Published in Pharmacol Ther on May 30, 2006
Nociceptors are interleukin-1beta sensors. J Neurosci (2008) 2.26
IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice. Proc Natl Acad Sci U S A (2008) 1.67
Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway. Proc Natl Acad Sci U S A (2010) 1.34
Commensal microbiota is fundamental for the development of inflammatory pain. Proc Natl Acad Sci U S A (2008) 1.28
Mode of action of cytokines on nociceptive neurons. Exp Brain Res (2009) 1.26
Chronic pain: emerging evidence for the involvement of epigenetics. Neuron (2012) 1.21
Upregulation of IL-6, IL-8 and CCL2 gene expression after acute inflammation: Correlation to clinical pain. Pain (2009) 1.19
The NALP1 inflammasome controls cytokine production and nociception in a rat fracture model of complex regional pain syndrome. Pain (2009) 1.17
Adaptation to chronic hypoxia involves immune cell invasion and increased expression of inflammatory cytokines in rat carotid body. Am J Physiol Lung Cell Mol Physiol (2008) 1.16
The chemokine CXCL1/growth related oncogene increases sodium currents and neuronal excitability in small diameter sensory neurons. Mol Pain (2008) 1.16
The role of enhanced cutaneous IL-1beta signaling in a rat tibia fracture model of complex regional pain syndrome. Pain (2009) 1.15
CXCL5 mediates UVB irradiation-induced pain. Sci Transl Med (2011) 1.15
Associations between pro- and anti-inflammatory cytokine genes and breast pain in women prior to breast cancer surgery. J Pain (2012) 1.12
Chemokine contribution to neuropathic pain: respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons. Pain (2013) 1.10
A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. Life Sci (2010) 1.04
A novel antagonist of the prostaglandin E(2) EP(4) receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models. Br J Pharmacol (2010) 1.01
Nitric oxide synthase modulates CFA-induced thermal hyperalgesia through cytokine regulation in mice. Mol Pain (2010) 1.00
Teleantagonism: A pharmacodynamic property of the primary nociceptive neuron. Proc Natl Acad Sci U S A (2008) 0.98
Treatment with DF 2162, a non-competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory hypernociception in mice. Br J Pharmacol (2008) 0.98
NF-kappaB mediated enhancement of potassium currents by the chemokine CXCL1/growth related oncogene in small diameter rat sensory neurons. Mol Pain (2009) 0.97
Stimulation of peripheral kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kγ/AKT/nNOS/NO signaling pathway. Mol Pain (2012) 0.96
Cancer-induced bone pain: Mechanisms and models. Neurosci Lett (2013) 0.95
Fractalkine mediates inflammatory pain through activation of satellite glial cells. Proc Natl Acad Sci U S A (2013) 0.94
TNFα levels and macrophages expression reflect an inflammatory potential of trigeminal ganglia in a mouse model of familial hemiplegic migraine. PLoS One (2013) 0.93
Antinociceptive activity of ethanol extract from Duguetia chrysocarpa Maas (Annonaceae). ScientificWorldJournal (2012) 0.93
Cot/tpl2 (MAP3K8) mediates myeloperoxidase activity and hypernociception following peripheral inflammation. J Biol Chem (2010) 0.93
Human candidate polymorphisms in sympatric ethnic groups differing in malaria susceptibility in Mali. PLoS One (2013) 0.93
Chronic musculoskeletal pain: review of mechanisms and biochemical biomarkers as assessed by the microdialysis technique. J Pain Res (2014) 0.93
Associations between cytokine genes and a symptom cluster of pain, fatigue, sleep disturbance, and depression in patients prior to breast cancer surgery. Biol Res Nurs (2014) 0.93
Mast cells: versatile gatekeepers of pain. Mol Immunol (2014) 0.91
Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw. PLoS One (2014) 0.90
Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain. Br J Pharmacol (2007) 0.90
Naringenin Inhibits Superoxide Anion-Induced Inflammatory Pain: Role of Oxidative Stress, Cytokines, Nrf-2 and the NO-cGMP-PKG-KATPChannel Signaling Pathway. PLoS One (2016) 0.89
Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists. J Bone Miner Res (2013) 0.89
Targeting endothelin ETA and ETB receptors inhibits antigen-induced neutrophil migration and mechanical hypernociception in mice. Naunyn Schmiedebergs Arch Pharmacol (2008) 0.89
Caspase-1 modulates incisional sensitization and inflammation. Anesthesiology (2010) 0.88
Effects of titanium dioxide nanoparticle exposure on neuroimmune responses in rat airways. J Toxicol Environ Health A (2010) 0.88
Lectin extracted from Canavalia grandiflora seeds presents potential anti-inflammatory and analgesic effects. Naunyn Schmiedebergs Arch Pharmacol (2009) 0.88
Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties. Naunyn Schmiedebergs Arch Pharmacol (2013) 0.87
Genome-wide transcriptional profiling of skin and dorsal root ganglia after ultraviolet-B-induced inflammation. PLoS One (2014) 0.86
Antihypernociceptive activity of anethole in experimental inflammatory pain. Inflammopharmacology (2012) 0.86
Evidence of different mediators of central inflammation in dysfunctional and inflammatory pain--interleukin-8 in fibromyalgia and interleukin-1 β in rheumatoid arthritis. J Neuroimmunol (2015) 0.85
Cytokine candidate genes predict the development of secondary lymphedema following breast cancer surgery. Lymphat Res Biol (2014) 0.85
NOSH-aspirin (NBS-1120), a dual nitric oxide and hydrogen sulfide-releasing hybrid, reduces inflammatory pain. Pharmacol Res Perspect (2015) 0.85
Hepatitis C virus infection is associated with painful symptoms in HIV-infected adults. AIDS Care (2012) 0.85
Cooperative role of tumour necrosis factor-α, interleukin-1β and neutrophils in a novel behavioural model that concomitantly demonstrates articular inflammation and hypernociception in mice. Br J Pharmacol (2011) 0.85
Acute inhibition of signalling phenotype of spinal GABAergic neurons by tumour necrosis factor-alpha. J Physiol (2011) 0.85
Anti-inflammatory and Anti-nociceptive Actions of Systemically or Locally Treated Adipose-Derived Mesenchymal Stem Cells in Experimental Inflammatory Model. Inflammation (2015) 0.83
Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation. Mol Pain (2010) 0.83
Use of Animal Models in Understanding Cancer-induced Bone Pain. Cancer Growth Metastasis (2015) 0.83
Effect of rosmarinic and caffeic acids on inflammatory and nociception process in rats. ISRN Pharmacol (2011) 0.82
Bosentan, a mixed endothelin receptor antagonist, inhibits superoxide anion-induced pain and inflammation in mice. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.82
CD11b+Ly6G- myeloid cells mediate mechanical inflammatory pain hypersensitivity. Proc Natl Acad Sci U S A (2015) 0.82
Persistent changes in spinal cord gene expression after recovery from inflammatory hyperalgesia: a preliminary study on pain memory. BMC Neurosci (2008) 0.82
Regulation of avoidant behaviors and pain by the anti-inflammatory tyrosine phosphatase SHP-1. Neuron Glia Biol (2006) 0.82
How can animal models inform on the transition to chronic symptoms in whiplash? Spine (Phila Pa 1976) (2011) 0.81
The nitroxyl donor, Angeli's salt, inhibits inflammatory hyperalgesia in rats. Neuropharmacology (2013) 0.80
Anti-inflammatory and anti-hyperalgesic effect of all-trans retinoic acid in carrageenan-induced paw edema in Wistar rats: involvement of peroxisome proliferator-activated receptor-β/δ receptors. Indian J Pharmacol (2013) 0.80
Chemokine expression in peripheral tissues from the monosodium iodoacetate model of chronic joint pain. Mol Pain (2013) 0.80
Contact hypersensitivity to oxazolone provokes vulvar mechanical hyperalgesia in mice. PLoS One (2013) 0.80
A cohort study comparing the serum levels of pro- or anti-inflammatory cytokines in patients with lumbar radicular pain and healthy subjects. Eur Spine J (2015) 0.79
IL-4, JAK-STAT signaling, and pain. JAKSTAT (2014) 0.79
Fructose-1,6-bisphosphate reduces inflammatory pain-like behaviour in mice: role of adenosine acting on A1 receptors. Br J Pharmacol (2009) 0.79
Antinociceptive activity of the ethanolic extract, fractions, and aggregatin D isolated from Sinningia aggregata tubers. PLoS One (2015) 0.79
Cytokines as Mediators of Pain-Related Process in Breast Cancer. Mediators Inflamm (2015) 0.79
Collecting and measuring wound exudate biochemical mediators in surgical wounds. J Vis Exp (2012) 0.78
Viral vector-based gene transfer for treatment of chronic pain. Int Anesthesiol Clin (2007) 0.78
Cytokine gene variations associated with subsyndromal depressive symptoms in patients with breast cancer. Eur J Oncol Nurs (2014) 0.78
Quercetin reduces Ehrlich tumor-induced cancer pain in mice. Anal Cell Pathol (Amst) (2015) 0.78
A novel model of inflammatory pain in human skin involving topical application of sodium lauryl sulfate. Inflamm Res (2010) 0.78
Bioactive Fraction of Annona reticulata Bark (or) Ziziphus jujuba Root Bark along with Insulin Attenuates Painful Diabetic Neuropathy through Inhibiting NF-κB Inflammatory Cascade. Front Cell Neurosci (2017) 0.77
TNF-alpha neutralizing antibody blocks thermal sensitivity induced by compound 48/80-provoked mast cell degranulation. F1000Res (2013) 0.77
Quercetin inhibits gout arthritis in mice: induction of an opioid-dependent regulation of inflammasome. Inflammopharmacology (2017) 0.77
Riparin B, a Synthetic Compound Analogue of Riparin, Inhibits the Systemic Inflammatory Response and Oxidative Stress in Mice. Inflammation (2015) 0.77
The ruthenium nitric oxide donor, [Ru(HEDTA)NO], inhibits acute nociception in mice by modulating oxidative stress, cytokine production and activating the cGMP/PKG/ATP-sensitive potassium channel signaling pathway. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.76
The inflammasome as a target for pain therapy. Br J Anaesth (2016) 0.76
Vestibular Mast Cell Density in Vulvodynia: A Case-Controlled Study. J Low Genit Tract Dis (2016) 0.76
Treatment of Cancer Pain by Targeting Cytokines. Mediators Inflamm (2015) 0.76
Atenolol Reduces Leishmania major-Induced Hyperalgesia and TNF-α Without Affecting IL-1β or Keratinocyte Derived Chemokines (KC). Front Pharmacol (2016) 0.76
[Cytokines in psychoneuroendocrine immunological context of nonspecific musculoskeletal pain]. Schmerz (2012) 0.76
Vinpocetine reduces carrageenan-induced inflammatory hyperalgesia in mice by inhibiting oxidative stress, cytokine production and NF-κB activation in the paw and spinal cord. PLoS One (2015) 0.76
H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. Inflammation (2015) 0.76
Nitroxyl inhibits overt pain-like behavior in mice: role of cGMP/PKG/ATP-sensitive potassium channel signaling pathway. Pharmacol Rep (2014) 0.76
Quercetin Inhibits Peripheral and Spinal Cord Nociceptive Mechanisms to Reduce Intense Acute Swimming-Induced Muscle Pain in Mice. PLoS One (2016) 0.75
CXCR1/2 pathways in paclitaxel-induced neuropathic pain. Oncotarget (2017) 0.75
IL-1β-induced modulation of gene expression profile in human dermal fibroblasts: the effects of Thai herbal Sahatsatara formula, piperine and gallic acid possessing antioxidant properties. BMC Complement Altern Med (2017) 0.75
Topical Formulation Containing Naringenin: Efficacy against Ultraviolet B Irradiation-Induced Skin Inflammation and Oxidative Stress in Mice. PLoS One (2016) 0.75
Aryl-1,3,5-triazine ligands of histamine H4 receptor attenuate inflammatory and nociceptive response to carrageen, zymosan and lipopolysaccharide. Inflamm Res (2016) 0.75
Antinoceptive and Anti-inflammatory Activities of the Ethanolic Extract, Fractions and Flavones Isolated from Mimosa tenuiflora (Willd.) Poir (Leguminosae). PLoS One (2016) 0.75
Antinociceptive Effect of Tephrosia sinapou Extract in the Acetic Acid, Phenyl-p-benzoquinone, Formalin, and Complete Freund's Adjuvant Models of Overt Pain-Like Behavior in Mice. Scientifica (Cairo) (2016) 0.75
Nociceptor Sensory Neuron-Immune Interactions in Pain and Inflammation. Trends Immunol (2016) 0.75
Clonal differences in IgE antibodies affect cutaneous anaphylaxis-associated thermal sensitivity in mice. Immunol Lett (2014) 0.75
Whole-body Vibration at Thoracic Resonance Induces Sustained Pain and Widespread Cervical Neuroinflammation in the Rat. Clin Orthop Relat Res (2015) 0.75
The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches. PLoS One (2017) 0.75
Pimaradienoic Acid Inhibits Carrageenan-Induced Inflammatory Leukocyte Recruitment and Edema in Mice: Inhibition of Oxidative Stress, Nitric Oxide and Cytokine Production. PLoS One (2016) 0.75
Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-κB, Caspase-1/11, ASC, NOX, and NOS Isoforms. Inflammation (2016) 0.75
From Inflammation to Current and Alternative Therapies Involved in Wound Healing. Int J Inflam (2017) 0.75
Pyrrolidine dithiocarbamate inhibits superoxide anion-induced pain and inflammation in the paw skin and spinal cord by targeting NF-κB and oxidative stress. Inflammopharmacology (2016) 0.75
Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats. J Neurosci (2003) 2.87
Hypotonicity induces TRPV4-mediated nociception in rat. Neuron (2003) 2.43
Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection. Nat Med (2010) 2.38
Reduction of gap and adherens junction proteins and intercalated disc structural remodeling in the hearts of mice submitted to severe cecal ligation and puncture sepsis. Crit Care Med (2007) 2.29
Infusion of pharmaceutical-grade natural human C-reactive protein is not proinflammatory in healthy adult human volunteers. Circ Res (2013) 2.26
"Cytokine storm" in the phase I trial of monoclonal antibody TGN1412: better understanding the causes to improve preclinical testing of immunotherapeutics. J Immunol (2007) 2.11
Toll-like receptor 4 signaling leads to neutrophil migration impairment in polymicrobial sepsis. Crit Care Med (2006) 2.06
Interleukin-11 attenuates ifosfamide-induced hemorrhagic cystitis. Int Braz J Urol (2007) 2.05
Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia. Brain Behav Immun (2008) 1.92
Transient receptor potential vanilloid 4 is essential in chemotherapy-induced neuropathic pain in the rat. J Neurosci (2004) 1.87
Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis. Proc Natl Acad Sci U S A (2009) 1.86
Essential role of CCR2 in neutrophil tissue infiltration and multiple organ dysfunction in sepsis. Am J Respir Crit Care Med (2010) 1.85
NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout. Arthritis Rheum (2012) 1.83
Failure of neutrophil chemotactic function in septic patients. Crit Care Med (2002) 1.77
IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice. Proc Natl Acad Sci U S A (2008) 1.67
Crucial role of neutrophils in the development of mechanical inflammatory hypernociception. J Leukoc Biol (2008) 1.64
The role of neutrophils in severe sepsis. Shock (2008) 1.64
IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Ann Rheum Dis (2010) 1.62
Protective effects of atorvastatin in rat models of acute pulmonary embolism: involvement of matrix metalloproteinase-9. Crit Care Med (2007) 1.60
Cardiopulmonary resuscitation feedback improves the quality of chest compression provided by hospital health care professionals. Am J Emerg Med (2010) 1.58
Toll-like receptor 9 activation in neutrophils impairs chemotaxis and reduces sepsis outcome. Crit Care Med (2012) 1.53
Bacterial lipopolysaccharide signaling through Toll-like receptor 4 suppresses asthma-like responses via nitric oxide synthase 2 activity. J Immunol (2003) 1.46
Neutrophil paralysis in sepsis. Shock (2010) 1.40
CXCR2-specific chemokines mediate leukotriene B4-dependent recruitment of neutrophils to inflamed joints in mice with antigen-induced arthritis. Arthritis Rheum (2008) 1.39
The viral mimic, polyinosinic:polycytidylic acid, induces fever in rats via an interleukin-1-dependent mechanism. Am J Physiol Regul Integr Comp Physiol (2004) 1.38
ATP-sensitive potassium channel blockage attenuates cisplatin-induced renal damage. Kidney Blood Press Res (2007) 1.38
Role of regulatory T cells in long-term immune dysfunction associated with severe sepsis. Crit Care Med (2010) 1.36
Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway. Proc Natl Acad Sci U S A (2010) 1.34
Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production. Proc Natl Acad Sci U S A (2009) 1.31
IL-17 receptor signaling is required to control polymicrobial sepsis. J Immunol (2009) 1.31
Antinociceptive effects of interleukin-4, -10, and -13 on the writhing response in mice and zymosan-induced knee joint incapacitation in rats. J Pharmacol Exp Ther (2003) 1.30
Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway. Proc Natl Acad Sci U S A (2004) 1.29
IL-18 enhances collagen-induced arthritis by recruiting neutrophils via TNF-alpha and leukotriene B4. J Immunol (2003) 1.26
Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation. Blood (2006) 1.23
MIP-1alpha[CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF-alpha and LTB4. J Leukoc Biol (2005) 1.22
Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain. Am J Physiol Regul Integr Comp Physiol (2006) 1.20
Hydrogen sulfide improves neutrophil migration and survival in sepsis via K+ATP channel activation. Am J Respir Crit Care Med (2010) 1.19
Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury. Br J Pharmacol (2004) 1.19
Dual function of the long pentraxin PTX3 in resistance against pulmonary infection with Klebsiella pneumoniae in transgenic mice. Microbes Infect (2006) 1.15
Tumour necrosis factor-alpha, interleukin-1beta and interleukin-8 induce persistent mechanical nociceptor hypersensitivity. Pain (2002) 1.15
Periodontal pathogens directly promote autoimmune experimental arthritis by inducing a TLR2- and IL-1-driven Th17 response. J Immunol (2014) 1.15
The involvement of CD4+CD25+ T cells in the acute phase of Trypanosoma cruzi infection. Microbes Infect (2008) 1.14
Regulation of type 17 helper T-cell function by nitric oxide during inflammation. Proc Natl Acad Sci U S A (2011) 1.14
Integrin signaling in inflammatory and neuropathic pain in the rat. Eur J Neurosci (2004) 1.13
IL-17 mediates articular hypernociception in antigen-induced arthritis in mice. Pain (2009) 1.13
Safety of biologics, lessons learnt from TGN1412. Curr Opin Biotechnol (2009) 1.12
Peri-sciatic proinflammatory cytokines, reactive oxygen species, and complement induce mirror-image neuropathic pain in rats. Pain (2004) 1.11
The pattern recognition receptors Nod1 and Nod2 account for neutrophil recruitment to the lungs of mice infected with Legionella pneumophila. Microbes Infect (2010) 1.10
Signaling via platelet-activating factor receptors accounts for the impairment of neutrophil migration in polymicrobial sepsis. J Immunol (2006) 1.09
Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain. Br J Pharmacol (2004) 1.09
How predictive are in vitro assays for cytokine release syndrome in vivo? A comparison of methods reveals worrying differences in sensitivity and frequency of response. Cytokine (2013) 1.08
Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection. Proc Natl Acad Sci U S A (2009) 1.08
Hyperalgesic priming in the rat demonstrates marked sexual dimorphism. Pain (2003) 1.08
Interleukin-6 in combination with its soluble IL-6 receptor sensitises rat skin nociceptors to heat, in vivo. Pain (2002) 1.08
Cytokine-induced neutrophil chemoattractant 1 (CINC-1) mediates the sympathetic component of inflammatory mechanical hypersensitivitiy in rats. Eur Cytokine Netw (2003) 1.07
Interleukin-6 and leptin mediate lipopolysaccharide-induced fever and sickness behavior. Physiol Behav (2006) 1.07
High serum nitric oxide levels in patients with severe leptospirosis. Acta Trop (2007) 1.06
Peripheral hyperalgesic cytokines. Adv Exp Med Biol (2003) 1.06
Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE2. J Leukoc Biol (2007) 1.06
IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production. Eur J Immunol (2007) 1.06
Nitric oxide inhibits neutrophil migration by a mechanism dependent on ICAM-1: role of soluble guanylate cyclase. Nitric Oxide (2006) 1.04
Phlebotomine salivas inhibit immune inflammation-induced neutrophil migration via an autocrine DC-derived PGE2/IL-10 sequential pathway. J Leukoc Biol (2008) 1.04
The essential role of IFN-gamma in the control of lethal Aggregatibacter actinomycetemcomitans infection in mice. Microbes Infect (2008) 1.03
Interleukin-6 mediates low-threshold mechanical allodynia induced by intrathecal HIV-1 envelope glycoprotein gp120. Brain Behav Immun (2007) 1.02
Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18. Brain Behav Immun (2006) 1.02
The role of Nox2-derived ROS in the development of cognitive impairment after sepsis. J Neuroinflammation (2014) 1.01
Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain. J Neurosci (2009) 1.01
Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: involvement of the NO/cGMP/PKG/KATP signaling pathway. Pain (2010) 1.00
Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency. Hum Mol Genet (2009) 1.00