Published in Comp Med on December 01, 2012
Disconnect between adipose tissue inflammation and cardiometabolic dysfunction in Ossabaw pigs. Obesity (Silver Spring) (2015) 1.26
Adult porcine genome-wide DNA methylation patterns support pigs as a biomedical model. BMC Genomics (2015) 0.92
Unique transcriptomic signature of omental adipose tissue in Ossabaw swine: a model of childhood obesity. Physiol Genomics (2014) 0.85
Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity. J Diabetes Res (2015) 0.81
Energy dense, protein restricted diet increases adiposity and perturbs metabolism in young, genetically lean pigs. PLoS One (2013) 0.76
Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals. J Transl Med (2015) 0.75
An Immunomodulatory Device Improves Insulin Resistance in Obese Porcine Model of Metabolic Syndrome. J Diabetes Res (2016) 0.75
A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem (1957) 173.99
Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia (1985) 109.13
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest (2003) 32.01
TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest (2006) 17.49
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med (2002) 14.15
Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest (2007) 8.71
Origins and evolution of the Western diet: health implications for the 21st century. Am J Clin Nutr (2005) 6.50
Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res (1986) 6.42
Retracted Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance. Diabetes (2007) 5.67
Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors. Immunity (2010) 5.43
Pathogenesis of type 2 diabetes mellitus. Med Clin North Am (2004) 4.44
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci U S A (2002) 4.40
Migratory fate and differentiation of blood monocyte subsets. Immunobiology (2006) 4.30
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production. Int J Obes (Lond) (2007) 2.92
Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids. Diabetologia (2006) 2.88
Remodeling phenotype of human subcutaneous adipose tissue macrophages. Circulation (2008) 2.38
Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity. Diabetes (2010) 2.35
Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat. Obesity (Silver Spring) (2008) 2.32
Palmitate activates the NF-kappaB transcription factor and induces IL-6 and TNFalpha expression in 3T3-L1 adipocytes. J Nutr (2005) 2.20
Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications. Diabetologia (2004) 2.08
Components of metabolic syndrome and coronary artery disease in female Ossabaw swine fed excess atherogenic diet. Comp Med (2006) 2.04
Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw miniature swine. Hepatology (2009) 1.78
Multiple abnormalities of myocardial insulin signaling in a porcine model of diet-induced obesity. Am J Physiol Heart Circ Physiol (2009) 1.68
Metabolic syndrome and coronary artery disease in Ossabaw compared with Yucatan swine. Comp Med (2010) 1.61
Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects. Arterioscler Thromb Vasc Biol (2007) 1.60
Polyunsaturated fatty acids of marine origin induce adiponectin in mice fed a high-fat diet. Diabetologia (2006) 1.57
The correlation between adiposity and adiponectin, tumor necrosis factor alpha, interleukin-6 and high sensitivity C-reactive protein levels. Is adipocyte size associated with inflammation in adults? J Endocrinol Invest (2007) 1.56
Adiponectin translation is increased by the PPARgamma agonists pioglitazone and omega-3 fatty acids. Am J Physiol Endocrinol Metab (2008) 1.33
Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation. J Nutr (2010) 1.26
The influence of different fats and fatty acids on obesity, insulin resistance and inflammation. J Nutr (2002) 1.06
Docosahexaenoic acid increases cellular adiponectin mRNA and secreted adiponectin protein, as well as PPARγ mRNA, in 3T3-L1 adipocytes. Appl Physiol Nutr Metab (2010) 1.02
Purified eicosapentaenoic acid reduces small dense LDL, remnant lipoprotein particles, and C-reactive protein in metabolic syndrome. Diabetes Care (2007) 1.01
Dietary intervention-induced weight loss decreases macrophage content in adipose tissue of obese women. Int J Obes (Lond) (2010) 0.99
Type I diabetes leads to tissue-specific DNA hypomethylation in male rats. J Nutr (2008) 0.99
A minipig model of high-fat/high-sucrose diet-induced diabetes and atherosclerosis. Int J Exp Pathol (2004) 0.94
Insulin and growth hormone in lean and obese pigs. Am J Physiol (1977) 0.84
n-3 PUFA attenuate lipopolysaccharide-induced down-regulation of toll-like receptor 4 expression in porcine adipose tissue but does not alter the expression of other immune modulators. J Nutr Biochem (2007) 0.81
Insulin induced growth hormone response in fast-growing, lean and in slow-growing, obese pigs. Growth (1980) 0.79
Adiponectin differentially regulates cytokines in porcine macrophages. Biochem Biophys Res Commun (2004) 2.32
Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat. Obesity (Silver Spring) (2008) 2.32
Adiponectin inhibits LPS-induced NF-kappaB activation and IL-6 production and increases PPARgamma2 expression in adipocytes. Am J Physiol Regul Integr Comp Physiol (2004) 1.62
Interleukin-6 and interleukin-15 are selectively regulated by lipopolysaccharide and interferon-gamma in primary pig adipocytes. Am J Physiol Regul Integr Comp Physiol (2003) 1.28
Macrophage killing of Leishmania amazonensis amastigotes requires both nitric oxide and superoxide. Am J Trop Med Hyg (2007) 1.20
Programmed death 1-mediated T cell exhaustion during visceral leishmaniasis impairs phagocyte function. J Immunol (2013) 1.14
Absence of Tlr2 protects against high-fat diet-induced inflammation and results in greater insulin-stimulated glucose transport in cultured adipocytes. J Nutr Biochem (2011) 1.08
Estrogen and Myc negatively regulate expression of the EphA2 tyrosine kinase. J Cell Biochem (2002) 1.05
Immunologic indicators of clinical progression during canine Leishmania infantum infection. Clin Vaccine Immunol (2009) 1.02
CD4+ Th1 cells induced by dendritic cell-based immunotherapy in mice chronically infected with Leishmania amazonensis do not promote healing. Infect Immun (2004) 0.96
Heat stress reduces intestinal barrier integrity and favors intestinal glucose transport in growing pigs. PLoS One (2013) 0.95
Parameter estimation and sensitivity analysis in an agent-based model of Leishmania major infection. J Theor Biol (2009) 0.93
Antigen-responsive CD4+ T cells from C3H mice chronically infected with Leishmania amazonensis are impaired in the transition to an effector phenotype. Infect Immun (2006) 0.92
Protection of C3HeB/FeJ mice against Leishmania amazonensis challenge after previous Leishmania major infection. Am J Trop Med Hyg (2004) 0.91
Direct regulation of lipolysis by interleukin-15 in primary pig adipocytes. Am J Physiol Regul Integr Comp Physiol (2004) 0.90
Soluble factors from Leishmania major-specific CD4+T cells and B cells limit L. amazonensis amastigote survival within infected macrophages. Microbes Infect (2006) 0.89
The immunology of Leishmania infection and the implications for vaccine development. Ann N Y Acad Sci (2004) 0.87
Inhibition of Na/K-ATPase promotes myocardial tumor necrosis factor-alpha protein expression and cardiac dysfunction via calcium/mTOR signaling in endotoxemia. Basic Res Cardiol (2012) 0.86
A deficiency in the B cell response of C57BL/6 mice correlates with loss of macrophage-mediated killing of Leishmania amazonensis. Int J Parasitol (2009) 0.86
Leptin regulation of lipid homeostasis: dietary and metabolic implications. Nutr Res Rev (2003) 0.86
Evaluation of the treatment of vancomycin-resistant enterococcal urinary tract infections in a large academic medical center. Ann Pharmacother (2013) 0.85
In utero and postnatal exposure to long chain (n-3) PUFA enhances intestinal glucose absorption and energy stores in weanling pigs. J Nutr (2007) 0.84
Effect of pH, temperature, and salt on the stability of Escherichia coli- and Chinese hamster ovary cell-derived IgG1 Fc. Biochemistry (2012) 0.84
Feeding long-chain n-3 polyunsaturated fatty acids during gestation increases intestinal glucose absorption potentially via the acute activation of AMPK. J Nutr Biochem (2008) 0.84
Promotion of a functional B cell germinal center response after Leishmania species co-infection is associated with lesion resolution. Am J Pathol (2012) 0.84
Failure of antigen-stimulated gammadelta T cells and CD4+ T cells from sensitized cattle to upregulate nitric oxide and mycobactericidal activity of autologous Mycobacterium avium subsp. paratuberculosis-infected macrophages. Vet Immunol Immunopathol (2007) 0.83
Regulation of hepatic glucose metabolism by leptin in pig and rat primary hepatocyte cultures. Am J Physiol Regul Integr Comp Physiol (2003) 0.83
Alloimmune neonatal neutropenia and neonatal isoerythrolysis in a Thoroughbred colt. J Vet Diagn Invest (2011) 0.82
Intracoronary adiponectin at reperfusion reduces infarct size in a porcine myocardial infarction model. Int J Mol Med (2011) 0.82
n-3 PUFA attenuate lipopolysaccharide-induced down-regulation of toll-like receptor 4 expression in porcine adipose tissue but does not alter the expression of other immune modulators. J Nutr Biochem (2007) 0.81
Effect of a mitochondria-targeted vitamin E derivative on mitochondrial alteration and systemic oxidative stress in mice. Br J Nutr (2011) 0.81
Investigation of antigen-specific T-cell responses and subcutaneous granuloma development during experimental sensitization of calves with Mycobacterium avium subsp paratuberculosis. Am J Vet Res (2005) 0.81
A multiplexed hybrid LC-MS/MS pharmacokinetic assay to measure two co-administered monoclonal antibodies in a clinical study. Bioanalysis (2014) 0.80
Myostatin null mice respond differently to dietary-induced and genetic obesity. Anim Sci J (2010) 0.80
Effect of endotoxic mastitis on epithelial cell numbers in the milk of dairy cows. Am J Vet Res (2009) 0.79
Effects of mammalian in utero heat stress on adolescent body temperature. Int J Hyperthermia (2013) 0.79
Early lesion formation in colorectal carcinogenesis is associated with adiponectin status whereas neoplastic lesions are associated with diet and sex in C57BL/6J mice. Nutr Cancer (2011) 0.79
A mitochondria-targeted vitamin E derivative decreases hepatic oxidative stress and inhibits fat deposition in mice. J Nutr (2010) 0.79
Chronic leptin administration increases serum NEFA in the pig and differentially regulates PPAR expression in adipose tissue. J Nutr Biochem (2003) 0.78
Regulation of tie2 expression by angiopoietin--potential feedback system. Endothelium (2004) 0.78
Rapid Diagnosis of Trichomonas vaginalis by Testing Vaginal Swabs in an Isothermal Helicase-Dependent AmpliVue Assay. Sex Transm Dis (2016) 0.78
Ease, Comfort, and Performance of the HerSwab Vaginal Self-Sampling Device for the Detection of Chlamydia trachomatis and Neisseria gonorrhoeae. Sex Transm Dis (2016) 0.77
Low-dose dietary resveratrol has differential effects on colorectal tumorigenesis in adiponectin knockout and wild-type mice. Nutr Cancer (2011) 0.77
Limited susceptibility of three different mouse (Mus musculus) lines to Porcine circovirus-2 infection and associated lesions. Can J Vet Res (2009) 0.77
The regulation of IGF-1 by leptin in the pig is tissue specific and independent of changes in growth hormone. J Nutr Biochem (2003) 0.77
Technical decision making with higher order structure data: higher order structure characterization during protein therapeutic candidate screening. J Pharm Sci (2015) 0.77
IL-2 limits IL-12 enhanced lymphocyte proliferation during Leishmania amazonensis infection. Cell Immunol (2011) 0.76
Ultrastructural and fluorochromatic changes of Anaplasma marginale exposed to oxytetracycline, imidocarb and enrofloxacin in short-term erythrocyte cultures. Vet Microbiol (2008) 0.75
Isochromosome 17q; A Novel Finding in Myeloid Sarcoma. J Clin Exp Hematop (2016) 0.75
High-throughput chemical modification of oligonucleotides for systematic structure-activity relationship evaluation. Bioconjug Chem (2014) 0.75
The design, preparation and SAR of novel small molecule sodium (Na(+)) channel blockers. Bioorg Med Chem Lett (2004) 0.75