Published in Neuron on September 10, 2009
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TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration. Cell Stem Cell (2010) 2.89
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The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation. EMBO J (2013) 0.94
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Ring1b bookmarks genes in pancreatic embryonic progenitors for repression in adult β cells. Genes Dev (2012) 0.91
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NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development. J Neurosci (2014) 0.87
Dynamic patterns of histone lysine methylation in the developing retina. Invest Ophthalmol Vis Sci (2010) 0.86
MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression. J Biol Chem (2014) 0.85
Molecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical Development. Front Neurosci (2015) 0.84
Zrf1 is required to establish and maintain neural progenitor identity. Genes Dev (2014) 0.84
Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells. Proc Natl Acad Sci U S A (2014) 0.84
H2AK119Ub1 and H3K27Me3 in molecular staging for survival prediction of patients with pancreatic ductal adenocarcinoma. Oncotarget (2014) 0.84
The Neurogenic Potential of Astrocytes Is Regulated by Inflammatory Signals. Mol Neurobiol (2015) 0.84
Polycomb repressive complex PRC2 regulates Xenopus retina development downstream of Wnt/β-catenin signaling. Development (2013) 0.83
Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation. Dev Biol (2015) 0.83
Polycomb repressive complex 1 activities determine the columnar organization of motor neurons. Genes Dev (2012) 0.82
Proliferation control in neural stem and progenitor cells. Nat Rev Neurosci (2015) 0.82
Roles of repressive epigenetic machinery in lineage decision of T cells. Immunology (2013) 0.81
Tcf3 represses Wnt-β-catenin signaling and maintains neural stem cell population during neocortical development. PLoS One (2014) 0.81
Impaired neural differentiation of induced pluripotent stem cells generated from a mouse model of Sandhoff disease. PLoS One (2013) 0.81
Polycomb group protein Ezh2 regulates hepatic progenitor cell proliferation and differentiation in murine embryonic liver. PLoS One (2014) 0.80
The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival. Mol Cell Neurosci (2014) 0.79
GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors. PLoS One (2012) 0.79
The Role of Epigenetic Mechanisms in the Regulation of Gene Expression in the Nervous System. J Neurosci (2016) 0.78
EGFR promoter exhibits dynamic histone modifications and binding of ASH2L and P300 in human germinal matrix and gliomas. Epigenetics (2015) 0.78
Epigenetic regulation of retinal development and disease. J Ocul Biol Dis Infor (2012) 0.78
Epigenetic modifications and long noncoding RNAs influence pancreas development and function. Trends Genet (2015) 0.78
Epigenetic mechanisms in neurogenesis. Nat Rev Neurosci (2016) 0.78
Loss of EZH2 results in precocious mammary gland development and activation of STAT5-dependent genes. Nucleic Acids Res (2015) 0.78
Switching modes in corticogenesis: mechanisms of neuronal subtype transitions and integration in the cerebral cortex. Front Neurosci (2015) 0.78
EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21. Open Biol (2016) 0.78
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Characterization of Np95 expression in mouse brain from embryo to adult: A novel marker for proliferating neural stem/precursor cells. Neurogenesis (Austin) (2014) 0.77
Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation. Plant Cell (2016) 0.77
MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells. Stem Cell Reports (2015) 0.77
The roles and regulation of Polycomb complexes in neural development. Cell Tissue Res (2014) 0.77
Epigenetics, nervous system tumors, and cancer stem cells. Cancers (Basel) (2011) 0.77
Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain. Neural Plast (2016) 0.76
The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children. J Neurooncol (2017) 0.76
Polycomb controls gliogenesis by regulating the transient expression of the Gcm/Glide fate determinant. PLoS Genet (2012) 0.76
Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation. BMC Biol (2015) 0.76
Polycomb Ezh2 controls the fate of GABAergic neurons in the embryonic cerebellum. Development (2016) 0.76
Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis. J Exp Med (2016) 0.75
Mechanisms of temporal identity regulation in mouse retinal progenitor cells. Neurogenesis (Austin) (2015) 0.75
Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signalling. Nat Commun (2016) 0.75
Ezh2 is involved in radial neuronal migration through regulating Reelin expression in cerebral cortex. Sci Rep (2015) 0.75
Integrin-associated protein promotes neuronal differentiation of neural stem/progenitor cells. PLoS One (2015) 0.75
EZH2 regulates spinal neuroinflammation in rats with neuropathic pain. Neuroscience (2017) 0.75
Spatial Interplay between Polycomb and Trithorax Complexes Controls Transcriptional Activity in T Lymphocytes. Mol Cell Biol (2015) 0.75
The morphogen Decapentaplegic employs a two-tier mechanism to activate target retinal determining genes during ectopic eye formation in Drosophila. Sci Rep (2016) 0.75
Association of new deletion/duplication region at chromosome 1p21 with intellectual disability, severe speech deficit and autism spectrum disorder-like behavior: an all-in approach to solving the DPYD enigma. Transl Neurosci (2015) 0.75
Forebrain neurogenesis: From embryo to adult. Trends Dev Biol (2016) 0.75
Mechanisms of cellular plasticity in cerebral perivascular region. Prog Brain Res (2016) 0.75
The loss of Ezh2 drives the pathogenesis of myelofibrosis and sensitizes tumor-initiating cells to bromodomain inhibition. J Exp Med (2016) 0.75
Unlocking the Neurogenic Potential of Mammalian Müller Glia. Int J Stem Cells (2016) 0.75
Impact of lipid nutrition on neural stem/progenitor cells. Stem Cells Int (2013) 0.75
Only scratching the cell surface: extracellular signals in cerebrum development. Curr Opin Genet Dev (2013) 0.75
EZH2 orchestrates apicobasal polarity and neuroepithelial cell renewal. Neurogenesis (Austin) (2016) 0.75
Neurogenic to Gliogenic Fate Transition Perturbed by Loss of HMGB2. Front Mol Neurosci (2017) 0.75
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Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature (2006) 25.90
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet (2008) 11.17
Role of histone H2A ubiquitination in Polycomb silencing. Nature (2004) 9.48
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature (2007) 8.17
Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells. Nat Cell Biol (2007) 6.30
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Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev Cell (2004) 5.72
Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing. EMBO J (2006) 4.16
The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors. Nat Immunol (2007) 4.12
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity (2004) 3.25
Akt enhances Mdm2-mediated ubiquitination and degradation of p53. J Biol Chem (2002) 3.01
The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development (2004) 2.94
Arabidopsis transcriptome analysis under drought, cold, high-salinity and ABA treatment conditions using a tiling array. Plant Cell Physiol (2008) 2.84
RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3. Cell (2012) 2.77
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nat Cell Biol (2004) 2.75
Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor. Mol Cell Proteomics (2007) 2.63
Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity. Development (2008) 2.53
JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins. EMBO J (2004) 2.50
SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes. Blood (2012) 2.50
Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function. EMBO J (2002) 2.49
Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1. Nat Med (2002) 2.45
A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination. Genesis (2004) 2.40
PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos. Nat Genet (2008) 2.37
Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks. J Clin Invest (2010) 2.29
In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses. J Exp Med (2005) 2.28
Genome-wide analysis of alternative pre-mRNA splicing in Arabidopsis thaliana based on full-length cDNA sequences. Nucleic Acids Res (2004) 2.19
Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions. J Biol Chem (2003) 2.12
SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling. Nature (2002) 2.08
Retracted Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade. Nat Cell Biol (2003) 2.08
Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice. PLoS Genet (2006) 2.07
JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3. J Cell Biol (2005) 2.06
Scaffolding function of PAK in the PDK1-Akt pathway. Nat Cell Biol (2008) 2.02
CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis. Cancer Cell (2011) 2.01
Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation. Cell Stem Cell (2013) 2.01
KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands. Elife (2012) 1.99
Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus. EMBO J (2007) 1.99
ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency. Cell Stem Cell (2010) 1.98
Novel regulation of MHC class II function in B cells. EMBO J (2007) 1.98
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Large-scale comparative phosphoproteomics identifies conserved phosphorylation sites in plants. Plant Physiol (2010) 1.93
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Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources. Mamm Genome (2007) 1.75
Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells. Bioinformatics (2007) 1.73
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Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells. Blood (2011) 1.66
PRC1 coordinates timing of sexual differentiation of female primordial germ cells. Nature (2013) 1.65
UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9. Nat Commun (2013) 1.61
Angiopoietin-related growth factor antagonizes obesity and insulin resistance. Nat Med (2005) 1.61
The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria. J Biol Chem (2002) 1.60
Genome-wide suppression of aberrant mRNA-like noncoding RNAs by NMD in Arabidopsis. Proc Natl Acad Sci U S A (2009) 1.60
CCN3 inhibits neointimal hyperplasia through modulation of smooth muscle cell growth and migration. Arterioscler Thromb Vasc Biol (2010) 1.60
MASCP Gator: an aggregation portal for the visualization of Arabidopsis proteomics data. Plant Physiol (2010) 1.59
Gateways to the FANTOM5 promoter level mammalian expression atlas. Genome Biol (2015) 1.58
CRTAM confers late-stage activation of CD8+ T cells to regulate retention within lymph node. J Immunol (2009) 1.57
Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia. Blood (2012) 1.56
DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes. Proc Natl Acad Sci U S A (2005) 1.53
Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone. Stem Cells (2007) 1.53
A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin. Mol Cell (2007) 1.52
Development and function of invariant natural killer T cells producing T(h)2- and T(h)17-cytokines. PLoS Biol (2012) 1.51
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Dilated cardiomyopathy caused by aberrant endoplasmic reticulum quality control in mutant KDEL receptor transgenic mice. Mol Cell Biol (2004) 1.48
Programmed induction of endoreduplication by DNA double-strand breaks in Arabidopsis. Proc Natl Acad Sci U S A (2011) 1.48
A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell. Nucleic Acids Res (2008) 1.47
Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes. Mol Cell Biol (2005) 1.46
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Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity. PLoS Genet (2012) 1.40
Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression. Stem Cells (2009) 1.39
Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation. EMBO J (2006) 1.37
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Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation. Immunity (2013) 1.36
Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes. Mol Endocrinol (2002) 1.35
Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication. Nature (2013) 1.35