Published in Development on July 27, 2004
Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells. Cell (2009) 3.75
The hairless mouse in skin research. J Dermatol Sci (2008) 1.95
Caspase-14 reveals its secrets. J Cell Biol (2008) 1.47
Hairless triggers reactivation of hair growth by promoting Wnt signaling. Proc Natl Acad Sci U S A (2005) 1.41
Vitamin D metabolism and function in the skin. Mol Cell Endocrinol (2011) 1.40
The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging. J Steroid Biochem Mol Biol (2010) 1.34
Exploiting the keratin 17 gene promoter to visualize live cells in epithelial appendages of mice. Mol Cell Biol (2005) 1.14
Corepressors of agonist-bound nuclear receptors. Toxicol Appl Pharmacol (2007) 1.08
Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice. J Cell Physiol (2010) 1.05
Vitamin D and the skin: Physiology and pathophysiology. Rev Endocr Metab Disord (2012) 1.03
Vitamin D and the skin. J Bone Miner Metab (2010) 1.03
Immune competency of a hairless mouse strain for improved preclinical studies in genetically engineered mice. Mol Cancer Ther (2010) 1.00
Loss of hairless confers susceptibility to UVB-induced tumorigenesis via disruption of NF-kappaB signaling. PLoS One (2012) 0.94
Hairless is a nuclear receptor corepressor essential for skin function. Nucl Recept Signal (2009) 0.93
Lymphoid enhancer-binding factor-1 (LEF1) interacts with the DNA-binding domain of the vitamin D receptor. J Biol Chem (2011) 0.91
Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins. BMC Genomics (2008) 0.85
Molecular basis for hair loss in mice carrying a novel nonsense mutation (Hrrh-R ) in the hairless gene (Hr). Vet Pathol (2010) 0.84
Hairless is a histone H3K9 demethylase. FASEB J (2013) 0.84
A humanized mouse model of hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia. Endocrinology (2014) 0.84
Hairless plays a role in formation of inner root sheath via regulation of Dlx3 gene. J Biol Chem (2012) 0.82
Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle. J Cell Biochem (2010) 0.81
Gene expression profile of the skin in the 'hairpoor' (HrHp) mice by microarray analysis. BMC Genomics (2010) 0.80
Genome-wide search reveals the existence of a limited number of thyroid hormone receptor alpha target genes in cerebellar neurons. PLoS One (2012) 0.79
Structural changes in hair follicles and sebaceous glands of hairless mice following exposure to sulfur mustard. Exp Mol Pathol (2014) 0.78
Vitamin D receptor-mediated control of Soggy, Wise, and Hairless gene expression in keratinocytes. J Endocrinol (2014) 0.75
Merkel cells are long-lived cells whose production is stimulated by skin injury. Dev Biol (2016) 0.75
Hair lost in translation. Nat Genet (2009) 0.75
Hairless expression attenuates apoptosis in a mouse model and the COS cell line; involvement of p53. PLoS One (2010) 0.75
A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. Nature (2006) 3.28
New consensus nomenclature for mammalian keratins. J Cell Biol (2006) 3.27
Contribution of olfactory neural stem cells to tissue maintenance and regeneration. Nat Neurosci (2007) 3.12
Intermediate filament proteins and their associated diseases. N Engl J Med (2004) 2.84
MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription. Genes Dev (2004) 2.07
Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm. Genes Dev (2007) 2.02
Keratin 16-null mice develop palmoplantar keratoderma, a hallmark feature of pachyonychia congenita and related disorders. J Invest Dermatol (2012) 1.72
Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin. Nat Genet (2010) 1.63
Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair. J Cell Biol (2003) 1.58
Ligand-independent actions of the vitamin D receptor maintain hair follicle homeostasis. Mol Endocrinol (2004) 1.56
Overexpressed transient receptor potential vanilloid 3 ion channels in skin keratinocytes modulate pain sensitivity via prostaglandin E2. J Neurosci (2008) 1.53
Keratin 17 null mice exhibit age- and strain-dependent alopecia. Genes Dev (2002) 1.47
A mouse model of androgenetic alopecia. Endocrinology (2010) 1.46
Hairless triggers reactivation of hair growth by promoting Wnt signaling. Proc Natl Acad Sci U S A (2005) 1.41
Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling. J Biol Chem (2003) 1.41
The expanding significance of keratin intermediate filaments in normal and diseased epithelia. Curr Opin Cell Biol (2012) 1.36
Emerging role for the cytoskeleton as an organizer and regulator of translation. Nat Rev Mol Cell Biol (2010) 1.35
Keratin function in skin epithelia: a broadening palette with surprising shades. Curr Opin Cell Biol (2006) 1.34
Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex. Proc Natl Acad Sci U S A (2007) 1.34
Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion. Genes Dev (2006) 1.26
Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle. J Invest Dermatol (2002) 1.19
Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments. Mol Biol Cell (2002) 1.17
Novel mechanism of nuclear receptor corepressor interaction dictated by activation function 2 helix determinants. Mol Cell Biol (2002) 1.17
Keratin 16 regulates innate immunity in response to epidermal barrier breach. Proc Natl Acad Sci U S A (2013) 1.16
Exploiting the keratin 17 gene promoter to visualize live cells in epithelial appendages of mice. Mol Cell Biol (2005) 1.14
Self-organization of keratin intermediate filaments into cross-linked networks. J Cell Biol (2009) 1.12
The mechanical properties of simple epithelial keratins 8 and 18: discriminating between interfacial and bulk elasticities. J Struct Biol (2003) 1.11
Type II epithelial keratin 6hf (K6hf) is expressed in the companion layer, matrix, and medulla in anagen-stage hair follicles. J Invest Dermatol (2003) 1.11
An ex vivo assay to assess the potential of skin keratinocytes for wound epithelialization. J Invest Dermatol (2002) 1.11
Interaction between the keratin cytoskeleton and eEF1Bgamma affects protein synthesis in epithelial cells. Nat Struct Mol Biol (2007) 1.11
Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. Nat Struct Mol Biol (2012) 1.10
Differential modulation of keratin expression by sulforaphane occurs via Nrf2-dependent and -independent pathways in skin epithelia. Mol Biol Cell (2010) 1.10
The thyroid hormone-regulated corepressor hairless associates with histone deacetylases in neonatal rat brain. Mol Endocrinol (2002) 1.09
A small surface hydrophobic stripe in the coiled-coil domain of type I keratins mediates tetramer stability. J Cell Biol (2005) 1.09
Hairless and Wnt signaling: allies in epithelial stem cell differentiation. Cell Cycle (2006) 1.08
Networking galore: intermediate filaments and cell migration. Curr Opin Cell Biol (2013) 1.07
Role for keratins 6 and 17 during wound closure in embryonic mouse skin. Dev Dyn (2003) 1.07
Intermediate filaments and tissue repair. Exp Cell Res (2004) 1.04
Research Resource: The androgen receptor modulates expression of genes with critical roles in muscle development and function. Mol Endocrinol (2010) 1.03
A wound-induced keratin inhibits Src activity during keratinocyte migration and tissue repair. J Cell Biol (2012) 1.01
Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles. J Invest Dermatol (2006) 1.00
A novel mouse type I intermediate filament gene, keratin 17n (K17n), exhibits preferred expression in nail tissue. J Invest Dermatol (2004) 1.00
Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice. Mol Cell Biol (2005) 0.99
A unique insertion/duplication in the VDR gene that truncates the VDR causing hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia. Arch Biochem Biophys (2006) 0.98
Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile. FASEB J (2007) 0.96
Hedgehog signaling, keratin 6 induction, and sebaceous gland morphogenesis: implications for pachyonychia congenita and related conditions. Am J Pathol (2008) 0.95
Barrier function in transgenic mice overexpressing K16, involucrin, and filaggrin in the suprabasal epidermis. J Invest Dermatol (2004) 0.92
Periderm prevents pathological epithelial adhesions during embryogenesis. J Clin Invest (2014) 0.91
Liver X receptor is a therapeutic target for photoaging and chronological skin aging. Mol Endocrinol (2008) 0.90
Skin: an ideal model system to study keratin genes and proteins. Methods Cell Biol (2004) 0.89
Liver X receptor-retinoid X receptor (LXR-RXR) heterodimer cistrome reveals coordination of LXR and AP1 signaling in keratinocytes. J Biol Chem (2011) 0.89
Estrogen receptor beta is a novel therapeutic target for photoaging. Mol Pharmacol (2010) 0.89
Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion. J Biol Chem (2011) 0.87
Defining the properties of the nonhelical tail domain in type II keratin 5: insight from a bullous disease-causing mutation. Mol Biol Cell (2005) 0.86
Identification of novel interaction between annexin A2 and keratin 17: evidence for reciprocal regulation. J Biol Chem (2012) 0.84
Keratin intracellular concentration revisited: implications for keratin function in surface epithelia. J Invest Dermatol (2012) 0.82
Modeling the self-organization property of keratin intermediate filaments. Biophys J (2010) 0.81
Mouse models of alopecia: identifying structural genes that are baldly needed. Trends Mol Med (2003) 0.80
Preview. SKPing a hurdle: Sox2 and adult dermal stem cells. Cell Stem Cell (2009) 0.79
A new fold on an old story: attachment of intermediate filaments to desmosomes. Nat Struct Biol (2002) 0.79
Stressing the role of O-GlcNAc: linking cell survival to keratin modification. Nat Cell Biol (2010) 0.79
Oxidative stress and dysfunctional NRF2 underlie pachyonychia congenita phenotypes. J Clin Invest (2016) 0.78
Keratins and protein synthesis: the plot thickens. J Cell Biol (2009) 0.78
Mathematical modeling of the impact of actin and keratin filaments on keratinocyte cell spreading. Biophys J (2012) 0.77
Keratin intermediate filament proteins - novel regulators of inflammation and immunity in skin. J Cell Sci (2012) 0.76