontology: an ontology-based framework for a Salivaomics Knowledge Base. BMC Bioinformatics (2010) 1.17
DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent manner. EMBO J (2004) 1.17
Evidence for RNA-mediated toxicity in the fragile X-associated tremor/ataxia syndrome. Future Neurol (2009) 1.17
Genomic targets in saliva. Ann N Y Acad Sci (2007) 1.16
Human saliva proteome analysis. Ann N Y Acad Sci (2007) 1.16
RNAprotect saliva: An optimal room- temperature stabilization reagent for the salivary transcriptome. Clin Chem (2006) 1.15
Cyclin G2 dysregulation in human oral cancer. Cancer Res (2004) 1.15
Systems biology analysis of Sjögren's syndrome and mucosa-associated lymphoid tissue lymphoma in parotid glands. Arthritis Rheum (2009) 1.14
Differentially expressed protein markers in human submandibular and sublingual secretions. Int J Oncol (2004) 1.11
Collection, storage, and processing of saliva samples for downstream molecular applications. Methods Mol Biol (2010) 1.10
AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome. Neurobiol Dis (2011) 1.09
Somatic and germline instability of the ATTCT repeat in spinocerebellar ataxia type 10. Am J Hum Genet (2004) 1.08
The difficult airway with recommendations for management--part 1--difficult tracheal intubation encountered in an unconscious/induced patient. Can J Anaesth (2013) 1.08