Published in Infect Immun on August 01, 2004
Distinct roles for IL-6 and IL-12p40 in mediating protection against Leishmania donovani and the expansion of IL-10+ CD4+ T cells. Eur J Immunol (2006) 1.44
Modulation of dendritic cell function by Leishmania parasites. J Immunol (2008) 1.40
Role of interleukin-1beta in activating the CD11c(high) CD45RB- dendritic cell subset and priming Leishmania amazonensis-specific CD4+ T cells in vitro and in vivo. Infect Immun (2007) 1.13
Development of Vaccines against Visceral Leishmaniasis. J Trop Med (2011) 1.03
Role of natural killer cells in modulating dendritic cell responses to Leishmania amazonensis infection. Infect Immun (2008) 0.95
Antigen-responsive CD4+ T cells from C3H mice chronically infected with Leishmania amazonensis are impaired in the transition to an effector phenotype. Infect Immun (2006) 0.92
Effects of CXCL10 on dendritic cell and CD4+ T-cell functions during Leishmania amazonensis infection. Infect Immun (2007) 0.90
Reactive oxygen species and nitric oxide in cutaneous leishmaniasis. J Parasitol Res (2012) 0.89
A deficiency in the B cell response of C57BL/6 mice correlates with loss of macrophage-mediated killing of Leishmania amazonensis. Int J Parasitol (2009) 0.86
An in vitro model of antibody-enhanced killing of the intracellular parasite Leishmania amazonensis. PLoS One (2014) 0.85
IL-2 limits IL-12 enhanced lymphocyte proliferation during Leishmania amazonensis infection. Cell Immunol (2011) 0.76
Dendritic cells and the control of immunity. Nature (1998) 56.54
Real time quantitative PCR. Genome Res (1996) 35.79
An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods (1999) 17.06
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell (1997) 12.68
Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science (2002) 8.34
The regulation of immunity to Leishmania major. Annu Rev Immunol (1995) 8.05
The immunology of susceptibility and resistance to Leishmania major in mice. Nat Rev Immunol (2002) 6.59
Dendritic cell regulation of TH1-TH2 development. Nat Immunol (2000) 5.13
Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells. Science (2000) 4.03
Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity. J Exp Med (1998) 2.30
CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major. J Immunol (2002) 2.16
Differential production of Th1- and Th2-derived cytokines does not determine the genetically controlled or vaccine-induced rate of cure in murine visceral leishmaniasis. J Immunol (1991) 2.00
Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis. Infect Immun (1993) 2.00
Prophylactic immunization against experimental leishmaniasis: I. Protection induced in mice genetically vulnerable to fatal Leishmania tropica infection. J Immunol (1982) 1.89
Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen-specific T cells. Eur J Immunol (1993) 1.88
Impaired expression of inflammatory cytokines and chemokines at early stages of infection with Leishmania amazonensis. Infect Immun (2003) 1.74
Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection. J Immunol (1997) 1.62
IL-4-independent inhibition of IL-12 responsiveness during Leishmania amazonensis infection. J Immunol (2000) 1.54
Dendritic cells in Leishmania major-immune mice harbor persistent parasites and mediate an antigen-specific T cell immune response. Eur J Immunol (1995) 1.54
Early enhanced Th1 response after Leishmania amazonensis infection of C57BL/6 interleukin-10-deficient mice does not lead to resolution of infection. Infect Immun (2002) 1.54
IL-12 is required to maintain a Th1 response during Leishmania major infection. J Immunol (2000) 1.45
Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis. Nat Immunol (2002) 1.44
Leishmania pifanoi amastigote antigens protect mice against cutaneous leishmaniasis. Infect Immun (1995) 1.44
Local suppression of IFN-gamma in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi. J Immunol (1996) 1.39
Leishmania amazonensis-dendritic cell interactions in vitro and the priming of parasite-specific CD4(+) T cells in vivo. J Immunol (2001) 1.36
Leishmania major-infected murine langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis. Eur J Immunol (2000) 1.36
Enhanced replication of Leishmania amazonensis amastigotes in gamma interferon-stimulated murine macrophages: implications for the pathogenesis of cutaneous leishmaniasis. Infect Immun (2004) 1.33
Silent infection of bone marrow-derived dendritic cells by Leishmania mexicana amastigotes. Eur J Immunol (2001) 1.18
Mechanisms of pathogenesis: differences amongst Leishmania species. Trans R Soc Trop Med Hyg (2002) 1.17
Late metastatic Leishmaniasis in the mouse. A model for mucocutaneous disease. Am J Trop Med Hyg (1983) 1.16
Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major. Eur J Immunol (1998) 1.16
Dendritic cell (DC)-based protection against an intracellular pathogen is dependent upon DC-derived IL-12 and can be induced by molecularly defined antigens. J Immunol (2003) 1.14
Leishmania parasites and their ploys to disrupt macrophage activation. Curr Opin Hematol (2000) 1.13
DNA immunization with the gene encoding P4 nuclease of Leishmania amazonensis protects mice against cutaneous Leishmaniasis. Infect Immun (2003) 1.09
Leishmania priming of human dendritic cells for CD40 ligand-induced interleukin-12p70 secretion is strain and species dependent. Infect Immun (2002) 1.08
Differential regulation of the interleukin-12 receptor during the innate immune response to Leishmania major. Infect Immun (1998) 1.08
Inbred mice as model hosts for cutaneous leishmaniasis. I. Resistance and susceptibility to infection with Leishmania braziliensis, L. mexicana, and L. aethiopica. Ann Trop Med Parasitol (1984) 1.06
Antigen presentation capacity of murine macrophages infected with Leishmania amazonensis amastigotes. J Immunol (1993) 1.06
Leishmania-infected macrophages sequester endogenously synthesized parasite antigens from presentation to CD4+ T cells. Eur J Immunol (1996) 1.05
Genetic analysis of Leishmania mexicana infection in mice: single gene (Scl-2) controlled predisposition to cutaneous lesion development. J Immunogenet (1990) 1.02
A dhfr-ts- Leishmania major knockout mutant cross-protects against Leishmania amazonensis. Mem Inst Oswaldo Cruz (1999) 0.94
In vivo protective effect of the lectin from Canavalia brasiliensis on BALB/c mice infected by Leishmania amazonensis. Acta Trop (1996) 0.90
Host susceptibility factors to cutaneous leishmaniasis. Front Biosci (1998) 0.88
Interferon-gamma-inducing oral vaccination with Leishmania amazonensis antigens protects BALB/c and C57BL/6 mice against cutaneous leishmaniasis. Vaccine (2003) 0.86
Maintenance of IL-12-responsive CD4+ T cells during a Th2 response in Leishmania major-infected mice. Eur J Immunol (2000) 0.84
Spatial analysis of arabidopsis thaliana gene expression in response to Turnip mosaic virus infection. Mol Plant Microbe Interact (2007) 1.23
Macrophage killing of Leishmania amazonensis amastigotes requires both nitric oxide and superoxide. Am J Trop Med Hyg (2007) 1.20
Programmed death 1-mediated T cell exhaustion during visceral leishmaniasis impairs phagocyte function. J Immunol (2013) 1.14
Immunologic indicators of clinical progression during canine Leishmania infantum infection. Clin Vaccine Immunol (2009) 1.02
Altered dendritic cell phenotype in response to Leishmania amazonensis amastigote infection is mediated by MAP kinase, ERK. Am J Pathol (2009) 0.96
Parameter estimation and sensitivity analysis in an agent-based model of Leishmania major infection. J Theor Biol (2009) 0.93
Antigen-responsive CD4+ T cells from C3H mice chronically infected with Leishmania amazonensis are impaired in the transition to an effector phenotype. Infect Immun (2006) 0.92
Protection of C3HeB/FeJ mice against Leishmania amazonensis challenge after previous Leishmania major infection. Am J Trop Med Hyg (2004) 0.91
Soluble factors from Leishmania major-specific CD4+T cells and B cells limit L. amazonensis amastigote survival within infected macrophages. Microbes Infect (2006) 0.89
The immunology of Leishmania infection and the implications for vaccine development. Ann N Y Acad Sci (2004) 0.87
A deficiency in the B cell response of C57BL/6 mice correlates with loss of macrophage-mediated killing of Leishmania amazonensis. Int J Parasitol (2009) 0.86
Inflammation in response to n3 fatty acids in a porcine obesity model. Comp Med (2012) 0.84
Promotion of a functional B cell germinal center response after Leishmania species co-infection is associated with lesion resolution. Am J Pathol (2012) 0.84
Phase II, multicenter, open-label, randomized study of YM155 plus docetaxel as first-line treatment in patients with HER2-negative metastatic breast cancer. Breast Cancer Res Treat (2014) 0.83
Failure of antigen-stimulated gammadelta T cells and CD4+ T cells from sensitized cattle to upregulate nitric oxide and mycobactericidal activity of autologous Mycobacterium avium subsp. paratuberculosis-infected macrophages. Vet Immunol Immunopathol (2007) 0.83
Alloimmune neonatal neutropenia and neonatal isoerythrolysis in a Thoroughbred colt. J Vet Diagn Invest (2011) 0.82
Investigation of antigen-specific T-cell responses and subcutaneous granuloma development during experimental sensitization of calves with Mycobacterium avium subsp paratuberculosis. Am J Vet Res (2005) 0.81
Effect of endotoxic mastitis on epithelial cell numbers in the milk of dairy cows. Am J Vet Res (2009) 0.79
Limited susceptibility of three different mouse (Mus musculus) lines to Porcine circovirus-2 infection and associated lesions. Can J Vet Res (2009) 0.77
IL-2 limits IL-12 enhanced lymphocyte proliferation during Leishmania amazonensis infection. Cell Immunol (2011) 0.76
Ultrastructural and fluorochromatic changes of Anaplasma marginale exposed to oxytetracycline, imidocarb and enrofloxacin in short-term erythrocyte cultures. Vet Microbiol (2008) 0.75