Published in J Immunol on July 15, 2004
Adoptive immunotherapy for cancer: building on success. Nat Rev Immunol (2006) 7.76
CD8+ T-cell memory in tumor immunology and immunotherapy. Immunol Rev (2006) 4.49
Transcriptional control of effector and memory CD8+ T cell differentiation. Nat Rev Immunol (2012) 4.44
Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. Immunity (2009) 4.42
A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection. Immunity (2009) 3.66
Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1. Immunity (2010) 3.49
Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation. Nat Immunol (2010) 3.48
STAT5 is a potent negative regulator of TFH cell differentiation. J Exp Med (2012) 3.37
An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells. Immunity (2011) 2.77
A critical role for STAT3 transcription factor signaling in the development and maintenance of human T cell memory. Immunity (2011) 2.15
Metabolic switching and fuel choice during T-cell differentiation and memory development. Immunol Rev (2012) 2.03
Generation of effector CD8+ T cells and their conversion to memory T cells. Immunol Rev (2010) 1.85
Pathogen-induced inflammatory environment controls effector and memory CD8+ T cell differentiation. J Immunol (2011) 1.66
BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes. Proc Natl Acad Sci U S A (2005) 1.61
The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis. J Exp Med (2010) 1.59
Programming CD8+ T cells for effective immunotherapy. Curr Opin Immunol (2006) 1.51
Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells. Nat Immunol (2011) 1.51
Early signals during CD8 T cell priming regulate the generation of central memory cells. J Immunol (2010) 1.49
Memory CD8+ T cell differentiation. Ann N Y Acad Sci (2010) 1.47
Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection. J Immunol (2010) 1.42
Diversity in CD8(+) T cell differentiation. Curr Opin Immunol (2009) 1.32
Surviving the crash: transitioning from effector to memory CD8+ T cell. Semin Immunol (2009) 1.31
Memories that last forever: strategies for optimizing vaccine T-cell memory. Blood (2009) 1.23
Early events governing memory CD8+ T-cell differentiation. Int Immunol (2010) 1.22
A genome-wide regulatory network identifies key transcription factors for memory CD8⁺ T-cell development. Nat Commun (2013) 1.13
The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection. J Exp Med (2015) 1.09
The CD8 T-cell road to immunotherapy of toxoplasmosis. Immunotherapy (2011) 1.08
The BTB-ZF family of transcription factors: key regulators of lineage commitment and effector function development in the immune system. J Immunol (2011) 1.04
Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy. Immunol Rev (2014) 1.03
Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function. J Allergy Clin Immunol (2013) 1.01
IL-12 selectively programs effector pathways that are stably expressed in human CD8+ effector memory T cells in vivo. Blood (2011) 1.00
Epitope density influences CD8+ memory T cell differentiation. PLoS One (2010) 0.98
Retracted POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation. J Biol Chem (2012) 0.95
Aberrant regulation of hematopoiesis by T cells in BAZF-deficient mice. Mol Cell Biol (2007) 0.93
The BTB-ZF transcription factors. Cell Cycle (2012) 0.93
Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cells. Hum Immunol (2010) 0.92
Transcriptional regulation of effector and memory CD8+ T cell fates. Curr Opin Immunol (2013) 0.91
Nature and nurture: T-cell receptor-dependent and T-cell receptor-independent differentiation cues in the selection of the memory T-cell pool. Immunology (2010) 0.89
T cell responses: naive to memory and everything in between. Adv Physiol Educ (2013) 0.89
Manipulating the tumor microenvironment ex vivo for enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy. Clin Cancer Res (2014) 0.87
Shaping successful and unsuccessful CD8 T cell responses following infection. J Biomed Biotechnol (2010) 0.87
A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet. Nat Immunol (2016) 0.85
Asymptomatic memory CD8+ T cells: from development and regulation to consideration for human vaccines and immunotherapeutics. Hum Vaccin Immunother (2014) 0.85
CD40-activated B cells can efficiently prime antigen-specific naïve CD8+ T cells to generate effector but not memory T cells. PLoS One (2012) 0.84
Blimp-1 connects the intrinsic and extrinsic regulation of T cell homeostasis. J Clin Immunol (2007) 0.80
IL-6 production by dendritic cells is dispensable for CD8+ memory T-cell generation. Biomed Res Int (2012) 0.80
Gammaherpesvirus latency differentially impacts the generation of primary versus secondary memory CD8+ T cells during subsequent infection. J Virol (2014) 0.79
Zbtb1 Safeguards Genome Integrity and Prevents p53-Mediated Apoptosis in Proliferating Lymphoid Progenitors. J Immunol (2016) 0.78
Role of the Transcriptional Repressor BCL6 in Allergic Response and Inflammation. World Allergy Organ J (2008) 0.77
Disparate roles for STAT5 in primary and secondary CTL responses. J Immunol (2013) 0.77
Development of chronic allergic responses by dampening Bcl6-mediated suppressor activity in memory T helper 2 cells. Proc Natl Acad Sci U S A (2017) 0.75
IL2Rβ-dependent signals drive terminal exhaustion and suppress memory development during chronic viral infection. Proc Natl Acad Sci U S A (2016) 0.75
Differential Requirements for Tcf1 Long Isoforms in CD8(+) and CD4(+) T Cell Responses to Acute Viral Infection. J Immunol (2017) 0.75
The role of autophagy during the early neonatal starvation period. Nature (2004) 22.40
Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med (2002) 4.25
A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations. Am J Transplant (2005) 2.74
IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice. Am J Respir Crit Care Med (2008) 2.62
CD25+CD4+ T cells contribute to the control of memory CD8+ T cells. Proc Natl Acad Sci U S A (2002) 2.44
Activation of STAT3 by the hepatitis C virus core protein leads to cellular transformation. J Exp Med (2002) 2.23
Role for Bcl-6 in the generation and maintenance of memory CD8+ T cells. Nat Immunol (2002) 2.20
IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice. J Allergy Clin Immunol (2006) 2.16
Rescue purification maximizes the use of human islet preparations for transplantation. Am J Transplant (2005) 2.04
Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells. Immunity (2002) 1.94
Increased levels of soluble triggering receptor expressed on myeloid cells-1 in patients with acute pancreatitis. Crit Care Med (2008) 1.84
Extremely high interleukin-6 blood levels and outcome in the critically ill are associated with tumor necrosis factor- and interleukin-1-related gene polymorphisms. Crit Care Med (2005) 1.79
Core protein of hepatitis C virus induces cardiomyopathy. Circ Res (2004) 1.73
DNA polymerase theta is preferentially expressed in lymphoid tissues and upregulated in human cancers. Int J Cancer (2004) 1.72
Possibility of islet transplantation from a nonheartbeating donor pancreas resuscitated by the two-layer method. Transplantation (2005) 1.65
The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis. J Exp Med (2010) 1.59
Significant increase of serum high-mobility group box chromosomal protein 1 levels in patients with severe acute pancreatitis. Pancreas (2006) 1.58
DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes. Proc Natl Acad Sci U S A (2005) 1.53
Serum interleukin-15 level is a useful predictor of the complications and mortality in severe acute pancreatitis. Surgery (2007) 1.47
Transcriptional activation of survivin through the NF-kappaB pathway by human T-cell leukemia virus type I tax. Int J Cancer (2005) 1.46
Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation. J Clin Invest (2005) 1.46
Blockade of high mobility group box-1 protein attenuates experimental severe acute pancreatitis. World J Gastroenterol (2006) 1.44
A role for c-fos/activator protein 1 in B lymphocyte terminal differentiation. J Immunol (2005) 1.37
Two waves of memory B-cell generation in the primary immune response. Int Immunol (2005) 1.36
Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model. J Clin Invest (2007) 1.32
Critical role of the IgM Fc receptor in IgM homeostasis, B-cell survival, and humoral immune responses. Proc Natl Acad Sci U S A (2012) 1.29
Mesenchymal stem cells suppress B-cell terminal differentiation. Exp Hematol (2009) 1.25
Inhibition of p38 pathway suppresses human islet production of pro-inflammatory cytokines and improves islet graft function. Am J Transplant (2005) 1.24
Bcl6 controls granzyme B expression in effector CD8+ T cells. Eur J Immunol (2006) 1.24
Crystal structure of the L intermediate of bacteriorhodopsin: evidence for vertical translocation of a water molecule during the proton pumping cycle. J Mol Biol (2004) 1.23
A lysosomal protein negatively regulates surface T cell antigen receptor expression by promoting CD3zeta-chain degradation. Immunity (2008) 1.20
Selection of pancreaticojejunostomy techniques according to pancreatic texture and duct size. Arch Surg (2002) 1.18
Targeted disruption of TGF-beta-Smad3 signaling leads to enhanced neointimal hyperplasia with diminished matrix deposition in response to vascular injury. Circ Res (2005) 1.18
Breakdown of intestinal mucosa via accelerated apoptosis increases intestinal permeability in experimental severe acute pancreatitis. J Surg Res (2006) 1.16
Bcl6 is essential for the generation of long-term memory CD4+ T cells. Int Immunol (2007) 1.16
Carcinosarcoma of the gallbladder with chondroid differentiation. J Gastroenterol (2002) 1.15
JunD/AP-1 and STAT3 are the major enhancer molecules for high Bcl6 expression in germinal center B cells. Int Immunol (2006) 1.15
Prostaglandin D2 reinforces Th2 type inflammatory responses of airways to low-dose antigen through bronchial expression of macrophage-derived chemokine. J Exp Med (2003) 1.12
Significant elevation of serum interleukin-18 levels in patients with acute pancreatitis. J Gastroenterol (2006) 1.12
Enhancement of anti-tumor immunity by high levels of Th1 and Th17 with a combination of dendritic cell fusion hybrids and regulatory T cell depletion in pancreatic cancer. Oncol Rep (2009) 1.11
Expression of receptor for advanced glycation end products (RAGE) and MMP-9 in human pancreatic cancer cells. Hepatogastroenterology (2004) 1.10
Increase of high-mobility group box chromosomal protein 1 in blood and injured organs in experimental severe acute pancreatitis. Pancreas (2007) 1.10
Bcl6 is a transcriptional repressor for the IL-18 gene. J Immunol (2003) 1.08
A novel technique of finger-assisted laparoscopic surgery. Am J Surg (2004) 1.07
Adenocarcinoma arising in gastric inverted hyperplastic polyp: a case report and review of the literature. Pathol Res Pract (2006) 1.07
Resection of gallbladder cancer with hepatic metastasis after chemotherapy with gemcitabine. J Hepatobiliary Pancreat Surg (2008) 1.04
Role of DNA polymerase theta in tolerance of endogenous and exogenous DNA damage in mouse B cells. Genes Cells (2006) 1.04
Reductive surgery plus percutaneous isolated hepatic perfusion for multiple advanced hepatocellular carcinoma. Ann Surg (2004) 1.03
Silymarin protects pancreatic beta-cells against cytokine-mediated toxicity: implication of c-Jun NH2-terminal kinase and janus kinase/signal transducer and activator of transcription pathways. Endocrinology (2004) 1.01
Association of VEGF genotype with mRNA level in colorectal adenocarcinomas. Biochem Biophys Res Commun (2004) 1.01
Kinetics and protective role of autophagy in a mouse cecal ligation and puncture-induced sepsis. Crit Care (2013) 1.00
Significance of Akt phosphorylation on tumor growth and vascular endothelial growth factor expression in human gastric carcinoma. Pathobiology (2006) 1.00
Influence of toll-like receptor 4, CD14, tumor necrosis factor, and interleukine-10 gene polymorphisms on clinical outcome in Japanese critically ill patients. J Surg Res (2005) 1.00
Histopathological predictors of regional lymph node metastasis at the invasive front in early colorectal cancer. Histopathology (2011) 0.99
Perfluorocarbon for organ preservation before transplantation. Transplantation (2002) 0.99
Identification of Nd1, a novel murine kelch family protein, involved in stabilization of actin filaments. J Biol Chem (2002) 0.99
Efficacy of the oxygen-charged static two-layer method for short-term pancreas preservation and islet isolation from nonhuman primate and human pancreata. Cell Transplant (2002) 0.99
The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution. J Biol Chem (2003) 0.98
Bcl6 is required for the development of mouse CD4+ and CD8α+ dendritic cells. J Immunol (2010) 0.98
Impaired lymphocyte development and function in Clast5/Stra13/DEC1-transgenic mice. Eur J Immunol (2004) 0.98
BAZF, a novel component of cullin3-based E3 ligase complex, mediates VEGFR and Notch cross-signaling in angiogenesis. Blood (2012) 0.97
Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas. Drug Metab Dispos (2002) 0.97
Enrichment of putative pancreatic progenitor cells from mice by sorting for prominin1 (CD133) and platelet-derived growth factor receptor beta. Stem Cells (2008) 0.97
Up-regulation of interleukin-10 mRNA expression in peripheral leukocytes predicts poor outcome and diminished human leukocyte antigen-DR expression on monocytes in septic patients. J Surg Res (2007) 0.97
Pancreatic diabetes in a follow-up survey of chronic pancreatitis in Japan. J Gastroenterol (2007) 0.96
Suppression of human pancreatic carcinoma cell growth and invasion by epigallocatechin-3-gallate. Pancreas (2002) 0.95
Double cancer of gall bladder and bile duct not associated with anomalous junction of the pancreaticobiliary duct system. Jpn J Clin Oncol (2006) 0.95
A large stone detected in Roux-en-Y jejunal limb 20 years after excision of congenital choledochal cyst. Surgery (2006) 0.95
Gastric and intestinal claudin expression at the invasive front of gastric carcinoma. Cancer Sci (2007) 0.94
Augmented antibody response with premature germinal center regression in CD40L transgenic mice. J Immunol (2010) 0.94
Superior anti-tumor protection and therapeutic efficacy of vaccination with allogeneic and semiallogeneic dendritic cell/tumor cell fusion hybrids for murine colon adenocarcinoma. Cancer Immunol Immunother (2006) 0.94
Laparoscopy-assisted colon resection for mucosa-associated lymphoid tissue (MALT) lymphoma in the cecum. Hepatogastroenterology (2003) 0.92
Clast5/Stra13 is a negative regulator of B lymphocyte activation. Biochem Biophys Res Commun (2002) 0.92
A MEK inhibitor (U0126) prolongs survival in nude mice bearing human gallbladder cancer cells with K-ras mutation: analysis in a novel orthotopic inoculation model. Int J Oncol (2003) 0.91
Ncx (Enx, Hox11L.1) is required for neuronal cell death in enteric ganglia of mice. J Pediatr Surg (2007) 0.91
Risk factors influencing pancreatic leakage and the mortality after pancreaticoduodenectomy in a medium-volume hospital. Hepatogastroenterology (2002) 0.90
Cronkhite-Canada syndrome presenting as recurrent severe acute pancreatitis. Gastrointest Endosc (2008) 0.90
Influence of pancreas preservation on human islet isolation outcomes: impact of the two-layer method. Transplantation (2004) 0.90
Family history of cancer in Japanese gastric cancer patients. Gastric Cancer (2007) 0.89
Role of Clast1 in development of cerebellar granule cells. Brain Res (2006) 0.89
Simple scoring system for the prediction of the prognosis of severe acute pancreatitis. Surgery (2006) 0.89
Pancreaticobronchial fistula associated with chronic pancreatitis: report of a case. Surg Today (2007) 0.88