Published in J Neurosci on May 05, 2004
Mechanisms of neuropathic pain. Neuron (2006) 4.03
Transient receptor potential vanilloid 4-mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury. Circ Res (2006) 2.49
Molecular mechanisms of mechanotransduction in mammalian sensory neurons. Nat Rev Neurosci (2011) 2.12
TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Circ Res (2009) 1.84
Stress induces a switch of intracellular signaling in sensory neurons in a model of generalized pain. J Neurosci (2008) 1.70
Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain Behav Immun (2006) 1.67
Role of interleukin-6 in chronic muscle hyperalgesic priming. Neuroscience (2008) 1.65
Mammalian somatosensory mechanotransduction. Curr Opin Neurobiol (2009) 1.51
TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization. J Neurosci (2009) 1.38
TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation. Mol Pain (2011) 1.38
Activation of urothelial transient receptor potential vanilloid 4 by 4alpha-phorbol 12,13-didecanoate contributes to altered bladder reflexes in the rat. J Pharmacol Exp Ther (2007) 1.30
UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling. Proc Natl Acad Sci U S A (2013) 1.26
Small-fibre neuropathies--advances in diagnosis, pathophysiology and management. Nat Rev Neurol (2012) 1.19
Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation. Proc Natl Acad Sci U S A (2007) 1.13
Development, plasticity and modulation of visceral afferents. Brain Res Rev (2008) 1.11
Hypoosmotic- and pressure-induced membrane stretch activate TRPC5 channels. J Physiol (2008) 1.10
Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism. Proc Natl Acad Sci U S A (2006) 1.10
Molecular and cellular limits to somatosensory specificity. Mol Pain (2008) 1.09
Muscle inflammation induces a protein kinase Cepsilon-dependent chronic-latent muscle pain. J Pain (2008) 1.04
Discovering cytokines as targets for chemotherapy-induced painful peripheral neuropathy. Cytokine (2012) 1.03
5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals. J Neurosci (2012) 1.03
Mechanisms mediating vibration-induced chronic musculoskeletal pain analyzed in the rat. J Pain (2009) 1.01
TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism. Pflugers Arch (2012) 1.01
Marked attenuation of inflammatory mediator-induced C-fiber sensitization for mechanical and hypotonic stimuli in TRPV4-/- mice. Mol Pain (2007) 1.01
Enhanced cytokine-induced mechanical hyperalgesia in skeletal muscle produced by a novel mechanism in rats exposed to unpredictable sound stress. Eur J Pain (2011) 1.00
Modulation of transient receptor potential Vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C. Mol Pain (2009) 0.99
A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation. Br J Pharmacol (2010) 0.99
Pathobiology of cancer chemotherapy-induced peripheral neuropathy (CIPN). Front Pharmacol (2013) 0.99
Neuropathic pain-like alterations in muscle nociceptor function associated with vibration-induced muscle pain. Pain (2010) 0.99
Prevention of paclitaxel-induced allodynia by minocycline: Effect on loss of peripheral nerve fibers and infiltration of macrophages in rats. Mol Pain (2010) 0.97
A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat. Mol Pain (2014) 0.95
Eccentric exercise induces chronic alterations in musculoskeletal nociception in the rat. Eur J Neurosci (2010) 0.95
The emerging role of TRP channels in mechanisms of temperature and pain sensation. Curr Neuropharmacol (2006) 0.93
Changes in osmolality modulate voltage-gated calcium channels in trigeminal ganglion neurons. Brain Res (2008) 0.93
ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1. Curr Neuropharmacol (2008) 0.93
Transient receptor potential ion channels in primary sensory neurons as targets for novel analgesics. Br J Pharmacol (2014) 0.91
Feeling the pressure in mammalian somatosensation. Curr Opin Neurobiol (2005) 0.90
The modulation of voltage-gated potassium channels by anisotonicity in trigeminal ganglion neurons. Neuroscience (2008) 0.90
Osmolality-induced tuning of action potentials in trigeminal ganglion neurons. Neurosci Lett (2009) 0.88
Touch sense: functional organization and molecular determinants of mechanosensitive receptors. Channels (Austin) (2012) 0.87
Human keratinocytes are vanilloid resistant. PLoS One (2008) 0.87
Small molecule vanilloid TRPV1 receptor antagonists approaching drug status: can they live up to the expectations? Naunyn Schmiedebergs Arch Pharmacol (2006) 0.86
Analgesic Effect of Electroacupuncture in a Mouse Fibromyalgia Model: Roles of TRPV1, TRPV4, and pERK. PLoS One (2015) 0.86
Importance of non-selective cation channel TRPV4 interaction with cytoskeleton and their reciprocal regulations in cultured cells. PLoS One (2010) 0.86
ThermoTRPs and Pain. Neuroscientist (2015) 0.86
Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice. J Zhejiang Univ Sci B (2015) 0.85
Changes in osmolality modulate voltage-gated sodium channels in trigeminal ganglion neurons. Neurosci Res (2009) 0.85
Molecular and cellular mechanisms that initiate pain and itch. Cell Mol Life Sci (2015) 0.84
TRP channel cannabinoid receptors in skin sensation, homeostasis, and inflammation. ACS Chem Neurosci (2014) 0.82
Pain in cancer survivors. Br J Pain (2014) 0.81
A TRP to cardiac fibroblast differentiation. Channels (Austin) (2013) 0.81
Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy. Oncogene (2015) 0.81
TRPs and pain. Semin Immunopathol (2015) 0.80
Plasma membrane mechanisms in a preclinical rat model of chronic pain. J Pain (2014) 0.80
Unusual localization and translocation of TRPV4 protein in cultured ventricular myocytes of the neonatal rat. Eur J Histochem (2012) 0.80
Mitochondrial dependence of nerve growth factor-induced mechanical hyperalgesia. Pain (2011) 0.80
TRP Channels in Skin Biology and Pathophysiology. Pharmaceuticals (Basel) (2016) 0.79
Effect of electroacupuncture on rats with chronic constriction injury-induced neuropathic pain. ScientificWorldJournal (2014) 0.79
Abnormal muscle afferent function in a model of Taxol chemotherapy-induced painful neuropathy. J Neurophysiol (2011) 0.78
Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain. Sci Rep (2016) 0.78
P2Y1 Receptor Activation of the TRPV4 Ion Channel Enhances Purinergic Signaling in Satellite Glial Cells. J Biol Chem (2015) 0.77
Identifying the Ion Channels Responsible for Signaling Gastro-Intestinal Based Pain. Pharmaceuticals (Basel) (2010) 0.76
The prophylactic effects of a traditional Japanese medicine, goshajinkigan, on paclitaxel-induced peripheral neuropathy and its mechanism of action. Mol Pain (2014) 0.76
The fundamental unit of pain is the cell. Pain (2013) 0.76
Alcohol and high fat induced chronic pancreatitis: TRPV4 antagonist reduces hypersensitivity. Neuroscience (2015) 0.76
Anthropogenic Radio-Frequency Electromagnetic Fields Elicit Neuropathic Pain in an Amputation Model. PLoS One (2016) 0.75
Chemotherapy-induced peripheral neuropathy. Biomed Rep (2017) 0.75
Modulation of the Activities of Neuronal Ion Channels by Fatty Acid-Derived Pro-Resolvents. Front Physiol (2016) 0.75
4-isopropylcyclohexanol has potential analgesic effects through the inhibition of anoctamin 1, TRPV1 and TRPA1 channel activities. Sci Rep (2017) 0.75
Quantitative Thermal Testing Profiles as a Predictor of Treatment Response to Topical Capsaicin in Patients with Localized Neuropathic Pain. Pain Res Treat (2017) 0.75
Mechanosensor Channels in Mammalian Somatosensory Neurons. Sensors (Basel) (2007) 0.75
TRPV4 ion channel as important cell sensors. J Anesth (2016) 0.75
Signaling pathways in sensitization: toward a nociceptor cell biology. Neuron (2007) 2.70
Epac mediates a cAMP-to-PKC signaling in inflammatory pain: an isolectin B4(+) neuron-specific mechanism. J Neurosci (2005) 2.47
Hypotonicity induces TRPV4-mediated nociception in rat. Neuron (2003) 2.43
Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice. J Physiol (2006) 2.34
Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development? Pharmacol Ther (2006) 2.13
Critical role of nociceptor plasticity in chronic pain. Trends Neurosci (2009) 2.07
Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia. Proc Natl Acad Sci U S A (2002) 1.94
Role of the sensory neuron cytoskeleton in second messenger signaling for inflammatory pain. Neuron (2003) 1.82
A transient receptor potential vanilloid 4-dependent mechanism of hyperalgesia is engaged by concerted action of inflammatory mediators. J Neurosci (2006) 1.71
Stress induces a switch of intracellular signaling in sensory neurons in a model of generalized pain. J Neurosci (2008) 1.70
TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator. Pain (2005) 1.69
Crucial role of neutrophils in the development of mechanical inflammatory hypernociception. J Leukoc Biol (2008) 1.64
Multiple PKCε-dependent mechanisms mediating mechanical hyperalgesia. Pain (2010) 1.55
Neurotoxic catecholamine metabolite in nociceptors contributes to painful peripheral neuropathy. Eur J Neurosci (2008) 1.54
Nucleus accumbens facilitates nociception. Exp Neurol (2011) 1.54
Oxaliplatin acts on IB4-positive nociceptors to induce an oxidative stress-dependent acute painful peripheral neuropathy. J Pain (2008) 1.52
Association between pro- and anti-inflammatory cytokine genes and a symptom cluster of pain, fatigue, sleep disturbance, and depression. Cytokine (2012) 1.52
Tumor necrosis factor receptor type-1 in sensory neurons contributes to induction of chronic enhancement of inflammatory hyperalgesia in rat. Eur J Neurosci (2003) 1.51
Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia. J Neurosci (2008) 1.47
Participation in the decision to become vaccinated against human papillomavirus by California high school girls and the predictors of vaccine status. J Pediatr Health Care (2009) 1.47
Primary afferent nociceptor mechanisms mediating NGF-induced mechanical hyperalgesia. Eur J Neurosci (2005) 1.44
Variations in potassium channel genes are associated with distinct trajectories of persistent breast pain after breast cancer surgery. Pain (2015) 1.40
Caspase signalling in neuropathic and inflammatory pain in the rat. Eur J Neurosci (2004) 1.39
TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization. J Neurosci (2009) 1.38
Burn injury pain: the continuing challenge. J Pain (2007) 1.38
Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat. Pain (2004) 1.28
Comparison of oxaliplatin- and cisplatin-induced painful peripheral neuropathy in the rat. J Pain (2009) 1.28
Proinflammatory cytokines mediating burn-injury pain. Pain (2007) 1.27
Ionic basis of a mechanotransduction current in adult rat dorsal root ganglion neurons. Mol Pain (2006) 1.27
Repeated sound stress enhances inflammatory pain in the rat. Pain (2005) 1.25
GPR30 estrogen receptor agonists induce mechanical hyperalgesia in the rat. Eur J Neurosci (2008) 1.25
GDNF hyperalgesia is mediated by PLCgamma, MAPK/ERK, PI3K, CDK5 and Src family kinase signaling and dependent on the IB4-binding protein versican. Eur J Neurosci (2008) 1.23
Identification of patient subgroups and risk factors for persistent breast pain following breast cancer surgery. J Pain (2012) 1.22
PLC-beta 3 signals upstream of PKC epsilon in acute and chronic inflammatory hyperalgesia. Pain (2007) 1.18
Generation of a pain memory in the primary afferent nociceptor triggered by PKCε activation of CPEB. J Neurosci (2012) 1.15
Integrin signaling in inflammatory and neuropathic pain in the rat. Eur J Neurosci (2004) 1.13
Associations between pro- and anti-inflammatory cytokine genes and breast pain in women prior to breast cancer surgery. J Pain (2012) 1.12
Sound stress-induced long-term enhancement of mechanical hyperalgesia in rats is maintained by sympathoadrenal catecholamines. J Pain (2009) 1.10
Estrogen controls PKCepsilon-dependent mechanical hyperalgesia through direct action on nociceptive neurons. Eur J Neurosci (2006) 1.10
Mitochondrial electron transport in models of neuropathic and inflammatory pain. Pain (2006) 1.08
Primary afferent second messenger cascades interact with specific integrin subunits in producing inflammatory hyperalgesia. Pain (2005) 1.08
Hyperalgesic priming in the rat demonstrates marked sexual dimorphism. Pain (2003) 1.08
Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE2. J Leukoc Biol (2007) 1.06
Further validation of a model of fibromyalgia syndrome in the rat. J Pain (2011) 1.06
Vagal modulation of nociception is mediated by adrenomedullary epinephrine in the rat. Eur J Neurosci (2003) 1.05
Vascular endothelial cells mediate mechanical stimulation-induced enhancement of endothelin hyperalgesia via activation of P2X2/3 receptors on nociceptors. J Neurosci (2013) 1.04
Muscle inflammation induces a protein kinase Cepsilon-dependent chronic-latent muscle pain. J Pain (2008) 1.04
Altered nucleus accumbens circuitry mediates pain-induced antinociception in morphine-tolerant rats. J Neurosci (2002) 1.02
Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18. Brain Behav Immun (2006) 1.02
The fundamental unit of pain is the cell. Pain (2013) 1.01
TrkA and PKC-epsilon in thermal burn-induced mechanical hyperalgesia in the rat. J Pain (2006) 1.01
Mechanisms mediating vibration-induced chronic musculoskeletal pain analyzed in the rat. J Pain (2009) 1.01
Marked attenuation of inflammatory mediator-induced C-fiber sensitization for mechanical and hypotonic stimuli in TRPV4-/- mice. Mol Pain (2007) 1.01
Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: involvement of the NO/cGMP/PKG/KATP signaling pathway. Pain (2010) 1.00
Enhanced cytokine-induced mechanical hyperalgesia in skeletal muscle produced by a novel mechanism in rats exposed to unpredictable sound stress. Eur J Pain (2011) 1.00
Shared mechanisms for opioid tolerance and a transition to chronic pain. J Neurosci (2010) 1.00
Ethanol withdrawal induces hyperalgesia mediated by PKCepsilon. Eur J Neurosci (2006) 1.00
Neuropathic pain-like alterations in muscle nociceptor function associated with vibration-induced muscle pain. Pain (2010) 0.99
Early-life stress produces muscle hyperalgesia and nociceptor sensitization in the adult rat. Pain (2011) 0.98
Teleantagonism: A pharmacodynamic property of the primary nociceptive neuron. Proc Natl Acad Sci U S A (2008) 0.98
Role of nociceptor αCaMKII in transition from acute to chronic pain (hyperalgesic priming) in male and female rats. J Neurosci (2013) 0.98
Role of Drp1, a key mitochondrial fission protein, in neuropathic pain. J Neurosci (2011) 0.98
Alcohol-induced stress in painful alcoholic neuropathy. Eur J Neurosci (2007) 0.98
Interferential therapy produces antinociception during application in various models of inflammatory pain. Phys Ther (2006) 0.98
Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism. Eur J Pharmacol (2007) 0.97
Beta 2-adrenergic receptor regulation of human neutrophil function is sexually dimorphic. Br J Pharmacol (2004) 0.95
Nociceptive effect of subcutaneously injected interleukin-12 is mediated by endothelin (ET) acting on ETB receptors in rats. J Pharmacol Exp Ther (2005) 0.95
Eccentric exercise induces chronic alterations in musculoskeletal nociception in the rat. Eur J Neurosci (2010) 0.95
Peripheral administration of translation inhibitors reverses increased hyperalgesia in a model of chronic pain in the rat. J Pain (2013) 0.95
Hypernociception elicited by tibio-tarsal joint flexion in mice: a novel experimental arthritis model for pharmacological screening. Pharmacol Biochem Behav (2006) 0.95
Neural mechanisms of pain and alcohol dependence. Pharmacol Biochem Behav (2013) 0.93
Opposite nociceptive effects of the arginine/NO/cGMP pathway stimulation in dermal and subcutaneous tissues. Br J Pharmacol (2003) 0.93
mu/delta Cooperativity and opposing kappa-opioid effects in nucleus accumbens-mediated antinociception in the rat. Eur J Neurosci (2002) 0.93
IB4-saporin attenuates acute and eliminates chronic muscle pain in the rat. Exp Neurol (2011) 0.93
TNF-alpha and IL-1beta mediate inflammatory hypernociception in mice triggered by B1 but not B2 kinin receptor. Eur J Pharmacol (2007) 0.93