Published in Curr Opin Cell Biol on August 01, 2004
The axonal transport of mitochondria. J Cell Sci (2005) 5.19
Two binding partners cooperate to activate the molecular motor Kinesin-1. J Cell Biol (2007) 2.31
The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. EMBO J (2007) 1.55
UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly. Genes Dev (2008) 1.40
The G59S mutation in p150(glued) causes dysfunction of dynactin in mice. J Neurosci (2007) 1.36
Motor number controls cargo switching at actin-microtubule intersections in vitro. Curr Biol (2010) 1.30
De novo mutations in the beta-tubulin gene TUBB2A cause simplified gyral patterning and infantile-onset epilepsy. Am J Hum Genet (2014) 1.23
Neuronal cotransport of glycine receptor and the scaffold protein gephyrin. J Cell Biol (2006) 1.22
Distinct roles of doublecortin modulating the microtubule cytoskeleton. EMBO J (2006) 1.16
Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation. J Biol Chem (2008) 1.16
Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility. EMBO J (2011) 1.13
T-cell-mediated disruption of the neuronal microtubule network: correlation with early reversible axonal dysfunction in acute experimental autoimmune encephalomyelitis. Am J Pathol (2006) 1.09
Switching of membrane organelles between cytoskeletal transport systems is determined by regulation of the microtubule-based transport. J Cell Biol (2007) 1.05
Cerebrospinal fluid-based kinetic biomarkers of axonal transport in monitoring neurodegeneration. J Clin Invest (2012) 1.05
Computational modeling of axonal microtubule bundles under tension. Biophys J (2012) 1.00
CK1 activates minus-end-directed transport of membrane organelles along microtubules. Mol Biol Cell (2011) 0.99
Modeling the signaling endosome hypothesis: why a drive to the nucleus is better than a (random) walk. Theor Biol Med Model (2005) 0.98
CD4 T cells: Balancing the coming and going of autoimmune-mediated inflammation in the CNS. Brain Behav Immun (2008) 0.97
Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin. J Biol Chem (2008) 0.96
Unc-51/ATG1 controls axonal and dendritic development via kinesin-mediated vesicle transport in the Drosophila brain. PLoS One (2011) 0.92
Mitochondrial configurations in peripheral nerve suggest differential ATP production. J Struct Biol (2010) 0.91
Development of dendrite polarity in Drosophila neurons. Neural Dev (2012) 0.90
The kinesin-3 family motor KLP-4 regulates anterograde trafficking of GLR-1 glutamate receptors in the ventral nerve cord of Caenorhabditis elegans. Mol Biol Cell (2012) 0.87
DISC1 regulates synaptic vesicle transport via a lithium-sensitive pathway. Neurosci Res (2011) 0.86
Ndel1 promotes axon regeneration via intermediate filaments. PLoS One (2008) 0.83
Lymphocytes with cytotoxic activity induce rapid microtubule axonal destabilization independently and before signs of neuronal death. ASN Neuro (2013) 0.81
The protein kinase A-anchoring protein moesin is bound to pigment granules in melanophores. Traffic (2008) 0.81
Buckling behavior of individual and bundled microtubules. Biophys J (2015) 0.78
Dysfunction of microtubule-associated proteins of MAP2/tau family in Prion disease. Prion (2012) 0.78
BMP signaling and microtubule organization regulate synaptic strength. Neuroscience (2015) 0.76
Targeting caspase-6 and caspase-8 to promote neuronal survival following ischemic stroke. Cell Death Dis (2015) 0.76
The Role of Astrocytes in Metabolism and Neurotoxicity of the Pyrrolizidine Alkaloid Monocrotaline, the Main Toxin of Crotalaria retusa. Front Pharmacol (2012) 0.75
Deciphering the Role of Emx1 in Neurogenesis: A Neuroproteomics Approach. Front Mol Neurosci (2016) 0.75
Torsional behavior of axonal microtubule bundles. Biophys J (2015) 0.75
Single molecule FRET observation of kinesin-1's head-tail interaction on microtubule. Biophysics (Nagoya-shi) (2013) 0.75
Microtubule motors: moving forward on many fronts. F1000 Biol Rep (2009) 0.75
JIP1 and JIP3 cooperate to mediate TrkB anterograde axonal transport by activating kinesin-1. Cell Mol Life Sci (2017) 0.75
TUBB2B Mutation in an Adult Patient with Myoclonus-Dystonia. Case Rep Neurol (2017) 0.75
Somatic coding mutations in human induced pluripotent stem cells. Nature (2011) 9.50
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science (2005) 5.49
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature (2012) 5.47
Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci U S A (2003) 4.47
A standardized kinesin nomenclature. J Cell Biol (2004) 4.43
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron (2003) 4.04
Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron (2006) 3.51
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes Dev (2010) 3.37
Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. PLoS One (2011) 2.74
JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Dev Cell (2003) 2.45
Sunday Driver links axonal transport to damage signaling. J Cell Biol (2005) 2.29
Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. J Cell Biol (2003) 2.02
Axonal transport and Alzheimer's disease. Annu Rev Biochem (2006) 1.98
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Proc Natl Acad Sci U S A (2008) 1.84
Sunday driver interacts with two distinct classes of axonal organelles. J Biol Chem (2009) 1.84
Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1. Hum Mol Genet (2012) 1.80
Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Mol Biol Cell (2007) 1.67
A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. Cell Stem Cell (2013) 1.59
Investigating synapse formation and function using human pluripotent stem cell-derived neurons. Proc Natl Acad Sci U S A (2011) 1.52
Principles of cargo attachment to cytoplasmic motor proteins. Curr Opin Cell Biol (2002) 1.51
The genetics of axonal transport and axonal transport disorders. PLoS Genet (2006) 1.49
Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre. Invest Ophthalmol Vis Sci (2006) 1.38
Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles. Cell (2011) 1.38
Patients beware: commercialized stem cell treatments on the web. Cell Stem Cell (2010) 1.32
Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways. Arch Neurol (2005) 1.28
Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin. J Neurosci (2008) 1.26
ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proc Natl Acad Sci U S A (2012) 1.25
Cargo-carrying motor vehicles on the neuronal highway: transport pathways and neurodegenerative disease. J Neurobiol (2004) 1.20
Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects. J Neurosci (2009) 1.16
Decellularized porcine brain matrix for cell culture and tissue engineering scaffolds. Tissue Eng Part A (2011) 1.10
Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides. Hum Mol Genet (2008) 1.06
The presenilin-1 ΔE9 mutation results in reduced γ-secretase activity, but not total loss of PS1 function, in isogenic human stem cells. Cell Rep (2013) 1.00
Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila. Mol Biol Cell (2012) 1.00
Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies. Hum Mol Genet (2010) 1.00
Examination of potential mechanisms of amyloid-induced defects in neuronal transport. Neurobiol Dis (2009) 0.98
Endogenous GSK-3/shaggy regulates bidirectional axonal transport of the amyloid precursor protein. Traffic (2013) 0.94
Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles. Proc Natl Acad Sci U S A (2012) 0.90
Biophysical challenges to axonal transport: motor-cargo deficiencies and neurodegeneration. Annu Rev Biophys (2014) 0.90
A genetic screen for suppressors and enhancers of the Drosophila cdk1-cyclin B identifies maternal factors that regulate microtubule and microfilament stability. Genetics (2002) 0.89
Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo. Hum Mol Genet (2013) 0.89
Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects. Hum Mol Genet (2012) 0.89
Alzheimer's disease in a dish: promises and challenges of human stem cell models. Hum Mol Genet (2012) 0.89
Kinesin-2 and photoreceptor cell death: requirement of motor subunits. Exp Eye Res (2005) 0.86
The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila. PLoS One (2013) 0.85
A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. Mol Biol Cell (2011) 0.80
Linking molecular motors to Alzheimer's disease. J Physiol Paris (2006) 0.79
Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function. J Cell Sci (2014) 0.78
Using human-induced pluripotent stem cells to model monogenic metabolic disorders of the liver. Semin Liver Dis (2013) 0.78
UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport. J Neurosci (2014) 0.77
Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. PLoS One (2012) 0.76
Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation. J Biol Chem (2013) 0.75