Published in J Cell Sci on May 15, 2004
The physics of cancer: the role of physical interactions and mechanical forces in metastasis. Nat Rev Cancer (2011) 3.42
A 3-D computational model predicts that cell deformation affects selectin-mediated leukocyte rolling. Biophys J (2004) 1.98
Loss of alpha-catenin decreases the strength of single E-cadherin bonds between human cancer cells. J Biol Chem (2009) 1.73
Force history dependence of receptor-ligand dissociation. Biophys J (2004) 1.61
Indentation and adhesive probing of a cell membrane with AFM: theoretical model and experiments. Biophys J (2005) 1.56
{alpha}-Catenin mediates initial E-cadherin-dependent cell-cell recognition and subsequent bond strengthening. Proc Natl Acad Sci U S A (2008) 1.31
Single-molecule analysis of human immunodeficiency virus type 1 gp120-receptor interactions in living cells. J Virol (2005) 1.28
Podocalyxin-like protein is an E-/L-selectin ligand on colon carcinoma cells: comparative biochemical properties of selectin ligands in host and tumor cells. Am J Physiol Cell Physiol (2008) 1.23
Biomechanics of leukocyte rolling. Biorheology (2011) 1.20
Roles of cell and microvillus deformation and receptor-ligand binding kinetics in cell rolling. Am J Physiol Heart Circ Physiol (2008) 1.15
Neutrophil-bead collision assay: pharmacologically induced changes in membrane mechanics regulate the PSGL-1/P-selectin adhesion lifetime. Biophys J (2005) 1.06
Dynamic force spectroscopy of glycoprotein Ib-IX and von Willebrand factor. Biophys J (2005) 0.99
LFA-1 binding destabilizes the JAM-A homophilic interaction during leukocyte transmigration. Biophys J (2009) 0.98
Monitoring early fusion dynamics of human immunodeficiency virus type 1 at single-molecule resolution. J Virol (2008) 0.97
Single-molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer. J Cell Sci (2011) 0.96
Molecular mechanistic insights into the endothelial receptor mediated cytoadherence of Plasmodium falciparum-infected erythrocytes. PLoS One (2011) 0.96
Mucin 16 is a functional selectin ligand on pancreatic cancer cells. FASEB J (2011) 0.96
Enhancement of L-selectin, but not P-selectin, bond formation frequency by convective flow. Biophys J (2007) 0.94
Regulation of catch bonds by rate of force application. J Biol Chem (2011) 0.94
Simultaneous tether extraction contributes to neutrophil rolling stabilization: a model study. Biophys J (2006) 0.93
Action at a distance: lengthening adhesion bonds with poly(ethylene glycol) spacers enhances mechanically stressed affinity for improved vascular targeting of microparticles. Langmuir (2009) 0.89
Dissociation rate constants of human fibronectin binding to fibronectin-binding proteins on living Staphylococcus aureus isolated from clinical patients. J Biol Chem (2012) 0.89
AFM as a tool to probe and manipulate cellular processes. Pflugers Arch (2007) 0.86
The Effects of Load on E-Selectin Bond Rupture and Bond Formation. Cell Mol Bioeng (2010) 0.85
Design, synthesis, physical and chemical characterisation, and biological interactions of lectin-targeted latex nanoparticles bearing Gd-DTPA chelates: an exploration of magnetic resonance molecular imaging (MRMI). Histochem Cell Biol (2005) 0.85
A hot-spot motif characterizes the interface between a designed ankyrin-repeat protein and its target ligand. Biophys J (2012) 0.83
The viscoelastic properties of microvilli are dependent upon the cell-surface molecule. Biochem Biophys Res Commun (2010) 0.82
Mechanochemitry: a molecular biomechanics view of mechanosensing. Ann Biomed Eng (2013) 0.82
Characterization of monobody scaffold interactions with ligand via force spectroscopy and steered molecular dynamics. Sci Rep (2015) 0.82
Distinct kinetic and mechanical properties govern mucin 16- and podocalyxin-mediated tumor cell adhesion to E- and L-selectin in shear flow. Oncotarget (2015) 0.80
Atomic force microscopy reveals a role for endothelial cell ICAM-1 expression in bladder cancer cell adherence. PLoS One (2014) 0.80
Distinct kinetic and molecular requirements govern CD44 binding to hyaluronan versus fibrin(ogen). Biophys J (2012) 0.79
A comparative molecular force spectroscopy study of homophilic JAM-A interactions and JAM-A interactions with reovirus attachment protein sigma1. J Mol Recognit (2008) 0.79
Sialyl Lewisx-dependent binding of human monocyte-derived dendritic cells to selectins. Biochem Biophys Res Commun (2011) 0.78
β-Catenin serves as a clutch between low and high intercellular E-cadherin bond strengths. Biophys J (2013) 0.77
Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways. Cell Rep (2016) 0.77
Adhesion and fusion efficiencies of human immunodeficiency virus type 1 (HIV-1) surface proteins. Sci Rep (2013) 0.77
A High-Throughput Technique Reveals the Load- and Site Density-Dependent Kinetics of E-Selectin. Cell Mol Bioeng (2012) 0.76
Analytical cell adhesion chromatography reveals impaired persistence of metastatic cell rolling adhesion to P-selectin. J Cell Sci (2015) 0.76
Probing time-dependent mechanical behaviors of catch bonds based on two-state models. Sci Rep (2015) 0.76
Comparison of human and mouse E-selectin binding to Sialyl-Lewis(x). BMC Struct Biol (2016) 0.75
E-selectin-mediated rolling facilitates pancreatic cancer cell adhesion to hyaluronic acid. FASEB J (2017) 0.75
A distinctive role for focal adhesion proteins in three-dimensional cell motility. Nat Cell Biol (2010) 3.84
The physics of cancer: the role of physical interactions and mechanical forces in metastasis. Nat Rev Cancer (2011) 3.42
A perinuclear actin cap regulates nuclear shape. Proc Natl Acad Sci U S A (2009) 3.12
Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin. J Cell Biol (2005) 2.89
Micromechanical mapping of live cells by multiple-particle-tracking microrheology. Biophys J (2002) 2.63
Micro- and macrorheology of mucus. Adv Drug Deliv Rev (2009) 2.54
Efficient active transport of gene nanocarriers to the cell nucleus. Proc Natl Acad Sci U S A (2003) 2.52
Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness. Exp Cell Res (2008) 2.52
Nuclear lamin A/C deficiency induces defects in cell mechanics, polarization, and migration. Biophys J (2007) 2.51
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Proc Natl Acad Sci U S A (2011) 2.17
Micro-organization and visco-elasticity of the interphase nucleus revealed by particle nanotracking. J Cell Sci (2004) 2.17
Intracellular mechanics of migrating fibroblasts. Mol Biol Cell (2004) 2.06
MinC spatially controls bacterial cytokinesis by antagonizing the scaffolding function of FtsZ. Curr Biol (2008) 2.02
Enhanced viscoelasticity of human cystic fibrotic sputum correlates with increasing microheterogeneity in particle transport. J Biol Chem (2003) 2.01
Mapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking. Biophys J (2008) 1.99
E-selectin receptors on human leukocytes. Blood (2008) 1.99
A 3-D computational model predicts that cell deformation affects selectin-mediated leukocyte rolling. Biophys J (2004) 1.98
Single molecule characterization of P-selectin/ligand binding. J Biol Chem (2003) 1.96
Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models. Biophys J (2008) 1.92
Mechanics and dynamics of actin-driven thin membrane protrusions. Biophys J (2005) 1.91
Structure of the actin crosslinking core of fimbrin. Structure (2004) 1.82
Fibronectin fibrillogenesis regulates three-dimensional neovessel formation. Genes Dev (2008) 1.81
Physical confinement alters tumor cell adhesion and migration phenotypes. FASEB J (2012) 1.74
Loss of alpha-catenin decreases the strength of single E-cadherin bonds between human cancer cells. J Biol Chem (2009) 1.73
The bimodal role of filamin in controlling the architecture and mechanics of F-actin networks. J Biol Chem (2003) 1.70
Single-molecule analysis of cadherin-mediated cell-cell adhesion. J Cell Sci (2006) 1.70
The assembly of MreB, a prokaryotic homolog of actin. J Biol Chem (2004) 1.67
Probing single-cell micromechanics in vivo: the microrheology of C. elegans developing embryos. Biophys J (2006) 1.66
Ballistic intracellular nanorheology reveals ROCK-hard cytoplasmic stiffening response to fluid flow. J Cell Sci (2006) 1.60
Rho kinase regulates the intracellular micromechanical response of adherent cells to rho activation. Mol Biol Cell (2004) 1.57
Collagen prolyl hydroxylases are essential for breast cancer metastasis. Cancer Res (2013) 1.51
Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow. J Biol Chem (2008) 1.51
Morphology of the lamellipodium and organization of actin filaments at the leading edge of crawling cells. Biophys J (2005) 1.50
Towards a regional approach to cell mechanics. Trends Cell Biol (2004) 1.46
Condensation of FtsZ filaments can drive bacterial cell division. Proc Natl Acad Sci U S A (2008) 1.46
Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts. J Biol Chem (2013) 1.44
A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo. J Cell Biol (2003) 1.44
Colon carcinoma cell glycolipids, integrins, and other glycoproteins mediate adhesion to HUVECs under flow. Am J Physiol Cell Physiol (2002) 1.43
Mechanics of enveloped virus entry into host cells. Biophys J (2005) 1.40
Magnetic tweezers measurement of single molecule torque. Nano Lett (2009) 1.40
Focal adhesion size uniquely predicts cell migration. FASEB J (2012) 1.40
Microrheology and ROCK signaling of human endothelial cells embedded in a 3D matrix. Biophys J (2006) 1.39
Cdc42 mediates nucleus movement and MTOC polarization in Swiss 3T3 fibroblasts under mechanical shear stress. Mol Biol Cell (2004) 1.39
Selectin ligand expression regulates the initial vascular interactions of colon carcinoma cells: the roles of CD44v and alternative sialofucosylated selectin ligands. J Biol Chem (2006) 1.39
Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis. Mol Cancer Res (2013) 1.38
Altering mucus rheology to "solidify" human mucus at the nanoscale. PLoS One (2009) 1.37
The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration. Sci Rep (2012) 1.36
Distinct signaling mechanisms regulate migration in unconfined versus confined spaces. J Cell Biol (2013) 1.34
A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep (2013) 1.33
Receptor-ligand binding: 'catch' bonds finally caught. Curr Biol (2003) 1.32
{alpha}-Catenin mediates initial E-cadherin-dependent cell-cell recognition and subsequent bond strengthening. Proc Natl Acad Sci U S A (2008) 1.31
Three-dimensional cell migration does not follow a random walk. Proc Natl Acad Sci U S A (2014) 1.30
Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners. Nat Commun (2012) 1.30
Actin cap associated focal adhesions and their distinct role in cellular mechanosensing. Sci Rep (2012) 1.29
Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis. Proc Natl Acad Sci U S A (2005) 1.28
Variant isoforms of CD44 are P- and L-selectin ligands on colon carcinoma cells. FASEB J (2005) 1.28
Single-molecule analysis of human immunodeficiency virus type 1 gp120-receptor interactions in living cells. J Virol (2005) 1.28
GTPase activity, structure, and mechanical properties of filaments assembled from bacterial cytoskeleton protein MreB. J Bacteriol (2006) 1.24
Podocalyxin-like protein is an E-/L-selectin ligand on colon carcinoma cells: comparative biochemical properties of selectin ligands in host and tumor cells. Am J Physiol Cell Physiol (2008) 1.23
CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activity. Cancer Res (2005) 1.23
Chemotaxis of cell populations through confined spaces at single-cell resolution. PLoS One (2012) 1.22
Biomechanics of leukocyte rolling. Biorheology (2011) 1.20
Transport of polymeric nanoparticle gene carriers in gastric mucus. Biotechnol Prog (2004) 1.20
Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-kappaB activation. Am J Physiol Cell Physiol (2010) 1.20
Mesothelin binding to CA125/MUC16 promotes pancreatic cancer cell motility and invasion via MMP-7 activation. Sci Rep (2013) 1.19
Probing cellular mechanical responses to stimuli using ballistic intracellular nanorheology. Methods Cell Biol (2007) 1.19
Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells. Proc Natl Acad Sci U S A (2013) 1.19
Real-time intracellular transport of gene nanocarriers studied by multiple particle tracking. Biotechnol Prog (2004) 1.19
Shear-induced interleukin-6 synthesis in chondrocytes: roles of E prostanoid (EP) 2 and EP3 in cAMP/protein kinase A- and PI3-K/Akt-dependent NF-kappaB activation. J Biol Chem (2010) 1.18
Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments. Mol Biol Cell (2002) 1.17
Cross-linking FtsZ polymers into coherent Z rings. Mol Microbiol (2010) 1.17
High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity. Anal Chem (2013) 1.16
Programmed subcellular release for studying the dynamics of cell detachment. Nat Methods (2009) 1.15
Roles of cell and microvillus deformation and receptor-ligand binding kinetics in cell rolling. Am J Physiol Heart Circ Physiol (2008) 1.15
Polymerization and bundling kinetics of FtsZ filaments. Biophys J (2008) 1.14
The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction. Sci Rep (2013) 1.13
Metabolic flux increases glycoprotein sialylation: implications for cell adhesion and cancer metastasis. Mol Cell Proteomics (2012) 1.13
Mucin 16 (cancer antigen 125) expression in human tissues and cell lines and correlation with clinical outcome in adenocarcinomas of the pancreas, esophagus, stomach, and colon. Hum Pathol (2012) 1.13
Resolving the role of actoymyosin contractility in cell microrheology. PLoS One (2009) 1.13
How actin crosslinking and bundling proteins cooperate to generate an enhanced cell mechanical response. Biochem Biophys Res Commun (2005) 1.13
A direct interaction between actin and vimentin filaments mediated by the tail domain of vimentin. J Biol Chem (2006) 1.12
Nuclear envelope breakdown requires overcoming the mechanical integrity of the nuclear lamina. J Biol Chem (2004) 1.12
The mechanical properties of simple epithelial keratins 8 and 18: discriminating between interfacial and bulk elasticities. J Struct Biol (2003) 1.11
Defective blood vessel development and pericyte/pvSMC distribution in alpha 4 integrin-deficient mouse embryos. Dev Biol (2006) 1.11
Asymmetric enrichment of PIE-1 in the Caenorhabditis elegans zygote mediated by binary counterdiffusion. J Cell Biol (2009) 1.11
Fluid shear- and time-dependent modulation of molecular interactions between PMNs and colon carcinomas. Am J Physiol Cell Physiol (2002) 1.11
Shear-induced cyclooxygenase-2 via a JNK2/c-Jun-dependent pathway regulates prostaglandin receptor expression in chondrocytic cells. J Biol Chem (2003) 1.11
Sialofucosylated podocalyxin is a functional E- and L-selectin ligand expressed by metastatic pancreatic cancer cells. Am J Physiol Cell Physiol (2012) 1.09
The perinuclear actin cap in health and disease. Nucleus (2010) 1.09
The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells. PLoS One (2012) 1.09
Divergent roles of CD44 and carcinoembryonic antigen in colon cancer metastasis. FASEB J (2012) 1.07
The Arp2/3 complex mediates multigeneration dendritic protrusions for efficient 3-dimensional cancer cell migration. FASEB J (2013) 1.07
Platelet-induced enhancement of LS174T colon carcinoma and THP-1 monocytoid cell adhesion to vascular endothelium under flow. Am J Physiol Cell Physiol (2004) 1.05
A perspective on microarrays: current applications, pitfalls, and potential uses. Microb Cell Fact (2007) 1.05
Differences in the microrheology of human embryonic stem cells and human induced pluripotent stem cells. Biophys J (2010) 1.04
The dual role of CD44 as a functional P-selectin ligand and fibrin receptor in colon carcinoma cell adhesion. Am J Physiol Cell Physiol (2008) 1.04