Published in Mol Cell Biol on May 01, 2004
Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nat Genet (2011) 4.02
U2AF1 mutations alter splice site recognition in hematological malignancies. Genome Res (2014) 1.13
Exonic splicing enhancers in fission yeast: functional conservation demonstrates an early evolutionary origin. Genes Dev (2004) 1.02
U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing. Leukemia (2014) 0.91
Molecular characterization and phylogeny of U2AF35 homologs in plants. Plant Physiol (2006) 0.91
A conditional role of U2AF in splicing of introns with unconventional polypyrimidine tracts. Mol Cell Biol (2007) 0.89
Genomic mRNA profiling reveals compensatory mechanisms for the requirement of the essential splicing factor U2AF. Mol Cell Biol (2010) 0.87
Mutations in the Caenorhabditis elegans U2AF large subunit UAF-1 alter the choice of a 3' splice site in vivo. PLoS Genet (2009) 0.87
Analysis of mutant phenotypes and splicing defects demonstrates functional collaboration between the large and small subunits of the essential splicing factor U2AF in vivo. Mol Biol Cell (2004) 0.85
A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit. Genes Dev (2015) 0.82
Dsk1p kinase phosphorylates SR proteins and regulates their cellular localization in fission yeast. Biochem J (2007) 0.82
Factors affecting splicing strength of yeast genes. Comp Funct Genomics (2011) 0.81
New insights into the RNA-based mechanism of action of the anticancer drug 5'-fluorouracil in eukaryotic cells. PLoS One (2013) 0.81
The power of fission: yeast as a tool for understanding complex splicing. Curr Genet (2016) 0.78
Genomic functions of U2AF in constitutive and regulated splicing. RNA Biol (2015) 0.78
Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome Activation. PLoS Genet (2016) 0.76
A dominant role for meiosis-specific 3' RNA processing in controlling expression of a fission yeast cyclin gene. RNA (2012) 0.76
Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons. Nucleic Acids Res (2016) 0.75
RASMOL: biomolecular graphics for all. Trends Biochem Sci (1995) 33.76
Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics (1996) 24.62
The genome sequence of Schizosaccharomyces pombe. Nature (2002) 14.26
Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell (1993) 8.07
Cloning and domain structure of the mammalian splicing factor U2AF. Nature (1992) 6.55
A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly. Cell (1988) 6.16
Systematic mutational analysis of the yeast ACT1 gene. Genetics (1992) 5.02
Comparison of Schizosaccharomyces pombe expression systems. Nucleic Acids Res (1993) 4.65
A three-hybrid system to detect RNA-protein interactions in vivo. Proc Natl Acad Sci U S A (1996) 4.44
Functional recognition of the 3' splice site AG by the splicing factor U2AF35. Nature (1999) 3.72
Optimization of specificity in a cellular protein interaction network by negative selection. Nature (2003) 3.71
The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing. Genes Dev (1996) 3.63
Biochemical characterization of U2 snRNP auxiliary factor: an essential pre-mRNA splicing factor with a novel intranuclear distribution. EMBO J (1991) 3.54
Expressing the human genome. Nature (2001) 3.45
Genome-wide bioinformatic and molecular analysis of introns in Saccharomyces cerevisiae. RNA (1999) 3.40
The yeast MUD2 protein: an interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition. Genes Dev (1994) 3.14
Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG. Nature (1999) 2.87
Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit. Proc Natl Acad Sci U S A (1992) 2.82
Structural basis for recognition of AU-rich element RNA by the HuD protein. Nat Struct Biol (2001) 2.69
Mechanisms of fidelity in pre-mRNA splicing. Curr Opin Cell Biol (2000) 2.66
Both subunits of U2AF recognize the 3' splice site in Caenorhabditis elegans. Nature (1999) 2.65
A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site. Mol Cell Biol (1998) 2.62
Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant Arabidopsis thaliana. Nucleic Acids Res (2002) 2.44
Sucl+ encodes a predicted 13-kilodalton protein that is essential for cell viability and is directly involved in the division cycle of Schizosaccharomyces pombe. Mol Cell Biol (1987) 2.13
Where does fission yeast sit on the tree of life? Genome Biol (2000) 2.09
U2AF homolog required for splicing in vivo. Science (1993) 2.08
A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer. Cell (2001) 2.02
Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP. Mol Cell (2003) 2.00
Phosphorylation regulates in vivo interaction and molecular targeting of serine/arginine-rich pre-mRNA splicing factors. J Cell Biol (1999) 2.00
GLD-3, a bicaudal-C homolog that inhibits FBF to control germline sex determination in C. elegans. Dev Cell (2002) 1.78
The conserved pre-mRNA splicing factor U2AF from Drosophila: requirement for viability. Science (1993) 1.78
The role of U2AF35 and U2AF65 in enhancer-dependent splicing. RNA (2001) 1.76
Pre-messenger RNA processing factors in the Drosophila genome. J Cell Biol (2000) 1.70
Mutations in the small subunit of the Drosophila U2AF splicing factor cause lethality and developmental defects. Proc Natl Acad Sci U S A (1996) 1.60
PUF60: a novel U2AF65-related splicing activity. RNA (1999) 1.59
Pre-mRNA splicing in the absence of an SR protein RS domain. Genes Dev (2000) 1.58
The small subunit of the splicing factor U2AF is conserved in fission yeast. Nucleic Acids Res (1996) 1.48
Ribosomal protein S14 of Saccharomyces cerevisiae regulates its expression by binding to RPS14B pre-mRNA and to 18S rRNA. Mol Cell Biol (1999) 1.46
Metal binding properties and secondary structure of the zinc-binding domain of Nup475. Proc Natl Acad Sci U S A (1996) 1.40
Intron recognition comes of AGe. Nat Struct Biol (2000) 1.38
Evidence for substrate-specific requirement of the splicing factor U2AF(35) and for its function after polypyrimidine tract recognition by U2AF(65). Mol Cell Biol (1999) 1.35
Molecular genetic analysis of the heterodimeric splicing factor U2AF: the RS domain on either the large or small Drosophila subunit is dispensable in vivo. Genes Dev (1998) 1.35
Evidence for splice site pairing via intron definition in Schizosaccharomyces pombe. Mol Cell Biol (2000) 1.34
U2AF35 is encoded by an essential gene clustered in an operon with RRM/cyclophilin in Caenorhabditis elegans. RNA (1999) 1.32
Interaction between subunits of heterodimeric splicing factor U2AF is essential in vivo. Mol Cell Biol (1998) 1.31
Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors. RNA (2003) 1.31
Identification and characterization of srp1, a gene of fission yeast encoding a RNA binding domain and a RS domain typical of SR splicing factors. Nucleic Acids Res (1998) 1.28
Pre-spliceosome formation in S.pombe requires a stable complex of SF1-U2AF(59)-U2AF(23). EMBO J (2002) 1.27
Dual function for U2AF(35) in AG-dependent pre-mRNA splicing. Mol Cell Biol (2001) 1.21
Cloning of Caenorhabditis U2AF65: an alternatively spliced RNA containing a novel exon. Mol Cell Biol (1997) 1.21
The KH domain of the branchpoint sequence binding protein determines specificity for the pre-mRNA branchpoint sequence. RNA (1998) 1.17
Sex-lethal splicing autoregulation in vivo: interactions between SEX-LETHAL, the U1 snRNP and U2AF underlie male exon skipping. Development (2003) 1.17
RNA binding activity of heterodimeric splicing factor U2AF: at least one RS domain is required for high-affinity binding. Mol Cell Biol (1998) 1.15
Srp2, an SR protein family member of fission yeast: in vivo characterization of its modular domains. Nucleic Acids Res (1999) 1.13
Molecular genetic analysis of U2AF59 in Schizosaccharomyces pombe: differential sensitivity of introns to mutational inactivation. RNA (1999) 1.04
U1 small nuclear RNA from Schizosaccharomyces pombe has unique and conserved features and is encoded by an essential single-copy gene. Mol Cell Biol (1990) 1.04
Multiple forms of the U2 small nuclear ribonucleoprotein auxiliary factor U2AF subunits expressed in higher plants. J Biol Chem (1998) 1.02
Schizosaccharomyces pombe zfs1+ encoding a zinc-finger protein functions in the mating pheromone recognition pathway. Mol Biol Cell (1995) 0.99
Solution structures of the first and second RNA-binding domains of human U2 small nuclear ribonucleoprotein particle auxiliary factor (U2AF(65)). EMBO J (1999) 0.97
Unique features of the Trypanosoma cruzi U2AF35 splicing factor. Mol Biochem Parasitol (2003) 0.93
The Srp54 GTPase is essential for protein export in the fission yeast Schizosaccharomyces pombe. Mol Cell Biol (1994) 0.86
Induced folding of the U2AF35 RRM upon binding to U2AF65. FEBS Lett (2002) 0.84
The fission yeast ortholog of the coregulator SKIP interacts with the small subunit of U2AF. Biochem Biophys Res Commun (2001) 0.83
Negative control contributes to an extensive program of meiotic splicing in fission yeast. Mol Cell (2005) 1.44
A complex gene regulatory mechanism that operates at the nexus of multiple RNA processing decisions. Nat Struct Mol Biol (2009) 1.25
Regulation of alternative splicing by local histone modifications: potential roles for RNA-guided mechanisms. Nucleic Acids Res (2013) 1.10
Exonic splicing enhancers in fission yeast: functional conservation demonstrates an early evolutionary origin. Genes Dev (2004) 1.02
A meiotic gene regulatory cascade driven by alternative fates for newly synthesized transcripts. Mol Biol Cell (2010) 0.99
Analysis of mutant phenotypes and splicing defects demonstrates functional collaboration between the large and small subunits of the essential splicing factor U2AF in vivo. Mol Biol Cell (2004) 0.85
Breakthrough articles: putting science first. Nucleic Acids Res (2014) 0.77
A dominant role for meiosis-specific 3' RNA processing in controlling expression of a fission yeast cyclin gene. RNA (2012) 0.76
Measurement of in vivo RNA synthesis rates. Methods Enzymol (2013) 0.75