Published in Nucleic Acids Res on July 09, 2008
RNA structure: new messages in translation, replication and disease. Workshop on the role of RNA structures in the translation of viral and cellular RNAs. EMBO Rep (2009) 0.80
The characteristics of rare codon clusters in the genome and proteins of hepatitis C virus; a bioinformatics look. Middle East J Dig Dis (2014) 0.79
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med (2005) 21.56
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science (2005) 16.84
Replication of hepatitis C virus. Nat Rev Microbiol (2007) 8.31
Internal ribosome entry sites in eukaryotic mRNA molecules. Genes Dev (2001) 7.60
Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations. J Virol (2001) 6.71
Course and outcome of hepatitis C. Hepatology (2002) 6.51
An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A. J Biol Chem (2001) 3.91
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Proc Natl Acad Sci U S A (1999) 3.77
Sequences in the 5' nontranslated region of hepatitis C virus required for RNA replication. J Virol (2001) 3.43
The hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane protein. Virology (2001) 3.25
A phylogenetically conserved stem-loop structure at the 5' border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation. J Virol (1999) 3.13
Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A. J Biol Chem (2004) 2.71
Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains. Proc Natl Acad Sci U S A (1996) 2.66
Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus. J Virol (2006) 1.99
Cloning mammalian genes by expression selection of genetic suppressor elements: association of kinesin with drug resistance and cell immortalization. Proc Natl Acad Sci U S A (1994) 1.93
Internal ribosome entry site-mediated translation in hepatitis C virus replication. Curr Top Microbiol Immunol (2000) 1.78
Interaction of hepatitis C virus core protein with viral sense RNA and suppression of its translation. J Virol (1999) 1.63
Extension of the replicative life span of human diploid fibroblasts by inhibition of the p33ING1 candidate tumor suppressor. Mol Cell Biol (1997) 1.37
Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach. Proc Natl Acad Sci U S A (2000) 1.32
Isolation of dominant negative mutants and inhibitory antisense RNA sequences by expression selection of random DNA fragments. Nucleic Acids Res (1992) 1.23
Autogenous translational inhibition of core protein: implication for switch from translation to RNA replication in hepatitis C virus. Virology (2002) 1.17
The regulation of hepatitis C virus (HCV) internal ribosome-entry site-mediated translation by HCV replicons and nonstructural proteins. J Gen Virol (2003) 1.14
Hepatitis C virus NS4A and NS4B proteins suppress translation in vivo. J Med Virol (2002) 1.12
Identification of new drug sensitivity genes using genetic suppressor elements: protein arginine N-methyltransferase mediates cell sensitivity to DNA-damaging agents. Cancer Res (2003) 1.09
Regulation of host cell translation by viruses and effects on cell function. Curr Opin Microbiol (2000) 1.05
Amino acids 1-20 of the hepatitis C virus (HCV) core protein specifically inhibit HCV IRES-dependent translation in HepG2 cells, and inhibit both HCV IRES- and cap-dependent translation in HuH7 and CV-1 cells. J Gen Virol (2003) 1.00
Hepatitis C virus core protein acts as a trans-modulating factor on internal translation initiation of the viral RNA. J Biol Chem (2005) 0.97
Hepatitis C virus (HCV) NS5A protein downregulates HCV IRES-dependent translation. J Gen Virol (2005) 0.92
Identification of cell surface targets for HIV-1 therapeutics using genetic screens. Virology (2004) 0.87
A combination of genetic suppressor elements produces resistance to drugs inhibiting DNA replication. Somat Cell Mol Genet (1999) 0.83
Genetic suppressor elements in the characterization and identification of tumor suppressor genes. Methods Mol Biol (2003) 0.79
The primary transcriptome of the major human pathogen Helicobacter pylori. Nature (2010) 7.70
Hepatitis C virus entry depends on clathrin-mediated endocytosis. J Virol (2006) 3.33
Role of N-linked glycans in the functions of hepatitis C virus envelope glycoproteins. J Virol (2005) 2.19
Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus. J Virol (2006) 1.99
Subcellular localization and topology of the p7 polypeptide of hepatitis C virus. J Virol (2002) 1.89
The CD81 partner EWI-2wint inhibits hepatitis C virus entry. PLoS One (2008) 1.86
Silibinin and related compounds are direct inhibitors of hepatitis C virus RNA-dependent RNA polymerase. Gastroenterology (2009) 1.69
Robust production of infectious viral particles in Huh-7 cells by introducing mutations in hepatitis C virus structural proteins. J Gen Virol (2007) 1.69
Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status. Int J Cancer (2002) 1.53
Topological changes in the transmembrane domains of hepatitis C virus envelope glycoproteins. EMBO J (2002) 1.52
Identification of GBF1 as a cellular factor required for hepatitis C virus RNA replication. J Virol (2009) 1.43
Role of N-linked glycans in the functions of hepatitis C virus envelope proteins incorporated into infectious virions. J Virol (2010) 1.41
alpha(v) integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells. Oncogene (2003) 1.36
(-)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry. Hepatology (2012) 1.34
Serum-derived hepatitis C virus infection of primary human hepatocytes is tetraspanin CD81 dependent. J Virol (2007) 1.33
Cyanovirin-N inhibits hepatitis C virus entry by binding to envelope protein glycans. J Biol Chem (2006) 1.32
A boost for the emerging field of RNA nanotechnology. ACS Nano (2011) 1.17
Altered adhesion properties and alphav integrin expression in a cisplatin-resistant human ovarian carcinoma cell line. Int J Cancer (2002) 1.16
Griffithsin has antiviral activity against hepatitis C virus. Antimicrob Agents Chemother (2011) 1.14
A promoter activity is present in the DNA sequence corresponding to the hepatitis C virus 5' UTR. Nucleic Acids Res (2003) 1.11
Role for DNA damage signaling in pulmonary arterial hypertension. Circulation (2013) 1.11
Inhibition of hepatitis C virus infection in cell culture by small interfering RNAs. Mol Ther (2007) 1.09
HIV-1 resistance patterns to integrase inhibitors in antiretroviral-experienced patients with virological failure on raltegravir-containing regimens. J Antimicrob Chemother (2010) 1.08
Riboproteomic analysis of polypeptides interacting with the internal ribosome-entry site element of foot-and-mouth disease viral RNA. Proteomics (2008) 1.06
Antisense oligonucleotides targeted to the domain IIId of the hepatitis C virus IRES compete with 40S ribosomal subunit binding and prevent in vitro translation. Nucleic Acids Res (2003) 1.06
Ceramide enrichment of the plasma membrane induces CD81 internalization and inhibits hepatitis C virus entry. Cell Microbiol (2007) 1.04
Aptamers targeted to an RNA hairpin show improved specificity compared to that of complementary oligonucleotides. Biochemistry (2006) 1.02
Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex. Proc Natl Acad Sci U S A (2008) 0.99
Helicobacter pylori interferes with an embryonic stem cell micro RNA cluster to block cell cycle progression. Silence (2011) 0.98
Identification of basic amino acids at the N-terminal end of the core protein that are crucial for hepatitis C virus infectivity. J Virol (2010) 0.98
LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1. Nucleic Acids Res (2004) 0.97
Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion. Hepatology (2012) 0.97
Apical loop-internal loop interactions: a new RNA-RNA recognition motif identified through in vitro selection against RNA hairpins of the hepatitis C virus mRNA. Biochemistry (2002) 0.97
Molecular basis of differential target regulation by miR-96 and miR-182: the Glypican-3 as a model. Nucleic Acids Res (2011) 0.97
Selective inhibitory DNA aptamers of the human RNase H1. Nucleic Acids Res (2003) 0.95
Glycosylation of the hepatitis C virus envelope protein E1 occurs posttranslationally in a mannosylphosphoryldolichol-deficient CHO mutant cell line. Glycobiology (2002) 0.95
Serum amyloid A has antiviral activity against hepatitis C virus by inhibiting virus entry in a cell culture system. Hepatology (2006) 0.94
Aptamers: a new class of oligonucleotides in the drug discovery pipeline? Curr Opin Pharmacol (2009) 0.93
Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC. J Biol Chem (2007) 0.93
Transposase-transposase interactions in MOS1 complexes: a biochemical approach. J Mol Biol (2010) 0.91
Loop-loop interaction of HIV-1 TAR RNA with N3'-->P5' deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription. Proc Natl Acad Sci U S A (2002) 0.91
K65R in subtype C HIV-1 isolates from patients failing on a first-line regimen including d4T or AZT: comparison of Sanger and UDP sequencing data. PLoS One (2012) 0.91
Targeting the production of oncogenic microRNAs with multimodal synthetic small molecules. ACS Chem Biol (2014) 0.90
Inhibition of hepatitis C virus (HCV) RNA polymerase by DNA aptamers: mechanism of inhibition of in vitro RNA synthesis and effect on HCV-infected cells. Antimicrob Agents Chemother (2008) 0.90
2'-O-methyl-RNA hairpins generate loop-loop complexes and selectively inhibit HIV-1 Tat-mediated transcription. Biochemistry (2002) 0.90
Resistance mutations and CTL epitopes in archived HIV-1 DNA of patients on antiviral treatment: toward a new concept of vaccine. PLoS One (2013) 0.88
Effect of ribavirin on the hepatitis C virus (JFH-1) and its correlation with interferon sensitivity. Antivir Ther (2007) 0.88
Detection of low-frequency HIV type 1 reverse transcriptase drug resistance mutations by ultradeep sequencing in naive HIV type 1-infected individuals. AIDS Res Hum Retroviruses (2013) 0.87
Additional glycosylation within a specific hypervariable region of subtype 3a of hepatitis C virus protects against virus neutralization. J Infect Dis (2013) 0.87
Modulating viral gene expression by aptamers to RNA structures. Biol Cell (2003) 0.87
Endogenous expression of an anti-TAR aptamer reduces HIV-1 replication. RNA Biol (2006) 0.87
Cellular uptake of ODNs in HIV-1 human-infected cells: a role for viral particles in DNA delivery? Oligonucleotides (2007) 0.87
Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3'-end of virus minus-strand RNA. FEBS J (2005) 0.87
Use of dynamic combinatorial chemistry for the identification of covalently appended residues that stabilize oligonucleotide complexes. Angew Chem Int Ed Engl (2004) 0.87
Helicobacter pylori initiates a mesenchymal transition through ZEB1 in gastric epithelial cells. PLoS One (2013) 0.87
Characterization of the expression of the hepatitis C virus F protein. J Gen Virol (2003) 0.87
SELEX and dynamic combinatorial chemistry interplay for the selection of conjugated RNA aptamers. Org Biomol Chem (2006) 0.87
The association of CD81 with tetraspanin-enriched microdomains is not essential for Hepatitis C virus entry. BMC Microbiol (2009) 0.87
Hepatitis C virus genetic variability in 52 human immunodeficiency virus-coinfected patients. J Med Virol (2003) 0.86
Dynamic and rapid changes in viral quasispecies by UDPS in chronic hepatitis C patients receiving telaprevir-based therapy. Antivir Ther (2013) 0.86
NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamer. Nucleic Acids Res (2007) 0.86
Inflammatory cytokine and microRNA responses of primary human dendritic cells cultured with Helicobacter pylori strains. Front Microbiol (2013) 0.86
Two crucial early steps in RNA synthesis by the hepatitis C virus polymerase involve a dual role of residue 405. J Virol (2012) 0.86
Determinants of apical loop-internal loop RNA-RNA interactions involving the HCV IRES. Biochem Biophys Res Commun (2004) 0.85
The antimalarial ferroquine is an inhibitor of hepatitis C virus. Hepatology (2013) 0.84
Direct evidence for RNA-RNA interactions at the 3' end of the Hepatitis C virus genome using surface plasmon resonance. RNA (2013) 0.83
Cell culture systems for the hepatitis C virus. World J Gastroenterol (2007) 0.83
LNA derivatives of a kissing aptamer targeted to the trans-activating responsive RNA element of HIV-1. Blood Cells Mol Dis (2007) 0.83
Hexitol nucleic acid-containing aptamers are efficient ligands of HIV-1 TAR RNA. Biochemistry (2005) 0.83
Natural selection of adaptive mutations in non-structural genes increases trans-encapsidation of hepatitis C virus replicons lacking envelope protein genes. J Gen Virol (2013) 0.83
Glycosyl-nucleoside-lipid based supramolecular assembly as a nanostructured material with nucleic acid delivery capabilities. Chem Commun (Camb) (2009) 0.83
Development and biological assessment of fully water-soluble helical aromatic amide foldamers. Angew Chem Int Ed Engl (2007) 0.83
Lipid-conjugated oligonucleotides via "click chemistry" efficiently inhibit hepatitis C virus translation. J Med Chem (2008) 0.83
Nucleic acids targeted to drugs: SELEX against a quadruplex ligand. Biochimie (2011) 0.83
Identification of interactions in the E1E2 heterodimer of hepatitis C virus important for cell entry. J Biol Chem (2011) 0.82
Selection of DNA aptamers that bind the RNA-dependent RNA polymerase of hepatitis C virus and inhibit viral RNA synthesis in vitro. Oligonucleotides (2003) 0.82
Seven nucleotide changes characteristic of the hepatitis C virus genotype 3 5' untranslated region: correlation with reduced in vitro replication. J Gen Virol (2008) 0.82
In vitro selection of RNA aptamers derived from a genomic human library against the TAR RNA element of HIV-1. Biochemistry (2009) 0.82
Tricyclo-DNA containing oligonucleotides as steric block inhibitors of human immunodeficiency virus type 1 tat-dependent trans-activation and HIV-1 infectivity. Oligonucleotides (2007) 0.82
Systematic screening of LNA/2'-O-methyl chimeric derivatives of a TAR RNA aptamer. FEBS Lett (2007) 0.82
Variability and recombination of clinical human cytomegalovirus strains from transplantation recipients. J Clin Virol (2010) 0.81
A hepatitis C virus (HCV) NS3/4A protease-dependent strategy for the identification and purification of HCV-infected cells. J Gen Virol (2006) 0.81
Permissivity of primary human hepatocytes and different hepatoma cell lines to cell culture adapted hepatitis C virus. PLoS One (2013) 0.81