Identification of DNA 3'-phosphatase active site residues and their differential role in DNA binding, Mg2+ coordination, and catalysis.

PubWeight™: 0.99‹?› | Rank: Top 15%

🔗 View Article (PMID 15222769)

Published in Biochemistry on July 06, 2004

Authors

Rajashree A Deshpande1, Thomas E Wilson

Author Affiliations

1: Department of Pathology, University of Michigan Medical School, 1301 Catherine Road, M4214 Medical Sciences Building I, Box 0602, Ann Arbor, Michigan 48109-0602, USA.

Articles by these authors

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells. Nat Immunol (2003) 4.81

Nonhomologous end joining in yeast. Annu Rev Genet (2005) 3.32

Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage. Proc Natl Acad Sci U S A (2002) 2.50

Mycobacterial Ku and ligase proteins constitute a two-component NHEJ repair machine. Science (2004) 2.04

Compound heterozygosity for loss-of-function lysyl-tRNA synthetase mutations in a patient with peripheral neuropathy. Am J Hum Genet (2010) 1.96

Accessibility of home blood pressure monitors for blind and visually impaired people. J Diabetes Sci Technol (2007) 1.91

Enhancement of Saccharomyces cerevisiae end-joining efficiency by cell growth stage but not by impairment of recombination. Genetics (2002) 1.85

Repair of double-strand breaks by end joining. Cold Spring Harb Perspect Biol (2013) 1.58

DNA joint dependence of pol X family polymerase action in nonhomologous end joining. J Biol Chem (2005) 1.55

Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae. Genetics (2008) 1.55

Rejoining of DNA double-strand breaks as a function of overhang length. Mol Cell Biol (2005) 1.52

Evolutionary and functional conservation of the DNA non-homologous end-joining protein, XLF/Cernunnos. J Biol Chem (2006) 1.50

Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4. DNA Repair (Amst) (2007) 1.29

Replication stress and mechanisms of CNV formation. Curr Opin Genet Dev (2012) 1.23

Discovery of mutations in Saccharomyces cerevisiae by pooled linkage analysis and whole-genome sequencing. Genetics (2010) 1.23

SnapShot: Nonhomologous DNA end joining (NHEJ). Cell (2010) 1.21

Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response. Proc Natl Acad Sci U S A (2013) 1.19

Mutations of the Yku80 C terminus and Xrs2 FHA domain specifically block yeast nonhomologous end joining. Mol Cell Biol (2005) 1.18

Hydroxyurea induces de novo copy number variants in human cells. Proc Natl Acad Sci U S A (2011) 1.17

A recurrent loss-of-function alanyl-tRNA synthetase (AARS) mutation in patients with Charcot-Marie-Tooth disease type 2N (CMT2N). Hum Mutat (2011) 1.14

Recruitment of Saccharomyces cerevisiae Dnl4-Lif1 complex to a double-strand break requires interactions with Yku80 and the Xrs2 FHA domain. Genetics (2008) 1.12

De novo CNV formation in mouse embryonic stem cells occurs in the absence of Xrcc4-dependent nonhomologous end joining. PLoS Genet (2012) 1.07

Mycobacteriophage exploit NHEJ to facilitate genome circularization. Mol Cell (2006) 1.07

Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination. Mol Cell Biol (2010) 1.03

Genome-wide transcriptional effects of the anti-cancer agent camptothecin. PLoS One (2013) 1.00

Recurrent reciprocal RNA chimera involving YPEL5 and PPP1CB in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (2013) 0.99

Increased recombination between active tRNA genes. DNA Cell Biol (2006) 0.98

The role of yeast DNA 3'-phosphatase Tpp1 and rad1/Rad10 endonuclease in processing spontaneous and induced base lesions. J Biol Chem (2003) 0.97

New insights into NHEJ repair processes in prokaryotes. Cell Cycle (2005) 0.96

Evidence that base stacking potential in annealed 3' overhangs determines polymerase utilization in yeast nonhomologous end joining. DNA Repair (Amst) (2007) 0.95

Comparison of constitutional and replication stress-induced genome structural variation by SNP array and mate-pair sequencing. Genetics (2011) 0.95

Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair. DNA Repair (Amst) (2010) 0.90

Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity. PLoS Genet (2013) 0.84

Harnessing genomics to identify environmental determinants of heritable disease. Mutat Res (2012) 0.81

Copy number variants are produced in response to low-dose ionizing radiation in cultured cells. Environ Mol Mutagen (2013) 0.81

Abrogation of the Chk1-Pds1 checkpoint leads to tolerance of persistent single-strand breaks in Saccharomyces cerevisiae. Genetics (2005) 0.78

Restricting the ligation step of non-homologous end-joining. DNA Repair (Amst) (2007) 0.76

Yeast DNA ligase IV mutations reveal a nonhomologous end joining function of BRCT1 distinct from XRCC4/Lif1 binding. DNA Repair (Amst) (2014) 0.76

Breaking news on fragile sites in cancer. Cancer Cell (2013) 0.75

Influence of source characteristics, chemicals, and flocculation on chemically enhanced primary treatment. Water Environ Res (2008) 0.75