Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity.

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The development of inducible bronchus-associated lymphoid tissue depends on IL-17. Nat Immunol (2011) 3.13

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Omental milky spots develop in the absence of lymphoid tissue-inducer cells and support B and T cell responses to peritoneal antigens. Immunity (2009) 2.68

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Inhibition of LTi cell development by CD25 blockade is associated with decreased intrathecal inflammation in multiple sclerosis. Sci Transl Med (2012) 2.14

Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus-infected mice. J Exp Med (2009) 2.12

Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice. J Exp Med (2009) 2.12

Induced bronchus-associated lymphoid tissue serves as a general priming site for T cells and is maintained by dendritic cells. J Exp Med (2009) 2.10

ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes. Proc Natl Acad Sci U S A (2008) 2.10

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Cutting edge: intravascular staining redefines lung CD8 T cell responses. J Immunol (2012) 1.99

Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung. Cancer Res (2010) 1.83

Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors. Immunity (2015) 1.74

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Ectopic lymphoid-like structures in infection, cancer and autoimmunity. Nat Rev Immunol (2014) 1.72

Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation. Nat Immunol (2009) 1.71

Salmonella Infection Drives Promiscuous B Cell Activation Followed by Extrafollicular Affinity Maturation. Immunity (2015) 1.70

IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs. J Exp Med (2014) 1.67

The immunopathogenesis of chronic obstructive pulmonary disease: insights from recent research. Proc Am Thorac Soc (2007) 1.65

Cutting edge: Acute lung allograft rejection is independent of secondary lymphoid organs. J Immunol (2009) 1.64

Lung niches for the generation and maintenance of tissue-resident memory T cells. Mucosal Immunol (2013) 1.62

How B cells shape the immune response against Mycobacterium tuberculosis. Eur J Immunol (2009) 1.61

Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity. PLoS Biol (2009) 1.60

Pulmonary expression of CXC chemokine ligand 13, CC chemokine ligand 19, and CC chemokine ligand 21 is essential for local immunity to influenza. Proc Natl Acad Sci U S A (2007) 1.56

CXCR5⁺ T helper cells mediate protective immunity against tuberculosis. J Clin Invest (2013) 1.55

Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cells. J Exp Med (2010) 1.51

Distinct germinal center selection at local sites shapes memory B cell response to viral escape. J Exp Med (2015) 1.50

Autoreactive T and B cells induce the development of bronchus-associated lymphoid tissue in the lung. Am J Respir Cell Mol Biol (2013) 1.49

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Efficient mucosal vaccination mediated by the neonatal Fc receptor. Nat Biotechnol (2011) 1.47

Human and murine obliterative bronchiolitis in transplant. Proc Am Thorac Soc (2007) 1.45

Vaccination against human influenza A/H3N2 virus prevents the induction of heterosubtypic immunity against lethal infection with avian influenza A/H5N1 virus. PLoS One (2009) 1.44

Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis. PLoS Pathog (2010) 1.43

Specific remodeling of splenic architecture by cytomegalovirus. PLoS Pathog (2006) 1.43

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection. Nat Immunol (2013) 1.37

Global transcriptome analysis in influenza-infected mouse lungs reveals the kinetics of innate and adaptive host immune responses. PLoS One (2012) 1.37

Characteristics of tertiary lymphoid structures in primary cancers. Oncoimmunology (2013) 1.35

Guarding the perimeter: protection of the mucosa by tissue-resident memory T cells. Mucosal Immunol (2012) 1.35

Recall responses by helpless memory CD8+ T cells are restricted by the up-regulation of PD-1. J Immunol (2009) 1.34

Protective B cell responses to flu--no fluke! J Immunol (2011) 1.28

Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells. Blood (2008) 1.27

CD8 T cell recall responses are regulated by the tissue tropism of the memory cell and pathogen. J Immunol (2006) 1.24

A systemic neutrophil response precedes robust CD8(+) T-cell activation during natural respiratory syncytial virus infection in infants. J Virol (2009) 1.24

Late signals from CD27 prevent Fas-dependent apoptosis of primary CD8+ T cells. J Immunol (2008) 1.24

Inducible bronchus-associated lymphoid tissue elicited by a protein cage nanoparticle enhances protection in mice against diverse respiratory viruses. PLoS One (2009) 1.23

The impact of successive infections on the lung microenvironment. Immunology (2007) 1.21

Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection. Proc Natl Acad Sci U S A (2012) 1.20

Ontogeny of stromal organizer cells during lymph node development. J Immunol (2010) 1.20

Evaluation of the presence of B-cell attractant chemokines in chronic rhinosinusitis. Am J Rhinol Allergy (2010) 1.14

The microbiology of asthma. Nat Rev Microbiol (2012) 1.14

Protection against genital herpes infection in mice immunized under different hormonal conditions correlates with induction of vagina-associated lymphoid tissue. J Virol (2005) 1.14

Emergency granulopoiesis promotes neutrophil-dendritic cell encounters that prevent mouse lung allograft acceptance. Blood (2011) 1.12

Respiratory infections: do we ever recover? Proc Am Thorac Soc (2007) 1.11

Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors. Proc Natl Acad Sci U S A (2012) 1.10

Broad dispersion and lung localization of virus-specific memory B cells induced by influenza pneumonia. Proc Natl Acad Sci U S A (2008) 1.10

The role of B cells and humoral immunity in Mycobacterium tuberculosis infection. Adv Exp Med Biol (2013) 1.09

Age-related sensitivity and pathological differences in infections by 2009 pandemic influenza A (H1N1) virus. Virol J (2011) 1.09

Early-life viral infection and allergen exposure interact to induce an asthmatic phenotype in mice. Respir Res (2010) 1.07

Lymphoid chemokines in the CNS. J Neuroimmunol (2010) 1.07

Immunobiology of chronic lung allograft dysfunction: new insights from the bench and beyond. Am J Transplant (2009) 1.07

A neonatal Fc receptor-targeted mucosal vaccine strategy effectively induces HIV-1 antigen-specific immunity to genital infection. J Virol (2011) 1.06

Dendritic cells produce CXCL13 and participate in the development of murine small intestine lymphoid tissues. Am J Pathol (2010) 1.06

Mucosal inoculation with an attenuated mouse pneumovirus strain protects against virulent challenge in wild type and interferon-gamma receptor deficient mice. Vaccine (2006) 1.06

Pulmonary infection with influenza A virus induces site-specific germinal center and T follicular helper cell responses. PLoS One (2012) 1.05

Lung dendritic cells at the innate-adaptive immune interface. J Leukoc Biol (2011) 1.03

Lung transplant acceptance is facilitated by early events in the graft and is associated with lymphoid neogenesis. Mucosal Immunol (2012) 1.02

Lack of a major role of Staphylococcus aureus Panton-Valentine leukocidin in lower respiratory tract infection in nonhuman primates. Am J Pathol (2010) 1.01

Suppression of innate immune pathology by regulatory T cells during Influenza A virus infection of immunodeficient mice. J Virol (2010) 1.01

Protective antiviral antibody responses in a mouse model of influenza virus infection require TACI. J Clin Invest (2011) 1.01

Virally delivered cytokines alter the immune response to future lung infections. J Virol (2007) 1.01

T cell responses during influenza infection: getting and keeping control. Trends Immunol (2011) 1.00

Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway. J Immunol (2011) 1.00

Pathogenesis of a model gammaherpesvirus in a natural host. J Virol (2010) 0.99

Central memory CD8+ T lymphocytes mediate lung allograft acceptance. J Clin Invest (2014) 0.99

Active uptake of dendritic cell-derived exovesicles by epithelial cells induces the release of inflammatory mediators through a TNF-alpha-mediated pathway. Am J Pathol (2009) 0.99

Aerosolized Ebola vaccine protects primates and elicits lung-resident T cell responses. J Clin Invest (2015) 0.99

The immune microenvironment of human tumors: general significance and clinical impact. Cancer Microenviron (2012) 0.98

The role of B cells and humoral immunity in Mycobacterium tuberculosis infection. Semin Immunol (2014) 0.98

Phenotypic alterations in type II alveolar epithelial cells in CD4+ T cell mediated lung inflammation. Respir Res (2007) 0.98

Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis. Nat Commun (2015) 0.97

The delivery site of a monovalent influenza vaccine within the respiratory tract impacts on the immune response. Immunology (2007) 0.96

Tertiary Lymphoid Structure-Associated B Cells are Key Players in Anti-Tumor Immunity. Front Immunol (2015) 0.96

Th17 cell based vaccines in mucosal immunity. Curr Opin Immunol (2013) 0.95

Prophylactic administration of bacterially derived immunomodulators improves the outcome of influenza virus infection in a murine model. J Virol (2010) 0.95

Dendritic cells and influenza A virus infection. Virulence (2012) 0.95

Harnessing local and systemic immunity for vaccines against tuberculosis. Mucosal Immunol (2013) 0.95

Interleukin-12 as an adjuvant for induction of protective antibody responses. Cytokine (2010) 0.94

Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells. Nat Commun (2016) 0.94

Nrf2 regulates chronic lung inflammation and B-cell responses to nontypeable Haemophilus influenzae. Am J Respir Cell Mol Biol (2011) 0.93

Off balance: T-cells in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides. Clin Exp Immunol (2005) 0.92

Differential pathological and immune responses in newly weaned ferrets are associated with a mild clinical outcome of pandemic 2009 H1N1 infection. J Virol (2012) 0.91

Every breath you take: the impact of environment on resident memory CD8 T cells in the lung. Front Immunol (2014) 0.90

IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol (2007) 10.71

Effector and regulatory B cells: modulators of CD4+ T cell immunity. Nat Rev Immunol (2010) 3.56

Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis. Immunity (2009) 3.33

Activated primary and memory CD8 T cells migrate to nonlymphoid tissues regardless of site of activation or tissue of origin. J Immunol (2004) 3.15

Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus. J Exp Med (2008) 3.15

The development of inducible bronchus-associated lymphoid tissue depends on IL-17. Nat Immunol (2011) 3.13

Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8+ T cells. J Exp Med (2007) 3.09

Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation. Immunity (2012) 2.87

Omental milky spots develop in the absence of lymphoid tissue-inducer cells and support B and T cell responses to peritoneal antigens. Immunity (2009) 2.68

Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis. J Clin Invest (2006) 2.56

Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection. J Exp Med (2006) 2.55

Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge. Immunity (2010) 2.52

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Cytokine-producing effector B cells regulate type 2 immunity to H. polygyrus. Immunity (2009) 2.45

Differential contributions of central and effector memory T cells to recall responses. J Exp Med (2005) 2.40

Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenza. Nat Immunol (2010) 2.27

Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responses. J Exp Med (2004) 2.23

Regulation of dendritic cell trafficking by the ADP-ribosyl cyclase CD38: impact on the development of humoral immunity. Immunity (2004) 2.23

Gamma-herpesvirus latency is preferentially maintained in splenic germinal center and memory B cells. J Exp Med (2002) 2.20

Ectopic lymphoid tissues and local immunity. Semin Immunol (2008) 2.18

Memory T cell populations in the lung airways are maintained by continual recruitment. J Immunol (2006) 2.17

Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide. J Neurosci (2009) 2.15

The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections. Immunity (2008) 2.13

A novel role for non-neutralizing antibodies against nucleoprotein in facilitating resistance to influenza virus. J Immunol (2008) 2.10

ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes. Proc Natl Acad Sci U S A (2008) 2.10

Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis. J Exp Med (2010) 2.10

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Differential antigen presentation regulates the changing patterns of CD8+ T cell immunodominance in primary and secondary influenza virus infections. J Exp Med (2003) 2.07

Nonspecific recruitment of memory CD8+ T cells to the lung airways during respiratory virus infections. J Immunol (2003) 2.01

Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo. J Immunol (2004) 2.00

Persistence and responsiveness of immunologic memory in the absence of secondary lymphoid organs. Immunity (2006) 1.95

T-cell memory and recall responses to respiratory virus infections. Immunol Rev (2006) 1.95

Cutting edge: effector memory CD8+ T cells play a prominent role in recall responses to secondary viral infection in the lung. J Immunol (2004) 1.90

CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly. Proc Natl Acad Sci U S A (2003) 1.89

B cells are required for generation of protective effector and memory CD4 cells in response to Pneumocystis lung infection. J Immunol (2006) 1.86

Distinct functions of antigen-specific CD4 T cells during murine Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A (2010) 1.85

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NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells. Am J Physiol Cell Physiol (2006) 1.82

Priming with cold-adapted influenza A does not prevent infection but elicits long-lived protection against supralethal challenge with heterosubtypic virus. J Immunol (2007) 1.78

CD4 T cell-independent antibody response promotes resolution of primary influenza infection and helps to prevent reinfection. J Immunol (2005) 1.77

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Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation. Nat Immunol (2009) 1.71

Newly generated CD4 T cells in aged animals do not exhibit age-related defects in response to antigen. J Exp Med (2005) 1.59

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CXCR5⁺ T helper cells mediate protective immunity against tuberculosis. J Clin Invest (2013) 1.55

CXCR3 directs antigen-specific effector CD4+ T cell migration to the lung during parainfluenza virus infection. J Immunol (2009) 1.53

Cutting edge: Antigen is not required for the activation and maintenance of virus-specific memory CD8+ T cells in the lung airways. J Immunol (2007) 1.46

IL-15 regulates both quantitative and qualitative features of the memory CD8 T cell pool. J Immunol (2009) 1.45

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The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: reciprocal regulation by interleukin (IL)-4 and IL-12. J Exp Med (2002) 1.40

Inflammatory chemokine receptors regulate CD8(+) T cell contraction and memory generation following infection. J Exp Med (2011) 1.40

IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung. J Immunol (2011) 1.40

Early dysregulation of the memory CD8+ T cell repertoire leads to compromised immune responses to secondary viral infection in the aged. Immun Ageing (2012) 1.39

In a murine tuberculosis model, the absence of homeostatic chemokines delays granuloma formation and protective immunity. J Immunol (2009) 1.38

Cutting edge: T-bet and IL-27R are critical for in vivo IFN-gamma production by CD8 T cells during infection. J Immunol (2008) 1.36

Profiling early lung immune responses in the mouse model of tuberculosis. PLoS One (2011) 1.36

B cells promote resistance to heterosubtypic strains of influenza via multiple mechanisms. J Immunol (2008) 1.35