Published in Immunology on July 01, 2004
c-Jun N-terminal kinase 1 is required for the development of pulmonary fibrosis. Am J Respir Cell Mol Biol (2008) 1.26
Mitogen activated protein kinase inhibitors: where are we now and where are we going? Ann Rheum Dis (2006) 1.13
Chronic cough due to occupational factors. J Occup Med Toxicol (2006) 0.96
Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation. Am J Physiol Lung Cell Mol Physiol (2014) 0.82
TEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma. J Clin Cell Immunol (2012) 0.77
Differences in MAP kinase phosphorylation in response to mechanical strain in asthmatic fibroblasts. Respir Res (2006) 0.76
TSG-6 secreted by human umbilical cord-MSCs attenuates severe burn-induced excessive inflammation via inhibiting activations of P38 and JNK signaling. Sci Rep (2016) 0.76
Shift work and pathological conditions. J Occup Med Toxicol (2006) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med (1992) 11.90
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A (2001) 11.06
Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies. Immunity (1999) 7.34
Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J Exp Med (1996) 6.34
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. J Mol Med (Berl) (1996) 5.77
Defective T cell differentiation in the absence of Jnk1. Science (1998) 4.40
JNK is involved in signal integration during costimulation of T lymphocytes. Cell (1994) 4.36
c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest (2001) 3.86
Interleukin-5, eosinophils, and disease. Blood (1992) 3.80
c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions. Cell (1996) 3.54
Cytokines in asthma. Thorax (1999) 2.64
Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J Exp Med (1995) 2.52
Regulation of IgG1 and IgE production by interleukin 4. Immunol Rev (1988) 1.80
Role of inflammation in the hyperreactivity of the airways in asthma. Thorax (1986) 1.68
Antiinterleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization. Am J Respir Crit Care Med (1997) 1.62
Signal transduction by the c-Jun N-terminal kinase. Biochem Soc Symp (1999) 1.38
Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells. J Biol Chem (1995) 1.33
TNF initiates E-selectin transcription in human endothelial cells through parallel TRAF-NF-kappa B and TRAF-RAC/CDC42-JNK-c-Jun/ATF2 pathways. J Immunol (1997) 1.31
Activation of Jun N-terminal kinase/stress-activated protein kinase pathway by tumor necrosis factor alpha leads to intercellular adhesion molecule-1 expression. J Biol Chem (1999) 1.18
Allergen-specific Th1 cells counteract efferent Th2 cell-dependent bronchial hyperresponsiveness and eosinophilic inflammation partly via IFN-gamma. J Immunol (2001) 1.16
Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes. J Exp Med (1997) 1.15
Multiple signaling pathways for the activation of JNK in mast cells: involvement of Bruton's tyrosine kinase, protein kinase C, and JNK kinases, SEK1 and MKK7. J Immunol (1998) 1.12
The differential role of extracellular signal-regulated kinases and p38 mitogen-activated protein kinase in eosinophil functions. J Immunol (2000) 1.08
Airway hyperresponsiveness, elevation of serum-specific IgE and activation of T cells following allergen exposure in sensitized Brown-Norway rats. Immunology (1995) 1.03
Activation of C-jun N-terminal kinase/stress-activated protein kinase in primary glial cultures. J Neurosci Res (1996) 0.98
Allergen-induced inflammation and airway epithelial and smooth muscle cell proliferation: role of Jun N-terminal kinase. Br J Pharmacol (2003) 0.92
Inducible nitric oxide synthase after sensitization and allergen challenge of Brown Norway rat lung. Br J Pharmacol (1997) 0.90
Effect of the p38 kinase inhibitor, SB 203580, on allergic airway inflammation in the rat. Br J Pharmacol (2000) 0.90
A novel transcription factor inhibitor, SP100030, inhibits cytokine gene expression, but not airway eosinophilia or hyperresponsiveness in sensitized and allergen-exposed rat. Br J Pharmacol (2001) 0.82
Effect of TEI-9874, an inhibitor of immunoglobulin E production, on allergen-induced asthmatic model in rats. Eur J Pharmacol (2000) 0.77
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J (2013) 8.39
Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med (2005) 6.13
MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res (2009) 3.83
Radiofrequency ablation with or without transcatheter arterial chemoembolization in the treatment of hepatocellular carcinoma: a prospective randomized trial. J Clin Oncol (2012) 3.68
Glucocorticoid resistance in inflammatory diseases. Lancet (2009) 3.57
Extended-spectrum β-lactamase genes of Escherichia coli in chicken meat and humans, The Netherlands. Emerg Infect Dis (2011) 3.37
Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk. Nat Immunol (2011) 3.12
Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. Am J Respir Crit Care Med (2004) 2.81
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med (2005) 2.72
Radiocarbon dating of a very large African baobab. Tree Physiol (2007) 2.59
The West Falmouth oil spill after thirty years: the persistence of petroleum hydrocarbons in marsh sediments. Environ Sci Technol (2002) 2.52
Potential landscape and flux framework of nonequilibrium networks: robustness, dissipation, and coherence of biochemical oscillations. Proc Natl Acad Sci U S A (2008) 2.43
Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma. J Allergy Clin Immunol (2007) 2.43
Expression and activity of histone deacetylases in human asthmatic airways. Am J Respir Crit Care Med (2002) 2.40
catena-Poly[[[pentaaquathulium(III)]-mu-5-sulfonatobenzene-1,3-dicarboxylato] 4,4'-bipyridyl 1.5-solvate hemihydrate]. Acta Crystallogr C (2007) 2.24
Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. Nat Genet (2003) 2.21
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. J Exp Med (2004) 2.19
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. Proc Natl Acad Sci U S A (2002) 2.17
Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat Genet (2003) 2.16
Roles played by chemolipiodolization and embolization in chemoembolization for hepatocellular carcinoma: single-blind, randomized trial. J Natl Cancer Inst (2012) 2.10
Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 2.06
Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2012) 2.06
4-[1-(Hydroxy-imino)ethyl]-N-(4-nitro-benzyl-idene)aniline. Acta Crystallogr Sect E Struct Rep Online (2009) 2.05
Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance. Clin Cancer Res (2009) 2.04
Oxidative stress-induced antibodies to carbonyl-modified protein correlate with severity of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2011) 2.02
Quantifying the Waddington landscape and biological paths for development and differentiation. Proc Natl Acad Sci U S A (2011) 2.00
In vivo post-contrast 1H-MRS evaluation of malignant and benign breast lesions: a meta-analysis. Tumour Biol (2014) 1.99
Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment. Am J Pathol (2003) 1.99
6,6'-Dihydr-oxy-2,2'-[(pentane-1,5-diyl-dioxy)bis-(nitrilo-methyl-idyne)]diphenol. Acta Crystallogr Sect E Struct Rep Online (2008) 1.95
Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy. Am J Respir Crit Care Med (2005) 1.93
Determination of biodiesel blending percentages using natural abundance radiocarbon analysis: testing the accuracy of retail biodiesel blends. Environ Sci Technol (2008) 1.90
c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration. Hepatology (2003) 1.87
p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma. J Allergy Clin Immunol (2002) 1.84
Evolutionary development of the middle ear in Mesozoic therian mammals. Science (2009) 1.82
Update on glucocorticoid action and resistance. J Allergy Clin Immunol (2006) 1.80
Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med (2011) 1.78
MicroRNA-148/152 impair innate response and antigen presentation of TLR-triggered dendritic cells by targeting CaMKIIα. J Immunol (2010) 1.77
Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma. Proc Natl Acad Sci U S A (2009) 1.77
Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes. FASEB J (2004) 1.76
The potential landscape of genetic circuits imposes the arrow of time in stem cell differentiation. Biophys J (2010) 1.76
The toxicity of cadmium and resulting hazards for human health. J Occup Med Toxicol (2006) 1.72
Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase. Lancet (2004) 1.71
Satellite methods underestimate indirect climate forcing by aerosols. Proc Natl Acad Sci U S A (2011) 1.70
p38 mitogen-activated protein kinase-γ inhibition by long-acting β2 adrenergic agonists reversed steroid insensitivity in severe asthma. Mol Pharmacol (2011) 1.70
Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough. Am J Respir Crit Care Med (2004) 1.66
The basic helix-loop-helix transcription factor MYC2 directly represses PLETHORA expression during jasmonate-mediated modulation of the root stem cell niche in Arabidopsis. Plant Cell (2011) 1.65
Increased p21(CIP1/WAF1) and B cell lymphoma leukemia-x(L) expression and reduced apoptosis in alveolar macrophages from smokers. Am J Respir Crit Care Med (2002) 1.65
Pan-neurotrophin receptor p75 contributes to neuronal hyperreactivity and airway inflammation in a murine model of experimental asthma. Am J Respir Cell Mol Biol (2003) 1.65
Effects of glucocorticoids on gene transcription. Eur J Pharmacol (2004) 1.61
A new azhdarchoid pterosaur from the Lower Cretaceous of China and its implications for pterosaur phylogeny and evolution. Naturwissenschaften (2008) 1.61
Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice. Am J Respir Crit Care Med (2009) 1.59
A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification. Mol Pharmacol (2004) 1.59
Effects of carrier pulse rate and stimulation site on modulation detection by subjects with cochlear implants. J Acoust Soc Am (2007) 1.58
Dietary genistein inhibits metastasis of human prostate cancer in mice. Cancer Res (2008) 1.57
IL4R alpha mutations are associated with asthma exacerbations and mast cell/IgE expression. Am J Respir Crit Care Med (2006) 1.57
Transgenic study of the function of chymase in heart remodeling. J Hypertens (2002) 1.55
Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma. Am J Respir Crit Care Med (2004) 1.53
Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma. J Clin Invest (2011) 1.52
Clinical definition of COPD exacerbations and classification of their severity. South Med J (2009) 1.52
Rescue treatment in asthma. More than as-needed bronchodilation. Chest (2009) 1.52
6,6'-Dihydr-oxy-2,2'-[(butane-1,4-diyldi-oxy)bis-(nitrilo-methyl-idyne)]diphenol. Acta Crystallogr Sect E Struct Rep Online (2008) 1.51
Identification of a new Neisseria meningitidis serogroup C clone from Anhui province, China. Lancet (2006) 1.50
Down-regulated in adenoma mediates apical Cl-/HCO3- exchange in rabbit, rat, and human duodenum. Gastroenterology (2002) 1.47
NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription. J Immunol (2006) 1.46
Protection from the 2009 H1N1 pandemic influenza by an antibody from combinatorial survivor-based libraries. PLoS Pathog (2010) 1.46
Across-site variation in detection thresholds and maximum comfortable loudness levels for cochlear implants. J Assoc Res Otolaryngol (2003) 1.45
Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI). Thorax (2010) 1.45
The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity. J Biol Chem (2002) 1.45
A one-dimensional zigzag coordination polymer: catena-poly[[diaquapyridinenickel(II)]-mu-pyridine-2,3-dicarboxylato-kappa3N,O2:O3]. Acta Crystallogr C (2003) 1.45
Differential diagnosis between hepatic metastases and benign focal lesions using DWI with parallel acquisition technique: a meta-analysis. Tumour Biol (2014) 1.44
MicroRNA expression profiling in mild asthmatic human airways and effect of corticosteroid therapy. PLoS One (2009) 1.44
Doped graphene sheets as anode materials with superhigh rate and large capacity for lithium ion batteries. ACS Nano (2011) 1.43
Gender differences in efficacy of primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction. Chin Med J (Engl) (2008) 1.42
Risk factors for perioperative major cardiac events in Chinese elderly patients with coronary heart disease undergoing noncardiac surgery. Chin Med J (Engl) (2013) 1.42
Models of chronic obstructive pulmonary disease. Respir Res (2004) 1.42
Dishing the dirt on asthma: What we can learn from poor hygiene. Biologics (2007) 1.40
Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells. Cancer Res (2005) 1.40
Inhaled corticosteroids as combination therapy with beta-adrenergic agonists in airways disease: present and future. Eur J Clin Pharmacol (2009) 1.40
Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer. BMC Cancer (2012) 1.39
Supraglottic jet oxygenation and ventilation reduces desaturation during bronchoscopy under moderate to deep sedation with propofol and remifentanil: A randomised controlled clinical trial. Eur J Anaesthesiol (2021) 1.39
New targets for drug development in asthma. Lancet (2008) 1.38
Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients. J Allergy Clin Immunol (2004) 1.38
Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases. Blood (2009) 1.37
Surgical resection of limited disease small cell lung cancer in the new era of platinum chemotherapy: Its time has come. J Thorac Cardiovasc Surg (2005) 1.37
Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response. Cell Microbiol (2009) 1.36
Inhibition of cell proliferation and cell cycle progression by specific inhibition of basal JNK activity: evidence that mitotic Bcl-2 phosphorylation is JNK-independent. J Biol Chem (2004) 1.33
Cyclic AMP plays a critical role in C3a-receptor-mediated regulation of dendritic cells in antigen uptake and T-cell stimulation. Blood (2008) 1.33
CDKL5, a protein associated with rett syndrome, regulates neuronal morphogenesis via Rac1 signaling. J Neurosci (2010) 1.33
Differential roles of NMDA receptor subtypes in ischemic neuronal cell death and ischemic tolerance. Stroke (2008) 1.32
Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain. Eur J Neurosci (2005) 1.32
Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectin glycoarray and lectin blot. J Proteome Res (2008) 1.29
Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease. J Pharmacol Exp Ther (2006) 1.29
How do corticosteroids work in asthma? Ann Intern Med (2003) 1.29
Relative importance of temporal envelope and fine structure in lexical-tone perception. J Acoust Soc Am (2003) 1.28
Determinants of host susceptibility in aggressive periodontitis. Periodontol 2000 (2007) 1.28