PubRank

Paul B Yu

Author PubWeight™ 35.65‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat Med 2008 4.20
2 Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors. Bioorg Med Chem Lett 2008 2.51
3 Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells. PLoS One 2008 1.99
4 Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva. J Biol Chem 2008 1.88
5 BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia. Am J Physiol Lung Cell Mol Physiol 2004 1.64
6 Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation. Blood 2011 1.61
7 Transforming Growth Factor {beta} Can Stimulate Smad1 Phosphorylation Independently of Bone Morphogenic Protein Receptors. J Biol Chem 2009 1.59
8 Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts. J Bone Miner Res 2010 1.54
9 Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice. Blood 2011 1.49
10 Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis. Arterioscler Thromb Vasc Biol 2012 1.46
11 Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4. J Biol Chem 2007 1.45
12 A new class of small molecule inhibitor of BMP signaling. PLoS One 2013 1.36
13 Applications of small molecule BMP inhibitors in physiology and disease. Cytokine Growth Factor Rev 2009 1.35
14 p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7. J Biol Chem 2009 1.04
15 Augmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice. J Bone Miner Res 2013 1.01
16 Development of an ALK2-biased BMP type I receptor kinase inhibitor. ACS Chem Biol 2013 0.99
17 Takotsubo cardiomyopathy complicated by cardiac tamponade: classic hemodynamic findings with a new disease. Circulation 2010 0.97
18 Constitutively active ALK2 receptor mutants require type II receptor cooperation. Mol Cell Biol 2013 0.96
19 ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells. Cancer Res 2012 0.94
20 Images in cardiovascular medicine. Left atrial-esophageal fistula after pulmonary vein isolation: a cautionary tale. Circulation 2007 0.92
21 Hepcidin regulation by BMP signaling in macrophages is lipopolysaccharide dependent. PLoS One 2012 0.91
22 The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6. Blood 2014 0.91
23 Circulating angiogenic modulatory factors predict survival and functional class in pulmonary arterial hypertension. Pulm Circ 2013 0.84
24 Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants. J Med Chem 2014 0.78
25 Excess placental secreted frizzled-related protein 1 in maternal smokers impairs fetal growth. J Clin Invest 2015 0.76
26 Brief Report: Coordinated Modulation of Circulating miR-21 in HIV, HIV-Associated Pulmonary Arterial Hypertension, and HIV/Hepatitis C Virus Coinfection. J Acquir Immune Defic Syndr 2015 0.76
27 Elafin in pulmonary arterial hypertension. Beyond targeting elastases. Am J Respir Crit Care Med 2015 0.75