Published in Cell on November 30, 2007
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther (2010) 9.13
Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas. Br J Cancer (2008) 1.75
Landscape of EGFR signaling network in human cancers: biology and therapeutic response in relation to receptor subcellular locations. Cancer Lett (2012) 1.73
Beyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology. Am J Pathol (2008) 1.47
Nuclear mode of the EGFR signaling network: biology, prognostic value, and therapeutic implications. Discov Med (2010) 1.22
Widespread uncoupling between transcriptome and translatome variations after a stimulus in mammalian cells. BMC Genomics (2012) 1.12
Multipathway kinase signatures of multipotent stromal cells are predictive for osteogenic differentiation: tissue-specific stem cells. Stem Cells (2009) 1.11
EGF increases TRPM6 activity and surface expression. J Am Soc Nephrol (2008) 1.11
EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation. Proc Natl Acad Sci U S A (2010) 1.05
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells. BMC Cell Biol (2009) 1.00
STAT1 gene expression is enhanced by nuclear EGFR and HER2 via cooperation with STAT3. Mol Carcinog (2012) 0.90
Effects of IKAP/hELP1 deficiency on gene expression in differentiating neuroblastoma cells: implications for familial dysautonomia. PLoS One (2011) 0.89
Amphiregulin promotes the immunosuppressive activity of intrahepatic CD4(+) regulatory T cells to impair CD8(+) T-cell immunity against hepatitis B virus infection. Immunology (2015) 0.89
Lung cancer biomarkers, targeted therapies and clinical assays. Transl Lung Cancer Res (2015) 0.88
Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR through microtubule-dependent trafficking. Oncogene (2013) 0.87
Generation of a canine anti-EGFR (ErbB-1) antibody for passive immunotherapy in dog cancer patients. Mol Cancer Ther (2014) 0.85
Interaction of Snail and p38 mitogen-activated protein kinase results in shorter overall survival of ovarian cancer patients. Virchows Arch (2010) 0.84
Icotinib is an active treatment of non-small-cell lung cancer: a retrospective study. PLoS One (2014) 0.81
In vivo targeting of HER2-positive tumor using 2-helix affibody molecules. Amino Acids (2011) 0.81
IgE-based Immunotherapy of Cancer -A Comparative Oncology Approach. J Carcinog Mutagen (2014) 0.81
Preliminary Evidence on the Diagnostic and Molecular Role of Circulating Soluble EGFR in Non-Small Cell Lung Cancer. Int J Mol Sci (2015) 0.81
EGFR and HER2 signaling in breast cancer brain metastasis. Front Biosci (Elite Ed) (2016) 0.79
mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cells. Oncotarget (2016) 0.79
Current treatment of early breast cancer: adjuvant and neoadjuvant therapy. F1000Res (2014) 0.78
Melanoma-associated antigen expression and the efficacy of tyrosine kinase inhibitors in head and neck cancer. Oncol Lett (2015) 0.78
Targeted therapy in the treatment of malignant gliomas. Onco Targets Ther (2009) 0.78
Soluble Epidermal Growth Factor Receptors (sEGFRs) in Cancer: Biological Aspects and Clinical Relevance. Int J Mol Sci (2016) 0.77
Integrated analysis reveals that STAT3 is central to the crosstalk between HER/ErbB receptor signaling pathways in human mammary epithelial cells. Mol Biosyst (2014) 0.76
A new mitochondrial pool of cyclin E, regulated by Drp1, is linked to cell-density-dependent cell proliferation. J Cell Sci (2015) 0.76
The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors. Nat Cell Biol (2017) 0.76
ZRX1, the first EGFR inhibitor-capecitabine based combi-molecule, requires carboxylesterase-mediated hydrolysis for optimal activity. Invest New Drugs (2013) 0.76
Circulating and disseminated tumor cells: diagnostic tools and therapeutic targets in motion. Oncotarget (2016) 0.75
The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer. Cancer Metastasis Rev (2016) 0.75
Cancer pharmacogenomics, challenges in implementation, and patient-focused perspectives. Pharmgenomics Pers Med (2016) 0.75
Pluronic-based micelle encapsulation potentiates myricetin-induced cytotoxicity in human glioblastoma cells. Int J Nanomedicine (2016) 0.75
The role of epidermal growth factor receptor (EGFR) signaling in SARS coronavirus-induced pulmonary fibrosis. Antiviral Res (2017) 0.75
Robustness of the BMP morphogen gradient in Drosophila embryonic patterning. Nature (2002) 4.21
Pre-steady-state decoding of the Bicoid morphogen gradient. PLoS Biol (2007) 2.81
Self-enhanced ligand degradation underlies robustness of morphogen gradients. Dev Cell (2003) 2.40
Scaling of the BMP activation gradient in Xenopus embryos. Nature (2008) 2.31
WIP/WASp-based actin-polymerization machinery is essential for myoblast fusion in Drosophila. Dev Cell (2007) 2.08
Signaling mechanisms controlling cell fate and embryonic patterning. Cold Spring Harb Perspect Biol (2012) 1.89
Expansion-repression mechanism for scaling the Dpp activation gradient in Drosophila wing imaginal discs. Curr Biol (2011) 1.79
Variability and robustness in biomolecular systems. Mol Cell (2007) 1.61
Threshold responses to morphogen gradients by zero-order ultrasensitivity. Mol Syst Biol (2005) 1.59
Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz. Genes Dev (2002) 1.41
Elucidating mechanisms underlying robustness of morphogen gradients. Curr Opin Genet Dev (2004) 1.36
Drosophila follicle cells are patterned by multiple levels of Notch signaling and antagonism between the Notch and JAK/STAT pathways. Development (2007) 1.33
Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches. Development (2002) 1.23
Apical secretion in epithelial tubes of the Drosophila embryo is directed by the Formin-family protein Diaphanous. Dev Cell (2009) 1.21
The actin regulator N-WASp is required for muscle-cell fusion in mice. Proc Natl Acad Sci U S A (2012) 1.20
The SCAR and WASp nucleation-promoting factors act sequentially to mediate Drosophila myoblast fusion. EMBO Rep (2009) 1.11
Re-examining the stability of the Bicoid morphogen gradient. Cell (2008) 1.10
Unidirectional Notch signaling depends on continuous cleavage of Delta. Development (2004) 1.06
Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila. Dev Cell (2004) 1.04
Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage. EMBO J (2002) 1.04
Rhomboid cleaves Star to regulate the levels of secreted Spitz. EMBO J (2007) 1.03
Apical accumulation of the Drosophila PDGF/VEGF receptor ligands provides a mechanism for triggering localized actin polymerization. Development (2004) 1.01
Robust generation and decoding of morphogen gradients. Cold Spring Harb Perspect Biol (2009) 0.99
Scaling of morphogen gradients. Curr Opin Genet Dev (2011) 0.96
Bidirectional Notch activation represses fusion competence in swarming adult Drosophila myoblasts. Development (2012) 0.95
Self-organized shuttling: generating sharp dorsoventral polarity in the early Drosophila embryo. Cell (2012) 0.94
Directing exocrine secretory vesicles to the apical membrane by actin cables generated by the formin mDia1. Proc Natl Acad Sci U S A (2013) 0.91
The actin nucleator WASp is required for myoblast fusion during adult Drosophila myogenesis. Development (2011) 0.91
Drosophila EGFR signalling is modulated by differential compartmentalization of Rhomboid intramembrane proteases. EMBO J (2008) 0.90
Polarized secretion of Drosophila EGFR ligand from photoreceptor neurons is controlled by ER localization of the ligand-processing machinery. PLoS Biol (2010) 0.90
Apical targeting of the formin Diaphanous in Drosophila tubular epithelia. Elife (2013) 0.90
The WASp-based actin polymerization machinery is required in somatic support cells for spermatid maturation and release. Development (2011) 0.84
Overexpression of mouse Mdm2 induces developmental phenotypes in Drosophila. Oncogene (2002) 0.82
Sequential activation of ETS proteins provides a sustained transcriptional response to EGFR signaling. Development (2013) 0.82
Stripe provides cues synergizing with branchless to direct tracheal cell migration. Dev Biol (2002) 0.81
Branch-specific migration cues in the Drosophila tracheal system. Bioessays (2002) 0.81
Generation of distinct signaling modes via diversification of the Egfr ligand-processing cassette. Development (2010) 0.79
Scaling of dorsal-ventral patterning in the Xenopus laevis embryo. Bioessays (2013) 0.78
Making muscles: Arp, two, three. Fly (Austin) (2010) 0.77
ER retention of signaling modules. Dev Cell (2005) 0.75
Developmental biology: Segmentation within scale. Nature (2012) 0.75
Modular tubes: common principles of renal development. Curr Biol (2003) 0.75
Modeling pattern formation: counting to two in the Drosophila egg. Curr Biol (2002) 0.75
Versatility of EGF receptor ligand processing in insects. Dev Biol (2010) 0.75