PubRank

Neil O Carragher

Author PubWeight™ 26.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The role of focal-adhesion kinase in cancer - a new therapeutic opportunity. Nat Rev Cancer 2005 5.57
2 v-Src's hold over actin and cell adhesions. Nat Rev Mol Cell Biol 2002 2.40
3 The calpain system and cancer. Nat Rev Cancer 2011 2.10
4 Inhibition of calpain stabilises podosomes and impairs dendritic cell motility. J Cell Sci 2006 1.47
5 Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53. Cancer Res 2011 1.44
6 Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis. Am J Pathol 2004 1.39
7 Real-time study of E-cadherin and membrane dynamics in living animals: implications for disease modeling and drug development. Cancer Res 2009 1.25
8 Comparison of methods for image-based profiling of cellular morphological responses to small-molecule treatment. J Biomol Screen 2013 1.19
9 High-content phenotypic profiling of drug response signatures across distinct cancer cells. Mol Cancer Ther 2010 1.13
10 AP-1 differentially expressed proteins Krp1 and fibronectin cooperatively enhance Rho-ROCK-independent mesenchymal invasion by altering the function, localization, and activity of nondifferentially expressed proteins. Mol Cell Biol 2006 1.12
11 Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of src in pancreatic cancer. Cancer Res 2013 0.99
12 Development and bioorthogonal activation of palladium-labile prodrugs of gemcitabine. J Med Chem 2014 0.88
13 Dasatinib inhibits mammary tumour development in a genetically engineered mouse model. J Pathol 2013 0.86
14 FLIM-FRET imaging in vivo reveals 3D-environment spatially regulates RhoGTPase activity during cancer cell invasion. Small GTPases 2011 0.84
15 Inhibition of NF-κB signaling ablates the invasive phenotype of glioblastoma. Mol Cancer Res 2013 0.83
16 Live cell in vitro and in vivo imaging applications: accelerating drug discovery. Pharmaceutics 2011 0.79
17 Advanced intravital subcellular imaging reveals vital three-dimensional signalling events driving cancer cell behaviour and drug responses in live tissue. FEBS J 2013 0.77
18 High-content analysis to leverage a robust phenotypic profiling approach to vascular modulation. J Biomol Screen 2013 0.76
19 Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase. J Med Chem 2016 0.75
20 Empirical drug discovery: a view from the proteome. Drug Discov Today Technol 2017 0.75