Published in Development on May 13, 2004
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell (2009) 5.34
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell (2009) 4.69
Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells. Cell Stem Cell (2009) 3.02
T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways. Stem Cells (2008) 2.43
Wnt-mediated self-renewal of neural stem/progenitor cells. Proc Natl Acad Sci U S A (2008) 2.15
Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. Nat Cell Biol (2009) 1.94
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. PLoS Genet (2010) 1.77
Neural stem cell self-renewal. Crit Rev Oncol Hematol (2007) 1.76
Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. J Neurosci (2009) 1.72
A gene expression fingerprint of C. elegans embryonic motor neurons. BMC Genomics (2005) 1.72
Specification and morphogenesis of astrocytes. Science (2010) 1.67
Specific inhibition of CBP/beta-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation. Proc Natl Acad Sci U S A (2005) 1.67
Adenomatous polyposis coli protein deletion leads to cognitive and autism-like disabilities. Mol Psychiatry (2014) 1.52
Retracted Alteration of astrocytes and Wnt/β-catenin signaling in the frontal cortex of autistic subjects. J Neuroinflammation (2012) 1.51
Winding through the WNT pathway during cellular development and demise. Histol Histopathol (2006) 1.50
Cortical neural precursors inhibit their own differentiation via N-cadherin maintenance of beta-catenin signaling. Dev Cell (2010) 1.49
Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling. J Cell Biol (2005) 1.44
Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells. Mol Cell Biol (2008) 1.42
Neurogenesis at the brain-cerebrospinal fluid interface. Annu Rev Cell Dev Biol (2011) 1.42
Convergence of Notch and beta-catenin signaling induces arterial fate in vascular progenitors. J Cell Biol (2010) 1.39
The Wnt signaling pathway: aging gracefully as a protectionist? Pharmacol Ther (2008) 1.38
Sam68 regulates a set of alternatively spliced exons during neurogenesis. Mol Cell Biol (2008) 1.38
The way Wnt works: components and mechanism. Growth Factors (2012) 1.37
Beta-catenin-mediated Wnt signaling regulates neurogenesis in the ventral telencephalon. Nat Neurosci (2008) 1.32
Impaired neural development caused by inducible expression of Axin in transgenic mice. Mech Dev (2006) 1.32
Induction of neurogenesis in nonconventional neurogenic regions of the adult central nervous system by niche astrocyte-produced signals. Stem Cells (2008) 1.32
Wnt signaling regulates neuronal differentiation of cortical intermediate progenitors. J Neurosci (2011) 1.31
Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors. Dev Biol (2007) 1.26
Neurogenesis in the embryonic and adult brain: same regulators, different roles. Front Cell Neurosci (2014) 1.25
ephrinB1 signals from the cell surface to the nucleus by recruitment of STAT3. Proc Natl Acad Sci U S A (2007) 1.21
Beta-catenin up-regulates Atoh1 expression in neural progenitor cells by interaction with an Atoh1 3' enhancer. J Biol Chem (2009) 1.21
Aberrant beta-catenin signaling in tuberous sclerosis. Am J Pathol (2005) 1.20
Molecular control of neurogenesis: a view from the mammalian cerebral cortex. Cold Spring Harb Perspect Biol (2012) 1.13
WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum. Development (2012) 1.12
Caenorhabditis elegans as a model for stem cell biology. Dev Dyn (2010) 1.11
Canonical Wnt signaling is required for ophthalmic trigeminal placode cell fate determination and maintenance. Dev Biol (2007) 1.08
Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model. PLoS One (2012) 1.08
Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex. Neural Dev (2009) 1.08
Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells. J Cell Sci (2011) 1.07
Sca-1 knockout impairs myocardial and cardiac progenitor cell function. Circ Res (2012) 1.06
HMGA regulates the global chromatin state and neurogenic potential in neocortical precursor cells. Nat Neurosci (2012) 1.06
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Mol Psychiatry (2016) 1.05
Wnt signaling in the regulation of adult hippocampal neurogenesis. Front Cell Neurosci (2013) 1.04
Linking cell signaling and the epigenetic machinery. Nat Biotechnol (2010) 1.03
Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin. Mol Cell Biol (2012) 1.01
Transcription factor Lhx2 is necessary and sufficient to suppress astrogliogenesis and promote neurogenesis in the developing hippocampus. Proc Natl Acad Sci U S A (2011) 1.01
Beta-catenin signaling negatively regulates intermediate progenitor population numbers in the developing cortex. PLoS One (2010) 1.01
An activated protein C analog stimulates neuronal production by human neural progenitor cells via a PAR1-PAR3-S1PR1-Akt pathway. J Neurosci (2013) 1.00
Wnt signaling in vertebrate neural development and function. J Neuroimmune Pharmacol (2012) 1.00
Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1. Proc Natl Acad Sci U S A (2009) 0.98
Severe alterations of cerebellar cortical development after constitutive activation of Wnt signaling in granule neuron precursors. Mol Cell Biol (2011) 0.98
A noncoding RNA regulates the neurogenin1 gene locus during mouse neocortical development. Proc Natl Acad Sci U S A (2012) 0.98
Wnt signaling and forebrain development. Cold Spring Harb Perspect Biol (2012) 0.97
AKT activation by N-cadherin regulates beta-catenin signaling and neuronal differentiation during cortical development. Neural Dev (2013) 0.97
Ca2+-mediated mitochondrial reactive oxygen species metabolism augments Wnt/β-catenin pathway activation to facilitate cell differentiation. J Biol Chem (2014) 0.96
DISC1: a key lead in studying cortical development and associated brain disorders. Neuroscientist (2013) 0.96
Transcription factors and neural stem cell self-renewal, growth and differentiation. Cell Adh Migr (2009) 0.94
Focal reduction of alphaE-catenin causes premature differentiation and reduction of beta-catenin signaling during cortical development. Dev Biol (2009) 0.94
Prenatal β-catenin/Brn2/Tbr2 transcriptional cascade regulates adult social and stereotypic behaviors. Mol Psychiatry (2016) 0.94
β-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus. Development (2012) 0.93
Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development. Development (2014) 0.92
Wnt7a interaction with Fzd5 and detection of signaling activation using a split eGFP. Biochem Biophys Res Commun (2008) 0.92
Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev (2009) 0.92
En1 and Wnt signaling in midbrain dopaminergic neuronal development. Neural Dev (2011) 0.92
Identification of Wnt-responsive cells in the zebrafish hypothalamus. Zebrafish (2009) 0.92
Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation. Development (2013) 0.91
Wnt7a regulates multiple steps of neurogenesis. Mol Cell Biol (2013) 0.91
Dynamic signaling for neural stem cell fate determination. Cell Adh Migr (2009) 0.91
Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling. Nat Neurosci (2016) 0.91
Oxygen, a Key Factor Regulating Cell Behavior during Neurogenesis and Cerebral Diseases. Front Mol Neurosci (2011) 0.90
Gene expression profiling of embryonic human neural stem cells and dopaminergic neurons from adult human substantia nigra. PLoS One (2011) 0.90
Canonical Wnt signaling promotes the proliferation and neurogenesis of peripheral olfactory stem cells during postnatal development and adult regeneration. J Cell Sci (2011) 0.90
TF-Cluster: a pipeline for identifying functionally coordinated transcription factors via network decomposition of the shared coexpression connectivity matrix (SCCM). BMC Syst Biol (2011) 0.89
Emx3 is required for the differentiation of dorsal telencephalic neurons. Dev Dyn (2009) 0.89
Physiological role of β-catenin/TCF signaling in neurons of the adult brain. Neurochem Res (2013) 0.88
MYC proteins promote neuronal differentiation by controlling the mode of progenitor cell division. EMBO Rep (2014) 0.88
Canonical Wnt signalling requires the BMP pathway to inhibit oligodendrocyte maturation. ASN Neuro (2011) 0.87
Taste bud cells of adult mice are responsive to Wnt/β-catenin signaling: implications for the renewal of mature taste cells. Genesis (2011) 0.87
Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells (2014) 0.87
Growth factors improve neurogenesis and outcome after focal cerebral ischemia. J Neural Transm (Vienna) (2009) 0.87
Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes. Nat Med (2016) 0.87
The Wnt receptor Ryk controls specification of GABAergic neurons versus oligodendrocytes during telencephalon development. Development (2011) 0.87
Concise review: self-renewal in the central nervous system: neural stem cells from embryo to adult. Stem Cells Transl Med (2012) 0.86
StearoylCoA desaturase-5: a novel regulator of neuronal cell proliferation and differentiation. PLoS One (2012) 0.86
The crucial role of Atg5 in cortical neurogenesis during early brain development. Sci Rep (2014) 0.86
Smad6 promotes neuronal differentiation in the intermediate zone of the dorsal neural tube by inhibition of the Wnt/beta-catenin pathway. Proc Natl Acad Sci U S A (2011) 0.86
Plxdc2 is a mitogen for neural progenitors. PLoS One (2011) 0.85
Wnts blow on NeuroD1 to promote adult neuron production and diversity. Nat Neurosci (2009) 0.84
Neutralization of LINGO-1 during in vitro differentiation of neural stem cells results in proliferation of immature neurons. PLoS One (2012) 0.84
Zrf1 is required to establish and maintain neural progenitor identity. Genes Dev (2014) 0.84
Exposure to 1800 MHz radiofrequency radiation impairs neurite outgrowth of embryonic neural stem cells. Sci Rep (2014) 0.84
The p53 transcriptional target gene wnt7b contributes to NGF-inducible neurite outgrowth in neuronal PC12 cells. Differentiation (2008) 0.83
Involvement of the Wnt/β-catenin pathway in neurectoderm architecture in Platynereis dumerilii. Nat Commun (2013) 0.83
Thyroid hormone promotes neuronal differentiation of embryonic neural stem cells by inhibiting STAT3 signaling through TRα1. Stem Cells Dev (2012) 0.83
Wnt3a promotes hippocampal neurogenesis by shortening cell cycle duration of neural progenitor cells. Cell Mol Neurobiol (2010) 0.83
The role of β-catenin signaling pathway on proliferation of rats neural stem cells after hyperbaric oxygen therapy in vitro. Cell Mol Neurobiol (2010) 0.83
β-Catenin is critical for cerebellar foliation and lamination. PLoS One (2013) 0.82
Dynamic changes in Wnt signaling are required for neuronal differentiation of mouse embryonic stem cells. Mol Cell Neurosci (2011) 0.82
Genome evolution predicts genetic interactions in protein complexes and reveals cancer drug targets. Nat Commun (2013) 0.82
Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration. Dev Cell (2004) 4.05
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol (2005) 3.89
JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates. EMBO Rep (2001) 3.08
Akt enhances Mdm2-mediated ubiquitination and degradation of p53. J Biol Chem (2002) 3.01
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nat Cell Biol (2004) 2.75
DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway. Oncogene (2004) 2.73
Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits. Neuron (2010) 2.53
JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins. EMBO J (2004) 2.50
Mutated APC and Asef are involved in the migration of colorectal tumour cells. Nat Cell Biol (2003) 2.34
Multipolar migration: the third mode of radial neuronal migration in the developing cerebral cortex. J Neurosci (2003) 2.32
The muscle protein Dok-7 is essential for neuromuscular synaptogenesis. Science (2006) 2.26
Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition. Neuron (2009) 2.16
Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions. J Biol Chem (2003) 2.12
SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling. Nature (2002) 2.08
Retracted Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade. Nat Cell Biol (2003) 2.08
JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3. J Cell Biol (2005) 2.06
The impact of anti-HLA antibodies on unrelated cord blood transplantations. Blood (2010) 2.05
Scaffolding function of PAK in the PDK1-Akt pathway. Nat Cell Biol (2008) 2.02
Rab GTPases-dependent endocytic pathways regulate neuronal migration and maturation through N-cadherin trafficking. Neuron (2010) 1.95
Epigenetic control of neural precursor cell fate during development. Nat Rev Neurosci (2010) 1.93
Identification of a link between the tumour suppressor APC and the kinesin superfamily. Nat Cell Biol (2002) 1.93
Wnt/beta-catenin and estrogen signaling converge in vivo. J Biol Chem (2004) 1.60
The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria. J Biol Chem (2002) 1.60
RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling. J Biol Chem (2003) 1.58
DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature (2011) 1.53
Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone. Stem Cells (2007) 1.53
Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses. Arch Gen Psychiatry (2008) 1.51
Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development (2007) 1.40
Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands. Proc Natl Acad Sci U S A (2009) 1.40
COUP-TFII is preferentially expressed in the caudal ganglionic eminence and is involved in the caudal migratory stream. J Neurosci (2008) 1.38
Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes. Mol Endocrinol (2002) 1.35
Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells. J Biol Chem (2003) 1.31
The impact of HLA antibodies on engraftment of unrelated cord blood transplants. Transfusion (2008) 1.30
PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein augments the transforming activity in a rat fibroblast cell line. Virology (2004) 1.29
Cell-autonomous roles of ARX in cell proliferation and neuronal migration during corticogenesis. J Neurosci (2008) 1.28
Differing roles of Akt and serum- and glucocorticoid-regulated kinase in glucose metabolism, DNA synthesis, and oncogenic activity. J Biol Chem (2003) 1.25
Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex. Development (2006) 1.24
Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis. Dev Biol (2004) 1.23
DREG, a developmentally regulated G protein-coupled receptor containing two conserved proteolytic cleavage sites. Genes Cells (2004) 1.22
Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling. Cancer Res (2004) 1.21
USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney. Biochem Biophys Res Commun (2004) 1.20
Activation of the c-Jun N-terminal kinase pathway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis. Mol Cell Biol (2007) 1.19
Role of the kinesin-2 family protein, KIF3, during mitosis. J Biol Chem (2005) 1.18
The PI3K-Akt pathway promotes microtubule stabilization in migrating fibroblasts. Genes Cells (2007) 1.17
The caudal migratory stream: a novel migratory stream of interneurons derived from the caudal ganglionic eminence in the developing mouse forebrain. J Neurosci (2005) 1.17
Stage-dependent fate determination of neural precursor cells in mouse forebrain. Neurosci Res (2005) 1.17
The cyclin-dependent kinase inhibitors p57 and p27 regulate neuronal migration in the developing mouse neocortex. J Biol Chem (2006) 1.16
Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism. J Biol Chem (2006) 1.16
Anaphylactic transfusion reactions in haptoglobin-deficient patients with IgE and IgG haptoglobin antibodies. Transfusion (2002) 1.16
Akt-PDK1 complex mediates epidermal growth factor-induced membrane protrusion through Ral activation. Mol Biol Cell (2006) 1.15
Transcriptional regulation of the TGF-beta pseudoreceptor BAMBI by TGF-beta signaling. Biochem Biophys Res Commun (2004) 1.14
Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1. Neuron (2012) 1.14
The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol (2009) 1.13
Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli. Genes Cells (2006) 1.13
Regulation of the cell surface expression of human BCRP/ABCG2 by the phosphorylation state of Akt in polarized cells. Drug Metab Dispos (2005) 1.13
Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex. Development (2010) 1.13
The Sox-2 regulatory regions display their activities in two distinct types of multipotent stem cells. Mol Cell Biol (2004) 1.13
Labeling embryonic mouse central nervous system cells by in utero electroporation. Dev Growth Differ (2008) 1.12
Are all mouthguards the same and safe to use? The influence of occlusal supporting mouthguards in decreasing bone distortion and fractures. Dent Traumatol (2004) 1.12
Secreted Reelin molecules form homodimers. Neurosci Res (2002) 1.11
Neurons tend to stop migration and differentiate along the cortical internal plexiform zones in the Reelin signal-deficient mice. J Neurosci Res (2002) 1.11
Distinct roles of haptoglobin-related protein and apolipoprotein L-I in trypanolysis by human serum. Proc Natl Acad Sci U S A (2007) 1.10
Phosphorylation and activation of the Rac1 and Cdc42 GEF Asef in A431 cells stimulated by EGF. J Cell Sci (2008) 1.10
Differences of migratory behavior between direct progeny of apical progenitors and basal progenitors in the developing cerebral cortex. Cereb Cortex (2009) 1.09
The outermost region of the developing cortical plate is crucial for both the switch of the radial migration mode and the Dab1-dependent "inside-out" lamination in the neocortex. J Neurosci (2011) 1.08
Role of the Rho GTPase-activating protein RICS in neurite outgrowth. Genes Cells (2006) 1.08
Segregation and coactivation of developing neocortical layer 1 neurons. J Neurosci (2003) 1.08
Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalon. Development (2008) 1.07
HMGA regulates the global chromatin state and neurogenic potential in neocortical precursor cells. Nat Neurosci (2012) 1.06
Involvement of LKB1 in epithelial-mesenchymal transition (EMT) of human lung cancer cells. Lung Cancer (2010) 1.06
Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1. Development (2009) 1.05
Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin/TCF. Cancer Sci (2008) 1.05
Regulation of cortical neuron migration by the Reelin signaling pathway. Neurochem Res (2011) 1.03
Wnt signaling regulates the sequential onset of neurogenesis and gliogenesis via induction of BMPs. Genes Cells (2005) 1.02
Significant association of KIR2DL3-HLA-C1 combination with cerebral malaria and implications for co-evolution of KIR and HLA. PLoS Pathog (2012) 1.02
Anteriorization of neural fate by inhibitor of beta-catenin and T cell factor (ICAT), a negative regulator of Wnt signaling. Proc Natl Acad Sci U S A (2004) 1.02
Mechanisms that regulate the number of neurons during mouse neocortical development. Curr Opin Neurobiol (2010) 1.01
Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAi. Biochem Biophys Res Commun (2010) 1.01
α2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2. Nat Neurosci (2011) 1.00
Primary signet ring cell carcinoma of the prostate: report and review of 42 cases. Int J Urol (2004) 1.00
Abnormal development of urogenital organs in Dlgh1-deficient mice. Development (2007) 1.00
The tumor suppressor LKB1 induces p21 expression in collaboration with LMO4, GATA-6, and Ldb1. Biochem Biophys Res Commun (2006) 0.99
Donor killer immunoglobulin-like receptor (KIR) genotype-patient cognate KIR ligand combination and antithymocyte globulin preadministration are critical factors in outcome of HLA-C-KIR ligand-mismatched T cell-replete unrelated bone marrow transplantation. Biol Blood Marrow Transplant (2008) 0.99