Published in Cell on June 25, 2004
Cell wall integrity signaling in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (2005) 5.46
A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size. Genes Dev (2004) 5.08
The Forkhead transcription factor Hcm1 regulates chromosome segregation genes and fills the S-phase gap in the transcriptional circuitry of the cell cycle. Genes Dev (2006) 3.58
Positive feedback of G1 cyclins ensures coherent cell cycle entry. Nature (2008) 3.32
The size of the nucleus increases as yeast cells grow. Mol Biol Cell (2007) 2.55
Control of cell cycle transcription during G1 and S phases. Nat Rev Mol Cell Biol (2013) 2.17
Nucleosome-depleted regions in cell-cycle-regulated promoters ensure reliable gene expression in every cell cycle. Dev Cell (2010) 1.97
Cell size control in yeast. Curr Biol (2012) 1.96
Response to hyperosmotic stress. Genetics (2012) 1.95
A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells. PLoS One (2008) 1.90
An overview of Cdk1-controlled targets and processes. Cell Div (2010) 1.66
A conserved G₁ regulatory circuit promotes asynchronous behavior of nuclei sharing a common cytoplasm. Cell Cycle (2010) 1.63
Regulating DNA replication in eukarya. Cold Spring Harb Perspect Biol (2013) 1.52
High functional overlap between MluI cell-cycle box binding factor and Swi4/6 cell-cycle box binding factor in the G1/S transcriptional program in Saccharomyces cerevisiae. Genetics (2005) 1.51
Daughter-specific transcription factors regulate cell size control in budding yeast. PLoS Biol (2009) 1.48
DNA replication checkpoint promotes G1-S transcription by inactivating the MBF repressor Nrm1. Proc Natl Acad Sci U S A (2008) 1.46
Ribosome biogenesis is sensed at the Start cell cycle checkpoint. Mol Biol Cell (2006) 1.43
A Stochastic Model of the Yeast Cell Cycle Reveals Roles for Feedback Regulation in Limiting Cellular Variability. PLoS Comput Biol (2016) 1.39
Distinct interactions select and maintain a specific cell fate. Mol Cell (2011) 1.38
What determines cell size? BMC Biol (2012) 1.38
Cell size checkpoint control by the retinoblastoma tumor suppressor pathway. PLoS Genet (2006) 1.36
A model of yeast cell-cycle regulation based on multisite phosphorylation. Mol Syst Biol (2010) 1.33
Commitment to a cellular transition precedes genome-wide transcriptional change. Mol Cell (2011) 1.31
Origin of irreversibility of cell cycle start in budding yeast. PLoS Biol (2010) 1.30
Green light for the cell cycle. EMBO J (2005) 1.30
Evolution of networks and sequences in eukaryotic cell cycle control. Philos Trans R Soc Lond B Biol Sci (2011) 1.30
CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression. Cell (2012) 1.29
Cyclin Cln3p links G1 progression to hyphal and pseudohyphal development in Candida albicans. Eukaryot Cell (2005) 1.22
Recruitment of Cln3 cyclin to promoters controls cell cycle entry via histone deacetylase and other targets. PLoS Biol (2009) 1.20
Activation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast. EMBO J (2007) 1.20
The DNA replication checkpoint directly regulates MBF-dependent G1/S transcription. Mol Cell Biol (2008) 1.18
Acetyl-CoA induces transcription of the key G1 cyclin CLN3 to promote entry into the cell division cycle in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2013) 1.17
DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1. EMBO J (2012) 1.17
Aneuploid yeast strains exhibit defects in cell growth and passage through START. Mol Biol Cell (2013) 1.16
Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes. EMBO J (2012) 1.16
The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation. Nat Commun (2012) 1.15
The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle. Genome Biol (2010) 1.15
The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promoters. EMBO J (2009) 1.13
F-box protein specificity for g1 cyclins is dictated by subcellular localization. PLoS Genet (2012) 1.11
Feedforward regulation ensures stability and rapid reversibility of a cellular state. Mol Cell (2013) 1.09
A systematic analysis of cell cycle regulators in yeast reveals that most factors act independently of cell size to control initiation of division. PLoS Genet (2012) 1.07
Genomewide identification of pheromone-targeted transcription in fission yeast. BMC Genomics (2006) 1.06
Signaling pathways that control cell proliferation. Cold Spring Harb Perspect Biol (2013) 1.05
FACT prevents the accumulation of free histones evicted from transcribed chromatin and a subsequent cell cycle delay in G1. PLoS Genet (2010) 1.05
A systems biology dynamical model of mammalian G1 cell cycle progression. Mol Syst Biol (2007) 1.05
Exploring the yeast acetylome using functional genomics. Cell (2012) 1.05
Cell size at S phase initiation: an emergent property of the G1/S network. PLoS Comput Biol (2007) 1.03
Topology and control of the cell-cycle-regulated transcriptional circuitry. Genetics (2014) 1.03
Start and the restriction point. Curr Opin Cell Biol (2013) 1.01
A general G1/S-phase cell-cycle control module in the flowering plant Arabidopsis thaliana. PLoS Genet (2012) 1.01
Antagonistic gene transcripts regulate adaptation to new growth environments. Proc Natl Acad Sci U S A (2011) 0.99
Dual regulation by pairs of cyclin-dependent protein kinases and histone deacetylases controls G1 transcription in budding yeast. PLoS Biol (2009) 0.98
Regulation of histone gene expression in budding yeast. Genetics (2012) 0.98
Phosphate-activated cyclin-dependent kinase stabilizes G1 cyclin to trigger cell cycle entry. Mol Cell Biol (2013) 0.97
The F-box protein Met30 is required for multiple steps in the budding yeast cell cycle. Mol Cell Biol (2005) 0.97
Whi5 regulation by site specific CDK-phosphorylation in Saccharomyces cerevisiae. PLoS One (2009) 0.97
Stb1 collaborates with other regulators to modulate the G1-specific transcriptional circuit. Mol Cell Biol (2008) 0.97
Pathocycles: Ustilago maydis as a model to study the relationships between cell cycle and virulence in pathogenic fungi. Mol Genet Genomics (2006) 0.97
Whi3, a developmental regulator of budding yeast, binds a large set of mRNAs functionally related to the endoplasmic reticulum. J Biol Chem (2008) 0.96
Npr2, yeast homolog of the human tumor suppressor NPRL2, is a target of Grr1 required for adaptation to growth on diverse nitrogen sources. Eukaryot Cell (2010) 0.96
An algorithm to automate yeast segmentation and tracking. PLoS One (2013) 0.96
A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression. Proc Natl Acad Sci U S A (2011) 0.96
Ccr4 alters cell size in yeast by modulating the timing of CLN1 and CLN2 expression. Genetics (2008) 0.96
Dilution of the cell cycle inhibitor Whi5 controls budding-yeast cell size. Nature (2015) 0.95
Bem1p, a scaffold signaling protein, mediates cyclin-dependent control of vacuolar homeostasis in Saccharomyces cerevisiae. Genes Dev (2005) 0.95
p107 in the public eye: an Rb understudy and more. Cell Div (2010) 0.94
Design principles of the yeast G1/S switch. PLoS Biol (2013) 0.92
Molecular mechanisms creating bistable switches at cell cycle transitions. Open Biol (2013) 0.92
Cell cycle-dependent regulation of Saccharomyces cerevisiae donor preference during mating-type switching by SBF (Swi4/Swi6) and Fkh1. Mol Cell Biol (2006) 0.92
Regulation of a transcription factor network by Cdk1 coordinates late cell cycle gene expression. EMBO J (2014) 0.92
Loss of the SUMO protease Ulp2 triggers a specific multichromosome aneuploidy. Genes Dev (2016) 0.91
A systematic screen for transcriptional regulators of the yeast cell cycle. Genetics (2008) 0.91
Spt10 and Swi4 control the timing of histone H2A/H2B gene activation in budding yeast. Mol Cell Biol (2010) 0.91
The linear interplay of intrinsic and extrinsic noises ensures a high accuracy of cell fate selection in budding yeast. Sci Rep (2014) 0.90
Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages. BMC Evol Biol (2014) 0.90
Systematic identification of cell size regulators in budding yeast. Mol Syst Biol (2014) 0.89
Coevolution of cyclin Pcl5 and its substrate Gcn4. Eukaryot Cell (2005) 0.89
Feedback loops and reciprocal regulation: recurring motifs in the systems biology of the cell cycle. Curr Opin Cell Biol (2013) 0.89
Identification of a conserved F-box protein 6 interactor essential for endocytosis and cytokinesis in fission yeast. Biochem J (2009) 0.89
Coordination of cell growth and division by the ubiquitin-proteasome system. Semin Cell Dev Biol (2012) 0.89
Functional connection between the Clb5 cyclin, the protein kinase C pathway and the Swi4 transcription factor in Saccharomyces cerevisiae. Genetics (2005) 0.89
Why minimal is not optimal: driving the mammalian cell cycle--and drug discovery--with a physiologic CDK control network. Cell Cycle (2012) 0.88
Repressive chromatin affects factor binding at yeast HO (homothallic switching) promoter. J Biol Chem (2011) 0.88
RB from a bud's eye view. Cell (2004) 0.88
Identification of the molecular mechanisms for cell-fate selection in budding yeast through mathematical modeling. Biophys J (2013) 0.86
A pharmaco-epistasis strategy reveals a new cell size controlling pathway in yeast. Mol Syst Biol (2013) 0.85
Repression of G1/S transcription is mediated via interaction of the GTB motifs of Nrm1 and Whi5 with Swi6. Mol Cell Biol (2013) 0.85
Method for identifying phosphorylated substrates of specific cyclin/cyclin-dependent kinase complexes. Proc Natl Acad Sci U S A (2014) 0.84
What makes the engine hum: Rad6, a cell cycle supercharger. Cell Cycle (2012) 0.84
Xbp1 directs global repression of budding yeast transcription during the transition to quiescence and is important for the longevity and reversibility of the quiescent state. PLoS Genet (2013) 0.84
G1/S transcription factor orthologues Swi4p and Swi6p are important but not essential for cell proliferation and influence hyphal development in the fungal pathogen Candida albicans. Eukaryot Cell (2011) 0.84
The Rts1 regulatory subunit of protein phosphatase 2A is required for control of G1 cyclin transcription and nutrient modulation of cell size. PLoS Genet (2009) 0.83
Simple rules for complex processes: new lessons from the budding yeast cell cycle. Mol Cell (2011) 0.83
Protein acetylation and acetyl coenzyme a metabolism in budding yeast. Eukaryot Cell (2014) 0.83
Dancing the cell cycle two-step: regulation of yeast G1-cell-cycle genes by chromatin structure. Trends Biochem Sci (2013) 0.82
Genetic determinants of cell size at birth and their impact on cell cycle progression in Saccharomyces cerevisiae. G3 (Bethesda) (2013) 0.82
Multiple pathways for suppression of mutants affecting G1-specific transcription in Saccharomyces cerevisiae. Genetics (2005) 0.82
Role of a Candida albicans Nrm1/Whi5 homologue in cell cycle gene expression and DNA replication stress response. Mol Microbiol (2012) 0.82
Cell cycle commitment in budding yeast emerges from the cooperation of multiple bistable switches. Open Biol (2011) 0.82
Cdk phosphorylation of the Ste11 transcription factor constrains differentiation-specific transcription to G1. Genes Dev (2007) 0.81
DTASelect and Contrast: tools for assembling and comparing protein identifications from shotgun proteomics. J Proteome Res (2003) 12.31
Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell (2005) 10.68
Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome. Science (2002) 7.49
Phytophthora genome sequences uncover evolutionary origins and mechanisms of pathogenesis. Science (2006) 6.74
Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol Cell (2007) 5.31
Assigning function to yeast proteins by integration of technologies. Mol Cell (2003) 4.58
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2. Nature (2007) 4.54
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature (2008) 4.43
Hepatic glucose sensing via the CREB coactivator CRTC2. Science (2008) 4.05
Shotgun identification of protein modifications from protein complexes and lens tissue. Proc Natl Acad Sci U S A (2002) 3.70
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome. Nature (2011) 3.56
Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms. Science (2004) 3.48
BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases. Mol Cell (2003) 3.43
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2. Nature (2012) 3.38
Determination and comparison of the baseline proteomes of the versatile microbe Rhodopseudomonas palustris under its major metabolic states. J Proteome Res (2006) 3.32
TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science (2006) 3.26
Automatic quality assessment of peptide tandem mass spectra. Bioinformatics (2004) 2.70
Tea4p links microtubule plus ends with the formin for3p in the establishment of cell polarity. Dev Cell (2005) 2.65
Swi1 and Swi3 are components of a replication fork protection complex in fission yeast. Mol Cell Biol (2004) 2.55
Was Rodney Ledward a statistical outlier? Retrospective analysis using routine hospital data to identify gynaecologists' performance. BMJ (2005) 2.55
Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae. Mol Biol Cell (2003) 2.48
Cytoskeletal components of an invasion machine--the apical complex of Toxoplasma gondii. PLoS Pathog (2006) 2.43
Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol Cell Biol (2002) 2.32
Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain. Nat Cell Biol (2004) 2.30
TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. J Biol Chem (2004) 2.25
Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA. Cell (2002) 2.23
Transcriptional and proteomic analysis of a ferric uptake regulator (fur) mutant of Shewanella oneidensis: possible involvement of fur in energy metabolism, transcriptional regulation, and oxidative stress. Appl Environ Microbiol (2002) 2.14
Formation and composition of the Bacillus anthracis endospore. J Bacteriol (2004) 2.12
Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site. Mol Cell (2010) 2.02
Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo. Proc Natl Acad Sci U S A (2004) 1.96
Grr1-dependent inactivation of Mth1 mediates glucose-induced dissociation of Rgt1 from HXT gene promoters. Mol Biol Cell (2003) 1.96
Effect of pioglitazone on cardiovascular outcome in diabetes and chronic kidney disease. J Am Soc Nephrol (2007) 1.92
Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Mol Cell (2006) 1.92
Cell cycle-dependent assembly of a Gin4-septin complex. Mol Biol Cell (2002) 1.83
Applicability of tandem affinity purification MudPIT to pathway proteomics in yeast. Mol Cell Proteomics (2003) 1.82
Regulation of pluripotency and self- renewal of ESCs through epigenetic-threshold modulation and mRNA pruning. Cell (2012) 1.76
Automatic validation of phosphopeptide identifications from tandem mass spectra. Anal Chem (2007) 1.70
Three distinct condensin complexes control C. elegans chromosome dynamics. Curr Biol (2009) 1.70
Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface. PLoS Pathog (2011) 1.67
Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex. Biochim Biophys Acta (2005) 1.66
The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex. Mol Cell Biol (2006) 1.65
Staphylococcus aureus fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia. Infect Immun (2010) 1.59
Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control. Mol Biol Cell (2008) 1.58
Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis. Mol Biol Cell (2004) 1.52
Replication checkpoint kinase Cds1 regulates recombinational repair protein Rad60. Mol Cell Biol (2003) 1.50
Gene and protein expression profiles of Shewanella oneidensis during anaerobic growth with different electron acceptors. OMICS (2002) 1.48
Azospirillum genomes reveal transition of bacteria from aquatic to terrestrial environments. PLoS Genet (2011) 1.45
Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1. Proc Natl Acad Sci U S A (2013) 1.45
Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry. J Biol Chem (2013) 1.43
Role of oxysterol binding protein in hepatitis C virus infection. J Virol (2009) 1.43
Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiae. Mol Biol Cell (2007) 1.41
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. Nat Struct Mol Biol (2010) 1.41
The Clp1/Cdc14 phosphatase contributes to the robustness of cytokinesis by association with anillin-related Mid1. J Cell Biol (2008) 1.38
MS2Grouper: group assessment and synthetic replacement of duplicate proteomic tandem mass spectra. J Am Soc Mass Spectrom (2005) 1.37
HOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusion. EMBO J (2010) 1.37
RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress. EMBO J (2003) 1.35
HDAC4 governs a transcriptional program essential for synaptic plasticity and memory. Cell (2012) 1.35
Regulation and recognition of SCFGrr1 targets in the glucose and amino acid signaling pathways. Mol Cell Biol (2004) 1.34
Phospho-regulation of the Cdc14/Clp1 phosphatase delays late mitotic events in S. pombe. Dev Cell (2006) 1.31
Dynamics of the peroxisomal import cycle of PpPex20p: ubiquitin-dependent localization and regulation. J Cell Biol (2006) 1.27
Phosphorylation of Rad55 on serines 2, 8, and 14 is required for efficient homologous recombination in the recovery of stalled replication forks. Mol Cell Biol (2006) 1.27
Determining the protein repertoire of Cryptosporidium parvum sporozoites. Proteomics (2008) 1.21
The role of GRASP55 in Golgi fragmentation and entry of cells into mitosis. Mol Biol Cell (2008) 1.20
Tolerability of once-weekly alendronate in patients with osteoporosis: a randomized, double-blind, placebo-controlled study. Mayo Clin Proc (2002) 1.19
DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1. EMBO J (2012) 1.17
ProRata: A quantitative proteomics program for accurate protein abundance ratio estimation with confidence interval evaluation. Anal Chem (2006) 1.16
Pioglitazone use and heart failure in patients with type 2 diabetes and preexisting cardiovascular disease: data from the PROactive study (PROactive 08). Diabetes Care (2007) 1.16
Expressed peptide tags: an additional layer of data for genome annotation. J Proteome Res (2006) 1.14
A unique covalent bond in basement membrane is a primordial innovation for tissue evolution. Proc Natl Acad Sci U S A (2013) 1.12
Regulation of myoblast differentiation by the nuclear envelope protein NET39. Mol Cell Biol (2009) 1.11
Proteomic characterization of the Chlamydomonas reinhardtii chloroplast ribosome. Identification of proteins unique to th e70 S ribosome. J Biol Chem (2003) 1.09
Protein disulfide isomerase serves as a molecular chaperone to maintain estrogen receptor alpha structure and function. Mol Endocrinol (2006) 1.08
Robust estimation of peptide abundance ratios and rigorous scoring of their variability and bias in quantitative shotgun proteomics. Anal Chem (2006) 1.08
Large-scale differential proteome analysis in Plasmodium falciparum under drug treatment. PLoS One (2008) 1.07
Shotgun proteomics: identification of unique protein profiles of apoptotic bodies from biliary epithelial cells. Hepatology (2014) 1.06
Topology and control of the cell-cycle-regulated transcriptional circuitry. Genetics (2014) 1.03
The host-range, genomics and proteomics of Escherichia coli O157:H7 bacteriophage rV5. Virol J (2013) 1.02
The evolutionary imprint of domestication on genome variation and function of the filamentous fungus Aspergillus oryzae. Curr Biol (2012) 1.02
The malarial parasite Plasmodium falciparum imports the human protein peroxiredoxin 2 for peroxide detoxification. Proc Natl Acad Sci U S A (2009) 1.02
Saccharomyces cerevisiae Ime2 phosphorylates Sic1 at multiple PXS/T sites but is insufficient to trigger Sic1 degradation. Biochem J (2006) 1.00
The SBF- and MBF-associated protein Msa1 is required for proper timing of G1-specific transcription in Saccharomyces cerevisiae. J Biol Chem (2007) 1.00
Metalloendoprotease cleavage triggers gelsolin amyloidogenesis. EMBO J (2005) 1.00
Obesity and altered glucose metabolism impact HDL composition in CETP transgenic mice: a role for ovarian hormones. J Lipid Res (2012) 0.99
Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidative stress. Mol Biol Cell (2006) 0.98
The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase. Mol Biol Cell (2010) 0.98
Long isoform mouse selenoprotein P (Sepp1) supplies rat myoblast L8 cells with selenium via endocytosis mediated by heparin binding properties and apolipoprotein E receptor-2 (ApoER2). J Biol Chem (2012) 0.97
Dual-tagging system for the affinity purification of mammalian protein complexes. Biotechniques (2007) 0.97
Stb1 collaborates with other regulators to modulate the G1-specific transcriptional circuit. Mol Cell Biol (2008) 0.97
Whi5 regulation by site specific CDK-phosphorylation in Saccharomyces cerevisiae. PLoS One (2009) 0.97
Quantitative mass spectrometry identifies drug targets in cancer stem cell-containing side population. Stem Cells (2008) 0.96