Published in J Cell Sci on April 15, 2004
Dynamics of single mRNPs in nuclei of living cells. Science (2004) 4.58
Physical plasticity of the nucleus in stem cell differentiation. Proc Natl Acad Sci U S A (2007) 4.30
The physics of cancer: the role of physical interactions and mechanical forces in metastasis. Nat Rev Cancer (2011) 3.42
Mechanism of mRNA transport in the nucleus. Proc Natl Acad Sci U S A (2005) 3.25
Micro- and macrorheology of mucus. Adv Drug Deliv Rev (2009) 2.54
Power-law rheology of isolated nuclei with deformation mapping of nuclear substructures. Biophys J (2005) 2.19
Mapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking. Biophys J (2008) 1.99
Probing single-cell micromechanics in vivo: the microrheology of C. elegans developing embryos. Biophys J (2006) 1.66
Nuclear body movement is determined by chromatin accessibility and dynamics. Proc Natl Acad Sci U S A (2004) 1.52
Probing the nanoscale viscoelasticity of intracellular fluids in living cells. Biophys J (2007) 1.44
Microenvironment and effect of energy depletion in the nucleus analyzed by mobility of multiple oligomeric EGFPs. Biophys J (2006) 1.41
Mechanical properties of the cell nucleus and the effect of emerin deficiency. Biophys J (2006) 1.40
Microrheology and ROCK signaling of human endothelial cells embedded in a 3D matrix. Biophys J (2006) 1.39
Cdc42 mediates nucleus movement and MTOC polarization in Swiss 3T3 fibroblasts under mechanical shear stress. Mol Biol Cell (2004) 1.39
Spatially Resolved Quantification of Chromatin Condensation through Differential Local Rheology in Cell Nuclei Fluorescence Lifetime Imaging. PLoS One (2016) 1.38
The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration. Sci Rep (2012) 1.36
Bio-microrheology: a frontier in microrheology. Biophys J (2006) 1.23
Mechanical regulation of nuclear structure and function. Annu Rev Biomed Eng (2012) 1.19
Mobility of multi-subunit complexes in the nucleus: accessibility and dynamics of chromatin subcompartments. Histochem Cell Biol (2005) 1.17
Mechanochemical delivery and dynamic tracking of fluorescent quantum dots in the cytoplasm and nucleus of living cells. Nano Lett (2009) 1.15
Anisotropic rheology and directional mechanotransduction in vascular endothelial cells. Proc Natl Acad Sci U S A (2008) 1.14
The perinuclear actin cap in health and disease. Nucleus (2010) 1.09
DNA relaxation dynamics as a probe for the intracellular environment. Proc Natl Acad Sci U S A (2009) 1.08
Noncontact three-dimensional mapping of intracellular hydromechanical properties by Brillouin microscopy. Nat Methods (2015) 1.07
Early spindle assembly in Drosophila embryos: role of a force balance involving cytoskeletal dynamics and nuclear mechanics. Mol Biol Cell (2005) 1.03
Universal algorithm for identification of fractional Brownian motion. A case of telomere subdiffusion. Biophys J (2012) 1.02
4-D single particle tracking of synthetic and proteinaceous microspheres reveals preferential movement of nuclear particles along chromatin - poor tracks. BMC Cell Biol (2004) 1.02
A continuous-binding cross-linker model for passive airway smooth muscle. Biophys J (2010) 0.98
Magnetic manipulation of nanorods in the nucleus of living cells. Biophys J (2011) 0.97
High-throughput ballistic injection nanorheology to measure cell mechanics. Nat Protoc (2012) 0.96
Chromatin hydrodynamics. Biophys J (2014) 0.95
Computational and experimental models of cancer cell response to fluid shear stress. Front Oncol (2013) 0.95
Parvovirus induced alterations in nuclear architecture and dynamics. PLoS One (2009) 0.93
Dynamics of passive and active particles in the cell nucleus. PLoS One (2012) 0.93
Dissecting chromatin interactions in living cells from protein mobility maps. Chromosome Res (2011) 0.92
Can visco-elastic phase separation, macromolecular crowding and colloidal physics explain nuclear organisation? Theor Biol Med Model (2007) 0.92
Dispersion-relation phase spectroscopy of intracellular transport. Opt Express (2011) 0.91
Force-induced changes in subnuclear movement and rheology. Biophys J (2012) 0.89
Chromosome dynamics, molecular crowding, and diffusion in the interphase cell nucleus: a Monte Carlo lattice simulation study. Chromosome Res (2011) 0.89
Nuclear mechanics in cancer. Adv Exp Med Biol (2014) 0.88
Biomechanical approaches for studying integration of tissue structure and function in mammary epithelia. J Mammary Gland Biol Neoplasia (2004) 0.86
Particle tracking in drug and gene delivery research: State-of-the-art applications and methods. Adv Drug Deliv Rev (2015) 0.86
Leukocyte rolling on P-selectin: a three-dimensional numerical study of the effect of cytoplasmic viscosity. Biophys J (2012) 0.85
Experimental techniques for study of chromatin mechanics in intact nuclei and living cells. Chromosome Res (2008) 0.85
Mechanics of the nucleus. Compr Physiol (2011) 0.85
Effects of cytoskeletal disruption on transport, structure, and rheology within mammalian cells. Phys Fluids (1994) (2007) 0.84
Transverse mechanical properties of cell walls of single living plant cells probed by laser-generated acoustic waves. Planta (2014) 0.84
Remodeling nuclear architecture allows efficient transport of herpesvirus capsids by diffusion. Proc Natl Acad Sci U S A (2015) 0.83
Collaborative homologous pairing during C. elegans meiosis. Worm (2012) 0.82
Dynamic organization of transcription compartments is dependent on functional nuclear architecture. Biophys J (2012) 0.81
Intracellular manipulation of chromatin using magnetic nanoparticles. Chromosome Res (2008) 0.81
Herpes simplex virus 1 induces egress channels through marginalized host chromatin. Sci Rep (2016) 0.78
New approaches for understanding the nuclear force balance in living, adherent cells. Methods (2015) 0.77
Forces, fluctuations, and self-organization in the nucleus. Mol Biol Cell (2015) 0.76
Geometric observers for dynamically evolving curves. IEEE Trans Pattern Anal Mach Intell (2008) 0.75
Mechanobiology of Chromatin and the Nuclear Interior. Cell Mol Bioeng (2016) 0.75
The diffusive way out: Herpesviruses remodel the host nucleus, enabling capsids to access the inner nuclear membrane. Nucleus (2016) 0.75
Rupture Dynamics and Chromatin Herniation in Deformed Nuclei. Biophys J (2017) 0.75
The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity (2009) 6.86
Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Deliv Rev (2008) 4.80
A distinctive role for focal adhesion proteins in three-dimensional cell motility. Nat Cell Biol (2010) 3.84
A perinuclear actin cap regulates nuclear shape. Proc Natl Acad Sci U S A (2009) 3.12
Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin. J Cell Biol (2005) 2.89
Micromechanical mapping of live cells by multiple-particle-tracking microrheology. Biophys J (2002) 2.63
Micro- and macrorheology of mucus. Adv Drug Deliv Rev (2009) 2.54
A role for mammalian target of rapamycin in regulating T cell activation versus anergy. J Immunol (2007) 2.53
Efficient active transport of gene nanocarriers to the cell nucleus. Proc Natl Acad Sci U S A (2003) 2.52
Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness. Exp Cell Res (2008) 2.52
Nuclear lamin A/C deficiency induces defects in cell mechanics, polarization, and migration. Biophys J (2007) 2.51
Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach. Mol Cell Proteomics (2014) 2.37
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Proc Natl Acad Sci U S A (2011) 2.17
Intracellular mechanics of migrating fibroblasts. Mol Biol Cell (2004) 2.06
MinC spatially controls bacterial cytokinesis by antagonizing the scaffolding function of FtsZ. Curr Biol (2008) 2.02
Enhanced viscoelasticity of human cystic fibrotic sputum correlates with increasing microheterogeneity in particle transport. J Biol Chem (2003) 2.01
Mapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking. Biophys J (2008) 1.99
Single molecule characterization of P-selectin/ligand binding. J Biol Chem (2003) 1.96
Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models. Biophys J (2008) 1.92
Mechanics and dynamics of actin-driven thin membrane protrusions. Biophys J (2005) 1.91
Structure of the actin crosslinking core of fimbrin. Structure (2004) 1.82
Fibronectin fibrillogenesis regulates three-dimensional neovessel formation. Genes Dev (2008) 1.81
Loss of alpha-catenin decreases the strength of single E-cadherin bonds between human cancer cells. J Biol Chem (2009) 1.73
The bimodal role of filamin in controlling the architecture and mechanics of F-actin networks. J Biol Chem (2003) 1.70
Single-molecule analysis of cadherin-mediated cell-cell adhesion. J Cell Sci (2006) 1.70
The assembly of MreB, a prokaryotic homolog of actin. J Biol Chem (2004) 1.67
Probing single-cell micromechanics in vivo: the microrheology of C. elegans developing embryos. Biophys J (2006) 1.66
Ballistic intracellular nanorheology reveals ROCK-hard cytoplasmic stiffening response to fluid flow. J Cell Sci (2006) 1.60
Rho kinase regulates the intracellular micromechanical response of adherent cells to rho activation. Mol Biol Cell (2004) 1.57
Distinct kinetic and mechanical properties govern selectin-leukocyte interactions. J Cell Sci (2004) 1.54
Collagen prolyl hydroxylases are essential for breast cancer metastasis. Cancer Res (2013) 1.51
Morphology of the lamellipodium and organization of actin filaments at the leading edge of crawling cells. Biophys J (2005) 1.50
Inhibition of tumor-cell invasion with chlorotoxin-bound superparamagnetic nanoparticles. Small (2009) 1.49
Towards a regional approach to cell mechanics. Trends Cell Biol (2004) 1.46
Condensation of FtsZ filaments can drive bacterial cell division. Proc Natl Acad Sci U S A (2008) 1.46
Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts. J Biol Chem (2013) 1.44
A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo. J Cell Biol (2003) 1.44
Mechanics of enveloped virus entry into host cells. Biophys J (2005) 1.40
Magnetic tweezers measurement of single molecule torque. Nano Lett (2009) 1.40
Focal adhesion size uniquely predicts cell migration. FASEB J (2012) 1.40
Microrheology and ROCK signaling of human endothelial cells embedded in a 3D matrix. Biophys J (2006) 1.39
Cdc42 mediates nucleus movement and MTOC polarization in Swiss 3T3 fibroblasts under mechanical shear stress. Mol Biol Cell (2004) 1.39
Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis. Mol Cancer Res (2013) 1.38
Altering mucus rheology to "solidify" human mucus at the nanoscale. PLoS One (2009) 1.37
The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration. Sci Rep (2012) 1.36
A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep (2013) 1.33
Receptor-ligand binding: 'catch' bonds finally caught. Curr Biol (2003) 1.32
{alpha}-Catenin mediates initial E-cadherin-dependent cell-cell recognition and subsequent bond strengthening. Proc Natl Acad Sci U S A (2008) 1.31
Three-dimensional cell migration does not follow a random walk. Proc Natl Acad Sci U S A (2014) 1.30
Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners. Nat Commun (2012) 1.30
Actin cap associated focal adhesions and their distinct role in cellular mechanosensing. Sci Rep (2012) 1.29
Single-molecule analysis of human immunodeficiency virus type 1 gp120-receptor interactions in living cells. J Virol (2005) 1.28
GTPase activity, structure, and mechanical properties of filaments assembled from bacterial cytoskeleton protein MreB. J Bacteriol (2006) 1.24
Transport of polymeric nanoparticle gene carriers in gastric mucus. Biotechnol Prog (2004) 1.20
Probing cellular mechanical responses to stimuli using ballistic intracellular nanorheology. Methods Cell Biol (2007) 1.19
Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells. Proc Natl Acad Sci U S A (2013) 1.19
Real-time intracellular transport of gene nanocarriers studied by multiple particle tracking. Biotechnol Prog (2004) 1.19
Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments. Mol Biol Cell (2002) 1.17
Cross-linking FtsZ polymers into coherent Z rings. Mol Microbiol (2010) 1.17
High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity. Anal Chem (2013) 1.16
Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites. Biochemistry (2007) 1.16
Programmed subcellular release for studying the dynamics of cell detachment. Nat Methods (2009) 1.15
Polymerization and bundling kinetics of FtsZ filaments. Biophys J (2008) 1.14
The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction. Sci Rep (2013) 1.13
How actin crosslinking and bundling proteins cooperate to generate an enhanced cell mechanical response. Biochem Biophys Res Commun (2005) 1.13
Resolving the role of actoymyosin contractility in cell microrheology. PLoS One (2009) 1.13
A direct interaction between actin and vimentin filaments mediated by the tail domain of vimentin. J Biol Chem (2006) 1.12
Nuclear envelope breakdown requires overcoming the mechanical integrity of the nuclear lamina. J Biol Chem (2004) 1.12
The mechanical properties of simple epithelial keratins 8 and 18: discriminating between interfacial and bulk elasticities. J Struct Biol (2003) 1.11
Asymmetric enrichment of PIE-1 in the Caenorhabditis elegans zygote mediated by binary counterdiffusion. J Cell Biol (2009) 1.11
The perinuclear actin cap in health and disease. Nucleus (2010) 1.09
The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells. PLoS One (2012) 1.09
Divergent roles of CD44 and carcinoembryonic antigen in colon cancer metastasis. FASEB J (2012) 1.07
The Arp2/3 complex mediates multigeneration dendritic protrusions for efficient 3-dimensional cancer cell migration. FASEB J (2013) 1.07
Differences in the microrheology of human embryonic stem cells and human induced pluripotent stem cells. Biophys J (2010) 1.04
Microheterogeneity and microrheology of wheat gliadin suspensions studied by multiple-particle tracking. Biomacromolecules (2002) 1.04
Probing intercellular interactions between vascular endothelial cadherin pairs at single-molecule resolution and in living cells. J Mol Biol (2006) 1.04
Mismatch in mechanical and adhesive properties induces pulsating cancer cell migration in epithelial monolayer. Biophys J (2012) 1.03
Alpha-actinin and filamin cooperatively enhance the stiffness of actin filament networks. PLoS One (2009) 1.03
The filamentous actin cross-linking/bundling activity of mammalian formins. J Mol Biol (2008) 1.01
Intracellular microrheology as a tool for the measurement of the local mechanical properties of live cells. Methods Cell Biol (2004) 0.98
Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation. Mol Immunol (2009) 0.98
Magnetic manipulation of nanorods in the nucleus of living cells. Biophys J (2011) 0.97
Monitoring early fusion dynamics of human immunodeficiency virus type 1 at single-molecule resolution. J Virol (2008) 0.97
PEG-based hydrogels with collagen mimetic peptide-mediated and tunable physical cross-links. Biomacromolecules (2010) 0.97
Dendritic branching and homogenization of actin networks mediated by arp2/3 complex. Phys Rev Lett (2004) 0.97
SMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarization. J Cell Sci (2011) 0.96
Single-molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer. J Cell Sci (2011) 0.96