Published in J Invest Dermatol on December 14, 2006
The human keratins: biology and pathology. Histochem Cell Biol (2008) 5.13
Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell (2009) 3.44
G-protein-coupled receptor GPR49 is up-regulated in basal cell carcinoma and promotes cell proliferation and tumor formation. Am J Pathol (2008) 1.60
The chicken frizzle feather is due to an α-keratin (KRT75) mutation that causes a defective rachis. PLoS Genet (2012) 1.36
Hedgehog signaling, keratin 6 induction, and sebaceous gland morphogenesis: implications for pachyonychia congenita and related conditions. Am J Pathol (2008) 0.95
Comparative anatomy of mouse and human nail units. Anat Rec (Hoboken) (2013) 0.91
Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development (2013) 0.87
Sam68/KHDRBS1-dependent NF-κB activation confers radioprotection to the colon epithelium in γ-irradiated mice. Elife (2016) 0.75
Histology and ultrastructure of transitional changes in skin morphology in the juvenile and adult four-striped mouse (Rhabdomys pumilio). ScientificWorldJournal (2013) 0.75
Proteomic Profiling of Hematopoietic Stem/Progenitor Cells after a Whole Body Exposure of CBA/CaJ Mice to Titanium ((48)Ti) Ions. Proteomes (2015) 0.75
A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. Nature (2006) 3.28
New consensus nomenclature for mammalian keratins. J Cell Biol (2006) 3.27
Contribution of olfactory neural stem cells to tissue maintenance and regeneration. Nat Neurosci (2007) 3.12
Intermediate filament proteins and their associated diseases. N Engl J Med (2004) 2.84
MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription. Genes Dev (2004) 2.07
Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm. Genes Dev (2007) 2.02
Keratin 16-null mice develop palmoplantar keratoderma, a hallmark feature of pachyonychia congenita and related disorders. J Invest Dermatol (2012) 1.72
Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin. Nat Genet (2010) 1.63
Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair. J Cell Biol (2003) 1.58
Overexpressed transient receptor potential vanilloid 3 ion channels in skin keratinocytes modulate pain sensitivity via prostaglandin E2. J Neurosci (2008) 1.53
Keratin 17 null mice exhibit age- and strain-dependent alopecia. Genes Dev (2002) 1.47
Hairless triggers reactivation of hair growth by promoting Wnt signaling. Proc Natl Acad Sci U S A (2005) 1.41
The expanding significance of keratin intermediate filaments in normal and diseased epithelia. Curr Opin Cell Biol (2012) 1.36
Emerging role for the cytoskeleton as an organizer and regulator of translation. Nat Rev Mol Cell Biol (2010) 1.35
Keratin function in skin epithelia: a broadening palette with surprising shades. Curr Opin Cell Biol (2006) 1.34
Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex. Proc Natl Acad Sci U S A (2007) 1.34
Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion. Genes Dev (2006) 1.26
The co-repressor hairless has a role in epithelial cell differentiation in the skin. Development (2004) 1.24
Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle. J Invest Dermatol (2002) 1.19
Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments. Mol Biol Cell (2002) 1.17
Keratin 16 regulates innate immunity in response to epidermal barrier breach. Proc Natl Acad Sci U S A (2013) 1.16
Exploiting the keratin 17 gene promoter to visualize live cells in epithelial appendages of mice. Mol Cell Biol (2005) 1.14
Self-organization of keratin intermediate filaments into cross-linked networks. J Cell Biol (2009) 1.12
The mechanical properties of simple epithelial keratins 8 and 18: discriminating between interfacial and bulk elasticities. J Struct Biol (2003) 1.11
Type II epithelial keratin 6hf (K6hf) is expressed in the companion layer, matrix, and medulla in anagen-stage hair follicles. J Invest Dermatol (2003) 1.11
An ex vivo assay to assess the potential of skin keratinocytes for wound epithelialization. J Invest Dermatol (2002) 1.11
Interaction between the keratin cytoskeleton and eEF1Bgamma affects protein synthesis in epithelial cells. Nat Struct Mol Biol (2007) 1.11
Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. Nat Struct Mol Biol (2012) 1.10
Differential modulation of keratin expression by sulforaphane occurs via Nrf2-dependent and -independent pathways in skin epithelia. Mol Biol Cell (2010) 1.10
A small surface hydrophobic stripe in the coiled-coil domain of type I keratins mediates tetramer stability. J Cell Biol (2005) 1.09
Networking galore: intermediate filaments and cell migration. Curr Opin Cell Biol (2013) 1.07
Role for keratins 6 and 17 during wound closure in embryonic mouse skin. Dev Dyn (2003) 1.07
Intermediate filaments and tissue repair. Exp Cell Res (2004) 1.04
A wound-induced keratin inhibits Src activity during keratinocyte migration and tissue repair. J Cell Biol (2012) 1.01
A novel mouse type I intermediate filament gene, keratin 17n (K17n), exhibits preferred expression in nail tissue. J Invest Dermatol (2004) 1.00
Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice. Mol Cell Biol (2005) 0.99
Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile. FASEB J (2007) 0.96
Hedgehog signaling, keratin 6 induction, and sebaceous gland morphogenesis: implications for pachyonychia congenita and related conditions. Am J Pathol (2008) 0.95
Barrier function in transgenic mice overexpressing K16, involucrin, and filaggrin in the suprabasal epidermis. J Invest Dermatol (2004) 0.92
Periderm prevents pathological epithelial adhesions during embryogenesis. J Clin Invest (2014) 0.91
Skin: an ideal model system to study keratin genes and proteins. Methods Cell Biol (2004) 0.89
Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion. J Biol Chem (2011) 0.87
Defining the properties of the nonhelical tail domain in type II keratin 5: insight from a bullous disease-causing mutation. Mol Biol Cell (2005) 0.86
Identification of novel interaction between annexin A2 and keratin 17: evidence for reciprocal regulation. J Biol Chem (2012) 0.84
Keratin intracellular concentration revisited: implications for keratin function in surface epithelia. J Invest Dermatol (2012) 0.82
Modeling the self-organization property of keratin intermediate filaments. Biophys J (2010) 0.81
Mouse models of alopecia: identifying structural genes that are baldly needed. Trends Mol Med (2003) 0.80
Preview. SKPing a hurdle: Sox2 and adult dermal stem cells. Cell Stem Cell (2009) 0.79
A new fold on an old story: attachment of intermediate filaments to desmosomes. Nat Struct Biol (2002) 0.79
Stressing the role of O-GlcNAc: linking cell survival to keratin modification. Nat Cell Biol (2010) 0.79
Oxidative stress and dysfunctional NRF2 underlie pachyonychia congenita phenotypes. J Clin Invest (2016) 0.78
Keratins and protein synthesis: the plot thickens. J Cell Biol (2009) 0.78
Mathematical modeling of the impact of actin and keratin filaments on keratinocyte cell spreading. Biophys J (2012) 0.77
Keratin intermediate filament proteins - novel regulators of inflammation and immunity in skin. J Cell Sci (2012) 0.76