Published in Cancer Res on May 01, 2004
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Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet (2009) 16.58
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci U S A (2004) 14.59
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell (2008) 12.29
Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet (2007) 10.78
Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell (2009) 10.50
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol (2008) 10.42
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Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas. Genes Dev (2009) 4.43
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Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA. Mol Cell Biol (2006) 3.71
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MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis. PLoS One (2008) 2.82
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MicroRNA MiR-17 retards tissue growth and represses fibronectin expression. Nat Cell Biol (2009) 2.49
miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130. Proc Natl Acad Sci U S A (2008) 2.42
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The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim. Gastroenterology (2009) 2.35
miR-20a encoded by the miR-17-92 cluster increases the metastatic potential of osteosarcoma cells by regulating Fas expression. Cancer Res (2011) 2.06
Germline deletion of the miR-17∼92 cluster causes skeletal and growth defects in humans. Nat Genet (2011) 2.04
miRNA profiling of cancer. Curr Opin Genet Dev (2013) 1.99
EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency. EMBO J (2012) 1.91
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Adult-specific functions of animal microRNAs. Nat Rev Genet (2013) 1.89
Binding of NF-kappaB p65 subunit to the promoter elements is involved in LPS-induced transactivation of miRNA genes in human biliary epithelial cells. Nucleic Acids Res (2010) 1.81
MicroRNAs and their role in progressive kidney diseases. Clin J Am Soc Nephrol (2009) 1.77
miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. Genes Dev (2011) 1.66
The miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescence. Cancer Res (2010) 1.60
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"Myc'ed messages": myc induces transcription of E2F1 while inhibiting its translation via a microRNA polycistron. PLoS Genet (2007) 1.45
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Circular reasoning: microRNAs and cell-cycle control. Trends Biochem Sci (2008) 1.41
Expression profile of microRNAs in c-Myc induced mouse mammary tumors. Breast Cancer Res Treat (2008) 1.41
Alteration of microRNA profiles in squamous cell carcinoma of the head and neck cell lines by human papillomavirus. Head Neck (2011) 1.40
STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA. Genes Dev (2012) 1.38
Array comparative genomic hybridization reveals genomic copy number changes associated with outcome in diffuse large B-cell lymphomas. Blood (2005) 1.37
MicroRNAs of the immune system: roles in inflammation and cancer. Ann N Y Acad Sci (2010) 1.37
Novel classes of non-coding RNAs and cancer. J Transl Med (2012) 1.35
Genomic organization of microRNAs. J Cell Physiol (2010) 1.35
Functional integration of microRNAs into oncogenic and tumor suppressor pathways. Cell Cycle (2008) 1.33
mir-17-92: a polycistronic oncomir with pleiotropic functions. Immunol Rev (2013) 1.32
miRNA response to DNA damage. Trends Biochem Sci (2011) 1.32
Epigenetic silencing of the oncogenic miR-17-92 cluster during PU.1-directed macrophage differentiation. EMBO J (2011) 1.30
microRNA-92a promotes lymph node metastasis of human esophageal squamous cell carcinoma via E-cadherin. J Biol Chem (2010) 1.27
MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice. Blood (2011) 1.26
Prediction and preliminary validation of oncogene regulation by miRNAs. BMC Mol Biol (2007) 1.23
MicroRNA Processing and Human Cancer. J Clin Med (2015) 1.23
Tumorigenicity of the miR-17-92 cluster distilled. Genes Dev (2010) 1.22
Gliomas display a microRNA expression profile reminiscent of neural precursor cells. Neuro Oncol (2010) 1.22
Role of microRNAs in lymphoid biology and disease. Curr Opin Hematol (2011) 1.22
miRNAs as modulators of angiogenesis. Cold Spring Harb Perspect Med (2013) 1.21
miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase. PLoS One (2011) 1.20
Genomic and clinical analysis of amplification of the 13q31 chromosomal region in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group. Clin Cancer Res (2011) 1.19
miRNA Biomarkers in Breast Cancer Detection and Management. J Cancer (2011) 1.18
microRNAs in cardiovascular development. J Mol Cell Cardiol (2012) 1.17
MicroRNAs in cancer treatment and prognosis. Am J Cancer Res (2012) 1.17
Glucocorticoid-mediated repression of the oncogenic microRNA cluster miR-17~92 contributes to the induction of Bim and initiation of apoptosis. Mol Endocrinol (2011) 1.13
MicroRNAs: control and loss of control in human physiology and disease. World J Surg (2009) 1.12
The c-Myc-regulated microRNA-17~92 (miR-17~92) and miR-106a~363 clusters target hCYP19A1 and hGCM1 to inhibit human trophoblast differentiation. Mol Cell Biol (2013) 1.12
Shielding the messenger (RNA): microRNA-based anticancer therapies. Pharmacol Ther (2011) 1.12
Myc overexpression brings out unexpected antiapoptotic effects of miR-34a. Oncogene (2011) 1.11
MicroRNA-17-92 significantly enhances radioresistance in human mantle cell lymphoma cells. Radiat Oncol (2010) 1.10
Upregulation of STAT3 marks Burkitt lymphoma cells refractory to Epstein-Barr virus lytic cycle induction by HDAC inhibitors. J Virol (2009) 1.10
MicroRNAs in autophagy and their emerging roles in crosstalk with apoptosis. Autophagy (2012) 1.10
Feud or Friend? The Role of the miR-17-92 Cluster in Tumorigenesis. Curr Genomics (2010) 1.09
MicroRNAs in B cell development and malignancy. J Hematol Oncol (2012) 1.08
microRNA profiling identifies cancer-specific and prognostic signatures in pediatric malignancies. Clin Cancer Res (2009) 1.08
Role of microRNAs in breast cancer. Cancer Biol Ther (2013) 1.07
B-cell malignancies in microRNA Eμ-miR-17~92 transgenic mice. Proc Natl Acad Sci U S A (2013) 1.06
NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia. J Exp Med (2010) 1.06
Intrinsic expression of host genes and intronic miRNAs in prostate carcinoma cells. Cancer Cell Int (2009) 1.04
MicroRNAs as Molecular Targets for Cancer Therapy: On the Modulation of MicroRNA Expression. Pharmaceuticals (Basel) (2013) 1.04
miR-106b-25/miR-17-92 clusters: polycistrons with oncogenic roles in hepatocellular carcinoma. World J Gastroenterol (2014) 1.03
Noncoding RNA in oncogenesis: a new era of identifying key players. Int J Mol Sci (2013) 1.03
The roles of microRNAs in tumorigenesis and angiogenesis. Int J Physiol Pathophysiol Pharmacol (2010) 1.03
miRNAs in human cancer. Methods Mol Biol (2012) 1.01
Genomic DNA copy-number alterations of the let-7 family in human cancers. PLoS One (2012) 1.01
MicroRNA in pancreatic cancer: pathological, diagnostic and therapeutic implications. Cancer Lett (2009) 1.01
GLO1-A novel amplified gene in human cancer. Genes Chromosomes Cancer (2010) 0.99
Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia. Science (2008) 3.38
MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta. Cancer Res (2010) 2.48
Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma. Blood (2009) 2.43
Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM. Oncogene (2005) 2.36
MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. Blood (2008) 2.29
Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells. Proc Natl Acad Sci U S A (2011) 2.12
TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas. Blood (2009) 1.99
Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma. Cancer Sci (2009) 1.95
Expression profiling using a tumor-specific cDNA microarray predicts the prognosis of intermediate risk neuroblastomas. Cancer Cell (2005) 1.94
Identification of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell neoplasms by genomic and functional analyses. Blood (2011) 1.88
Comparison of genome profiles for identification of distinct subgroups of diffuse large B-cell lymphoma. Blood (2005) 1.78
Enucleation of human erythroblasts involves non-muscle myosin IIB. Blood (2011) 1.76
MicroRNA-150 inhibits tumor invasion and metastasis by targeting the chemokine receptor CCR6, in advanced cutaneous T-cell lymphoma. Blood (2014) 1.76
Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma. Blood (2014) 1.66
Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia. Blood (2009) 1.57
TNFAIP3 is the target gene of chromosome band 6q23.3-q24.1 loss in ocular adnexal marginal zone B cell lymphoma. Genes Chromosomes Cancer (2008) 1.56
Synergistic action of the microRNA-17 polycistron and Myc in aggressive cancer development. Cancer Sci (2007) 1.55
De novo CD5+ diffuse large B-cell lymphoma: a clinicopathologic study of 109 patients. Blood (2002) 1.52
Short report: a major genotype of Japanese encephalitis virus currently circulating in Japan. Am J Trop Med Hyg (2003) 1.51
Genome-wide array-based comparative genomic hybridization of natural killer cell lymphoma/leukemia: different genomic alteration patterns of aggressive NK-cell leukemia and extranodal Nk/T-cell lymphoma, nasal type. Genes Chromosomes Cancer (2005) 1.47
Identification of subtype-specific genomic alterations in aggressive adult T-cell leukemia/lymphoma. Blood (2006) 1.34
CD10-MUM1+ follicular lymphoma lacks BCL2 gene translocation and shows characteristic biologic and clinical features. Blood (2007) 1.28
Kidney-limited intravascular large B cell lymphoma: a distinct variant of IVLBCL? Int J Hematol (2009) 1.26
Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice. Proc Natl Acad Sci U S A (2004) 1.23
Promotion and maintenance of leukemia by ERG. Blood (2011) 1.21
Molecular epidemiological analyses of Japanese encephalitis virus isolates from swine in Japan from 2002 to 2004. J Gen Virol (2007) 1.19
Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1. PLoS Med (2007) 1.19
BMI-1 is highly expressed in M0-subtype acute myeloid leukemia. Int J Hematol (2005) 1.13
Overexpression of miR-210, a downstream target of HIF1α, causes centrosome amplification in renal carcinoma cells. J Pathol (2011) 1.12
Downregulation of SAV1 plays a role in pathogenesis of high-grade clear cell renal cell carcinoma. BMC Cancer (2011) 1.12
Biphasic expression of two paracrine melanogenic cytokines, stem cell factor and endothelin-1, in ultraviolet B-induced human melanogenesis. Am J Pathol (2004) 1.11
Fission yeast Mor2/Cps12, a protein similar to Drosophila Furry, is essential for cell morphogenesis and its mutation induces Wee1-dependent G(2) delay. EMBO J (2002) 1.10
Genomic profiling combined with gene expression profiling in primary central nervous system lymphoma. Blood (2010) 1.06
Clonal evolution of adult T-cell leukemia/lymphoma takes place in the lymph nodes. Blood (2011) 1.05
GPC5 is a possible target for the 13q31-q32 amplification detected in lymphoma cell lines. J Hum Genet (2003) 1.05
Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non-random chromosomal alteration regions including JUN amplification on 1p32. Cancer Sci (2007) 1.03
Genome-wide array-based comparative genomic hybridization of diffuse large B-cell lymphoma: comparison between CD5-positive and CD5-negative cases. Cancer Res (2004) 1.02
Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation. Cancer Res (2013) 1.00
Detection of t(11;18)(q21;q21) in marginal zone lymphoma of mucosa-associated lymphocytic tissue type on paraffin-embedded tissue sections by using fluorescence in situ hybridization. Cancer Genet Cytogenet (2003) 1.00
Involvement of mitogen-activated protein kinase in the cytokine-regulated phosphorylation of transcription factor GATA-1. Hematol J (2004) 1.00
Array comparative genomic hybridization analysis of PTCL-U reveals a distinct subgroup with genetic alterations similar to lymphoma-type adult T-cell leukemia/lymphoma. Clin Cancer Res (2009) 1.00
Genome-wide array-based comparative genomic hybridization of ocular marginal zone B cell lymphoma: comparison with pulmonary and nodal marginal zone B cell lymphoma. Genes Chromosomes Cancer (2007) 1.00
The LRF transcription factor regulates mature B cell development and the germinal center response in mice. J Clin Invest (2011) 0.99
Molecular cytogenetic analysis of the breakpoint region at 6q21-22 in T-cell lymphoma/leukemia cell lines. Genes Chromosomes Cancer (2002) 0.97
Genomic profiling of gastric carcinoma in situ and adenomas by array-based comparative genomic hybridization. J Pathol (2010) 0.97
Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia. J Hum Genet (2010) 0.97
Identification of sources contributing to Mid-Atlantic regional aerosol. J Air Waste Manag Assoc (2002) 0.97
Enteropathy-associated T-cell lymphoma--a clinicopathologic and array comparative genomic hybridization study. Hum Pathol (2010) 0.96
Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma. Am J Hematol (2004) 0.96
Gastric MALT lymphomas are divided into three groups based on responsiveness to Helicobacter Pylori eradication and detection of API2-MALT1 fusion. Am J Surg Pathol (2004) 0.94
Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility. J Hum Genet (2011) 0.93
Fuzzy neural network applied to gene expression profiling for predicting the prognosis of diffuse large B-cell lymphoma. Jpn J Cancer Res (2002) 0.93
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MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10. Blood (2005) 0.93
Clinicopathologic comparison between the API2-MALT1 chimeric transcript-positive and -negative gastric low-grade B-cell lymphoma of mucosa-associated lymphoid tissue type. Jpn J Cancer Res (2002) 0.92
Recent advances in the treatment of adult T-cell leukemia-lymphomas. Cancer Sci (2015) 0.92
Genetic abnormalities involved in t(12;21) TEL-AML1 acute lymphoblastic leukemia: analysis by means of array-based comparative genomic hybridization. Cancer Sci (2007) 0.92
Expansion of functionally defined mouse hematopoietic stem and progenitor cells by a short isoform of RUNX1/AML1. Blood (2011) 0.91
Bortezomib reduces the tumorigenicity of multiple myeloma via downregulation of upregulated targets in clonogenic side population cells. PLoS One (2013) 0.91
Clinical features and prognosis of gastric MALT lymphoma with special reference to responsiveness to H. pylori eradication and API2-MALT1 status. Am J Gastroenterol (2007) 0.91
Identification of CCND3 and BYSL as candidate targets for the 6p21 amplification in diffuse large B-cell lymphoma. Clin Cancer Res (2005) 0.91
Analysis of chromosomal imbalances in de novo CD5-positive diffuse large-B-cell lymphoma detected by comparative genomic hybridization. Genes Chromosomes Cancer (2004) 0.90
TEL (ETV6)-AML1 (RUNX1) initiates self-renewing fetal pro-B cells in association with a transcriptional program shared with embryonic stem cells in mice. Stem Cells (2013) 0.89
Association between obesity and the risk of malignant lymphoma in Japanese: a case-control study. Int J Cancer (2010) 0.89
A biophysical approach to the optimisation of dendritic-tumour cell electrofusion. Biochem Biophys Res Commun (2006) 0.89
Gastric low-grade B-cell MALT lymphoma: treatment, response, and genetic alteration. J Gastroenterol (2003) 0.89
Highly efficient delivery of p16 antitumor peptide into aggressive leukemia/lymphoma cells using a novel transporter system. Mol Cancer Ther (2004) 0.88
Age-associated alteration of γδ T-cell repertoire and different profiles of activation-induced death of Vδ1 and Vδ2 T cells. Int J Hematol (2011) 0.88
Expression profiling analysis of the CD5+ diffuse large B-cell lymphoma subgroup: development of a CD5 signature. Cancer Sci (2006) 0.88
Surveillance of mosquitoes and crows for West Nile virus in the Tokyo metropolitan area. Jpn J Infect Dis (2007) 0.88
Contig array CGH at 3p14.2 points to the FRA3B/FHIT common fragile region as the target gene in diffuse large B-cell lymphoma. Oncogene (2004) 0.87