Use of dynamic combinatorial chemistry for the identification of covalently appended residues that stabilize oligonucleotide complexes.

PubWeight™: 0.87‹?›

🔗 View Article (PMID 15199562)

Published in Angew Chem Int Ed Engl on June 14, 2004

Authors

Anthony Bugaut1, Jean-Jacques Toulmé, Bernard Rayner

Author Affiliations

1: INSERM U386, Université Victor Segalen Bordeaux 2, 146, rue Léo Saignat, 33076 Bordeaux Cedex, France.

Articles by these authors

A boost for the emerging field of RNA nanotechnology. ACS Nano (2011) 1.17

Antisense oligonucleotides targeted to the domain IIId of the hepatitis C virus IRES compete with 40S ribosomal subunit binding and prevent in vitro translation. Nucleic Acids Res (2003) 1.06

Aptamers targeted to an RNA hairpin show improved specificity compared to that of complementary oligonucleotides. Biochemistry (2006) 1.02

Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex. Proc Natl Acad Sci U S A (2008) 0.99

LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1. Nucleic Acids Res (2004) 0.97

Apical loop-internal loop interactions: a new RNA-RNA recognition motif identified through in vitro selection against RNA hairpins of the hepatitis C virus mRNA. Biochemistry (2002) 0.97

Selective inhibitory DNA aptamers of the human RNase H1. Nucleic Acids Res (2003) 0.95

Aptamers: a new class of oligonucleotides in the drug discovery pipeline? Curr Opin Pharmacol (2009) 0.93

Loop-loop interaction of HIV-1 TAR RNA with N3'-->P5' deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription. Proc Natl Acad Sci U S A (2002) 0.91

2'-O-methyl-RNA hairpins generate loop-loop complexes and selectively inhibit HIV-1 Tat-mediated transcription. Biochemistry (2002) 0.90

Endogenous expression of an anti-TAR aptamer reduces HIV-1 replication. RNA Biol (2006) 0.87

SELEX and dynamic combinatorial chemistry interplay for the selection of conjugated RNA aptamers. Org Biomol Chem (2006) 0.87

NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamer. Nucleic Acids Res (2007) 0.86

Determinants of apical loop-internal loop RNA-RNA interactions involving the HCV IRES. Biochem Biophys Res Commun (2004) 0.85

LNA derivatives of a kissing aptamer targeted to the trans-activating responsive RNA element of HIV-1. Blood Cells Mol Dis (2007) 0.83

Hexitol nucleic acid-containing aptamers are efficient ligands of HIV-1 TAR RNA. Biochemistry (2005) 0.83

Nucleic acids targeted to drugs: SELEX against a quadruplex ligand. Biochimie (2011) 0.83

Tricyclo-DNA containing oligonucleotides as steric block inhibitors of human immunodeficiency virus type 1 tat-dependent trans-activation and HIV-1 infectivity. Oligonucleotides (2007) 0.82

Systematic screening of LNA/2'-O-methyl chimeric derivatives of a TAR RNA aptamer. FEBS Lett (2007) 0.82

In vitro selection of RNA aptamers derived from a genomic human library against the TAR RNA element of HIV-1. Biochemistry (2009) 0.82

A functional selection of viral genetic elements in cultured cells to identify hepatitis C virus RNA translation inhibitors. Nucleic Acids Res (2008) 0.81

In vitro selection of DNA aptamers against the HIV-1 TAR RNA hairpin. Antisense Nucleic Acid Drug Dev (2002) 0.81

Deciphering aromatic oligoamide foldamer-DNA interactions. Angew Chem Int Ed Engl (2011) 0.80

HAPIscreen, a method for high-throughput aptamer identification. J Nanobiotechnology (2011) 0.80

Bimodal loop-loop interactions increase the affinity of RNA aptamers for HIV-1 RNA structures. Biochemistry (2006) 0.80

In vitro selection procedures for identifying DNA and RNA aptamers targeted to nucleic acids and proteins. Methods Mol Biol (2005) 0.79

(99m)Tc-MAG3-aptamer for imaging human tumors associated with high level of matrix metalloprotease-9. Bioconjug Chem (2012) 0.79

Surface plasmon resonance investigation of RNA aptamer-RNA ligand interactions. Methods Mol Biol (2011) 0.78

A mirror-image tetramolecular DNA quadruplex. Chem Commun (Camb) (2011) 0.77

Anti-HIV activity of steric block oligonucleotides. Ann N Y Acad Sci (2006) 0.77

Aptamers as imaging agents. Expert Opin Med Diagn (2010) 0.77

L-nucleotides and 8-methylguanine of d(C1m8G2C3G4C5LG6LC7G8C9G10)2 act cooperatively to promote a left-handed helix under physiological salt conditions. Nucleic Acids Res (2003) 0.77

Regulating mRNA translation with a kiss. Nucleic Acids Symp Ser (Oxf) (2008) 0.76

Aptamers targeting RNA molecules. Methods Mol Biol (2009) 0.76

Advances in binder identification and characterisation: the case of oligonucleotide aptamers. N Biotechnol (2011) 0.76

Riboswitches based on kissing complexes for the detection of small ligands. Angew Chem Int Ed Engl (2014) 0.76

An improved design of the kissing complex-based aptasensor for the detection of adenosine. Anal Bioanal Chem (2015) 0.75

Inhibition of pre-mRNA splicing by a synthetic Blom7α-interacting small RNA. PLoS One (2012) 0.75

Formation of N-branched oligonucleotides as by-products in solid-phase oligonucleotide synthesis. Oligonucleotides (2006) 0.75

Aptamer-mediated nanoparticle interactions: from oligonucleotide-protein complexes to SELEX screens. Methods Mol Biol (2015) 0.75

Encapsidation of RNA-polyelectrolyte complexes with amphiphilic block copolymers: toward a new self-assembly route. J Am Chem Soc (2012) 0.75

[Hommage to Professor Claude Hélène]. Bull Cancer (2003) 0.75

Comparative studies of tricyclo-DNA- and LNA-containing oligonucleotides as inhibitors of HIV-1 gene expression. Nucleosides Nucleotides Nucleic Acids (2007) 0.75

2'-O-Appended polyamines that increase triple-helix-forming oligonucleotide affinity are selected by dynamic combinatorial chemistry. Chembiochem (2010) 0.75

Nucleic acid aptamers. Methods (2016) 0.75