Published in EMBO J on July 29, 2004
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Taking cell-matrix adhesions to the third dimension. Science (2001) 15.21
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PTEN and p53: who will get the upper hand? Cancer Cell (2003) 1.84
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The structure and function of PKN, a protein kinase having a catalytic domain homologous to that of PKC. J Biochem (2003) 1.51
Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor. Proc Natl Acad Sci U S A (2001) 1.49
Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA. Nucleic Acids Res (2003) 1.47
Phosphatidylinositol 3-kinases in tumor progression. Eur J Biochem (2001) 1.38
Inducible shRNA expression for application in a prostate cancer mouse model. Nucleic Acids Res (2003) 1.35
Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase. J Biol Chem (2000) 1.33
A novel inducible transactivation domain in the androgen receptor: implications for PRK in prostate cancer. EMBO J (2003) 1.32
To create the correct microenvironment: three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia. Methods (2003) 1.19
Dedifferentiation of adenocarcinomas by activation of phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A (1999) 1.03
GeneBlocs are powerful tools to study and delineate signal transduction processes that regulate cell growth and transformation. Antisense Nucleic Acid Drug Dev (2002) 0.99
Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha. Biochem Biophys Res Commun (1999) 0.93
Identification of novel effectors of invasive cell growth downstream of phosphoinositide 3-kinase. Biochem Soc Trans (2004) 0.77
Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis. J Cell Biol (2002) 5.01
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res (2003) 3.39
Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.). Br J Haematol (2013) 2.33
Lung-targeted RNA interference against angiopoietin-2 ameliorates multiple organ dysfunction and death in sepsis. Crit Care Med (2014) 1.83
Targeting cancer cells: magnetic nanoparticles as drug carriers. Eur Biophys J (2006) 1.52
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase. Oncogene (2005) 1.49
Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA. Nucleic Acids Res (2003) 1.47
Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4. Oncogene (2003) 1.46
Drug Repurposing Screen Identifies Foxo1-Dependent Angiopoietin-2 Regulation in Sepsis. Crit Care Med (2015) 1.45
The mitochondrial protein MTP18 contributes to mitochondrial fission in mammalian cells. J Cell Sci (2005) 1.44
Differential expression of the Drosophila mitofusin genes fuzzy onions (fzo) and dmfn. Mech Dev (2002) 1.36
Inducible shRNA expression for application in a prostate cancer mouse model. Nucleic Acids Res (2003) 1.35
Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression. Cancer Res (2008) 1.34
Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling. J Cell Mol Med (2008) 1.33
Round window stimulation with an implantable hearing aid (Soundbridge) combined with autogenous reconstruction of the auricle - a new approach. ORL J Otorhinolaryngol Relat Spec (2006) 1.29
Identifying prostate carcinoma by MALDI-Imaging. Int J Mol Med (2007) 1.27
Tumor suppressor activity of profilin requires a functional actin binding site. Mol Biol Cell (2004) 1.23
Diagnostic and prognostic information in prostate cancer with the help of a small set of hypermethylated gene loci. Clin Cancer Res (2005) 1.22
Sphingosine-1-phosphate modulates spiral modiolar artery tone: A potential role in vascular-based inner ear pathologies? Cardiovasc Res (2006) 1.21
TRB3 is a PI 3-kinase dependent indicator for nutrient starvation. Cell Signal (2005) 1.20
Deep electrode insertion in cochlear implants: apical morphology, electrodes and speech perception results. Acta Otolaryngol (2003) 1.19
ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2. Oncogene (2004) 1.19
Veria Operation. II. Surgical results from 101 cases. ORL J Otorhinolaryngol Relat Spec (2002) 1.14
Peroxiredoxin 6 is required for blood vessel integrity in wounded skin. J Cell Biol (2007) 1.12
Loss of Drp1 function alters OPA1 processing and changes mitochondrial membrane organization. Exp Cell Res (2009) 1.12
The human trithorax protein hASH2 functions as an oncoprotein. Cancer Res (2008) 1.08
Genetic and pharmacological inhibition of PDK1 in cancer cells: characterization of a selective allosteric kinase inhibitor. J Biol Chem (2010) 1.03
Phase I clinical development of Atu027, a siRNA formulation targeting PKN3 in patients with advanced solid tumors. Int J Clin Pharmacol Ther (2012) 1.02
Knockdown of MTP18, a novel phosphatidylinositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosis. J Biol Chem (2004) 1.00
Tumour-stroma interactions between metastatic prostate cancer cells and fibroblasts. Int J Mol Med (2006) 1.00
Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice. Mol Cell Neurosci (2007) 0.99
GeneBlocs are powerful tools to study and delineate signal transduction processes that regulate cell growth and transformation. Antisense Nucleic Acid Drug Dev (2002) 0.99
Adrenomedullin attenuates ventilator-induced lung injury in mice. Thorax (2010) 0.97
Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways. BMC Cancer (2011) 0.97
Multicenter randomized controlled trial comparing the performance of 22 gauge versus 25 gauge EUS-FNA needles in solid masses. Scand J Gastroenterol (2013) 0.96
Cellular retinoic acid-binding protein 2 is down-regulated in prostate cancer. Int J Oncol (2005) 0.95
Auditory nerve fibre responses to salicylate revisited. Hear Res (2003) 0.95
Atu027 prevents pulmonary metastasis in experimental and spontaneous mouse metastasis models. Clin Cancer Res (2010) 0.94
The interaction of PKN3 with RhoC promotes malignant growth. Mol Oncol (2011) 0.93
Regulation of epidermal homeostasis and repair by phosphoinositide 3-kinase. J Cell Sci (2006) 0.93
Characterization of {gamma}-aminobutyric acid type A receptor-associated protein, a novel tumor suppressor, showing reduced expression in breast cancer. Cancer Res (2005) 0.92
Genetic background of different cancer cell lines influences the gene set involved in chromosome 8 mediated breast tumor suppression. Genes Chromosomes Cancer (2006) 0.92
Mutational analysis of the BRAF, RAS and EGFR genes in human adrenocortical carcinomas. Endocr Relat Cancer (2009) 0.92
Veria operation updated. I. The trans-canal wall cochlear implantation. ORL J Otorhinolaryngol Relat Spec (2002) 0.92
Representation of acoustic signals in the human cochlea in presence of a cochlear implant electrode. Hear Res (2006) 0.91
A new translational repression element and unusual transcriptional control regulate expression of don juan during Drosophila spermatogenesis. Mech Dev (2002) 0.90
Mice transgenic for NPM-ALK develop non-Hodgkin lymphomas. Anticancer Res (2005) 0.90
Isoform-specific interaction of C-RAF with mitochondria. J Biol Chem (2008) 0.89
The MuSIC perception test: a novel battery for testing music perception of cochlear implant users. Cochlear Implants Int (2011) 0.88
ProteinChip Array analysis of microdissected colorectal carcinoma and associated tumor stroma shows specific protein bands in the 3.4 to 3.6 kDa range. Anticancer Res (2004) 0.88
Smad3 is a key nonredundant mediator of transforming growth factor beta signaling in Nme mouse mammary epithelial cells. Mol Cancer Res (2009) 0.87
Intracellular localization of lipoplexed siRNA in vascular endothelial cells of different mouse tissues. Microvasc Res (2008) 0.87
Priming with a combination of proangiogenic growth factors improves wound healing in normoglycemic mice. Int J Mol Med (2011) 0.86
Canalolithiasis of the superior semicircular canal: an anomaly in benign paroxysmal vertigo. Acta Otolaryngol (2005) 0.85
Noncontact laser catapulting: a basic procedure for functional genomics and proteomics. Methods Enzymol (2002) 0.85
Vertigo and cranial nerve palsy caused by different forms of spontaneous dissections of internal and vertebral arteries. Eur Arch Otorhinolaryngol (2002) 0.84
Stromal expression of invasion-promoting, matrix-degrading proteases MMP-1 and -9 and the Ets 1 transcription factor in HNPCC carcinomas and sporadic colorectal cancers. Int J Cancer (2003) 0.84
Radiology quiz case 1. Aberrant internal carotid artery (ICA) of the right middle ear. Arch Otolaryngol Head Neck Surg (2004) 0.84
Effects of mood stabilizers on the inhibition of adenylate cyclase via dopamine D(2)-like receptors. Bipolar Disord (2007) 0.83
Spontaneous epileptic rats show changes in sleep architecture and hypothalamic pathology. Epilepsia (2005) 0.82
Centrosome abnormalities in head and neck squamous cell carcinoma (HNSCC). Acta Otolaryngol (2009) 0.82