Published in Neurobiol Dis on July 01, 2004
Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat Rev Neurosci (2010) 5.27
Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitability. J Neurosci (2006) 1.94
Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function. Neuroscience (2011) 1.62
The dichotomy of NMDA receptor signaling. Neuroscientist (2007) 1.61
Coupling of the NMDA receptor to neuroprotective and neurodestructive events. Biochem Soc Trans (2009) 1.50
Anesthesia, calcium homeostasis and Alzheimer's disease. Curr Alzheimer Res (2009) 1.37
Effects of fetal exposure to isoflurane on postnatal memory and learning in rats. Neuropharmacology (2007) 1.31
NMDA antagonist inhibits the extracellular signal-regulated kinase pathway and suppresses cancer growth. Proc Natl Acad Sci U S A (2005) 1.30
Compartmentalized NMDA receptor signalling to survival and death. J Physiol (2007) 1.21
Calcium signaling in synapse-to-nucleus communication. Cold Spring Harb Perspect Biol (2011) 1.12
Microglial displacement of inhibitory synapses provides neuroprotection in the adult brain. Nat Commun (2014) 1.08
Potential mechanism of cell death in the developing rat brain induced by propofol anesthesia. Int J Dev Neurosci (2008) 1.05
Ras homolog enriched in brain (Rheb) enhances apoptotic signaling. J Biol Chem (2010) 1.01
Brain-derived neurotrophic factor prevents phencyclidine-induced apoptosis in developing brain by parallel activation of both the ERK and PI-3K/Akt pathways. Neuropharmacology (2009) 0.97
Cell biology in neuroscience: Death of developing neurons: new insights and implications for connectivity. J Cell Biol (2013) 0.97
BDNF-TrkB signaling and neuroprotection in schizophrenia. Asian J Psychiatr (2012) 0.94
Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains. Drug Alcohol Depend (2007) 0.93
NMDA Neurotransmission Dysfunction in Behavioral and Psychological Symptoms of Alzheimer's Disease. Curr Neuropharmacol (2012) 0.93
Neuropathological sequelae of developmental exposure to antiepileptic and anesthetic drugs. Front Neurol (2012) 0.90
Lovastatin inhibits the extracellular-signal-regulated kinase pathway in immortalized rat brain neuroblasts. Biochem J (2007) 0.89
NMDA receptors promote survival in somatosensory relay nuclei by inhibiting Bax-dependent developmental cell death. Proc Natl Acad Sci U S A (2006) 0.86
Lithium protection of phencyclidine-induced neurotoxicity in developing brain: the role of phosphatidylinositol-3 kinase/Akt and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling pathways. J Pharmacol Exp Ther (2008) 0.85
Limitations of Current GABA Agonists in Neonatal Seizures: Toward GABA Modulation Via the Targeting of Neuronal Cl(-) Transport. Front Neurol (2013) 0.84
Different effects of high- and low-dose phenobarbital on post-stroke seizure suppression and recovery in immature CD1 mice. Epilepsy Res (2011) 0.84
Pediatric neurocritical care. Neurotherapeutics (2012) 0.83
Short term morphine exposure in vitro alters proliferation and differentiation of neural progenitor cells and promotes apoptosis via mu receptors. PLoS One (2014) 0.82
Phencyclidine (PCP)-induced disruption in cognitive performance is gender-specific and associated with a reduction in brain-derived neurotrophic factor (BDNF) in specific regions of the female rat brain. J Mol Neurosci (2010) 0.82
Serum brain-derived neurotrophic factor and nerve growth factor decreased in chronic ketamine abusers. Drug Alcohol Depend (2014) 0.82
Low-level lead exposure triggers neuronal apoptosis in the developing mouse brain. Neurotoxicol Teratol (2011) 0.80
A decrease in phosphorylation of cAMP-response element-binding protein (CREBP) promotes retinal degeneration. Exp Eye Res (2011) 0.80
Striatal development involves a switch in gene expression networks, followed by a myelination event: implications for neuropsychiatric disease. Synapse (2012) 0.78
Inhibition of acetylcholinesterase modulates NMDA receptor antagonist mediated alterations in the developing brain. Int J Mol Sci (2014) 0.76
Reactive Transformation and Increased BDNF Signaling by Hippocampal Astrocytes in Response to MK-801. PLoS One (2015) 0.75
Neuronal survival in the brain: neuron type-specific mechanisms. Cell Death Dis (2017) 0.75
Different effects of isolation-rearing and neonatal MK-801 treatment on attentional modulations of prepulse inhibition of startle in rats. Psychopharmacology (Berl) (2016) 0.75
Ras Activity Tunes the Period and Modulates the Entrainment of the Suprachiasmatic Clock. Front Neurol (2017) 0.75
Dexmedetomidine mitigates isoflurane-induced neurodegeneration in fetal rats during the second trimester of pregnancy. Neural Regen Res (2017) 0.75
Hypoxia-ischemia modifies postsynaptic GluN2B-containing NMDA receptor complexes in the neonatal mouse brain. Exp Neurol (2017) 0.75
Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. Proc Natl Acad Sci U S A (2002) 4.18
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses. Nat Neurosci (2008) 4.04
Anesthesia-induced developmental neuroapoptosis. Does it happen in humans? Anesthesiology (2004) 3.22
Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome. Arthritis Rheum (2010) 2.50
Sedative and anticonvulsant drugs suppress postnatal neurogenesis. Ann Neurol (2008) 2.46
EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase. Mol Cell (2002) 2.31
Antiepileptic drugs and apoptosis in the developing brain. Ann N Y Acad Sci (2003) 2.01
Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain. Brain Res Dev Brain Res (2002) 1.89
Drug-induced apoptotic neurodegeneration in the developing brain. Brain Pathol (2002) 1.85
Do pediatric drugs cause developing neurons to commit suicide? Trends Pharmacol Sci (2004) 1.67
Sulthiame but not levetiracetam exerts neurotoxic effect in the developing rat brain. Exp Neurol (2005) 1.51
Therapeutic doses of topiramate are not toxic to the developing rat brain. Exp Neurol (2004) 1.49
Suppression of the intrinsic apoptosis pathway by synaptic activity. J Neurosci (2010) 1.40
Interleukin Converting Enzyme inhibition impairs kindling epileptogenesis in rats by blocking astrocytic IL-1beta production. Neurobiol Dis (2008) 1.39
Levetiracetam: safety and efficacy in neonatal seizures. Eur J Paediatr Neurol (2010) 1.33
Expression of glutamate receptor subunits in human cancers. Histochem Cell Biol (2009) 1.31
NMDA antagonist inhibits the extracellular signal-regulated kinase pathway and suppresses cancer growth. Proc Natl Acad Sci U S A (2005) 1.30
Erythropoietin protects the developing brain against N-methyl-D-aspartate receptor antagonist neurotoxicity. Neurobiol Dis (2004) 1.23
Regulation of Nerve Growth Factor (NGF) Synthesis in the Rat Central Nervous System: Comparison between the Effects of Interleukin-1 and Various Growth Factors in Astrocyte Cultures and in vivo. Eur J Neurosci (1990) 1.23
The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase. J Biol Chem (2002) 1.23
Effective transfection of cells with multi-shell calcium phosphate-DNA nanoparticles. Biomaterials (2006) 1.21
Oxygen causes cell death in the developing brain. Neurobiol Dis (2004) 1.18
Anticancer agents are potent neurotoxins in vitro and in vivo. Ann Neurol (2004) 1.13
Neurodegeneration in newborn rats following propofol and sevoflurane anesthesia. Neurotox Res (2009) 1.11
The enigma of fetal alcohol neurotoxicity. Ann Med (2002) 1.08
Brief alteration of NMDA or GABAA receptor-mediated neurotransmission has long term effects on the developing cerebral cortex. Mol Cell Proteomics (2008) 1.07
Late-onset motoneuron disease caused by a functionally modified AMPA receptor subunit. Proc Natl Acad Sci U S A (2005) 1.06
The role of matrix metalloproteinases in infant traumatic brain injury. Neurobiol Dis (2006) 1.03
CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly. Cereb Cortex (2012) 1.03
Betulinic acid decreases expression of bcl-2 and cyclin D1, inhibits proliferation, migration and induces apoptosis in cancer cells. Naunyn Schmiedebergs Arch Pharmacol (2006) 1.01
Prevention of hyperoxia-mediated pulmonary inflammation in neonatal rats by caffeine. Eur Respir J (2012) 1.01
Ras homolog enriched in brain (Rheb) enhances apoptotic signaling. J Biol Chem (2010) 1.01
Reactive oxygen species production by blood neutrophils of patients with laryngeal carcinoma and antioxidative enzyme activity in their blood. Acta Oncol (2004) 1.00
Neuronal activation of Ras regulates synaptic connectivity. Eur J Neurosci (2004) 0.99
RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo. Neuro Oncol (2011) 0.99
Exercise can rescue recognition memory impairment in a model with reduced adult hippocampal neurogenesis. Front Behav Neurosci (2010) 0.98
Glutamate receptors in pediatric tumors of the central nervous system. Cancer Biol Ther (2010) 0.98
Corticosteroids reverse cytokine-induced block of survival and differentiation of oligodendrocyte progenitor cells from rats. J Neuroinflammation (2008) 0.98
Kynurenic acid synthesis and kynurenine aminotransferases expression in colon derived normal and cancer cells. Scand J Gastroenterol (2011) 0.97
Silencing of selected glutamate receptor subunits modulates cancer growth. Anticancer Res (2011) 0.97
Pathways leading to apoptotic neurodegeneration following trauma to the developing rat brain. Neurobiol Dis (2002) 0.95
Glutamate antagonists limit tumor growth. Biochem Pharmacol (2002) 0.95
Regrowing the adult brain: NF-κB controls functional circuit formation and tissue homeostasis in the dentate gyrus. PLoS One (2012) 0.94
Erythropoietin protects the developing brain from hyperoxia-induced cell death and proteome changes. Ann Neurol (2008) 0.94
Interaction of inflammation and hyperoxia in a rat model of neonatal white matter damage. PLoS One (2012) 0.93
Neuronal damage after moderate hypoxia and erythropoietin. Neurobiol Dis (2005) 0.93
Estradiol attenuates hyperoxia-induced cell death in the developing white matter. Ann Neurol (2007) 0.93
Caspase-1-processed interleukins in hyperoxia-induced cell death in the developing brain. Ann Neurol (2005) 0.93
Glutamate and its receptors in cancer. J Neural Transm (Vienna) (2014) 0.92
Dose-dependent effects of erythropoietin in propofol anesthetized neonatal rats. Brain Res (2010) 0.91
Structure determination and ligand interactions of the PDZ2b domain of PTP-Bas (hPTP1E): splicing-induced modulation of ligand specificity. J Mol Biol (2003) 0.91
Protection with estradiol in developmental models of apoptotic neurodegeneration. Ann Neurol (2005) 0.91
Effects of repetitive exposure to pain and morphine treatment on the neonatal rat brain. Neonatology (2012) 0.91
Synthesis, characterisation and bioimaging of a fluorescent rhenium-containing PNA bioconjugate. Dalton Trans (2011) 0.90
Neuropathological sequelae of developmental exposure to antiepileptic and anesthetic drugs. Front Neurol (2012) 0.90
PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells. J Cell Sci (2009) 0.90
Fluoxetine inhibits the extracellular signal regulated kinase pathway and suppresses growth of cancer cells. Cancer Biol Ther (2008) 0.90
Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatment. Tumour Biol (2013) 0.89
Erythropoietin modulates autophagy signaling in the developing rat brain in an in vivo model of oxygen-toxicity. Int J Mol Sci (2012) 0.89