Published in Biochem Biophys Res Commun on July 02, 2004
Characterization of human glutaredoxin 2 as iron-sulfur protein: a possible role as redox sensor. Proc Natl Acad Sci U S A (2005) 1.68
Mechanistic and kinetic details of catalysis of thiol-disulfide exchange by glutaredoxins and potential mechanisms of regulation. Antioxid Redox Signal (2009) 1.50
Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling. Antioxid Redox Signal (2013) 1.48
A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses. Antioxid Redox Signal (2010) 1.38
Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significance. Antioxid Redox Signal (2012) 1.36
Regulation by reversible S-glutathionylation: molecular targets implicated in inflammatory diseases. Mol Cells (2008) 1.26
Modulation of glutaredoxin in the lung and sputum of cigarette smokers and chronic obstructive pulmonary disease. Respir Res (2006) 1.22
The thiol pool in human plasma: the central contribution of albumin to redox processes. Free Radic Biol Med (2013) 1.18
Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductase. J Biol Chem (2009) 1.16
Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide. Proc Natl Acad Sci U S A (2004) 1.16
Both thioredoxin 2 and glutaredoxin 2 contribute to the reduction of the mitochondrial 2-Cys peroxiredoxin Prx3. J Biol Chem (2010) 1.14
Redox regulation of cell survival by the thioredoxin superfamily: an implication of redox gene therapy in the heart. Antioxid Redox Signal (2009) 1.08
A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: implications for Parkinson's disease. Antioxid Redox Signal (2009) 1.03
Penultimate selenocysteine residue replaced by cysteine in thioredoxin reductase from selenium-deficient rat liver. FASEB J (2009) 0.96
Glutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity. Hum Mol Genet (2010) 0.96
Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients. Respir Res (2007) 0.93
Cell-mediated reduction of human β-defensin 1: a major role for mucosal thioredoxin. Mucosal Immunol (2013) 0.91
Increased glutaredoxin-1 and decreased protein S-glutathionylation in sputum of asthmatics. Eur Respir J (2013) 0.87
Attenuated cardiovascular hypertrophy and oxidant generation in response to angiotensin II infusion in glutaredoxin-1 knockout mice. Free Radic Biol Med (2010) 0.86
Macrophage activation and polarization modify P2X7 receptor secretome influencing the inflammatory process. Sci Rep (2016) 0.80
Methodological aspects of ELISA analysis of thioredoxin 1 in human plasma and cerebrospinal fluid. PLoS One (2014) 0.77
Glutaredoxin mediated redox effects of coenzyme Q10 treatment in type 1 and type 2 diabetes patients. BBA Clin (2015) 0.75
From structure to redox: the diverse functional roles of disulfides and implications in disease. Proteomics (2017) 0.75
Interpreting Heterogeneity in Response of Cells Expressing a Fluorescent Hydrogen Peroxide Biosensor. Biophys J (2015) 0.75
Thioredoxin and related molecules--from biology to health and disease. Antioxid Redox Signal (2007) 3.50
From selenium to selenoproteins: synthesis, identity, and their role in human health. Antioxid Redox Signal (2007) 3.49
Glutaredoxins: glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system. Antioxid Redox Signal (2004) 3.04
Glutaredoxin systems. Biochim Biophys Acta (2008) 2.65
The thioredoxin system in cancer. Semin Cancer Biol (2006) 2.42
Probing the chemistry of thioredoxin catalysis with force. Nature (2007) 2.17
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide. Proc Natl Acad Sci U S A (2007) 2.11
Selenoproteins. J Biol Chem (2008) 2.02
Glutathionylation of human thioredoxin: a possible crosstalk between the glutathione and thioredoxin systems. Proc Natl Acad Sci U S A (2002) 2.00
Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system. Am J Physiol Heart Circ Physiol (2006) 1.99
Folding of human superoxide dismutase: disulfide reduction prevents dimerization and produces marginally stable monomers. Proc Natl Acad Sci U S A (2004) 1.89
Thioredoxins and glutaredoxins as facilitators of protein folding. Biochim Biophys Acta (2008) 1.85
Identification of S-glutathionylated cellular proteins during oxidative stress and constitutive metabolism by affinity purification and proteomic analysis. Arch Biochem Biophys (2002) 1.78
Characterization of human glutaredoxin 2 as iron-sulfur protein: a possible role as redox sensor. Proc Natl Acad Sci U S A (2005) 1.68
Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity. J Biol Chem (2005) 1.64
Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase. J Biol Chem (2003) 1.55
A left paraglossal approach for oral intubation in children scheduled for bilateral orofacial cleft reconstruction surgery--a prospective observational study. Paediatr Anaesth (2009) 1.48
Inhibition of Mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity. Cancer Res (2006) 1.48
Whistle: another method of induction of pediatric anesthesia. Paediatr Anaesth (2007) 1.46
Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity. J Biol Chem (2008) 1.45
Abnormal branch of the testicular artery. Clin Anat (2006) 1.43
Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors. BMC Cancer (2012) 1.39
Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductase. J Biol Chem (2006) 1.33
Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. J Clin Invest (2010) 1.33
Thioredoxin system in cell death progression. Antioxid Redox Signal (2012) 1.32
Regulation of the catalytic activity and structure of human thioredoxin 1 via oxidation and S-nitrosylation of cysteine residues. J Biol Chem (2008) 1.32
Single-molecule paleoenzymology probes the chemistry of resurrected enzymes. Nat Struct Mol Biol (2011) 1.32
Chaperone properties of Escherichia coli thioredoxin and thioredoxin reductase. Biochem J (2003) 1.30
Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase. Biochem Pharmacol (2009) 1.28
Sample size estimation in prevalence studies. Indian J Pediatr (2012) 1.27
Pathobiological implications of MUC16 expression in pancreatic cancer. PLoS One (2011) 1.26
Inhibition of thioredoxin and thioredoxin reductase by 4-hydroxy-2-nonenal in vitro and in vivo. J Am Chem Soc (2006) 1.25
Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia. PLoS One (2009) 1.25
The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function. Mol Cell Biol (2006) 1.25
Rod-derived Cone Viability Factor-2 is a novel bifunctional-thioredoxin-like protein with therapeutic potential. BMC Mol Biol (2007) 1.24
Reversible silencing of CFTR chloride channels by glutathionylation. J Gen Physiol (2005) 1.22
Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release. Biochem Biophys Res Commun (2005) 1.21
Molecular and structural basis for redox regulation of beta-actin. J Mol Biol (2007) 1.20
Folate, vitamin B12, and homocysteine levels in South Asian women with growth-retarded fetuses. Acta Obstet Gynecol Scand (2005) 1.20
Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-beta in vitro and in interstitial lung diseases in vivo. Hum Pathol (2004) 1.19
A novel monothiol glutaredoxin (Grx4) from Escherichia coli can serve as a substrate for thioredoxin reductase. J Biol Chem (2005) 1.19
Protein folding drives disulfide formation. Cell (2012) 1.18
Hydrogen and polyhydroxybutyrate producing abilities of microbes from diverse habitats by dark fermentative process. Bioresour Technol (2007) 1.17
Mucins in pancreatic cancer and its microenvironment. Nat Rev Gastroenterol Hepatol (2013) 1.17
Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductase. J Biol Chem (2009) 1.16
Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide. Proc Natl Acad Sci U S A (2004) 1.16
A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase. J Biol Chem (2002) 1.16
The crystal structure of human GLRX5: iron-sulfur cluster co-ordination, tetrameric assembly and monomer activity. Biochem J (2011) 1.15
Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant. Proc Natl Acad Sci U S A (2002) 1.15
Late-onset intermittent fasting dietary restriction as a potential intervention to retard age-associated brain function impairments in male rats. Age (Dordr) (2011) 1.14
Truncated thioredoxin: physiological functions and mechanism. Antioxid Redox Signal (2004) 1.13
Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy. Nat Struct Mol Biol (2009) 1.11
Oxidation and S-nitrosylation of cysteines in human cytosolic and mitochondrial glutaredoxins: effects on structure and activity. J Biol Chem (2007) 1.11
Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione. FASEB J (2012) 1.09
Selenium and selenoproteins in health and disease. Antioxid Redox Signal (2010) 1.08
How does iron-sulfur cluster coordination regulate the activity of human glutaredoxin 2? Antioxid Redox Signal (2007) 1.08
Thioredoxin and glutaredoxin isoforms. Methods Enzymol (2002) 1.07
Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: potential implications for diagnosis and therapy. J Hematol Oncol (2012) 1.06
Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose. J Biol Chem (2012) 1.06
The contributions of protein disulfide isomerase and its homologues to oxidative protein folding in the yeast endoplasmic reticulum. J Biol Chem (2004) 1.06
Resistance to chemotherapy is associated with fibroblast growth factor receptor 4 up-regulation. Clin Cancer Res (2009) 1.03
Streptomyces spp. contain class Ia and class II ribonucleotide reductases: expression analysis of the genes in vegetative growth. Microbiology (2002) 1.03
Molecular mechanism underlying RAG1/RAG2 synaptic complex formation. J Biol Chem (2009) 1.03
Effect of the vesicular-arbuscular mycorrhizal (VAM) fungus Glomus fasciculatum on the essential oil yield related characters and nutrient acquisition in the crops of different cultivars of menthol mint (Mentha arvensis) under field conditions. Bioresour Technol (2002) 1.03
Prevention of aspiration of nasopharyngeal airway. Anesth Analg (2007) 1.02
Thioredoxin and thioredoxin reductase in relation to reversible S-nitrosylation. Antioxid Redox Signal (2012) 1.01
MicroRNA in pancreatic cancer: pathological, diagnostic and therapeutic implications. Cancer Lett (2009) 1.01
Methane emission from fixed dome biogas plants in hilly and plain regions of northern India. Bioresour Technol (2004) 1.01
Evidence for Ku70/Ku80 association with full-length RAG1. Nucleic Acids Res (2008) 1.00
A conserved cis-proline precludes metal binding by the active site thiolates in members of the thioredoxin family of proteins. Biochemistry (2007) 1.00
Redox regulation of 3'-phosphoadenylylsulfate reductase from Escherichia coli by glutathione and glutaredoxins. J Biol Chem (2003) 1.00
Influence of silver incorporation on the structural and electrical properties of diamond-like carbon thin films. ACS Appl Mater Interfaces (2013) 0.99
High-power and high-temperature THz quantum-cascade lasers based on lens-coupled metal-metal waveguides. Opt Lett (2007) 0.99
Visualization of the compartmentalization of glutathione and protein-glutathione mixed disulfides in cultured cells. FASEB J (2002) 0.98
Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes. Free Radic Biol Med (2011) 0.98
Molecular mapping of functionalities in the solution structure of reduced Grx4, a monothiol glutaredoxin from Escherichia coli. J Biol Chem (2005) 0.98
Surface-emitting distributed feedback terahertz quantum-cascade lasers in metal-metal waveguides. Opt Express (2007) 0.98
Glutaredoxins catalyze the reduction of glutathione by dihydrolipoamide with high efficiency. Biochem Biophys Res Commun (2002) 0.97
The thioredoxin-like protein rod-derived cone viability factor (RdCVFL) interacts with TAU and inhibits its phosphorylation in the retina. Mol Cell Proteomics (2009) 0.96
Penultimate selenocysteine residue replaced by cysteine in thioredoxin reductase from selenium-deficient rat liver. FASEB J (2009) 0.96
Nab-paclitaxel is an active drug in preclinical model of pediatric solid tumors. Clin Cancer Res (2013) 0.96
Truncated thioredoxin (Trx80) exerts unique mitogenic cytokine effects via a mechanism independent of thiol oxido-reductase activity. FEBS Lett (2003) 0.95
Expression pattern of human glutaredoxin 2 isoforms: identification and characterization of two testis/cancer cell-specific isoforms. Antioxid Redox Signal (2008) 0.95
Protein levels of Escherichia coli thioredoxins and glutaredoxins and their relation to null mutants, growth phase, and function. J Biol Chem (2002) 0.94
The role of thioredoxin in the regulation of cellular processes by S-nitrosylation. Biochim Biophys Acta (2011) 0.94
Thioredoxin reductase inhibition by antitumor quinols: a quinol pharmacophore effect correlating to antiproliferative activity. FASEB J (2008) 0.94
Soil properties and crop productivity as influenced by flyash incorporation in soil. Environ Monit Assess (2003) 0.93
Thioredoxin 1 is inactivated due to oxidation induced by peroxiredoxin under oxidative stress and reactivated by the glutaredoxin system. J Biol Chem (2013) 0.93
Characterization of Escherichia coli null mutants for glutaredoxin 2. J Biol Chem (2001) 0.93
Factors affecting the outcome of neuroendoscopy in patients with tuberculous meningitis hydrocephalus: a preliminary study. Surg Neurol (2007) 0.93
Growth and terpenoid indole alkaloid production in Catharanthus roseus hairy root clones in relation to left- and right-termini-linked Ri T-DNA gene integration. Plant Cell Rep (2004) 0.92
The thioredoxin superfamily in oxidative protein folding. Antioxid Redox Signal (2014) 0.92
Bacillus anthracis thioredoxin systems, characterization and role as electron donors for ribonucleotide reductase. J Biol Chem (2012) 0.92
Pearl millet [Pennisetum glaucum (L.) R. Br.] consensus linkage map constructed using four RIL mapping populations and newly developed EST-SSRs. BMC Genomics (2013) 0.92
Catalysis of thiol/disulfide exchange. Glutaredoxin 1 and protein-disulfide isomerase use different mechanisms to enhance oxidase and reductase activities. J Biol Chem (2005) 0.92
Mercury and selenium interaction in vivo: effects on thioredoxin reductase and glutathione peroxidase. Free Radic Biol Med (2011) 0.92
Glutaredoxin 2 reduces both thioredoxin 2 and thioredoxin 1 and protects cells from apoptosis induced by auranofin and 4-hydroxynonenal. Antioxid Redox Signal (2014) 0.92