Published in Biochem Biophys Res Commun on June 11, 2004
Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell (2010) 5.22
Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging? Free Radic Biol Med (2009) 2.00
Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan. Am J Pathol (2008) 1.56
Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice. FASEB J (2006) 1.54
Somatotropic signaling: trade-offs between growth, reproductive development, and longevity. Physiol Rev (2013) 1.50
Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: association with increased AGER1 expression. Am J Pathol (2007) 1.35
The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging. Aging (Albany NY) (2010) 1.21
The ERK-MAPK pathway regulates longevity through SKN-1 and insulin-like signaling in Caenorhabditis elegans. J Biol Chem (2010) 1.09
Hormonal control of aging in rodents: the somatotropic axis. Mol Cell Endocrinol (2008) 1.07
Longevity in mice: is stress resistance a common factor? Age (Dordr) (2006) 1.03
Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS). Aging (Albany NY) (2009) 0.93
Mitochondrial electron transport chain functions in long-lived Ames dwarf mice. Aging (Albany NY) (2011) 0.91
Lower levels of F2-isoprostanes in serum and livers of long-lived Ames dwarf mice. Biochem Biophys Res Commun (2007) 0.91
Metabolic syndrome, hormones, and maintenance of T cells during aging. Curr Opin Immunol (2010) 0.88
The somatotropic axis and longevity in mice. Am J Physiol Endocrinol Metab (2015) 0.87
Revealing system-level correlations between aging and calorie restriction using a mouse transcriptome. Age (Dordr) (2009) 0.81
Inhibition of adenylyl cyclase type 5 increases longevity and healthful aging through oxidative stress protection. Oxid Med Cell Longev (2015) 0.77
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature (2009) 19.56
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci (2010) 5.54
Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis. Am J Physiol Heart Circ Physiol (2009) 3.11
Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice. Aging Cell (2008) 2.65
An Aging Interventions Testing Program: study design and interim report. Aging Cell (2007) 2.54
'Matching Michigan': a 2-year stepped interventional programme to minimise central venous catheter-blood stream infections in intensive care units in England. BMJ Qual Saf (2012) 2.44
Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction. Aging Cell (2014) 2.35
Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation. J Cell Biol (2002) 2.34
The Snell dwarf mutation Pit1(dw) can increase life span in mice. Mech Ageing Dev (2002) 1.87
Akt/PKB and p38 MAPK signaling, translational initiation and longevity in Snell dwarf mouse livers. Mech Ageing Dev (2004) 1.76
Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell (2013) 1.71
WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis. Hum Mol Genet (2002) 1.70
Dda helicase tightly couples translocation on single-stranded DNA to unwinding of duplex DNA: Dda is an optimally active helicase. J Mol Biol (2012) 1.57
The mouse as a model for understanding chronic diseases of aging: the histopathologic basis of aging in inbred mice. Pathobiol Aging Age Relat Dis (2011) 1.56
Medullary amyloidosis associated with apolipoprotein A-IV deposition. Kidney Int (2011) 1.56
Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice. FASEB J (2006) 1.54
Profiling gene transcription reveals a deficiency of mitochondrial oxidative phosphorylation in Trypanosoma cruzi-infected murine hearts: implications in chagasic myocarditis development. Biochim Biophys Acta (2003) 1.53
The T4 phage SF1B helicase Dda is structurally optimized to perform DNA strand separation. Structure (2012) 1.52
Role of laminin terminal globular domains in basement membrane assembly. J Biol Chem (2007) 1.50
Diagnostic accuracy of chest X-rays acquired using a digital camera for low-cost teleradiology. Int J Med Inform (2004) 1.49
Laminin-sulfatide binding initiates basement membrane assembly and enables receptor signaling in Schwann cells and fibroblasts. J Cell Biol (2005) 1.46
Risk factors for invasive fungal disease in critically ill adult patients: a systematic review. Crit Care (2011) 1.44
Early peak temperature and mortality in critically ill patients with or without infection. Intensive Care Med (2012) 1.29
Adiponectin blocks interleukin-18-mediated endothelial cell death via APPL1-dependent AMP-activated protein kinase (AMPK) activation and IKK/NF-kappaB/PTEN suppression. J Biol Chem (2008) 1.26
Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases. Proc Natl Acad Sci U S A (2003) 1.26
Differential expression of hDAB2IPA and hDAB2IPB in normal tissues and promoter methylation of hDAB2IPA in hepatocellular carcinoma. J Hepatol (2006) 1.22
Gene expression analysis in mitochondria from chagasic mice: alterations in specific metabolic pathways. Biochem J (2004) 1.21
The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging. Aging (Albany NY) (2010) 1.21
Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo. J Neurochem (2007) 1.20
Carbonylation of ER chaperone proteins in aged mouse liver. Biochem Biophys Res Commun (2003) 1.19
Assessment and optimization of mortality prediction tools for admissions to pediatric intensive care in the United kingdom. Pediatrics (2006) 1.17
Effects of the Pit1 mutation on the insulin signaling pathway: implications on the longevity of the long-lived Snell dwarf mouse. Mech Ageing Dev (2002) 1.15
Perioperative increase in global blood flow to explicit defined goals and outcomes following surgery. Cochrane Database Syst Rev (2012) 1.12
Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains. Proc Natl Acad Sci U S A (2012) 1.12
Neutralization of interleukin-18 ameliorates ischemia/reperfusion-induced myocardial injury. J Biol Chem (2009) 1.11
Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like repressor element in the AP-endonuclease 1 promoter. Nucleic Acids Res (2002) 1.09
Age-related alterations in oxidatively damaged proteins of mouse skeletal muscle mitochondrial electron transport chain complexes. Free Radic Biol Med (2008) 1.08
Identification of dystroglycan as a second laminin receptor in oligodendrocytes, with a role in myelination. Development (2007) 1.08
Decreased enzyme activities of chaperones PDI and BiP in aged mouse livers. Biochem Biophys Res Commun (2007) 1.08
Evaluation of modernisation of adult critical care services in England: time series and cost effectiveness analysis. BMJ (2009) 1.07
Interleukin-18 knockout mice display maladaptive cardiac hypertrophy in response to pressure overload. Biochem Biophys Res Commun (2007) 1.07
Implications for the insulin signaling pathway in Snell dwarf mouse longevity: a similarity with the C. elegans longevity paradigm. Mech Ageing Dev (2002) 1.06
Altered cholesterologenic and lipogenic transcriptional profile in livers of aging Snell dwarf (Pit1dw/dwJ) mice. Aging Cell (2004) 1.06
P2X purinergic receptor-mediated ionic current in cardiac myocytes of calsequestrin model of cardiomyopathy: implications for the treatment of heart failure. Am J Physiol Heart Circ Physiol (2006) 1.06
The effect of aging on p38 signaling pathway activity in the mouse liver and in response to ROS generated by 3-nitropropionic acid. Mech Ageing Dev (2002) 1.05
Impaired mitochondrial respiratory chain and bioenergetics during chagasic cardiomyopathy development. Biochim Biophys Acta (2004) 1.03
Tumor necrosis factor-alpha and apoptosis signal-regulating kinase 1 control reactive oxygen species release, mitochondrial autophagy, and c-Jun N-terminal kinase/p38 phosphorylation during necrotizing enterocolitis. Oxid Med Cell Longev (2010) 1.03
Guidelines and considerations for conducting experiments using tissue microarrays. Histopathology (2013) 1.02
Age-associated changes in SAPK/JNK and p38 MAPK signaling in response to the generation of ROS by 3-nitropropionic acid. Mech Ageing Dev (2003) 1.01
Understanding the polymerization mechanism of glycoside-hydrolase family 70 glucansucrases. J Biol Chem (2006) 1.00
Persistence, switching, and discontinuation rates among patients receiving sertraline, paroxetine, and citalopram. Pharmacotherapy (2005) 0.99
Early temperature and mortality in critically ill patients with acute neurological diseases: trauma and stroke differ from infection. Intensive Care Med (2015) 0.99
Nitric-oxide supplementation for treatment of long-term complications in argininosuccinic aciduria. Am J Hum Genet (2012) 0.98
Identification of longevity-associated genes in long-lived Snell and Ames dwarf mice. Age (Dordr) (2006) 0.98
Age-related alterations in oxidatively damaged proteins of mouse heart mitochondrial electron transport chain complexes. Free Radic Biol Med (2008) 0.96
Age-related increases in oxidatively damaged proteins of mouse kidney mitochondrial electron transport chain complexes. Free Radic Biol Med (2007) 0.96
A detailed methodology of partial hepatectomy in the mouse. Lab Anim (NY) (2008) 0.96
Expression of the complement C3a and C5a receptors after permanent focal ischemia: An alternative interpretation. Glia (2002) 0.95
Localization of superoxide anion production to mitochondrial electron transport chain in 3-NPA-treated cells. Mitochondrion (2006) 0.95
The tumor suppressor gene DLEC1 is frequently silenced by DNA methylation in hepatocellular carcinoma and induces G1 arrest in cell cycle. J Hepatol (2007) 0.94
Neuroendocrine inhibition of glucose production and resistance to cancer in dwarf mice. Exp Gerontol (2008) 0.93
Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS). Aging (Albany NY) (2009) 0.93
Coexpression of RTI40 with alveolar epithelial type II cell proteins in lungs following injury: identification of alveolar intermediate cell types. Am J Physiol Lung Cell Mol Physiol (2005) 0.92
Mice severely deficient in growth hormone have normal hematopoiesis. Exp Hematol (2005) 0.92
Oxidative modification and aggregation of creatine kinase from aged mouse skeletal muscle. Aging (Albany NY) (2009) 0.92
Hepatic gene and protein expression of primary components of the IGF-I axis in long lived Snell dwarf mice. Mech Ageing Dev (2005) 0.92
Low utilization of circulating glucose after food withdrawal in Snell dwarf mice. J Biol Chem (2007) 0.92
The increasing burden of alcoholic liver disease on United Kingdom critical care units: secondary analysis of a high quality clinical database. J Health Serv Res Policy (2008) 0.91
Mitochondrial electron transport chain functions in long-lived Ames dwarf mice. Aging (Albany NY) (2011) 0.91
Gonadotropin-releasing hormone receptor levels and cell context affect tumor cell responses to agonist in vitro and in vivo. Cancer Res (2008) 0.91
Lower levels of F2-isoprostanes in serum and livers of long-lived Ames dwarf mice. Biochem Biophys Res Commun (2007) 0.91
Prognostic modelling in traumatic brain injury. BMJ (2008) 0.90
Hospitals' star ratings and clinical outcomes: ecological study. BMJ (2004) 0.89
The inflammation-induced down-regulation of plasma Fetuin-A (alpha2HS-Glycoprotein) in liver results from the loss of interaction between long C/EBP isoforms at two neighbouring binding sites. Nucleic Acids Res (2003) 0.89
Care managers' experiences in a collaborative care program for high risk mothers with depression. Psychosomatics (2012) 0.89
Applying hierarchical task analysis to medication administration errors. Appl Ergon (2005) 0.88
The diabetes-prone NZO/HlLt strain. I. Immunophenotypic comparison to the related NZB/BlNJ and NZW/LacJ strains. Lab Invest (2002) 0.85
Using clinical databases to evaluate healthcare interventions. Int J Technol Assess Health Care (2010) 0.84
Meta-analysis of gene expression in the mouse liver reveals biomarkers associated with inflammation increased early during aging. Mech Ageing Dev (2012) 0.84
Contributions of dysregulated energy metabolism to type 2 diabetes development in NZO/H1Lt mice with polygenic obesity. Metabolism (2004) 0.84
Skill needs for nurses in their role as health informatics professionals: a survey in the context of global health informatics education. Int J Med Inform (2005) 0.83
Matrix-free mass spectrometric imaging using laser desorption ionisation Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun Mass Spectrom (2011) 0.83
High-throughput liquid-liquid fractionation of multiple protein post-translational modifications. J Proteome Res (2009) 0.83
Activation of senescence and aging characteristics by mitochondrially generated ROS: how are they linked? Cell Cycle (2010) 0.83
Pituitary removal in adult mice increases life span. Mech Ageing Dev (2006) 0.82
The Design with Intent Method: a design tool for influencing user behaviour. Appl Ergon (2009) 0.82
Intestinal mitochondrial apoptotic signaling is activated during oxidative stress. Pediatr Surg Int (2011) 0.82
Implications of tyrosine phosphoproteomics in cervical carcinogenesis. J Carcinog (2008) 0.81
Sensitive, specific, and quantitative FTICR mass spectrometry of combinatorial post-translational modifications in intact histone H4. Anal Chem (2008) 0.81
A reduced peripheral blood CD4(+) lymphocyte proportion is a consistent ageing phenotype. Mech Ageing Dev (2002) 0.81
Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines. Bioorg Med Chem Lett (2012) 0.80