Published in Peptides on July 03, 2008
Kisspeptin signaling in the brain. Endocr Rev (2009) 2.83
Sex differences in the adolescent brain. Brain Cogn (2009) 2.20
Melanin-concentrating hormone directly inhibits GnRH neurons and blocks kisspeptin activation, linking energy balance to reproduction. Proc Natl Acad Sci U S A (2009) 1.22
Neuroendocrine control by kisspeptins: role in metabolic regulation of fertility. Nat Rev Endocrinol (2011) 1.17
The kisspeptin-GnRH pathway in human reproductive health and disease. Hum Reprod Update (2014) 1.13
International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin receptor nomenclature, distribution, and function. Pharmacol Rev (2010) 0.95
Evolutionary Insights into the Steroid Sensitive kiss1 and kiss2 Neurons in the Vertebrate Brain. Front Endocrinol (Lausanne) (2012) 0.87
Organizational and activational effects of sex steroids on kisspeptin neuron development. Front Neuroendocrinol (2012) 0.86
Kisspeptin/KISS1R System in Breast Cancer. J Cancer (2013) 0.85
Social status regulates kisspeptin receptor mRNA in the brain of Astatotilapia burtoni. Gen Comp Endocrinol (2010) 0.83
Decrease in hypothalamic Kiss1 and Kiss1r expression: a potential mechanism for fasting-induced suppression of the HPG axis in the adult male rhesus monkey (Macaca mulatta). Horm Metab Res (2010) 0.82
Studies of the localisation of kisspeptin within the pituitary of the rhesus monkey (Macaca mulatta) and the effect of kisspeptin on the release of non-gonadotropic pituitary hormones. J Neuroendocrinol (2009) 0.82
KISS1 and KISS1R expression in the human and rat carotid body and superior cervical ganglion. Eur J Histochem (2011) 0.81
Comprehensive Review on Kisspeptin and Its Role in Reproductive Disorders. Endocrinol Metab (Seoul) (2015) 0.79
Role of the adipocyte-derived hormone leptin in reproductive control. Horm Mol Biol Clin Investig (2014) 0.78
Kisspeptin signalling in the physiology and pathophysiology of the urogenital system. Nat Rev Urol (2015) 0.77
Response to exogenous kisspeptin varies according to sex and reproductive condition in Siberian hamsters (Phodopus sungorus). Gen Comp Endocrinol (2010) 0.76
Kisspeptin Regulation of Neuronal Activity throughout the Central Nervous System. Endocrinol Metab (Seoul) (2016) 0.76
The effect of Kisspeptin-10 on mesenchymal stem cells migration in vitro and in vivo. Adv Biomed Res (2015) 0.76
Kisspeptin signalling and its roles in humans. Singapore Med J (2015) 0.75
Kisspeptins in human reproduction-future therapeutic potential. J Assist Reprod Genet (2012) 0.75
Kisspeptin: A Potential Factor for Unexplained Infertility and Impaired Embryo Implantation. Int J Fertil Steril (2017) 0.75
The GPR54 gene as a regulator of puberty. N Engl J Med (2003) 9.54
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proc Natl Acad Sci U S A (2003) 7.64
The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem (2001) 4.77
Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature (2001) 4.55
Regulation of Kiss1 gene expression in the brain of the female mouse. Endocrinology (2005) 4.48
A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology (2004) 4.24
KiSS-1, a novel human malignant melanoma metastasis-suppressor gene. J Natl Cancer Inst (1996) 4.16
Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty. J Neurosci (2005) 4.04
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proc Natl Acad Sci U S A (2005) 3.79
Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat. Neuroendocrinology (2005) 3.52
Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide. Endocrinology (2004) 3.34
AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1. J Biol Chem (2001) 3.32
Increased hypothalamic GPR54 signaling: a potential mechanism for initiation of puberty in primates. Proc Natl Acad Sci U S A (2005) 3.16
The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system. Biochem Biophys Res Commun (2003) 3.09
Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males. J Clin Endocrinol Metab (2005) 3.08
Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone neurons. Endocrinology (2006) 2.95
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene. Proc Natl Acad Sci U S A (2007) 2.66
Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat. Biochem Biophys Res Commun (2004) 2.55
A GPR54-activating mutation in a patient with central precocious puberty. N Engl J Med (2008) 2.53
Differential regulation of KiSS-1 mRNA expression by sex steroids in the brain of the male mouse. Endocrinology (2005) 2.50
Kiss1 neurons in the forebrain as central processors for generating the preovulatory luteinizing hormone surge. J Neurosci (2006) 2.42
Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1. Cancer Res (1997) 2.27
Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis. J Neuroendocrinol (2004) 2.27
Sexual differentiation of Kiss1 gene expression in the brain of the rat. Endocrinology (2007) 2.20
Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54. J Physiol (2004) 2.11
Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts. J Cell Sci (2004) 2.08
Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats. Endocrinology (2005) 2.05
Discovery of a receptor related to the galanin receptors. FEBS Lett (1999) 2.01
Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol. Endocrinology (2007) 1.98
KiSS-1 neurones are direct targets for leptin in the ob/ob mouse. J Neuroendocrinol (2006) 1.92
Hypothalamic pathways linking energy balance and reproduction. Am J Physiol Endocrinol Metab (2008) 1.75
Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys. J Clin Endocrinol Metab (2007) 1.72
The role of kisspeptin-GPR54 signaling in the tonic regulation and surge release of gonadotropin-releasing hormone/luteinizing hormone. J Neurosci (2007) 1.69
Transcriptional expression of genes involved in cell invasion and migration by normal and tumoral trophoblast cells. J Clin Endocrinol Metab (2002) 1.60
The role of kisspeptins and GPR54 in the neuroendocrine regulation of reproduction. Annu Rev Physiol (2008) 1.53
KiSS-1 represses 92-kDa type IV collagenase expression by down-regulating NF-kappa B binding to the promoter as a consequence of Ikappa Balpha -induced block of p65/p50 nuclear translocation. J Biol Chem (2001) 1.51
Laser-captured single digoxigenin-labeled neurons of gonadotropin-releasing hormone types reveal a novel G protein-coupled receptor (Gpr54) during maturation in cichlid fish. Endocrinology (2004) 1.43
Identification and characterization of mouse metastasis-suppressor KiSS1 and its G-protein-coupled receptor. Cancer Res (2002) 1.38
Identification of highly expressed genes in metastasis-suppressed chromosome 6/human malignant melanoma hybrid cells using subtractive hybridization and differential display. Int J Cancer (1997) 1.29
Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats. Diabetes (2006) 1.26
Metastin receptor is overexpressed in papillary thyroid cancer and activates MAP kinase in thyroid cancer cells. J Clin Endocrinol Metab (2002) 1.24
Kisspeptin mediates the photoperiodic control of reproduction in hamsters. Curr Biol (2006) 1.23
FMRFamide-related neuropeptides are agonists of the orphan G-protein-coupled receptor GPR54. Biochem Biophys Res Commun (2001) 1.20
Inhibition of metastin (kisspeptin-54)-GPR54 signaling in the arcuate nucleus-median eminence region during lactation in rats. Endocrinology (2007) 1.20
A role for kisspeptin in islet function. Diabetologia (2006) 1.18
Expression of KiSS-1 in rat ovary: putative local regulator of ovulation? Endocrinology (2006) 1.17
Opposite roles of estrogen receptor (ER)-alpha and ERbeta in the modulation of luteinizing hormone responses to kisspeptin in the female rat: implications for the generation of the preovulatory surge. Endocrinology (2008) 1.14
KiSS-1 and GPR54 genes are co-expressed in rat gonadotrophs and differentially regulated in vivo by oestradiol and gonadotrophin-releasing hormone. J Neuroendocrinol (2008) 1.11
Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system. Br J Pharmacol (2007) 1.11
KISS1 metastasis suppression and emergent pathways. Clin Exp Metastasis (2003) 1.09
Identification of KiSS-1 product kisspeptin and steroid-sensitive sexually dimorphic kisspeptin neurons in medaka (oryzias latipes). Endocrinology (2008) 1.05
Kisspeptins are novel potent vasoconstrictors in humans, with a discrete localization of their receptor, G protein-coupled receptor 54, to atherosclerosis-prone vessels. Endocrinology (2006) 1.04
In vivo and in situ modulation of the expression of genes involved in metastasis and angiogenesis in a patient treated with topical imiquimod for melanoma skin metastases. Br J Dermatol (2004) 1.03
Suppression of kisspeptin expression and gonadotropic axis sensitivity following exposure to inhibitory day lengths in female Siberian hamsters. Horm Behav (2007) 1.01
Comparative analysis of the effects of ghrelin and unacylated ghrelin on luteinizing hormone secretion in male rats. Endocrinology (2006) 0.99
KiSS-1 mRNA in adipose tissue is regulated by sex hormones and food intake. Mol Cell Endocrinol (2007) 0.94
Central and peripheral administration of kisspeptin activates gonadotropin but not somatotropin secretion in prepubertal gilts. Reproduction (2008) 0.93
Peripheral administration of kisspeptin-10 increases plasma concentrations of GH as well as LH in prepubertal Holstein heifers. J Endocrinol (2008) 0.92
Kisspeptin-13 inhibits insulin secretion without affecting glucagon or somatostatin release: study in the perfused rat pancreas. J Endocrinol (2008) 0.88
Kisspeptin in reproduction. Semin Reprod Med (2007) 0.83
The KiSS-1/GPR54 system: putative target for endocrine disruption of reproduction at hypothalamic-pituitary unit? Int J Androl (2007) 0.78
Regulation of Kiss1 gene expression in the brain of the female mouse. Endocrinology (2005) 4.48
Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty. J Neurosci (2005) 4.04
Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat. Neuroendocrinology (2005) 3.52
Kisspeptin signaling in the brain. Endocr Rev (2009) 2.83
Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse. J Neurosci (2009) 2.78
Differential regulation of KiSS-1 mRNA expression by sex steroids in the brain of the male mouse. Endocrinology (2005) 2.50
Kiss1 neurons in the forebrain as central processors for generating the preovulatory luteinizing hormone surge. J Neurosci (2006) 2.42
Sexual differentiation of Kiss1 gene expression in the brain of the rat. Endocrinology (2007) 2.20
Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation. J Neurosci (2009) 2.07
Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat. Am J Physiol Endocrinol Metab (2010) 1.76
Regulation of Kiss1 expression by sex steroids in the amygdala of the rat and mouse. Endocrinology (2011) 1.75
Minireview: kisspeptin neurons as central processors in the regulation of gonadotropin-releasing hormone secretion. Endocrinology (2005) 1.75
The role of kisspeptin-GPR54 signaling in the tonic regulation and surge release of gonadotropin-releasing hormone/luteinizing hormone. J Neurosci (2007) 1.69
The role of kisspeptins and GPR54 in the neuroendocrine regulation of reproduction. Annu Rev Physiol (2008) 1.53
Activation of the sympathetic nervous system by galanin-like peptide--a possible link between leptin and metabolism. Endocrinology (2003) 1.52
Redundancy in Kiss1 expression safeguards reproduction in the mouse. Endocrinology (2013) 1.49
Emerging ideas about kisspeptin- GPR54 signaling in the neuroendocrine regulation of reproduction. Trends Neurosci (2007) 1.43
Regulation of Kiss1 and dynorphin gene expression in the murine brain by classical and nonclassical estrogen receptor pathways. J Neurosci (2009) 1.41
The kisspeptin receptor GPR54 is required for sexual differentiation of the brain and behavior. J Neurosci (2007) 1.41
Sex differences in the regulation of Kiss1/NKB neurons in juvenile mice: implications for the timing of puberty. Am J Physiol Endocrinol Metab (2009) 1.40
Circadian regulation of Kiss1 neurons: implications for timing the preovulatory gonadotropin-releasing hormone/luteinizing hormone surge. Endocrinology (2009) 1.39
Regulation of the neuroendocrine reproductive axis by kisspeptin-GPR54 signaling. Reproduction (2006) 1.32
Cloning and distribution of galanin-like peptide mRNA in the hypothalamus and pituitary of the macaque. Endocrinology (2002) 1.23
Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse. Endocrinology (2011) 1.21
Role of neurokinin B in the control of female puberty and its modulation by metabolic status. J Neurosci (2012) 1.13
Neuropeptide signaling in the integration of metabolism and reproduction. Neuroendocrinology (2007) 1.10
A role for galanin-like peptide in the integration of feeding, body weight regulation, and reproduction in the mouse. Endocrinology (2003) 1.10
The neuropeptide galanin modulates behavioral and neurochemical signs of opiate withdrawal. Proc Natl Acad Sci U S A (2003) 1.07
Increased neurokinin B (Tac2) expression in the mouse arcuate nucleus is an early marker of pubertal onset with differential sensitivity to sex steroid-negative feedback than Kiss1. Endocrinology (2012) 1.02
Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2). Mol Cell Biol (2005) 0.98
Analysis of the contribution of galanin receptors 1 and 2 to the central actions of galanin-like peptide. Neuroendocrinology (2004) 0.97
Galanin-like peptide as a link in the integration of metabolism and reproduction. Trends Endocrinol Metab (2004) 0.91
Molecular mechanisms that drive estradiol-dependent burst firing of Kiss1 neurons in the rostral periventricular preoptic area. Am J Physiol Endocrinol Metab (2013) 0.89
Neuroendocrine profiles in galanin-overexpressing and knockout mice. Neuroendocrinology (2003) 0.89
Galanin-like peptide rescues reproductive function in the diabetic rat. Diabetes (2005) 0.89
Differential patterns of Fos induction in the hypothalamus of the rat following central injections of galanin-like peptide and galanin. Endocrinology (2003) 0.89
Effects of diabetes and insulin on the expression of galanin-like peptide in the hypothalamus of the rat. Diabetes (2004) 0.88
Galanin overexpressing transgenic mice. Neuropeptides (2002) 0.86
Interactions between neurotensin and GnRH neurons in the positive feedback control of GnRH/LH secretion in the mouse. Am J Physiol Endocrinol Metab (2009) 0.82
Galanin-like peptide as a possible link between metabolism and reproduction in the macaque. J Clin Endocrinol Metab (2004) 0.80
Seasonal changes in androgen receptor mRNA in the brain of the white-crowned sparrow. Gen Comp Endocrinol (2009) 0.80
Altered response to metabolic challenges in mice with genetically targeted deletions of galanin-like peptide. Am J Physiol Endocrinol Metab (2008) 0.78
Galanin-Like peptide elicits a robust discharge of growth hormone in the rhesus monkey (Macaca mulatta). Neuroendocrinology (2005) 0.77
A KiSS to remember. Trends Endocrinol Metab (2005) 0.77
TACkling NKB's role in puberty. Endocrinology (2015) 0.75
κ Agonists as a novel therapy for menopausal hot flashes. Menopause (2015) 0.75
Distribution and Regulation of Galanin-Like Peptide (GALP) in the Hypothalamus of the Mouse. Endocrinology (2001) 0.75
Galanin-Like Peptide (GALP) Is a Target for Regulation by Leptin in the Hypothalamus of the Rat. Endocrinology (2000) 0.75