Published in J Cell Sci on February 12, 2014
Polarized sorting of the copper transporter ATP7B in neurons mediated by recognition of a dileucine signal by AP-1. Mol Biol Cell (2014) 0.81
Lrig1 is a cell-intrinsic modulator of hippocampal dendrite complexity and BDNF signaling. EMBO Rep (2016) 0.76
Visualizing K48 Ubiquitination during Presynaptic Formation By Ubiquitination-Induced Fluorescence Complementation (UiFC). Front Mol Neurosci (2016) 0.75
Mitochondrial dynamics in Parkinson's disease: a role for α-synuclein? Dis Model Mech (2017) 0.75
Somatic coding mutations in human induced pluripotent stem cells. Nature (2011) 9.50
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science (2005) 5.49
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature (2012) 5.47
Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci U S A (2003) 4.47
A standardized kinesin nomenclature. J Cell Biol (2004) 4.43
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron (2003) 4.04
Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron (2006) 3.51
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes Dev (2010) 3.37
Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. PLoS One (2011) 2.74
JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Dev Cell (2003) 2.45
Sunday Driver links axonal transport to damage signaling. J Cell Biol (2005) 2.29
Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. J Cell Biol (2003) 2.02
Axonal transport and Alzheimer's disease. Annu Rev Biochem (2006) 1.98
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Proc Natl Acad Sci U S A (2008) 1.84
Sunday driver interacts with two distinct classes of axonal organelles. J Biol Chem (2009) 1.84
Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1. Hum Mol Genet (2012) 1.80
Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Mol Biol Cell (2007) 1.67
A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. Cell Stem Cell (2013) 1.59
Investigating synapse formation and function using human pluripotent stem cell-derived neurons. Proc Natl Acad Sci U S A (2011) 1.52
Microtubule-dependent transport in neurons: steps towards an understanding of regulation, function and dysfunction. Curr Opin Cell Biol (2004) 1.51
Principles of cargo attachment to cytoplasmic motor proteins. Curr Opin Cell Biol (2002) 1.51
The genetics of axonal transport and axonal transport disorders. PLoS Genet (2006) 1.49
Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre. Invest Ophthalmol Vis Sci (2006) 1.38
Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles. Cell (2011) 1.38
Patients beware: commercialized stem cell treatments on the web. Cell Stem Cell (2010) 1.32
Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways. Arch Neurol (2005) 1.28
Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin. J Neurosci (2008) 1.26
ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proc Natl Acad Sci U S A (2012) 1.25
Cargo-carrying motor vehicles on the neuronal highway: transport pathways and neurodegenerative disease. J Neurobiol (2004) 1.20
Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects. J Neurosci (2009) 1.16
Decellularized porcine brain matrix for cell culture and tissue engineering scaffolds. Tissue Eng Part A (2011) 1.10
Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides. Hum Mol Genet (2008) 1.06
Quantitative single particle tracking of NGF-receptor complexes: transport is bidirectional but biased by longer retrograde run lengths. FEBS Lett (2007) 1.02
A model-independent algorithm to derive Ca2+ fluxes underlying local cytosolic Ca2+ transients. Biophys J (2005) 1.01
Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies. Hum Mol Genet (2010) 1.00
The presenilin-1 ΔE9 mutation results in reduced γ-secretase activity, but not total loss of PS1 function, in isogenic human stem cells. Cell Rep (2013) 1.00
Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila. Mol Biol Cell (2012) 1.00
Examination of potential mechanisms of amyloid-induced defects in neuronal transport. Neurobiol Dis (2009) 0.98
Endogenous GSK-3/shaggy regulates bidirectional axonal transport of the amyloid precursor protein. Traffic (2013) 0.94
Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles. Proc Natl Acad Sci U S A (2012) 0.90
Biophysical challenges to axonal transport: motor-cargo deficiencies and neurodegeneration. Annu Rev Biophys (2014) 0.90
Alzheimer's disease in a dish: promises and challenges of human stem cell models. Hum Mol Genet (2012) 0.89
Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo. Hum Mol Genet (2013) 0.89
Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects. Hum Mol Genet (2012) 0.89
A genetic screen for suppressors and enhancers of the Drosophila cdk1-cyclin B identifies maternal factors that regulate microtubule and microfilament stability. Genetics (2002) 0.89
Kinesin-2 and photoreceptor cell death: requirement of motor subunits. Exp Eye Res (2005) 0.86
The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila. PLoS One (2013) 0.85
Simple data-driven models of intracellular calcium dynamics with predictive power. Phys Rev E Stat Nonlin Soft Matter Phys (2006) 0.83
Anomalous dynamics of melanosomes driven by myosin-V in Xenopus laevis melanophores. Biophys J (2009) 0.83
A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. Mol Biol Cell (2011) 0.80
Linking molecular motors to Alzheimer's disease. J Physiol Paris (2006) 0.79
Using human-induced pluripotent stem cells to model monogenic metabolic disorders of the liver. Semin Liver Dis (2013) 0.78
UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport. J Neurosci (2014) 0.77
Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. PLoS One (2012) 0.76
Extracting the stepping dynamics of molecular motors in living cells from trajectories of single particles. Cell Biochem Biophys (2013) 0.76
When size does matter: organelle size influences the properties of transport mediated by molecular motors. Biochim Biophys Acta (2013) 0.76
Temperature response of luminescent tris(bipyridine)ruthenium(II)-doped silica nanoparticles. J Colloid Interface Sci (2012) 0.76
Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation. J Biol Chem (2013) 0.75
Transport properties of melanosomes along microtubules interpreted by a tug-of-war model with loose mechanical coupling. PLoS One (2012) 0.75
Correction: Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality. Elife (2016) 0.75
Diffusion of single dye molecules in hydrated TiO2 mesoporous films. Phys Chem Chem Phys (2017) 0.75