CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates.

PubWeight™: 2.45‹?› | Rank: Top 2%

🔗 View Article (PMID 15307826)

Published in Am J Transplant on September 01, 2004

Authors

Tatsuo Kawai1, Hiroshi Sogawa, Svetlan Boskovic, Gregory Abrahamian, Rex-Neal Smith, Siew-Lin Wee, David Andrews, Ognjenka Nadazdin, Ichiro Koyama, Megan Sykes, Henry J Winn, Robert B Colvin, David H Sachs, A Benedict Cosimi

Author Affiliations

1: Department of Surgery, Transplantation Unit, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA. tkawai@partners.org

Articles citing this

HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med (2008) 7.42

Host alloreactive memory T cells influence tolerance to kidney allografts in nonhuman primates. Sci Transl Med (2011) 1.97

Depletion of CD8 memory T cells for induction of tolerance of a previously transplanted kidney allograft. Am J Transplant (2007) 1.64

Evidence for kidney rejection after combined bone marrow and renal transplantation despite ongoing whole-blood chimerism in rhesus macaques. Am J Transplant (2012) 1.54

Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression. Am J Transplant (2014) 1.49

Use of CTLA4Ig for induction of mixed chimerism and renal allograft tolerance in nonhuman primates. Am J Transplant (2014) 1.44

Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts. Am J Transplant (2011) 1.38

HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med (2013) 1.29

Overcoming memory T-cell responses for induction of delayed tolerance in nonhuman primates. Am J Transplant (2011) 1.20

Transplantation tolerance through mixed chimerism. Nat Rev Nephrol (2010) 1.17

An MHC-defined primate model reveals significant rejection of bone marrow after mixed chimerism induction despite full MHC matching. Am J Transplant (2010) 1.13

Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism. Curr Opin Organ Transplant (2011) 1.10

Induction of transplantation tolerance in non-human primate preclinical models. Philos Trans R Soc Lond B Biol Sci (2005) 1.02

Comparison of lung and kidney allografts in induction of tolerance by a mixed-chimerism approach in cynomolgus monkeys. Transplant Proc (2009) 0.98

Induction of tolerance through mixed chimerism. Cold Spring Harb Perspect Med (2014) 0.97

Preserving the B-cell compartment favors operational tolerance in human renal transplantation. Mol Med (2012) 0.97

Renal and cardiac endothelial heterogeneity impact acute vascular rejection in pig-to-baboon xenotransplantation. Am J Transplant (2009) 0.93

Costimulatory pathways in transplantation. Semin Immunol (2011) 0.90

Heterogeneity within T Cell Memory: Implications for Transplant Tolerance. Front Immunol (2012) 0.89

Hematopoietic cell transplantation for tolerance induction: animal models to clinical trials. Transplantation (2009) 0.89

Tolerogenic therapies in transplantation. Front Immunol (2012) 0.88

Tolerance of Lung Allografts Achieved in Nonhuman Primates via Mixed Hematopoietic Chimerism. Am J Transplant (2015) 0.88

Therapeutic issues in the treatment of vascularized xenotransplants using gal-knockout donors in nonhuman primates. Curr Opin Organ Transplant (2011) 0.88

Development of tolerogenic strategies in the clinic. Philos Trans R Soc Lond B Biol Sci (2005) 0.86

Mixed chimerism to induce tolerance: lessons learned from nonhuman primates. Transplant Rev (Orlando) (2009) 0.85

Chimerism-based tolerance in organ transplantation: preclinical and clinical studies. Clin Exp Immunol (2017) 0.84

Manipulating the immune system for anti-tumor responses and transplant tolerance via mixed hematopoietic chimerism. Immunol Rev (2008) 0.83

Contributions of direct and indirect alloresponses to chronic rejection of kidney allografts in nonhuman primates. J Immunol (2011) 0.83

Challenges in the pursuit of immune tolerance. Immunol Rev (2011) 0.83

Hematopoietic chimerism and transplantation tolerance: a role for regulatory T cells. Front Immunol (2011) 0.83

Transgenic expression of human CD47 markedly increases engraftment in a murine model of pig-to-human hematopoietic cell transplantation. Am J Transplant (2014) 0.82

Repeated Injections of IL-2 Break Renal Allograft Tolerance Induced via Mixed Hematopoietic Chimerism in Monkeys. Am J Transplant (2015) 0.82

Immunogenetic Management Software: a new tool for visualization and analysis of complex immunogenetic datasets. Immunogenetics (2011) 0.82

Alefacept promotes immunosuppression-free renal allograft survival in nonhuman primates via depletion of recipient memory T cells. Am J Transplant (2013) 0.81

Development and in vitro characterization of canine CD40-Ig. Vet Immunol Immunopathol (2008) 0.81

What's new in clinical solid organ transplantation by 2013. World J Transplant (2014) 0.81

Stem cell mobilization and collection for induction of mixed chimerism and renal allograft tolerance in cynomolgus monkeys. J Surg Res (2010) 0.80

Hematopoietic stem cell infusion/transplantation for induction of allograft tolerance. Curr Opin Organ Transplant (2015) 0.80

Transplant tolerance: new insights and strategies for long-term allograft acceptance. Clin Dev Immunol (2013) 0.80

Effect of ex vivo Expanded Recipient Regulatory T Cells on Hematopoietic Chimerism and Kidney Allograft Tolerance Across MHC Barriers in Cynomolgus Macaques. Transplantation (2016) 0.80

Transplantation tolerance: Clinical potential of regulatory T cells. Self Nonself (2011) 0.79

Depletion of foxp3(+) T cells abrogates tolerance of skin and heart allografts in murine mixed chimeras without the loss of mixed chimerism. Am J Transplant (2014) 0.79

Heart transplantation: challenges facing the field. Cold Spring Harb Perspect Med (2014) 0.79

Co-expression of sCD40LIg and CTLA4Ig mediated by adenovirus prolonged mouse skin allograft survival. J Zhejiang Univ Sci B (2006) 0.79

Dipeptidyl peptidase IV (DPPIV/CD26) inhibition does not improve engraftment of unfractionated syngeneic or allogeneic bone marrow after nonmyeloablative conditioning. Exp Hematol (2011) 0.78

Lymphodepletional strategies in transplantation. Cold Spring Harb Perspect Med (2013) 0.78

Tolerance induction after organ transplantation, "delayed tolerance," via the mixed chimerism approach: planting flowers in a battle field. Chimerism (2012) 0.78

Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy. Immunol Rev (2017) 0.78

Immunosuppression for in vivo research: state-of-the-art protocols and experimental approaches. Cell Mol Immunol (2016) 0.77

Use of hematopoietic cell transplants to achieve tolerance in patients with solid organ transplants. Blood (2016) 0.77

Kidney Versus Islet Allograft Survival After Induction of Mixed Chimerism With Combined Donor Bone Marrow Transplantation. Cell Transplant (2015) 0.77

Primate models in organ transplantation. Cold Spring Harb Perspect Med (2013) 0.77

Transplant tolerance: bench to bedside--26th annual Samuel Jason Mixter Lecture. Arch Surg (2011) 0.76

Induction of tolerance in clinical kidney transplantation. Clin Transplant (2010) 0.76

Alloreactive Regulatory T Cells Allow the Generation of Mixed Chimerism and Transplant Tolerance. Front Immunol (2015) 0.76

Transplantation Tolerance Induction: Cell Therapies and Their Mechanisms. Front Immunol (2016) 0.76

Limited efficacy and unacceptable toxicity of cyclophosphamide for the induction of mixed chimerism and renal allograft tolerance in cynomolgus monkeys. Transplantation (2008) 0.76

Organ-specific differences in achieving tolerance. Curr Opin Organ Transplant (2015) 0.76

Recombinant anti-monkey CD3 immunotoxin depletes peripheral lymph node T lymphocytes more effectively than rabbit anti-thymocyte globulin in naïve baboons. Transpl Immunol (2013) 0.76

Prolonged Survival of Pig Skin on Baboons After Administration of Pig Cells Expressing Human CD47. Transplantation (2016) 0.75

Old game, new players: Linking classical theories to new trends in transplant immunology. World J Transplant (2017) 0.75

Role of Memory T Cells in Allograft Rejection and Tolerance. Front Immunol (2017) 0.75

Fc-Silent Anti-CD154 Domain Antibody Effectively Prevents Non-Human Primate Renal Allograft Rejection. Am J Transplant (2017) 0.75

Induced regulatory T cells in allograft tolerance via transient mixed chimerism. JCI Insight (2016) 0.75

The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques. Am J Transplant (2016) 0.75

Donor-specific tolerance induction in organ transplantation via mixed splenocytes chimerism. Clin Exp Immunol (2013) 0.75

Chronic Antibody-Mediated Rejection in Nonhuman Primate Renal Allografts: Validation of Human Histological and Molecular Phenotypes. Am J Transplant (2017) 0.75

Novel H-shunt Venovenous Bypass for Liver Transplantation in Cynomolgus Macaques. Comp Med (2017) 0.75

Articles by these authors

HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med (2008) 7.42

Strategies to improve long-term outcomes after renal transplantation. N Engl J Med (2002) 6.76

Antibody-mediated rejection criteria - an addition to the Banff 97 classification of renal allograft rejection. Am J Transplant (2003) 4.54

Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue. Nat Med (2004) 3.63

Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med (2004) 3.58

Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets. Immunity (2012) 3.21

Campath-1H induction plus rapamycin monotherapy for renal transplantation: results of a pilot study. Am J Transplant (2003) 2.83

Case records of the Massachusetts General Hospital. Case 31-2007. A 41-year-old man with abdominal pain and elevated serum creatinine. N Engl J Med (2007) 2.71

Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice. J Virol (2009) 2.70

Case records of the Massachusetts General Hospital. Case 23-2010. A 49-year-old man with erythrocytosis, perinephric fluid collections, and renal failure. N Engl J Med (2010) 2.62

Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation. Transplantation (2013) 2.55

Production of alpha-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations. Proc Natl Acad Sci U S A (2004) 2.54

Public stem cell banks: considerations of justice in stem cell research and therapy. Hastings Cent Rep (2004) 2.53

Clinical trial of islet xenotransplantation in Mexico. Xenotransplantation (2006) 2.51

In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature (2011) 2.44

Morphometric and visual evaluation of fibrosis in renal biopsies. J Am Soc Nephrol (2010) 2.32

Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations. Arch Pathol Lab Med (2009) 2.30

Organ transplantation--how much of the promise has been realized? Nat Med (2005) 2.26

Globotriaosylceramide accumulation in the Fabry kidney is cleared from multiple cell types after enzyme replacement therapy. Kidney Int (2002) 2.15

Pros and cons for C4d as a biomarker. Kidney Int (2012) 2.03

National conference to assess antibody-mediated rejection in solid organ transplantation. Am J Transplant (2004) 2.01

Melanoma patients with positive sentinel nodes who did not undergo completion lymphadenectomy: a multi-institutional study. Ann Surg Oncol (2006) 2.00

Host alloreactive memory T cells influence tolerance to kidney allografts in nonhuman primates. Sci Transl Med (2011) 1.97

Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. Proc Natl Acad Sci U S A (2009) 1.95

An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues. J Exp Med (2006) 1.94

Diagnosis of IgG4-related tubulointerstitial nephritis. J Am Soc Nephrol (2011) 1.92

Tolerance induction in clinical transplantation. Transpl Immunol (2004) 1.90

Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance. J Clin Oncol (2004) 1.87

Acute humoral rejection in kidney transplantation: II. Morphology, immunopathology, and pathologic classification. J Am Soc Nephrol (2002) 1.84

Thrombophilia associated with anti-CD154 monoclonal antibody treatment and its prophylaxis in nonhuman primates. Transplantation (2004) 1.82

The 5-year outcome of ABO-incompatible kidney transplantation with rituximab induction. Transplantation (2011) 1.82

Xenotransplantation: current status and a perspective on the future. Nat Rev Immunol (2007) 1.80

Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages. Proc Natl Acad Sci U S A (2007) 1.80

Thrombotic microangiopathic glomerulopathy in human decay accelerating factor-transgenic swine-to-baboon kidney xenografts. J Am Soc Nephrol (2005) 1.79

A pathophysiologic role for T lymphocytes in murine acute cisplatin nephrotoxicity. J Am Soc Nephrol (2006) 1.77

Induction of kidney allograft tolerance after transient lymphohematopoietic chimerism in patients with multiple myeloma and end-stage renal disease. Transplantation (2002) 1.75

Will the pig solve the transplantation backlog? Annu Rev Med (2002) 1.74

Overlapping pathways to transplant glomerulopathy: chronic humoral rejection, hepatitis C infection, and thrombotic microangiopathy. Kidney Int (2011) 1.73

Prevalence of renal cell carcinoma in patients with ESRD pre-transplantation: a pathologic analysis. Kidney Int (2002) 1.72

Biology of desmoplastic melanoma: a case-control comparison with other melanomas. J Clin Oncol (2005) 1.71

Development of focal segmental glomerulosclerosis after anabolic steroid abuse. J Am Soc Nephrol (2009) 1.70

Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells. Blood (2002) 1.68

Low-temperature extremophiles and their applications. Curr Opin Biotechnol (2002) 1.65

Local irradiation enhances congenic donor pluripotent hematopoietic stem cell engraftment similarly in irradiated and nonirradiated sites. Blood (2003) 1.64

Autoimmune pancreatitis: a systemic immune complex mediated disease. Am J Surg Pathol (2006) 1.62

Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model. Blood (2008) 1.60

Long-term survival, nutritional autonomy, and quality of life after intestinal and multivisceral transplantation. Ann Surg (2012) 1.59

Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry. EMBO J (2003) 1.59

NK cells can trigger allograft vasculopathy: the role of hybrid resistance in solid organ allografts. J Immunol (2005) 1.58

alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months. Transplantation (2005) 1.56

Liver transplantation for malignancy. Oncologist (2005) 1.54

Pseudotumors due to IgG4 immune-complex tubulointerstitial nephritis associated with autoimmune pancreatocentric disease. Am J Surg Pathol (2007) 1.53

Prospective study of liver transplant recipients with HCV infection: evidence for a causal relationship between HCV and insulin resistance. Liver Transpl (2008) 1.50

Phenotypic and functional characterization of kidney-infiltrating lymphocytes in renal ischemia reperfusion injury. J Immunol (2006) 1.50

The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade. Blood (2002) 1.49

The beneficial impact of temporary porto-caval shunt in orthotopic liver transplantation: a single center analysis. Transpl Int (2010) 1.48

Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 36-2003. A 68-year-old woman with impaired renal function. N Engl J Med (2003) 1.47

Xenogeneic thymus transplantation in a pig-to-baboon model. Transplantation (2003) 1.47

Renal interstitial fibrosis: mechanisms and evaluation. Curr Opin Nephrol Hypertens (2012) 1.46

Clinical role of the renal transplant biopsy. Nat Rev Nephrol (2012) 1.46

Kidney transplantation: mechanisms of rejection and acceptance. Annu Rev Pathol (2008) 1.46

The transesophageal echo probe may contribute to esophageal injury after catheter ablation for paroxysmal atrial fibrillation under general anesthesia: a preliminary observation. J Cardiovasc Electrophysiol (2014) 1.44

Attenuation of phagocytosis of xenogeneic cells by manipulating CD47. Blood (2006) 1.44

Pathology after eculizumab in dense deposit disease and C3 GN. J Am Soc Nephrol (2012) 1.43

Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy. PLoS One (2007) 1.42

Immunogenicity of umbilical cord tissue derived cells. Blood (2007) 1.42

A prospective, randomized clinical trial of cyclosporine reduction in stable patients greater than 12 months after renal transplantation. Transplantation (2003) 1.41

A mouse B-cell alloantigen determined by gene(s) linked to the major histocompatibility complex. The Journal of Experimental Medicine. 1973. 138: 1289-1304. J Immunol (2011) 1.39

Penis Transplantation: First US Experience. Ann Surg (2017) 1.38

The role of antigen-presenting cells in triggering graft-versus-host disease and graft-versus-leukemia. Blood (2007) 1.37

Nonmyeloablative haploidentical stem-cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies. Transplantation (2003) 1.36

Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons. Am J Pathol (2008) 1.36

Identification of exogenous forms of human-tropic porcine endogenous retrovirus in miniature Swine. J Virol (2004) 1.35

Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation. Biol Blood Marrow Transplant (2003) 1.35

Peritoneal cavity B cells are precursors of splenic IgM natural antibody-producing cells. J Immunol (2003) 1.34

Histocompatible miniature swine: an inbred large-animal model. Transplantation (2003) 1.33