Published in Nat Neurosci on May 01, 2004
WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res (2005) 12.88
The genome architecture of the Collaborative Cross mouse genetic reference population. Genetics (2012) 3.84
Integrating physical and genetic maps: from genomes to interaction networks. Nat Rev Genet (2007) 2.77
PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits. Nucleic Acids Res (2006) 1.96
Expression quantitative trait loci are highly sensitive to cellular differentiation state. PLoS Genet (2009) 1.92
Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources. Mamm Genome (2007) 1.75
How replicable are mRNA expression QTL? Mamm Genome (2006) 1.71
High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains. Genes Brain Behav (2009) 1.60
Systems genetics of metabolism: the use of the BXD murine reference panel for multiscalar integration of traits. Cell (2012) 1.48
Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice. Mol Vis (2009) 1.44
Extracting gene networks for low-dose radiation using graph theoretical algorithms. PLoS Comput Biol (2006) 1.41
Gene expression differences in mice divergently selected for methamphetamine sensitivity. Mamm Genome (2005) 1.41
Transcriptional signatures of cellular plasticity in mice lacking the alpha1 subunit of GABAA receptors. J Neurosci (2006) 1.35
Cost-effective strategies for completing the interactome. Nat Methods (2008) 1.25
A statistical multiprobe model for analyzing cis and trans genes in genetical genomics experiments with short-oligonucleotide arrays. Genetics (2005) 1.25
Gene expression profiling in the striatum of inbred mouse strains with distinct opioid-related phenotypes. BMC Genomics (2006) 1.20
Intra- and inter-individual genetic differences in gene expression. Mamm Genome (2009) 1.16
Genetic dissection of behavioral flexibility: reversal learning in mice. Biol Psychiatry (2011) 1.12
Genetic modulation of striatal volume by loci on Chrs 6 and 17 in BXD recombinant inbred mice. Genes Brain Behav (2009) 1.10
The genetic control of neocortex volume and covariation with neocortical gene expression in mice. BMC Neurosci (2009) 1.07
Inbred mouse strains C57BL/6J and DBA/2J vary in sensitivity to a subset of bitter stimuli. BMC Genet (2005) 1.06
Weighting by heritability for detection of quantitative trait loci with microarray estimates of gene expression. Genome Biol (2005) 1.05
Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner. BMC Genomics (2012) 1.03
Genetic properties of the MAGIC maize population: a new platform for high definition QTL mapping in Zea mays. Genome Biol (2015) 1.01
Behavioral actions of alcohol: phenotypic relations from multivariate analysis of mutant mouse data. Genes Brain Behav (2012) 1.00
Using gene expression databases for classical trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weight. BMC Genomics (2008) 0.99
Computational, integrative, and comparative methods for the elucidation of genetic coexpression networks. J Biomed Biotechnol (2005) 0.99
A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice. PLoS One (2010) 0.98
A simple method for combining genetic mapping data from multiple crosses and experimental designs. PLoS One (2007) 0.98
Systems genetic analysis of the effects of iron deficiency in mouse brain. Neurogenetics (2012) 0.98
Genome-wide analysis of the mouse lung transcriptome reveals novel molecular gene interaction networks and cell-specific expression signatures. Respir Res (2011) 0.97
Using hippocampal microRNA expression differences between mouse inbred strains to characterise miRNA function. Mamm Genome (2008) 0.97
Congenic dissection of a major QTL for methamphetamine sensitivity implicates epistasis. Genes Brain Behav (2012) 0.97
Genetic networks controlling retinal injury. Mol Vis (2005) 0.97
A major QTL on chromosome 11 influences psychostimulant and opioid sensitivity in mice. Genes Brain Behav (2009) 0.96
Transcriptional profiling of C57 and DBA strains of mice in the absence and presence of morphine. BMC Genomics (2007) 0.95
Design of microarray experiments for genetical genomics studies. Genetics (2006) 0.94
Genome-wide association for fear conditioning in an advanced intercross mouse line. Behav Genet (2012) 0.93
Genome-wide association for methamphetamine sensitivity in an advanced intercross mouse line. Genes Brain Behav (2011) 0.91
Towards systems genetic analyses in barley: Integration of phenotypic, expression and genotype data into GeneNetwork. BMC Genet (2008) 0.91
Integrated gene expression profiling and linkage analysis in the rat. Mamm Genome (2006) 0.90
Using expression genetics to study the neurobiology of ethanol and alcoholism. Int Rev Neurobiol (2010) 0.90
Dissecting genetic networks underlying complex phenotypes: the theoretical framework. PLoS One (2011) 0.90
Combining transcriptional profiling and genetic linkage analysis to uncover gene networks operating in hematopoietic stem cells and their progeny. Immunogenetics (2008) 0.90
Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation. PLoS One (2011) 0.89
Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice. BMC Genomics (2016) 0.88
Anxiety and fear in a cross of C57BL/6J and DBA/2J mice: mapping overlapping and independent QTL for related traits. Genes Brain Behav (2011) 0.88
Quantitative trait loci linked to thalamus and cortex gray matter volumes in BXD recombinant inbred mice. Heredity (Edinb) (2007) 0.87
Accelerating discovery for complex neurological and behavioral disorders through systems genetics and integrative genomics in the laboratory mouse. Neurotherapeutics (2012) 0.86
Genetic and molecular network analysis of behavior. Int Rev Neurobiol (2012) 0.85
Joint mouse-human phenome-wide association to test gene function and disease risk. Nat Commun (2016) 0.85
Genome-wide gene expression profiles in antioxidant pathways and their potential sex differences and connections to vitamin C in mice. Int J Mol Sci (2013) 0.84
Genetic networks in the mouse retina: growth associated protein 43 and phosphatase tensin homolog network. Mol Vis (2011) 0.84
Genetic control of hippocampal neurogenesis. Genome Biol (2006) 0.84
Analyzing gene expression data in mice with the Neuro Behavior Ontology. Mamm Genome (2013) 0.84
Characterization of Genetic Differences within the Centrally Projecting Edinger-Westphal Nucleus of C57BL/6J and DBA/2J Mice by Expression Profiling. Front Neuroanat (2012) 0.84
Measuring behavior of animal models: faults and remedies. Nat Methods (2012) 0.84
Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. Nat Genet (2016) 0.84
Appetitive operant conditioning in mice: heritability and dissociability of training stages. Front Behav Neurosci (2010) 0.83
Genomic loci and candidate genes underlying inflammatory nociception. Pain (2010) 0.83
Peroxisomal L-bifunctional enzyme (Ehhadh) is essential for the production of medium-chain dicarboxylic acids. J Lipid Res (2012) 0.83
Generating embryonic stem cells from the inbred mouse strain DBA/2J, a model of glaucoma and other complex diseases. PLoS One (2012) 0.81
Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics. Genetics (2014) 0.81
Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity. PLoS Genet (2015) 0.81
Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice. Genes Brain Behav (2013) 0.81
Human disease: Strength to strength for mouse models. Nature (2012) 0.80
The Convergence of Systems and Reductionist Approaches in Complex Trait Analysis. Cell (2015) 0.80
Prediction of cis-QTLs in a pair of inbred mouse strains with the use of expression and haplotype data from public databases. Mamm Genome (2006) 0.80
Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease. BMC Genomics (2011) 0.80
Identification of quantitative trait loci and candidate genes for an anxiolytic-like response to ethanol in BXD recombinant inbred strains. Genes Brain Behav (2016) 0.80
Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains. BMC Genomics (2012) 0.79
Genetic control of weight loss during pneumonic Burkholderia pseudomallei infection. Pathog Dis (2014) 0.78
Candidate genes in ocular dominance plasticity. Front Neurosci (2012) 0.78
Identifying gene networks underlying the neurobiology of ethanol and alcoholism. Alcohol Res (2012) 0.78
Anakinra as an interleukin 1 receptor antagonist, complicated genetics and molecular impacts--from the point of view of mouse genomics. Int Immunopharmacol (2012) 0.78
Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse. PLoS Pathog (2016) 0.77
SGDI: system for genomic data integration. Pac Symp Biocomput (2008) 0.77
Using genome-wide expression profiling to define gene networks relevant to the study of complex traits: from RNA integrity to network topology. Int Rev Neurobiol (2012) 0.77
Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test. Genes Brain Behav (2016) 0.76
A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion. Cell Rep (2016) 0.75
Identifying Genomic Regulators of Set-Wise Co-Expression. Proc IEEE Int Symp Bioinformatics Bioeng (2007) 0.75
Alterations in the expression of a neurodevelopmental gene exert long-lasting effects on cognitive-emotional phenotypes and functional brain networks: translational evidence from the stress-resilient Ahi1 knockout mouse. Mol Psychiatry (2016) 0.75
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nat Genet (2005) 10.03
Computational identification of Drosophila microRNA genes. Genome Biol (2003) 9.86
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat Genet (2005) 6.91
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat Immunol (2007) 6.67
The neuroscience information framework: a data and knowledge environment for neuroscience. Neuroinformatics (2008) 4.60
A high-resolution single nucleotide polymorphism genetic map of the mouse genome. PLoS Biol (2006) 4.57
Mitonuclear protein imbalance as a conserved longevity mechanism. Nature (2013) 4.18
WebQTL: web-based complex trait analysis. Neuroinformatics (2003) 4.10
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
A new set of BXD recombinant inbred lines from advanced intercross populations in mice. BMC Genet (2004) 3.74
PONDR-FIT: a meta-predictor of intrinsically disordered amino acids. Biochim Biophys Acta (2010) 3.62
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mamm Genome (2008) 3.52
Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort. Mamm Genome (2002) 3.02
Mapping the genetic architecture of complex traits in experimental populations. Bioinformatics (2007) 2.27
Towards effective and rewarding data sharing. Neuroinformatics (2003) 2.24
Genetic correlates of gene expression in recombinant inbred strains: a relational model system to explore neurobehavioral phenotypes. Neuroinformatics (2003) 2.09
Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice. J Virol (2009) 2.08
Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. J Neurosci (2005) 2.05
The perplexing paradox of paraquat: the case for host-based susceptibility and postulated neurodegenerative effects. J Biochem Mol Toxicol (2014) 2.03
PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits. Nucleic Acids Res (2006) 1.96
Combined expression trait correlations and expression quantitative trait locus mapping. PLoS Genet (2006) 1.93
Unpaired structures in SCA10 (ATTCT)n.(AGAAT)n repeats. J Mol Biol (2003) 1.87
Natural variation and genetic covariance in adult hippocampal neurogenesis. Proc Natl Acad Sci U S A (2006) 1.81
Quantitative trait locus analysis using recombinant inbred intercrosses: theoretical and empirical considerations. Genetics (2005) 1.80
Metabolic networks of longevity. Cell (2010) 1.79
Genetic analysis in the Collaborative Cross breeding population. Genome Res (2011) 1.74
How replicable are mRNA expression QTL? Mamm Genome (2006) 1.71
Dissection of a QTL hotspot on mouse distal chromosome 1 that modulates neurobehavioral phenotypes and gene expression. PLoS Genet (2008) 1.64
Genomic signature and protein sequence analysis of a novel influenza A (H7N9) virus that causes an outbreak in humans in China. Microbes Infect (2013) 1.59
Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits. PLoS One (2012) 1.58
Genetic structure of the LXS panel of recombinant inbred mouse strains: a powerful resource for complex trait analysis. Mamm Genome (2004) 1.53
Strain differences in stress responsivity are associated with divergent amygdala gene expression and glutamate-mediated neuronal excitability. J Neurosci (2010) 1.49
Systems genetics of metabolism: the use of the BXD murine reference panel for multiscalar integration of traits. Cell (2012) 1.48
Integrative genetic analysis of transcription modules: towards filling the gap between genetic loci and inherited traits. Hum Mol Genet (2005) 1.46
Serum bisphenol-A concentration and sex hormone levels in men. Fertil Steril (2013) 1.45
Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice. Mol Vis (2009) 1.44
Variation in mouse basolateral amygdala volume is associated with differences in stress reactivity and fear learning. Neuropsychopharmacology (2008) 1.43
Inferring gene transcriptional modulatory relations: a genetical genomics approach. Hum Mol Genet (2005) 1.43
Identification of a Chr 11 quantitative trait locus that modulates proliferation in the rostral migratory stream of the adult mouse brain. Eur J Neurosci (2010) 1.42
The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection. J Immunol (2007) 1.40
Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes. Proc Natl Acad Sci U S A (2009) 1.38
A strategy for the integration of QTL, gene expression, and sequence analyses. Mamm Genome (2003) 1.38
The Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival. Clin Exp Metastasis (2008) 1.36
Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource. Front Neurosci (2009) 1.36
High frequency of CD4+ CXCR5+ TFH cells in patients with immune-active chronic hepatitis B. PLoS One (2011) 1.36
Informatics center for mouse genomics: the dissection of complex traits of the nervous system. Neuroinformatics (2003) 1.34
Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysis. PLoS One (2008) 1.33
Status and access to the Collaborative Cross population. Mamm Genome (2012) 1.32
Genome-level analysis of genetic regulation of liver gene expression networks. Hepatology (2007) 1.29
Genetic dissection of acute ethanol responsive gene networks in prefrontal cortex: functional and mechanistic implications. PLoS One (2012) 1.29
A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC. J Infect (2012) 1.28
Measurement of refractive state and deprivation myopia in two strains of mice. Optom Vis Sci (2004) 1.27
Increased efficiency of oligonucleotide-mediated gene repair through slowing replication fork progression. Proc Natl Acad Sci U S A (2005) 1.26
Complete chloroplast genome sequence of Magnolia kwangsiensis (Magnoliaceae): implication for DNA barcoding and population genetics. Genome (2011) 1.26
The PhenoGen informatics website: tools for analyses of complex traits. BMC Genet (2007) 1.25