Published in Curr Opin Genet Dev on August 01, 2004
Probing the limits to positional information. Cell (2007) 6.23
Pre-steady-state decoding of the Bicoid morphogen gradient. PLoS Biol (2007) 2.81
Pattern, growth, and control. Cell (2011) 1.85
In vivo robustness analysis of cell division cycle genes in Saccharomyces cerevisiae. PLoS Genet (2006) 1.49
The measure of success: constraints, objectives, and tradeoffs in morphogen-mediated patterning. Cold Spring Harb Perspect Biol (2009) 1.10
Design principles for robust biochemical reaction networks: what works, what cannot work, and what might almost work. Math Biosci (2011) 1.06
Evolutionary tradeoffs between economy and effectiveness in biological homeostasis systems. PLoS Comput Biol (2013) 1.01
Dynamics and precision in retinoic acid morphogen gradients. Curr Opin Genet Dev (2012) 1.00
Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones. Proc Natl Acad Sci U S A (2010) 1.00
Wingless directly represses DPP morphogen expression via an armadillo/TCF/Brinker complex. PLoS One (2007) 0.99
A linear-encoding model explains the variability of the target morphology in regeneration. J R Soc Interface (2014) 0.96
Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development. Immunology (2007) 0.95
Biological systems from an engineer's point of view. PLoS Biol (2009) 0.95
Shadow Enhancers Are Pervasive Features of Developmental Regulatory Networks. Curr Biol (2015) 0.93
Models of spatially restricted biochemical reaction systems. J Biol Chem (2008) 0.92
Morphogengineering roots: comparing mechanisms of morphogen gradient formation. BMC Syst Biol (2012) 0.91
Can we build synthetic, multicellular systems by controlling developmental signaling in space and time? Curr Opin Chem Biol (2007) 0.89
The endo-siRNA pathway is essential for robust development of the Drosophila embryo. PLoS One (2009) 0.85
A switch from a gradient to a threshold mode in the regulation of a transcriptional cascade promotes robust execution of meiosis in budding yeast. PLoS One (2010) 0.83
Robust and precise morphogen-mediated patterning: trade-offs, constraints and mechanisms. J R Soc Interface (2015) 0.81
Cell-Surface Bound Nonreceptors and Signaling Morphogen Gradients. Stud Appl Math (2014) 0.81
A New Approach to Feedback for Robust Signaling Gradients. Stud Appl Math (2014) 0.80
Mechanisms of mutational robustness in transcriptional regulation. Front Genet (2015) 0.79
Particle tracking model of electrophoretic morphogen movement reveals stochastic dynamics of embryonic gradient. Dev Dyn (2009) 0.79
From cytoskeletal dynamics to organ asymmetry: a nonlinear, regulative pathway underlies left-right patterning. Philos Trans R Soc Lond B Biol Sci (2016) 0.77
A two-step patterning process increases the robustness of periodic patterning in the fly eye. J Biol Phys (2016) 0.75
Noise in protein expression scales with natural protein abundance. Nat Genet (2006) 8.03
Revealing modular organization in the yeast transcriptional network. Nat Genet (2002) 6.73
Similarities and differences in genome-wide expression data of six organisms. PLoS Biol (2003) 4.75
Robustness of the BMP morphogen gradient in Drosophila embryonic patterning. Nature (2002) 4.21
Two strategies for gene regulation by promoter nucleosomes. Genome Res (2008) 4.19
Principles of transcriptional control in the metabolic network of Saccharomyces cerevisiae. Nat Biotechnol (2003) 4.06
Mechanisms of noise-resistance in genetic oscillators. Proc Natl Acad Sci U S A (2002) 3.78
A genetic signature of interspecies variations in gene expression. Nat Genet (2006) 3.61
Defining transcription modules using large-scale gene expression data. Bioinformatics (2004) 3.33
A yeast hybrid provides insight into the evolution of gene expression regulation. Science (2009) 3.25
Rewiring of the yeast transcriptional network through the evolution of motif usage. Science (2005) 3.10
Pre-steady-state decoding of the Bicoid morphogen gradient. PLoS Biol (2007) 2.81
Iterative signature algorithm for the analysis of large-scale gene expression data. Phys Rev E Stat Nonlin Soft Matter Phys (2003) 2.51
Self-enhanced ligand degradation underlies robustness of morphogen gradients. Dev Cell (2003) 2.40
Comparative gene expression analysis by differential clustering approach: application to the Candida albicans transcription program. PLoS Genet (2005) 2.36
Scaling of the BMP activation gradient in Xenopus embryos. Nature (2008) 2.31
WIP/WASp-based actin-polymerization machinery is essential for myoblast fusion in Drosophila. Dev Cell (2007) 2.08
Noise propagation and signaling sensitivity in biological networks: a role for positive feedback. PLoS Comput Biol (2007) 1.94
Signaling mechanisms controlling cell fate and embryonic patterning. Cold Spring Harb Perspect Biol (2012) 1.89
Expansion-repression mechanism for scaling the Dpp activation gradient in Drosophila wing imaginal discs. Curr Biol (2011) 1.79
A biological solution to a fundamental distributed computing problem. Science (2011) 1.62
Variability and robustness in biomolecular systems. Mol Cell (2007) 1.61
Threshold responses to morphogen gradients by zero-order ultrasensitivity. Mol Syst Biol (2005) 1.59
Promoter architecture and the evolvability of gene expression. J Biol (2009) 1.47
Divergence of nucleosome positioning between two closely related yeast species: genetic basis and functional consequences. Mol Syst Biol (2010) 1.44
On the relation between promoter divergence and gene expression evolution. Mol Syst Biol (2008) 1.43
Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz. Genes Dev (2002) 1.41
The pattern and evolution of yeast promoter bendability. Trends Genet (2007) 1.37
Comparative analysis indicates regulatory neofunctionalization of yeast duplicates. Genome Biol (2007) 1.36
SnapShot: EGFR signaling pathway. Cell (2007) 1.35
Drosophila follicle cells are patterned by multiple levels of Notch signaling and antagonism between the Notch and JAK/STAT pathways. Development (2007) 1.33
Strategy of transcription regulation in the budding yeast. PLoS One (2007) 1.30
The evolving doublecortin (DCX) superfamily. BMC Genomics (2006) 1.29
Epigenetically-inherited centromere and neocentromere DNA replicates earliest in S-phase. PLoS Genet (2010) 1.29
Evolution of gene sequence and gene expression are not correlated in yeast. Trends Genet (2008) 1.28
Modulation of the transcription regulatory program in yeast cells committed to sporulation. Genome Biol (2006) 1.26
Comparative biology: beyond sequence analysis. Curr Opin Biotechnol (2007) 1.24
Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches. Development (2002) 1.23
Apical secretion in epithelial tubes of the Drosophila embryo is directed by the Formin-family protein Diaphanous. Dev Cell (2009) 1.21
The actin regulator N-WASp is required for muscle-cell fusion in mice. Proc Natl Acad Sci U S A (2012) 1.20
Scaling of morphogen gradients by an expansion-repression integral feedback control. Proc Natl Acad Sci U S A (2010) 1.19
Noise-mean relationship in mutated promoters. Genome Res (2012) 1.18
The design of transcription-factor binding sites is affected by combinatorial regulation. Genome Biol (2005) 1.18
Widespread remodeling of mid-coding sequence nucleosomes by Isw1. Genome Biol (2010) 1.18
MRC1-dependent scaling of the budding yeast DNA replication timing program. Genome Res (2010) 1.18
Expression noise and acetylation profiles distinguish HDAC functions. Mol Cell (2012) 1.17
Chromatin regulators as capacitors of interspecies variations in gene expression. Mol Syst Biol (2010) 1.14
Linking the signaling cascades and dynamic regulatory networks controlling stress responses. Genome Res (2012) 1.14
Common and divergent roles for members of the mouse DCX superfamily. Cell Cycle (2006) 1.13
Evaluating putative mechanisms of the mitotic spindle checkpoint. Proc Natl Acad Sci U S A (2005) 1.12
The SCAR and WASp nucleation-promoting factors act sequentially to mediate Drosophila myoblast fusion. EMBO Rep (2009) 1.11
Re-examining the stability of the Bicoid morphogen gradient. Cell (2008) 1.10
Spore germination in Saccharomyces cerevisiae: global gene expression patterns and cell cycle landmarks. Genome Biol (2007) 1.07
Unidirectional Notch signaling depends on continuous cleavage of Delta. Development (2004) 1.06
The competitive advantage of a dual-transporter system. Science (2011) 1.06
Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila. Dev Cell (2004) 1.04
Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage. EMBO J (2002) 1.04
Rhomboid cleaves Star to regulate the levels of secreted Spitz. EMBO J (2007) 1.03
Morphogen gradient formation in a complex environment: an anomalous diffusion model. Phys Rev E Stat Nonlin Soft Matter Phys (2005) 1.02
Evolution of nucleosome occupancy: conservation of global properties and divergence of gene-specific patterns. Mol Cell Biol (2011) 1.01
Apical accumulation of the Drosophila PDGF/VEGF receptor ligands provides a mechanism for triggering localized actin polymerization. Development (2004) 1.01
Conservation of expression and sequence of metabolic genes is reflected by activity across metabolic states. PLoS Comput Biol (2006) 1.00
Robust generation and decoding of morphogen gradients. Cold Spring Harb Perspect Biol (2009) 0.99
Coordination of gene expression with growth rate: a feedback or a feed-forward strategy? FEBS Lett (2009) 0.98
Error minimization in lateral inhibition circuits. Sci Signal (2010) 0.98
Scaling of morphogen gradients. Curr Opin Genet Dev (2011) 0.96
Noise resistance in the spindle assembly checkpoint. Mol Syst Biol (2006) 0.96
Bidirectional Notch activation represses fusion competence in swarming adult Drosophila myoblasts. Development (2012) 0.95
Self-organized shuttling: generating sharp dorsoventral polarity in the early Drosophila embryo. Cell (2012) 0.94
Computational verification of protein-protein interactions by orthologous co-expression. BMC Bioinformatics (2005) 0.94
Extensive divergence of yeast stress responses through transitions between induced and constitutive activation. Proc Natl Acad Sci U S A (2011) 0.93
Directing exocrine secretory vesicles to the apical membrane by actin cables generated by the formin mDia1. Proc Natl Acad Sci U S A (2013) 0.91
The actin nucleator WASp is required for myoblast fusion during adult Drosophila myogenesis. Development (2011) 0.91
Drosophila EGFR signalling is modulated by differential compartmentalization of Rhomboid intramembrane proteases. EMBO J (2008) 0.90
Apical targeting of the formin Diaphanous in Drosophila tubular epithelia. Elife (2013) 0.90
Budding yeast escape commitment to the phosphate starvation program using gene expression noise. Curr Biol (2013) 0.90
Polarized secretion of Drosophila EGFR ligand from photoreceptor neurons is controlled by ER localization of the ligand-processing machinery. PLoS Biol (2010) 0.90
Creating gradients by morphogen shuttling. Trends Genet (2013) 0.86
Autocorrelation analysis reveals widespread spatial biases in microarray experiments. BMC Genomics (2007) 0.86
Inferring regulatory mechanisms from patterns of evolutionary divergence. Mol Syst Biol (2011) 0.85
Scaling morphogen gradients during tissue growth by a cell division rule. Development (2014) 0.85
Efficiency and specificity in microRNA biogenesis. Nat Struct Mol Biol (2012) 0.85
The WASp-based actin polymerization machinery is required in somatic support cells for spermatid maturation and release. Development (2011) 0.84
Robust selection of sensory organ precursors by the Notch-Delta pathway. Curr Opin Cell Biol (2011) 0.84
Disentangling signaling gradients generated by equivalent sources. J Biol Phys (2011) 0.83
Nucleosome organization affects the sensitivity of gene expression to promoter mutations. Mol Cell (2012) 0.82
Sequential activation of ETS proteins provides a sustained transcriptional response to EGFR signaling. Development (2013) 0.82
Overexpression of mouse Mdm2 induces developmental phenotypes in Drosophila. Oncogene (2002) 0.82
Interpreting clone-mediated perturbations of morphogen profiles. Dev Biol (2005) 0.82
Branch-specific migration cues in the Drosophila tracheal system. Bioessays (2002) 0.81
Stripe provides cues synergizing with branchless to direct tracheal cell migration. Dev Biol (2002) 0.81