Yukiko Gotoh

Author PubWeight™ 60.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Akt enhances Mdm2-mediated ubiquitination and degradation of p53. J Biol Chem 2002 3.01
2 The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development 2004 2.94
3 Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nat Cell Biol 2004 2.75
4 JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins. EMBO J 2004 2.50
5 Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition. Neuron 2009 2.16
6 Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions. J Biol Chem 2003 2.12
7 SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling. Nature 2002 2.08
8 Retracted Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade. Nat Cell Biol 2003 2.08
9 JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3. J Cell Biol 2005 2.06
10 Scaffolding function of PAK in the PDK1-Akt pathway. Nat Cell Biol 2008 2.02
11 Epigenetic control of neural precursor cell fate during development. Nat Rev Neurosci 2010 1.93
12 The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria. J Biol Chem 2002 1.60
13 Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone. Stem Cells 2007 1.53
14 Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes. Mol Endocrinol 2002 1.35
15 Differing roles of Akt and serum- and glucocorticoid-regulated kinase in glucose metabolism, DNA synthesis, and oncogenic activity. J Biol Chem 2003 1.25
16 Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex. Development 2006 1.24
17 Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis. Dev Biol 2004 1.23
18 Activation of the c-Jun N-terminal kinase pathway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis. Mol Cell Biol 2007 1.19
19 The PI3K-Akt pathway promotes microtubule stabilization in migrating fibroblasts. Genes Cells 2007 1.17
20 Stage-dependent fate determination of neural precursor cells in mouse forebrain. Neurosci Res 2005 1.17
21 The cyclin-dependent kinase inhibitors p57 and p27 regulate neuronal migration in the developing mouse neocortex. J Biol Chem 2006 1.16
22 Akt-PDK1 complex mediates epidermal growth factor-induced membrane protrusion through Ral activation. Mol Biol Cell 2006 1.15
23 Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex. Development 2010 1.13
24 Regulation of the cell surface expression of human BCRP/ABCG2 by the phosphorylation state of Akt in polarized cells. Drug Metab Dispos 2005 1.13
25 The Sox-2 regulatory regions display their activities in two distinct types of multipotent stem cells. Mol Cell Biol 2004 1.13
26 Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalon. Development 2008 1.07
27 HMGA regulates the global chromatin state and neurogenic potential in neocortical precursor cells. Nat Neurosci 2012 1.06
28 Mechanisms that regulate the number of neurons during mouse neocortical development. Curr Opin Neurobiol 2010 1.01
29 α2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2. Nat Neurosci 2011 1.00
30 Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism. Nat Neurosci 2013 0.99
31 Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1. Proc Natl Acad Sci U S A 2009 0.98
32 A noncoding RNA regulates the neurogenin1 gene locus during mouse neocortical development. Proc Natl Acad Sci U S A 2012 0.98
33 Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis. Nat Commun 2013 0.96
34 p57 controls adult neural stem cell quiescence and modulates the pace of lifelong neurogenesis. EMBO J 2013 0.90
35 Adenosine A2A receptor facilitates calcium-dependent protein secretion through the activation of protein kinase A and phosphatidylinositol-3 kinase in PC12 cells. Cell Struct Funct 2004 0.88
36 Akt1 promotes focal adhesion disassembly and cell motility through phosphorylation of FAK in growth factor-stimulated cells. J Cell Sci 2012 0.87
37 The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells. Genes Cells 2003 0.86
38 Epidermal growth factor signaling mediated by grb2 associated binder1 is required for the spatiotemporally regulated proliferation of olig2-expressing progenitors in the embryonic spinal cord. Stem Cells 2007 0.81
39 Transcriptional coupling of neuronal fate commitment and the onset of migration. Curr Opin Neurobiol 2013 0.79
40 JNK phosphorylates synaptotagmin-4 and enhances Ca2+-evoked release. EMBO J 2007 0.79
41 High mobility group nucleosome-binding family proteins promote astrocyte differentiation of neural precursor cells. Stem Cells 2014 0.78
42 Transcriptional activation of mouse major satellite regions during neuronal differentiation. Cell Struct Funct 2012 0.78
43 IMP2 regulates differentiation potentials of mouse neocortical neural precursor cells. Genes Cells 2013 0.77
44 Up-regulation of HP1γ expression during neuronal maturation promotes axonal and dendritic development in mouse embryonic neocortex. Genes Cells 2014 0.77
45 PDK1 regulates the generation of oligodendrocyte precursor cells at an early stage of mouse telencephalic development. Genes Cells 2012 0.76
46 Mitochondrial localization of the antiviral signaling adaptor IPS-1 is important for its induction of caspase activation. Genes Cells 2013 0.76
47 [Role of the JNK signaling pathway]. Tanpakushitsu Kakusan Koso 2008 0.75