Published in J Biol Chem on June 18, 2004
Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphisms in Chinese population. Pharmacogenet Genomics (2009) 1.06
Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2'-deoxyuridine-5'-monophosphate on ABCC11 in silico models. BMC Struct Biol (2013) 0.76
Transverse and tangential orientation of predicted transmembrane fragments 4 and 10 from the human multidrug resistance protein (hMRP1/ABCC1) in membrane mimics. Eur Biophys J (2011) 0.75
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. Neuron (2004) 4.21
Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Toxicol Appl Pharmacol (2005) 3.34
Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins. Physiol Rev (2006) 3.22
Presenilins are essential for regulating neurotransmitter release. Nature (2009) 2.39
The yak genome and adaptation to life at high altitude. Nat Genet (2012) 2.34
Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice. Neuron (2004) 2.14
Homeostatic regulation of AMPA receptor expression at single hippocampal synapses. Proc Natl Acad Sci U S A (2008) 1.85
Transport of glutathione and glutathione conjugates by MRP1. Trends Pharmacol Sci (2006) 1.66
Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice. J Neurosci (2005) 1.53
Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required. J Biol Chem (2004) 1.52
Materials science: Share corrosion data. Nature (2015) 1.50
CFTR directly mediates nucleotide-regulated glutathione flux. EMBO J (2003) 1.45
Biodistribution and toxicity of intravenously administered silica nanoparticles in mice. Arch Toxicol (2010) 1.42
Na⁺/H⁺ exchanger regulatory factor 3 is critical for multidrug resistance protein 4-mediated drug efflux in the kidney. J Am Soc Nephrol (2014) 1.41
Substrate recognition and transport by multidrug resistance protein 1 (ABCC1). FEBS Lett (2005) 1.38
Plasmodium falciparum multidrug resistance protein 1 and artemisinin-based combination therapy in Africa. J Infect Dis (2009) 1.26
Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1). Pharmacogenet Genomics (2005) 1.17
Mammalian multidrug-resistance proteins (MRPs). Essays Biochem (2011) 1.11
A novel human Fab antibody for Trop2 inhibits breast cancer growth in vitro and in vivo. Int J Cancer (2013) 1.02
A superior low-cost cathode for a Na-ion battery. Angew Chem Int Ed Engl (2013) 1.01
Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4. Cancer Res (2008) 1.01
A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance. Pharmacogenetics (2002) 1.00
Inhibition of proliferation and differentiation of mesenchymal stem cells by carboxylated carbon nanotubes. ACS Nano (2010) 1.00
Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1). Biochem Biophys Res Commun (2007) 0.98
Site-specific fluorescent labeling of nascent proteins on the translating ribosome. J Am Chem Soc (2011) 0.98
Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1). Biochemistry (2003) 0.97
Role of the NH2-terminal membrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and trafficking. Mol Biol Cell (2005) 0.95
A human Fab-based immunoconjugate specific for the LMP1 extracellular domain inhibits nasopharyngeal carcinoma growth in vitro and in vivo. Mol Cancer Ther (2011) 0.95
Synthesis, characterization, photophysical and oxygen-sensing properties of a novel europium(III) complex. Spectrochim Acta A Mol Biomol Spectrosc (2010) 0.95
Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux. PLoS One (2012) 0.93
Discovery and in vivo evaluation of (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and related PI3Kδ inhibitors for inflammation and autoimmune disease. J Med Chem (2014) 0.93
Functional interactions between nucleotide binding domains and leukotriene C4 binding sites of multidrug resistance protein 1 (ABCC1). Mol Pharmacol (2005) 0.92
Diagnosis and surgical treatment of esophageal leiomyoma. Zhonghua Zhong Liu Za Zhi (2002) 0.92
Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1). J Biol Chem (2005) 0.91
Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1). J Biol Chem (2003) 0.91
The heat shock protein HSP70 and heat shock cognate protein HSC70 contribute to antimony tolerance in the protozoan parasite leishmania. Cell Stress Chaperones (2004) 0.91
Ambient Temperature, Ullmann-like Reductive Coupling of Aryl, Heteroaryl, and Alkenyl Halides. J Org Chem (1997) 0.91
Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffold. J Med Chem (2008) 0.91
Synthesis, structural investigations, hydrogen-deuterium exchange studies, and molecular modeling of conformationally stablilized aromatic oligoamides. J Am Chem Soc (2010) 0.91
Folding of a helix at room temperature is critically aided by electrostatic polarization of intraprotein hydrogen bonds. J Am Chem Soc (2010) 0.90
Mutations of charged amino acids in or near the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein MRP1 (ABCC1). Mol Pharmacol (2004) 0.90
Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells. Pharmazie (2005) 0.90
Identification of regions required for apical membrane localization of human multidrug resistance protein 2. Mol Pharmacol (2008) 0.90
MRP1 polymorphisms associated with citalopram response in patients with major depression. J Clin Psychopharmacol (2010) 0.89
Nitric oxide protects against mitochondrial permeabilization induced by glutathione depletion: role of S-nitrosylation? Biochem Biophys Res Commun (2005) 0.89
Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters. Pharmacogenet Genomics (2005) 0.89
Enhanced extracellular production of α-amylase in Bacillus subtilis by optimization of regulatory elements and over-expression of PrsA lipoprotein. Biotechnol Lett (2014) 0.89
Involvement of NHERF1 in apical membrane localization of MRP4 in polarized kidney cells. Biochem Biophys Res Commun (2008) 0.88
3-amino-7-phthalazinylbenzoisoxazoles as a novel class of potent, selective, and orally available inhibitors of p38alpha mitogen-activated protein kinase. J Med Chem (2008) 0.88
Expression and function of human MRP1 (ABCC1) is dependent on amino acids in cytoplasmic loop 5 and its interface with nucleotide binding domain 2. J Biol Chem (2010) 0.88
Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity. J Biol Chem (2002) 0.88
Increased expression of Trop2 correlates with poor survival in extranodal NK/T cell lymphoma, nasal type. Virchows Arch (2013) 0.88
Antimicrobial activities of endophytic fungi isolated from Ophiopogon japonicus (Liliaceae). BMC Complement Altern Med (2012) 0.87
Epilepsy gene LGI1 regulates postnatal developmental remodeling of retinogeniculate synapses. J Neurosci (2012) 0.87
A fluorescent glycolipid-binding peptide probe traces cholesterol dependent microdomain-derived trafficking pathways. PLoS One (2008) 0.86
Lipid production of Chlorella vulgaris cultured in artificial wastewater medium. Bioresour Technol (2011) 0.86
Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. fusion [corrected] inhibition. Biochem Biophys Res Commun (2007) 0.86
Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1. J Biol Chem (2002) 0.86
Functional expression of the human breast cancer resistance protein in Pichia pastoris. Biochem Biophys Res Commun (2004) 0.86
Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas. Biochem Pharmacol (2004) 0.85
Open-shell ground state of polyacenes: a valence bond study. J Phys Chem A (2009) 0.85
High-content screening analysis of the p38 pathway: profiling of structurally related p38alpha kinase inhibitors using cell-based assays. Assay Drug Dev Technol (2006) 0.85
ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript. Pharmacogenet Genomics (2011) 0.85
Structure-function analysis of the highly conserved charged residues of the membrane protein FT1, the main folic acid transporter of the protozoan parasite Leishmania. Biochem Pharmacol (2009) 0.85
Residues responsible for the asymmetric function of the nucleotide binding domains of multidrug resistance protein 1. Biochemistry (2008) 0.85
Colored image produced with guided-mode resonance filter array. Opt Lett (2011) 0.85
ABCA1 mediates high-affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cells. Am J Physiol Cell Physiol (2006) 0.85
Topoisomerase II binds importin alpha isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells. Exp Cell Res (2006) 0.85
Well-aligned arrays of CuO nanoplatelets. J Phys Chem B (2006) 0.84
Comparison of survival and quality of life of hepatectomy and thrombectomy using total hepatic vascular exclusion and chemotherapy alone in patients with hepatocellular carcinoma and tumor thrombi in the inferior vena cava and hepatic vein. Eur J Gastroenterol Hepatol (2012) 0.84
Eaf1 and Eaf2 negatively regulate canonical Wnt/β-catenin signaling. Development (2013) 0.84
Receptors and signaling pathway underlying relaxations to isoprostanes in canine and porcine airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2002) 0.84
Identification of the structural and functional boundaries of the multidrug resistance protein 1 cytoplasmic loop 3. Biochemistry (2003) 0.84
Transmembrane helix 11 of multidrug resistance protein 1 (MRP1/ABCC1): identification of polar amino acids important for substrate specificity and binding of ATP at nucleotide binding domain 1. Biochemistry (2004) 0.83