Genes and the parsing of cognitive processes.

Individual differences in executive functions are almost entirely genetic in origin. J Exp Psychol Gen (2008) 3.76

The Consortium on the Genetics of Schizophrenia: neurocognitive endophenotypes. Schizophr Bull (2006) 2.53

Genetic variation in components of dopamine neurotransmission impacts ventral striatal reactivity associated with impulsivity. Mol Psychiatry (2007) 2.29

Bridging animal and human models of exercise-induced brain plasticity. Trends Cogn Sci (2013) 1.79

A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States. Am J Hum Genet (2004) 1.76

Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease: ICICLE-PD study. Brain (2014) 1.70

Genetics of cognition in epilepsy. Epilepsy Behav (2014) 1.51

Genes, cognition and brain through a COMT lens. Neuroscience (2009) 1.43

Human aging magnifies genetic effects on executive functioning and working memory. Front Hum Neurosci (2008) 1.41

Age-related decline in brain resources modulates genetic effects on cognitive functioning. Front Neurosci (2008) 1.33

Serotonin differentially regulates short- and long-term prediction of rewards in the ventral and dorsal striatum. PLoS One (2007) 1.30

Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia. Schizophr Res (2008) 1.29

How much of reinforcement learning is working memory, not reinforcement learning? A behavioral, computational, and neurogenetic analysis. Eur J Neurosci (2012) 1.23

Predicting impending death: inconsistency in speed is a selective and early marker. Psychol Aging (2008) 1.21

Cannabis and cognitive dysfunction: parallels with endophenotypes of schizophrenia? J Psychiatry Neurosci (2007) 1.18

COMT val158met genotype affects recruitment of neural mechanisms supporting fluid intelligence. Cereb Cortex (2008) 1.16

Dopaminergic suppression of brain deactivation responses during sequence learning. J Neurosci (2008) 1.15

Brain classification reveals the right cerebellum as the best biomarker of dyslexia. BMC Neurosci (2009) 1.11

Differential effects of COMT on gait and executive control in aging. Neurobiol Aging (2008) 1.10

KIBRA: A New Gateway to Learning and Memory? Front Aging Neurosci (2010) 1.09

Shared executive dysfunctions in unaffected relatives of patients with autism and obsessive-compulsive disorder. Eur Psychiatry (2006) 1.04

Effect of cigarette smoking on prefrontal cortical function in nondeprived smokers performing the Stroop Task. Neuropsychopharmacology (2006) 1.02

Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: a review of human brain oscillations as effective endophenotypes. Brain Res (2008) 1.01

Functional brain networks underlying perceptual switching: auditory streaming and verbal transformations. Philos Trans R Soc Lond B Biol Sci (2012) 1.01

A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia. Neuroimage (2009) 1.00

Intermediate phenotypes in schizophrenia: a selective review. Dialogues Clin Neurosci (2005) 0.99

Working memory deficits, increased anxiety-like traits, and seizure susceptibility in BDNF overexpressing mice. Learn Mem (2011) 0.98

Selective updating of working memory content modulates meso-cortico-striatal activity. Neuroimage (2011) 0.97

Category fluency, latent semantic analysis and schizophrenia: a candidate gene approach. Cortex (2013) 0.96

Ethnic differences in brain-derived neurotrophic factor Val66Met polymorphism in Croatian and Korean healthy participants. Croat Med J (2009) 0.96

Individual differences in cognition, affect, and performance: behavioral, neuroimaging, and molecular genetic approaches. Neuroimage (2011) 0.94

Synergistic effects of genetic variation in nicotinic and muscarinic receptors on visual attention but not working memory. Proc Natl Acad Sci U S A (2009) 0.94

Proton magnetic resonance spectroscopy in alcohol use disorders: a potential new endophenotype? Alcohol Clin Exp Res (2008) 0.93

Intra-individual variability in Alzheimer's disease and cognitive aging: definitions, context, and effect sizes. PLoS One (2011) 0.93

Foundations of neuroeconomics: from philosophy to practice. PLoS Biol (2008) 0.93

Using an adoption design to separate genetic, prenatal, and temperament influences on toddler executive function. Dev Psychol (2012) 0.92

Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities. PLoS One (2009) 0.92

Inter- and intra-individual covariations of hemodynamic and oscillatory gamma responses in the human cortex. Front Hum Neurosci (2009) 0.90

Neural response to working memory load varies by dopamine transporter genotype in children. Neuroimage (2010) 0.90

Placing neuroanatomical models of executive function in a developmental context: imaging and imaging--genetic strategies. Ann N Y Acad Sci (2008) 0.88

Dopaminergic polymorphisms associated with time-on-task declines and fatigue in the Psychomotor Vigilance Test. PLoS One (2012) 0.87

Imaging genomics and response to treatment with antipsychotics in schizophrenia. NeuroRx (2006) 0.87

Functional brain basis of hypnotizability. Arch Gen Psychiatry (2012) 0.87

Both a nicotinic single nucleotide polymorphism (SNP) and a noradrenergic SNP modulate working memory performance when attention is manipulated. J Cogn Neurosci (2009) 0.87

COMT and ALDH2 polymorphisms moderate associations of implicit drinking motives with alcohol use. Addict Biol (2011) 0.87

Catechol-O-methyltransferase (COMT) gene variants: possible association of the Val158Met variant with opiate addiction in Hispanic women. Am J Med Genet B Neuropsychiatr Genet (2008) 0.86

Culture and neuroscience: additive or synergistic? Soc Cogn Affect Neurosci (2010) 0.85

A combined effect of two Alzheimer's risk genes on medial temporal activity during executive attention in young adults. Neuropsychologia (2014) 0.85

Distinguishing neurocognitive functions in schizophrenia using partially ordered classification models. Schizophr Bull (2006) 0.85

Synergistic associations of catechol-O-methyltransferase and brain-derived neurotrophic factor with executive function in aging are selective and modified by apolipoprotein E. Neurobiol Aging (2014) 0.84

Neural correlates of inhibitory control and functional genetic variation in the dopamine D4 receptor gene. Neuropsychologia (2014) 0.81

5-HTTLPR polymorphism impacts task-evoked and resting-state activities of the amygdala in Han Chinese. PLoS One (2012) 0.81

Gonadectomy and hormone replacement exert region- and enzyme isoform-specific effects on monoamine oxidase and catechol-O-methyltransferase activity in prefrontal cortex and neostriatum of adult male rats. Neuroscience (2009) 0.81

Age-Related Olfactory Decline is Associated with the BDNF Val66met Polymorphism: Evidence from a Population-Based Study. Front Aging Neurosci (2010) 0.81

Estimating the inbreeding depression on cognitive behavior: a population based study of child cohort. PLoS One (2014) 0.80

Proposed mechanisms for cancer- and treatment-related cognitive changes. Semin Oncol Nurs (2013) 0.80

Potential moderators of physical activity on brain health. J Aging Res (2012) 0.80

Investigating the molecular basis of major depressive disorder etiology: a functional convergent genetic approach. Ann N Y Acad Sci (2008) 0.80

Genetic Thinking in the Study of Social Relationships: Five Points of Entry. Perspect Psychol Sci (2010) 0.80

MicroRNA-572 improves early post-operative cognitive dysfunction by down-regulating neural cell adhesion molecule 1. PLoS One (2015) 0.80

Effectiveness, relapse prevention and mechanisms of change of cognitive therapy vs. interpersonal therapy for depression: Study protocol for a randomised controlled trial. Trials (2011) 0.79

Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models. Front Psychiatry (2015) 0.79

Effects of tolcapone on working memory and brain activity in abstinent smokers: a proof-of-concept study. Drug Alcohol Depend (2013) 0.79

Neurogenetic effects on cognition in aging brains: a window of opportunity for intervention? Front Aging Neurosci (2010) 0.78

Dopamine beta hydroxylase genotype identifies individuals less susceptible to bias in computer-assisted decision making. PLoS One (2012) 0.78

COMT, BDNF, and DTNBP1 polymorphisms and cognitive functions in patients with brain tumors. Neuro Oncol (2016) 0.78

The modulatory influence of the functional COMT Val158Met polymorphism on lexical decisions and semantic priming. Front Hum Neurosci (2009) 0.78

Catechol-O-methyltransferase Val158Met polymorphism modulates gray matter volume and functional connectivity of the default mode network. PLoS One (2013) 0.78

Association of abstinence-induced alterations in working memory function and COMT genotype in smokers. Psychopharmacology (Berl) (2013) 0.77

Association between Neurocognitive Impairment and the Short Allele of the 5-HTT Promoter Polymorphism in Depression: A Pilot Study. Psychiatry J (2012) 0.77

No observable relationship between the 12 genes of nervous system and reasoning skill in a young Chinese Han population. Cell Mol Neurobiol (2011) 0.77

COMT Val158Met Polymorphism Modulates Cognitive Effects of Dietary Intervention. Front Aging Neurosci (2010) 0.77

The brain-derived neurotrophic factor (BDNF) val66met polymorphism differentially affects performance on subscales of the Wechsler Memory Scale - Third Edition (WMS-III). Front Psychol (2015) 0.76

Effects of COMT genotype on sensory gating and its modulation by nicotine: Differences in low and high P50 suppressors. Neuroscience (2013) 0.76

Genes and cognitive aging. Front Neurosci (2009) 0.76

The roles of COMT val158met status and aviation expertise in flight simulator performance and cognitive ability. Behav Genet (2010) 0.76

Animal Models of Psychosis: Current State and Future Directions. Curr Behav Neurosci Rep (2014) 0.76

An examination of the language construct in NIMH's research domain criteria: Time for reconceptualization! Am J Med Genet B Neuropsychiatr Genet (2016) 0.76

The DYX2 locus and neurochemical signaling genes contribute to speech sound disorder and related neurocognitive domains. Genes Brain Behav (2015) 0.75

Exposure to Mixtures of Metals and Neurodevelopmental Outcomes: A Multidisciplinary Review Using an Adverse Outcome Pathway Framework. Risk Anal (2015) 0.75

Novelty Seeking, Harm Avoidance, and Cerebral Responses to Conflict Anticipation: An Exploratory Study. Front Hum Neurosci (2016) 0.75

Serotonin-Related Gene Polymorphisms and Asymptomatic Neurocognitive Impairment in HIV-Infected Alcohol Abusers. Genet Res Int (2016) 0.75

Reduction of Continuous Theta Burst Stimulation-Induced Motor Plasticity in Healthy Elderly With COMT Val158Met Polymorphism. Ann Rehabil Med (2014) 0.75

People are different: tyrosine's modulating effect on cognitive control in healthy humans may depend on individual differences related to dopamine function. Front Psychol (2014) 0.75

Cognitive interventions in Alzheimer's and Parkinson's diseases: emerging mechanisms and role of imaging. Curr Opin Neurol (2016) 0.75

Catechol-O-Methyltransferase Genotype and Gait Speed Changes over 10 Years in Older Adults. J Am Geriatr Soc (2017) 0.75

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell (2003) 12.50

5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nat Neurosci (2005) 10.13

Serotonin transporter genetic variation and the response of the human amygdala. Science (2002) 9.31

Spatio-temporal transcriptome of the human brain. Nature (2011) 9.19

The MATRICS Consensus Cognitive Battery, part 1: test selection, reliability, and validity. Am J Psychiatry (2008) 9.00

Remission in schizophrenia: proposed criteria and rationale for consensus. Am J Psychiatry (2005) 6.27

Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. Am J Hum Genet (2004) 5.70

Intermediate phenotypes and genetic mechanisms of psychiatric disorders. Nat Rev Neurosci (2006) 5.70

Hierarchical organization of human cortical networks in health and schizophrenia. J Neurosci (2008) 5.19

Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance. J Neurosci (2003) 5.11

Temporal dynamics and genetic control of transcription in the human prefrontal cortex. Nature (2011) 5.01

The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology. J Neurosci (2004) 4.84

Approaching a consensus cognitive battery for clinical trials in schizophrenia: the NIMH-MATRICS conference to select cognitive domains and test criteria. Biol Psychiatry (2004) 4.46

A susceptibility gene for affective disorders and the response of the human amygdala. Arch Gen Psychiatry (2005) 4.33

Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. Proc Natl Acad Sci U S A (2003) 4.21

The amygdala response to emotional stimuli: a comparison of faces and scenes. Neuroimage (2002) 3.70

Neural mechanisms of genetic risk for impulsivity and violence in humans. Proc Natl Acad Sci U S A (2006) 3.58

Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or down. Am J Psychiatry (2003) 3.52

Neocortical modulation of the amygdala response to fearful stimuli. Biol Psychiatry (2003) 3.43

Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women. PLoS Genet (2008) 3.33

Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond. Biol Psychiatry (2006) 3.24

DNA methylation signatures in development and aging of the human prefrontal cortex. Am J Hum Genet (2012) 3.17

Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. Proc Natl Acad Sci U S A (2002) 3.11

The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort. Brain (2009) 3.03

Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia. Arch Gen Psychiatry (2003) 2.82

Regionally specific disturbance of dorsolateral prefrontal-hippocampal functional connectivity in schizophrenia. Arch Gen Psychiatry (2005) 2.78

Morphometric analysis of lateral ventricles in schizophrenia and healthy controls regarding genetic and disease-specific factors. Proc Natl Acad Sci U S A (2005) 2.73

Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease. Proc Natl Acad Sci U S A (2006) 2.71

Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proc Natl Acad Sci U S A (2005) 2.68

A validated network of effective amygdala connectivity. Neuroimage (2007) 2.58

Genes, dopamine and cortical signal-to-noise ratio in schizophrenia. Trends Neurosci (2004) 2.50

Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia. Am J Psychiatry (2003) 2.47

Imaging genomics. Br Med Bull (2003) 2.39

Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype. Nat Neurosci (2005) 2.39

Effect of catechol-O-methyltransferase val158met genotype on attentional control. J Neurosci (2005) 2.37

Efficient physical embedding of topologically complex information processing networks in brains and computer circuits. PLoS Comput Biol (2010) 2.37

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia. Nat Med (2009) 2.37

Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. Proc Natl Acad Sci U S A (2004) 2.36

Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia. Nat Neurosci (2002) 2.32

Imaging genetics: perspectives from studies of genetically driven variation in serotonin function and corticolimbic affective processing. Biol Psychiatry (2006) 2.29

Genetic variation in CACNA1C affects brain circuitries related to mental illness. Arch Gen Psychiatry (2010) 2.28

Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia. Hum Mol Genet (2006) 2.21

A common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function. Proc Natl Acad Sci U S A (2010) 2.16

Prenatal expression patterns of genes associated with neuropsychiatric disorders. Am J Psychiatry (2014) 2.14

Variation in dopamine genes influences responsivity of the human reward system. Proc Natl Acad Sci U S A (2008) 2.13

Age-related alterations in default mode network: impact on working memory performance. Neurobiol Aging (2008) 2.11

Genetic dissection of the role of catechol-O-methyltransferase in cognition and stress reactivity in mice. J Neurosci (2008) 2.08

Cognitive fitness of cost-efficient brain functional networks. Proc Natl Acad Sci U S A (2009) 2.07

Neurophysiological correlates of age-related changes in working memory capacity. Neurosci Lett (2005) 2.06

Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia. Hum Mol Genet (2004) 1.95

Catechol O-methyltransferase val158met genotype and neural mechanisms related to affective arousal and regulation. Arch Gen Psychiatry (2006) 1.94

Dopaminergic modulation of cortical function in patients with Parkinson's disease. Ann Neurol (2002) 1.87

Additive effects of genetic variation in dopamine regulating genes on working memory cortical activity in human brain. J Neurosci (2006) 1.85

Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling. Hum Mol Genet (2006) 1.82

Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain. Arch Gen Psychiatry (2004) 1.82

Catechol-O-methyltransferase genotype and dopamine regulation in the human brain. J Neurosci (2003) 1.82

Catechol-O-methyltransferase Val158Met modulation of prefrontal-parietal-striatal brain systems during arithmetic and temporal transformations in working memory. J Neurosci (2007) 1.81

DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms. Proc Natl Acad Sci U S A (2009) 1.76

Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study. Schizophr Res (2002) 1.76

Widespread reductions of cortical thickness in schizophrenia and spectrum disorders and evidence of heritability. Arch Gen Psychiatry (2009) 1.75

Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition. J Clin Invest (2007) 1.74

Is gray matter volume an intermediate phenotype for schizophrenia? A voxel-based morphometry study of patients with schizophrenia and their healthy siblings. Biol Psychiatry (2007) 1.73

Tolcapone improves cognition and cortical information processing in normal human subjects. Neuropsychopharmacology (2006) 1.71

Prefrontal-hippocampal coupling during memory processing is modulated by COMT val158met genotype. Biol Psychiatry (2006) 1.71

Dysfunctional prefrontal regional specialization and compensation in schizophrenia. Am J Psychiatry (2006) 1.69

Quantifying incoherence in speech: an automated methodology and novel application to schizophrenia. Schizophr Res (2007) 1.68

Association of the SerCys DISC1 polymorphism with human hippocampal formation gray matter and function during memory encoding. Eur J Neurosci (2008) 1.67

False positives in imaging genetics. Neuroimage (2007) 1.65

Dysfunctional and compensatory prefrontal cortical systems, genes and the pathogenesis of schizophrenia. Cereb Cortex (2007) 1.62

Normal age-related brain morphometric changes: nonuniformity across cortical thickness, surface area and gray matter volume? Neurobiol Aging (2010) 1.62

Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia. J Neurosci (2011) 1.61

Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Hum Mol Genet (2006) 1.61

Interactive effects of DAOA (G72) and catechol-O-methyltransferase on neurophysiology in prefrontal cortex. Biol Psychiatry (2011) 1.58

Genetic variation in KCNH2 associated with expression in the brain of a unique hERG isoform modulates treatment response in patients with schizophrenia. Am J Psychiatry (2012) 1.57

Prefrontal broadband noise, working memory, and genetic risk for schizophrenia. Am J Psychiatry (2004) 1.57

Variation of human amygdala response during threatening stimuli as a function of 5'HTTLPR genotype and personality style. Biol Psychiatry (2005) 1.55

Absence of regional brain volume change in schizophrenia associated with short-term atypical antipsychotic treatment. Schizophr Res (2007) 1.54

Schizophrenia drug says goodbye to dopamine. Nat Med (2007) 1.53

Epistasis between catechol-O-methyltransferase and type II metabotropic glutamate receptor 3 genes on working memory brain function. Proc Natl Acad Sci U S A (2007) 1.53

Amphetamine modulates human incentive processing. Neuron (2004) 1.52

Interaction of COMT (Val(108/158)Met) genotype and olanzapine treatment on prefrontal cortical function in patients with schizophrenia. Am J Psychiatry (2004) 1.51

MicroSNiPer: a web tool for prediction of SNP effects on putative microRNA targets. Hum Mutat (2010) 1.51

Brain regions underlying response inhibition and interference monitoring and suppression. Eur J Neurosci (2006) 1.51

No effect of a common allelic variant in the reelin gene on intermediate phenotype measures of brain structure, brain function, and gene expression. Biol Psychiatry (2010) 1.48

Interactive effect of apolipoprotein e genotype and age on hippocampal activation during memory processing in healthy adults. Arch Gen Psychiatry (2012) 1.48

Interplay between DISC1 and GABA signaling regulates neurogenesis in mice and risk for schizophrenia. Cell (2012) 1.48

Habit and skill learning in schizophrenia: evidence of normal striatal processing with abnormal cortical input. Learn Mem (2002) 1.48

Heritability of brain morphology related to schizophrenia: a large-scale automated magnetic resonance imaging segmentation study. Biol Psychiatry (2007) 1.45

Evidence that the BLOC-1 protein dysbindin modulates dopamine D2 receptor internalization and signaling but not D1 internalization. J Neurosci (2007) 1.44

Neural mechanisms underlying probabilistic category learning in normal aging. J Neurosci (2005) 1.43

Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans. J Clin Invest (2008) 1.43

Genetic variation in catechol-O-methyltransferase: effects on working memory in schizophrenic patients, their siblings, and healthy controls. Biol Psychiatry (2007) 1.41

Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia. J Biol Chem (2007) 1.41

Neonatal hippocampal damage alters electrophysiological properties of prefrontal cortical neurons in adult rats. Cereb Cortex (2002) 1.40

The global cognitive impairment in schizophrenia: consistent over decades and around the world. Schizophr Res (2013) 1.38

Altered cortical network dynamics: a potential intermediate phenotype for schizophrenia and association with ZNF804A. Arch Gen Psychiatry (2011) 1.38

Dopamine modulates the response of the human amygdala: a study in Parkinson's disease. J Neurosci (2002) 1.38

Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia. Hum Mol Genet (2008) 1.36

Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain. Proc Natl Acad Sci U S A (2010) 1.36

Serotonin transporter genotype (5-HTTLPR): effects of neutral and undefined conditions on amygdala activation. Biol Psychiatry (2006) 1.35