Published in Endocrinology on May 20, 2004
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proc Natl Acad Sci U S A (2005) 3.79
Increased hypothalamic GPR54 signaling: a potential mechanism for initiation of puberty in primates. Proc Natl Acad Sci U S A (2005) 3.16
Kisspeptin signaling in the brain. Endocr Rev (2009) 2.83
Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54. J Physiol (2004) 2.11
Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol. Endocrinology (2007) 1.98
The kiss/kissr systems are dispensable for zebrafish reproduction: evidence from gene knockout studies. Endocrinology (2014) 1.46
Postmenopausal increase in KiSS-1, GPR54, and luteinizing hormone releasing hormone (LHRH-1) mRNA in the basal hypothalamus of female rhesus monkeys. Peptides (2008) 1.09
Disrupted kisspeptin signaling in GnRH neurons leads to hypogonadotrophic hypogonadism. Mol Endocrinol (2014) 1.05
Estrogenic regulation of the GnRH neuron. Front Endocrinol (Lausanne) (2012) 1.00
From KISS1 to kisspeptins: An historical perspective and suggested nomenclature. Peptides (2008) 0.99
Manganese stimulates luteinizing hormone releasing hormone secretion in prepubertal female rats: hypothalamic site and mechanism of action. J Physiol (2006) 0.97
International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin receptor nomenclature, distribution, and function. Pharmacol Rev (2010) 0.95
Functional significance of GnRH and kisspeptin, and their cognate receptors in teleost reproduction. Front Endocrinol (Lausanne) (2013) 0.87
A potential mechanism for the sexual dimorphism in the onset of puberty and incidence of idiopathic central precocious puberty in children: sex-specific kisspeptin as an integrator of puberty signals. Front Endocrinol (Lausanne) (2012) 0.87
Kisspeptin and puberty in mammals. Adv Exp Med Biol (2013) 0.86
The regulation of reproductive neuroendocrine function by insulin and insulin-like growth factor-1 (IGF-1). Front Neuroendocrinol (2014) 0.85
Central pathways integrating metabolism and reproduction in teleosts. Front Endocrinol (Lausanne) (2014) 0.85
Effects of kisspeptin1 on electrical activity of an extrahypothalamic population of gonadotropin-releasing hormone neurons in medaka (Oryzias latipes). PLoS One (2012) 0.85
Social status regulates kisspeptin receptor mRNA in the brain of Astatotilapia burtoni. Gen Comp Endocrinol (2010) 0.83
Expression of kisspeptins and kiss receptors suggests a large range of functions for kisspeptin systems in the brain of the European sea bass. PLoS One (2013) 0.82
Structural and functional divergence of gonadotropin-inhibitory hormone from jawless fish to mammals. Front Endocrinol (Lausanne) (2014) 0.80
GnRH and gpcr: laser-captured single cell gene profiling. Fish Physiol Biochem (2005) 0.79
Neurokinin B-related Peptide Suppresses the Expression of GnRH I, Kiss2 and tac3 in the Brain of Mature Female Nile tilapia Oreochromis niloticus. Balsaenggwa Saengsig (2016) 0.79
Testing the Critical Window Hypothesis of Timing and Duration of Estradiol Treatment on Hypothalamic Gene Networks in Reproductively Mature and Aging Female Rats. Endocrinology (2015) 0.79
Melatonin induces follicle maturation in Danio rerio. PLoS One (2011) 0.79
Kisspeptin Activates Ankrd 26 Gene Expression in Migrating Embryonic GnRH Neurons. Front Endocrinol (Lausanne) (2016) 0.79
In silico analysis of the regulatory region of the Yellowtail Kingfish and Zebrafish Kiss and Kiss receptor genes. Fish Physiol Biochem (2012) 0.79
Increased expression of kisspeptin and GnRH forms in the brain of scombroid fish during final ovarian maturation and ovulation. Reprod Biol Endocrinol (2012) 0.79
Pacemaking kisspeptin neurons. Exp Physiol (2013) 0.78
Estradiol Membrane-Initiated Signaling and Female Reproduction. Compr Physiol (2015) 0.78
Thyroid Hormone Upregulates Hypothalamic kiss2 Gene in the Male Nile Tilapia, Oreochromis niloticus. Front Endocrinol (Lausanne) (2013) 0.78
Reproductive Neuroendocrine Pathways of Social Behavior. Front Endocrinol (Lausanne) (2016) 0.77
Three GnRH receptor types in laser-captured single cells of the cichlid pituitary display cellular and functional heterogeneity. Proc Natl Acad Sci U S A (2005) 0.76
A "Timed" Kiss Is Essential for Reproduction: Lessons from Mammalian Studies. Front Endocrinol (Lausanne) (2016) 0.76
Identification and characterization of kiss2 and kissr2 homologs in Paralichthys olivaceus. Fish Physiol Biochem (2016) 0.76
Photoperiod regulate gonad development via kisspeptin/kissr in hypothalamus and saccus vasculosus of Atlantic salmon (Salmo salar). PLoS One (2017) 0.75
Kisspeptin signalling and its roles in humans. Singapore Med J (2015) 0.75
Bpifcl modulates kiss2 expression under the influence of 11-ketotestosterone in female zebrafish. Sci Rep (2017) 0.75
Genomic signatures of local adaptation reveal source-sink dynamics in a high gene flow fish species. Sci Rep (2017) 0.75
Involvement of endoplasmic reticulum stress in insulin resistance and diabetes. J Biol Chem (2004) 3.94
Prognostic significance of peripheral monocytosis after reperfused acute myocardial infarction:a possible role for left ventricular remodeling. J Am Coll Cardiol (2002) 3.27
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis. Circulation (2004) 3.16
The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes. Diabetes (2005) 3.00
Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction. Blood (2004) 2.72
Low-dose aspirin for prevention of stroke in low-risk patients with atrial fibrillation: Japan Atrial Fibrillation Stroke Trial. Stroke (2005) 2.56
Xenografted human amniotic membrane-derived mesenchymal stem cells are immunologically tolerated and transdifferentiated into cardiomyocytes. Circ Res (2010) 2.56
Prognostic stratification of patients with vasospastic angina: a comprehensive clinical risk score developed by the Japanese Coronary Spasm Association. J Am Coll Cardiol (2013) 2.51
Control of root system architecture by DEEPER ROOTING 1 increases rice yield under drought conditions. Nat Genet (2013) 2.46
Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells. Nat Biotechnol (2005) 2.34
Sema3a maintains normal heart rhythm through sympathetic innervation patterning. Nat Med (2007) 2.16
Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury. Biochem Biophys Res Commun (2008) 2.04
Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis. Nat Med (2006) 2.03
Pulsatile cardiac tissue grafts using a novel three-dimensional cell sheet manipulation technique functionally integrates with the host heart, in vivo. Circ Res (2006) 2.02
Effects of simvastatin on the development of the atrial fibrillation substrate in dogs with congestive heart failure. Cardiovasc Res (2007) 2.02
Disease characterization using LQTS-specific induced pluripotent stem cells. Cardiovasc Res (2012) 1.95
Autoantibodies against M2-muscarinic acetylcholine receptors: new upstream targets in atrial fibrillation in patients with dilated cardiomyopathy. Eur Heart J (2004) 1.94
Targeted deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice. J Clin Invest (2005) 1.94
Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart. J Cell Biol (2005) 1.93
Effect of granulocyte-macrophage colony-stimulating factor inducer on left ventricular remodeling after acute myocardial infarction. J Am Coll Cardiol (2004) 1.87
Nerve growth factor is critical for cardiac sensory innervation and rescues neuropathy in diabetic hearts. Circulation (2006) 1.76
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction. Proc Natl Acad Sci U S A (2009) 1.74
Novel cardiac precursor-like cells from human menstrual blood-derived mesenchymal cells. Stem Cells (2008) 1.68
Clinical implications of provocation tests for coronary artery spasm: safety, arrhythmic complications, and prognostic impact: multicentre registry study of the Japanese Coronary Spasm Association. Eur Heart J (2012) 1.68
Randomized, multicenter, warfarin-controlled phase II study of edoxaban in Japanese patients with non-valvular atrial fibrillation. Circ J (2012) 1.67
Cardiac sympathetic rejuvenation: a link between nerve function and cardiac hypertrophy. Circ Res (2007) 1.65
Randomized trial of angiotensin II-receptor blocker vs. dihydropiridine calcium channel blocker in the treatment of paroxysmal atrial fibrillation with hypertension (J-RHYTHM II study). Europace (2010) 1.63
Impact of systemic acidosis on the development of malignant ventricular arrhythmias after reperfusion therapy for ST-elevation myocardial infarction. Circ J (2010) 1.62
Regulatory role of dendritic cells in postinfarction healing and left ventricular remodeling. Circulation (2012) 1.54
Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential. Mol Cell Biol (2005) 1.49
The kiss/kissr systems are dispensable for zebrafish reproduction: evidence from gene knockout studies. Endocrinology (2014) 1.46
Bone marrow-derived cells contribute to pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension. Chest (2005) 1.45
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochem Biophys Res Commun (2009) 1.44
A 19-year-old man with myocardial infarction and sitosterolemia. Intern Med (2003) 1.44
Clinical implications of "pure" Hisian pacing in addition to para-Hisian pacing for the diagnosis of supraventricular tachycardia. Heart Rhythm (2006) 1.44
Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart. Circ Res (2007) 1.44
Extraction of previously deployed stent by an entrapped cutting balloon due to the blade fracture. Catheter Cardiovasc Interv (2002) 1.42
Diagnostic capacity of 64-slice multidetector computed tomography for acute coronary syndrome in patients presenting with acute chest pain. Cardiology (2008) 1.42
Differential effects of carvedilol and metoprolol on renal function in patients with heart failure. Circ J (2010) 1.42
Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents. J Clin Invest (2010) 1.42
Marked improvement with sildenafil in a patient with primary pulmonary hypertension unresponsive to epoprostenol. Intern Med (2004) 1.41
Novel three-dimensional imaging of the anatomical relationship between the pulmonary vein and left atrium. Circ J (2009) 1.39
Role of high-mobility group box 1 protein in post-infarction healing process and left ventricular remodelling. Cardiovasc Res (2008) 1.35
Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease. J Cell Biol (2002) 1.33
Heart failure causes cholinergic transdifferentiation of cardiac sympathetic nerves via gp130-signaling cytokines in rodents. J Clin Invest (2010) 1.33
Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression. J Clin Invest (2004) 1.31
Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart. Circ Res (2009) 1.31
Long-term prognosis of probands with Brugada-pattern ST-elevation in leads V1-V3. Circ Arrhythm Electrophysiol (2009) 1.25
Prevalence of atrial fibrillation in the general population of Japan: an analysis based on periodic health examination. Int J Cardiol (2008) 1.24
Increased epicardial fat volume quantified by 64-multidetector computed tomography is associated with coronary atherosclerosis and totally occlusive lesions. Circ J (2009) 1.22
Cloning and expression of kiss2 in the zebrafish and medaka. Endocrinology (2008) 1.21
Role of Herp in the endoplasmic reticulum stress response. Genes Cells (2004) 1.19
Bone marrow-derived regenerated cardiomyocytes (CMG Cells) express functional adrenergic and muscarinic receptors. Circulation (2002) 1.19
Sexually dimorphic expression of estrogen receptor beta in the anteroventral periventricular nucleus of the rat preoptic area: implication in luteinizing hormone surge. Proc Natl Acad Sci U S A (2002) 1.18
Clinical characteristics and long-term prognosis of vasospastic angina patients who survived out-of-hospital cardiac arrest: multicenter registry study of the Japanese Coronary Spasm Association. Circ Arrhythm Electrophysiol (2011) 1.16
HIF-1-mediated activation of telomerase in cervical cancer cells. Oncogene (2004) 1.16
Peg3/Pw1 is involved in p53-mediated cell death pathway in brain ischemia/hypoxia. J Biol Chem (2001) 1.16
G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs. Cell Stem Cell (2010) 1.16
Anisotropic conduction properties in canine atria analyzed by high-resolution optical mapping: preferential direction of conduction block changes from longitudinal to transverse with increasing age. Circulation (2002) 1.15
Characterization of voltage-gated calcium currents in gonadotropin-releasing hormone neurons tagged with green fluorescent protein in rats. Endocrinology (2003) 1.15
Kisspeptin cells in the ewe brain respond to leptin and communicate with neuropeptide Y and proopiomelanocortin cells. Endocrinology (2010) 1.15
Involvement of endoplasmic reticulum (ER) stress in podocyte injury induced by excessive protein accumulation. Kidney Int (2005) 1.14
The significant cardiomyogenic potential of human umbilical cord blood-derived mesenchymal stem cells in vitro. Stem Cells (2007) 1.14
ORP150/HSP12A protects renal tubular epithelium from ischemia-induced cell death. FASEB J (2004) 1.11
Bone marrow derived cells are involved in the pathogenesis of cardiac hypertrophy in response to pressure overload. Circulation (2007) 1.10
A real-time three-dimensional echocardiographic quantitative analysis of left atrial function in left ventricular diastolic dysfunction. Am J Cardiol (2008) 1.09
Contrasting dynamics of radial O2-loss barrier induction and aerenchyma formation in rice roots of two lengths. Ann Bot (2010) 1.09
Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Hum Mol Genet (2006) 1.06
Using a customized DNA microarray for expression profiling of the estrogen-responsive genes to evaluate estrogen activity among natural estrogens and industrial chemicals. Environ Health Perspect (2004) 1.06
Cardiomyogenic potential of mesenchymal progenitors derived from human circulating CD14+ monocytes. Stem Cells Dev (2005) 1.05
Interleukin-6/soluble interleukin-6 receptor complex reduces infarct size via inhibiting myocardial apoptosis. Lab Invest (2005) 1.05
New ECG criteria for high-risk Brugada syndrome. Circ J (2003) 1.02
Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress. Mol Cell Biol (2006) 1.01
Role of vascular endothelial growth factor-A in development of abdominal aortic aneurysm. Cardiovasc Res (2011) 1.01
Vaticanol B, a resveratrol tetramer, regulates endoplasmic reticulum stress and inflammation. Am J Physiol Cell Physiol (2007) 1.01
Neurogenic potential of progenitors derived from human circulating CD14+ monocytes. Immunol Cell Biol (2006) 1.01
Administration of granulocyte colony-stimulating factor after myocardial infarction enhances the recruitment of hematopoietic stem cell-derived myofibroblasts and contributes to cardiac repair. Stem Cells (2007) 1.00
Serum C-reactive protein elevation predicts poor clinical outcome in patients with distal type acute aortic dissection: association with the occurrence of oxygenation impairment. Int J Cardiol (2005) 1.00
Coronary artery disease and a functional polymorphism of hTERT. Biochem Biophys Res Commun (2006) 1.00
Men's Health Study: epidemiology of erectile dysfunction and cardiovascular disease. Circ J (2003) 1.00
Resveratrol prevents the development of abdominal aortic aneurysm through attenuation of inflammation, oxidative stress, and neovascularization. Atherosclerosis (2011) 0.97
Can the life span of human marrow stromal cells be prolonged by bmi-1, E6, E7, and/or telomerase without affecting cardiomyogenic differentiation? J Gene Med (2004) 0.97
'Working' cardiomyocytes exhibiting plateau action potentials from human placenta-derived extraembryonic mesodermal cells. Exp Cell Res (2007) 0.96
Granulocyte colony-stimulating factor attenuates early ventricular expansion after experimental myocardial infarction. Cardiovasc Res (2005) 0.95
ORP150/HSP12A regulates Purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar development. J Neurosci (2004) 0.95
Role of EGF Receptor and Pyk2 in endothelin-1-induced ERK activation in rat cardiomyocytes. J Mol Cell Cardiol (2002) 0.94
Autoimmunity against the second extracellular loop of beta(1)-adrenergic receptors induces early afterdepolarization and decreases in K-channel density in rabbits. J Am Coll Cardiol (2004) 0.94
GABAA receptors mediate excitation in adult rat GnRH neurons. Biol Reprod (2009) 0.94
Role of ischemic preconditioning and inflammatory response in the development of malignant ventricular arrhythmias after reperfused ST-elevation myocardial infarction. J Card Fail (2009) 0.94
Up-regulation of 150-kDa oxygen-regulated protein by celecoxib in human gastric carcinoma cells. Mol Pharmacol (2006) 0.93
Extrinsic compression of the left main coronary artery by atrial septal defect. Ann Thorac Surg (2008) 0.93
Selective involvement of p130Cas/Crk/Pyk2/c-Src in endothelin-1-induced JNK activation. Hypertension (2003) 0.93
Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin. Am J Physiol Cell Physiol (2006) 0.92
SHP2-mediated signaling cascade through gp130 is essential for LIF-dependent I CaL, [Ca2+]i transient, and APD increase in cardiomyocytes. J Mol Cell Cardiol (2007) 0.92
Increased C-reactive protein expression exacerbates left ventricular dysfunction and remodeling after myocardial infarction. Am J Physiol Heart Circ Physiol (2010) 0.92
Nifekalant versus lidocaine for in-hospital shock-resistant ventricular fibrillation or tachycardia. Resuscitation (2009) 0.92
RFamide peptides as mediators in environmental control of GnRH neurons. Prog Neurobiol (2012) 0.92
Zac1 is an essential transcription factor for cardiac morphogenesis. Circ Res (2010) 0.91