Published in Infect Immun on September 01, 2004
Helicobacter pylori and gastric cancer: factors that modulate disease risk. Clin Microbiol Rev (2010) 3.41
Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion. J Exp Med (2005) 1.66
Helicobacter pylori dysregulation of gastric epithelial tight junctions by urease-mediated myosin II activation. Gastroenterology (2008) 1.41
Helicobacter pylori chemotaxis modulates inflammation and bacterium-gastric epithelium interactions in infected mice. Infect Immun (2007) 1.39
Role of Annexin-II in GI cancers: interaction with gastrins/progastrins. Cancer Lett (2006) 1.22
Helicobacter pylori in gastric carcinogenesis: mechanisms. Gastroenterol Clin North Am (2013) 1.11
IQGAP1 in microbial pathogenesis: Targeting the actin cytoskeleton. FEBS Lett (2011) 0.97
"Targeted disruption of the epithelial-barrier by Helicobacter pylori". Cell Commun Signal (2011) 0.92
Regulation of the actin cytoskeleton in Helicobacter pylori-induced migration and invasive growth of gastric epithelial cells. Cell Commun Signal (2011) 0.88
Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer. Carcinogenesis (2008) 0.85
Helicobacter pylori-induced alteration of epithelial cell signaling and polarity: a possible mechanism of gastric carcinoma etiology and disparity. Cytoskeleton (Hoboken) (2013) 0.84
Epistemology of the origin of cancer: a new paradigm. BMC Cancer (2014) 0.83
Helicobacter pylori activates calpain via toll-like receptor 2 to disrupt adherens junctions in human gastric epithelial cells. Infect Immun (2011) 0.83
Polymorphisms in the 3'-untranslated region of the CDH1 gene are a risk factor for primary gastric diffuse large B-cell lymphoma. Haematologica (2011) 0.81
Time-series gene expression profiles in AGS cells stimulated with Helicobacter pylori. World J Gastroenterol (2010) 0.79
Deletion of IQGAP1 promotes Helicobacter pylori-induced gastric dysplasia in mice and acquisition of cancer stem cell properties in vitro. Oncotarget (2016) 0.78
Helicobacter pylori impedes acid-induced tightening of gastric epithelial junctions. Am J Physiol Gastrointest Liver Physiol (2013) 0.78
Genomics, microRNA, epigenetics, and proteomics for future diagnosis, treatment and monitoring response in upper GI cancers. Clin Transl Med (2016) 0.77
New NCI-N87-derived human gastric epithelial line after human telomerase catalytic subunit over-expression. World J Gastroenterol (2015) 0.75
Alkannin inhibits growth and invasion of glioma cells C6 through IQGAP/mTOR signal pathway. Int J Clin Exp Med (2015) 0.75
The homing receptor CD44 is involved in the progression of precancerous gastric lesions in patients infected with Helicobacter pylori and in development of mucous metaplasia in mice. Cancer Lett (2015) 0.75
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell (1995) 24.99
cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci U S A (1996) 16.69
Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science (2003) 5.23
Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion. Science (1998) 3.39
Rho GTPases. J Biol Chem (1998) 3.35
Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior. J Cell Biol (2001) 3.28
Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. J Immunol (2002) 3.12
Helicobacter pylori attachment to gastric cells induces cytoskeletal rearrangements and tyrosine phosphorylation of host cell proteins. Proc Natl Acad Sci U S A (1996) 2.99
Cadherin-directed actin assembly: E-cadherin physically associates with the Arp2/3 complex to direct actin assembly in nascent adhesive contacts. Curr Biol (2002) 2.74
Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins. Nat Cell Biol (2002) 1.89
Molecular physiology and pathophysiology of tight junctions. I. Biogenesis of tight junctions and epithelial polarity. Am J Physiol Gastrointest Liver Physiol (2000) 1.45
Identification of CDH1 germline missense mutations associated with functional inactivation of the E-cadherin protein in young gastric cancer probands. Hum Mol Genet (2003) 1.42
IQGAP1 and calmodulin modulate E-cadherin function. J Biol Chem (1999) 1.41
Structural basis of the Ca(2+)-dependent association between S100C (S100A11) and its target, the N-terminal part of annexin I. Structure (2000) 1.34
Molecular physiology and pathophysiology of tight junctions V. assault of the tight junction by enteric pathogens. Am J Physiol Gastrointest Liver Physiol (2000) 1.23
Rho family proteins and cell migration. Biochem Soc Symp (1999) 1.22
Cell-surface attachment of pedestal-forming enteropathogenic E. coli induces a clustering of raft components and a recruitment of annexin 2. J Cell Sci (2002) 1.21
Annexin II overexpression is correlated with poor prognosis in human gastric carcinoma. Anticancer Res (2001) 1.17
Local pH elevation mediated by the intrabacterial urease of Helicobacter pylori cocultured with gastric cells. J Clin Invest (2000) 1.09
The intracellular E-cadherin germline mutation V832 M lacks the ability to mediate cell-cell adhesion and to suppress invasion. Oncogene (2003) 1.08
Characteristics of Helicobacter pylori attachment to human primary antral epithelial cells. Microbes Infect (2000) 1.07
Establishment of the circumferential actin filament network is a prerequisite for localization of the cadherin-catenin complex in epithelial cells. Cell Growth Differ (1999) 1.04
Abnormal expression and function of the E-cadherin-catenin complex in gastric carcinoma cell lines. Br J Cancer (1999) 1.02
Modulating signaling events in smooth muscle: cleavage of annexin 2 abolishes its binding to lipid rafts. FASEB J (2002) 1.01
EBV-expressing AGS gastric carcinoma cell sublines present increased motility and invasiveness. Int J Cancer (2002) 1.00
Reduction in membranous expression of beta-catenin and increased cytoplasmic E-cadherin expression predict poor survival in gastric cancer. Br J Cancer (1999) 1.00
Gastric cancer cell lines as models to study human digestive functions. J Cell Biochem (2001) 0.96
Cell vacuolation induced by the VacA cytotoxin of Helicobacter pylori is regulated by the Rac1 GTPase. J Biol Chem (2000) 0.95
Complete regression of primary gastric MALT-lymphoma after double eradication Helicobacter pylori therapy: role and importance of endoscopic ultrasonography. Anticancer Res (2001) 0.92
Somatostatin, acting at receptor subtype 1, inhibits Rho activity, the assembly of actin stress fibers, and cell migration. J Biol Chem (2002) 0.89
Subtype-specific signaling mechanisms of somatostatin receptors SSTR1 and SSTR2. J Biol Chem (1994) 0.86
Autoinduction of the trefoil factor 2 (TFF2) promoter requires an upstream cis-acting element. Biochem Biophys Res Commun (2002) 0.85
S100A1 and S100B interactions with annexins. Biochim Biophys Acta (2000) 0.84
Effect of cholecystokinin and secretin on somatostatin release from cultured antral cells. Gastroenterology (1993) 0.80
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe (2008) 11.08
Gut microbiota in health and disease. Physiol Rev (2010) 7.76
Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature (2010) 6.26
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host Microbe (2007) 5.56
Dissecting virulence: systematic and functional analyses of a pathogenicity island. Proc Natl Acad Sci U S A (2004) 5.34
Molecular mechanisms of Escherichia coli pathogenicity. Nat Rev Microbiol (2010) 4.13
Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. PLoS Pathog (2010) 3.76
Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection. Infect Immun (2008) 3.68
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host Microbe (2007) 3.28
Manipulation of host-cell pathways by bacterial pathogens. Nature (2007) 2.89
Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening. EMBO J (2003) 2.87
The caspase-1 inflammasome: a pilot of innate immune responses. Cell Host Microbe (2008) 2.71
Evidence of a large novel gene pool associated with prokaryotic genomic islands. PLoS Genet (2005) 2.71
Type III secretion systems and disease. Clin Microbiol Rev (2007) 2.61
Invasive and adherent bacterial pathogens co-Opt host clathrin for infection. Cell Host Microbe (2007) 2.53
Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7. Mol Microbiol (2004) 2.51
Pathogenicity islands: a molecular toolbox for bacterial virulence. Cell Microbiol (2006) 2.44
Recent advances in understanding enteric pathogenic Escherichia coli. Clin Microbiol Rev (2013) 2.43
Shifting the balance: antibiotic effects on host-microbiota mutualism. Nat Rev Microbiol (2011) 2.43
Microbial pathogenesis and cytoskeletal function. Nature (2003) 2.38
Salmonella enterica serovar Typhimurium pathogenicity island 2 is necessary for complete virulence in a mouse model of infectious enterocolitis. Infect Immun (2005) 2.32
Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies. Infect Immun (2004) 2.32
Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice. Mol Microbiol (2003) 2.21
Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens. Nat Rev Mol Cell Biol (2003) 2.21
Structural characterization of the molecular platform for type III secretion system assembly. Nature (2005) 2.20
Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium. Infect Immun (2003) 2.17
Quorum sensing in bacterial virulence. Microbiology (2010) 2.15
Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosis. Gastroenterology (2008) 2.05
A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system. Nat Struct Mol Biol (2009) 2.02
Cellular uptake, intracellular trafficking, and cytotoxicity of nanomaterials. Small (2011) 2.00
Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication. Proc Natl Acad Sci U S A (2004) 2.00
The invasion-associated type III secretion system of Salmonella enterica serovar Typhimurium is necessary for intracellular proliferation and vacuole biogenesis in epithelial cells. Cell Microbiol (2002) 2.00
Severe FVII deficiency caused by a new point mutation combined with a previously undetected gene deletion. Br J Haematol (2005) 2.00
An anti-infective peptide that selectively modulates the innate immune response. Nat Biotechnol (2007) 1.97
Analysis of the contribution of Salmonella pathogenicity islands 1 and 2 to enteric disease progression using a novel bovine ileal loop model and a murine model of infectious enterocolitis. Infect Immun (2005) 1.88
Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice. Infect Immun (2006) 1.87
Molecular analysis as an aid to assess the public health risk of non-O157 Shiga toxin-producing Escherichia coli strains. Appl Environ Microbiol (2008) 1.84
Defining a healthy human gut microbiome: current concepts, future directions, and clinical applications. Cell Host Microbe (2012) 1.81
Expression and secretion of Salmonella pathogenicity island-2 virulence genes in response to acidification exhibit differential requirements of a functional type III secretion apparatus and SsaL. J Biol Chem (2004) 1.81
The role of the intestinal microbiota in enteric infection. J Physiol (2009) 1.80
A positive regulatory loop controls expression of the locus of enterocyte effacement-encoded regulators Ler and GrlA. J Bacteriol (2005) 1.77
Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses. J Immunol (2009) 1.77
Decreased shedding of Escherichia coli O157:H7 by cattle following vaccination with type III secreted proteins. Vaccine (2004) 1.77
Cardiac ryanodine receptors control heart rate and rhythmicity in adult mice. Cardiovasc Res (2012) 1.77
Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella. Nat Cell Biol (2002) 1.75
Human recombinant erythropoietin augments serum asymmetric dimethylarginine concentrations but does not compromise nitric oxide generation in mice. Nephrol Dial Transplant (2008) 1.75
The enemy within us: lessons from the 2011 European Escherichia coli O104:H4 outbreak. EMBO Mol Med (2012) 1.75
v-SNAREs control exocytosis of vesicles from priming to fusion. EMBO J (2005) 1.75
The Salmonella effector protein SopB protects epithelial cells from apoptosis by sustained activation of Akt. J Biol Chem (2005) 1.74
Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid. Proc Natl Acad Sci U S A (2005) 1.73
Mice lacking T and B lymphocytes develop transient colitis and crypt hyperplasia yet suffer impaired bacterial clearance during Citrobacter rodentium infection. Infect Immun (2002) 1.73
Attaching and effacing pathogen-induced tight junction disruption in vivo. Cell Microbiol (2006) 1.73
Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast. Genome Res (2002) 1.72
A role for the beta-catenin/T-cell factor signaling cascade in vascular remodeling. Circ Res (2002) 1.72
Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release. Kidney Int (2013) 1.71
Toll-like receptor 4 dependence of innate and adaptive immunity to Salmonella: importance of the Kupffer cell network. J Immunol (2004) 1.67
Salmonella type III effectors PipB and PipB2 are targeted to detergent-resistant microdomains on internal host cell membranes. Mol Microbiol (2003) 1.67
Secretin of the enteropathogenic Escherichia coli type III secretion system requires components of the type III apparatus for assembly and localization. Infect Immun (2003) 1.67
Effect of antibiotic treatment on the intestinal metabolome. Antimicrob Agents Chemother (2011) 1.64
SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. J Cell Biol (2008) 1.64
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function. PLoS Pathog (2009) 1.61
Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets. Cell Transplant (2009) 1.60
Translocated intimin receptor and its chaperone interact with ATPase of the type III secretion apparatus of enteropathogenic Escherichia coli. J Bacteriol (2003) 1.58
SifA, a type III secreted effector of Salmonella typhimurium, directs Salmonella-induced filament (Sif) formation along microtubules. Traffic (2002) 1.57
The intestinal microbiota plays a role in Salmonella-induced colitis independent of pathogen colonization. PLoS One (2011) 1.57
Disruption of the Salmonella-containing vacuole leads to increased replication of Salmonella enterica serovar typhimurium in the cytosol of epithelial cells. Infect Immun (2002) 1.56
Gap junction hemichannels contribute to the generation of diarrhoea during infectious enteric disease. Gut (2009) 1.56
Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. Mol Biol Cell (2004) 1.56
DNA microarray profiling to identify angiotensin-responsive genes in vascular smooth muscle cells: potential mediators of vascular disease. Circ Res (2003) 1.55
Bacterial genetic determinants of non-O157 STEC outbreaks and hemolytic-uremic syndrome after infection. J Infect Dis (2006) 1.52
Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogens. Infect Immun (2005) 1.51
Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells. Am J Pathol (2004) 1.51
Salmonella effectors within a single pathogenicity island are differentially expressed and translocated by separate type III secretion systems. Mol Microbiol (2002) 1.51
Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine. PLoS Pathog (2005) 1.50
Crossing the line: selection and evolution of virulence traits. PLoS Pathog (2006) 1.49
Caveolin-3 is adjacent to a group of extradyadic ryanodine receptors. Biophys J (2005) 1.49
Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter. Mol Cell Biol (2008) 1.48
Tight junctions as targets of infectious agents. Biochim Biophys Acta (2008) 1.47
The Salmonella enterica serovar typhimurium divalent cation transport systems MntH and SitABCD are essential for virulence in an Nramp1G169 murine typhoid model. Infect Immun (2004) 1.46
Pathogenesis of enteric Salmonella infections. Curr Opin Gastroenterol (2008) 1.46
Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS. Nature (2008) 1.45
Molecular mechanisms of Salmonella virulence and host resistance. Curr Top Microbiol Immunol (2009) 1.45
Rhinovirus disrupts the barrier function of polarized airway epithelial cells. Am J Respir Crit Care Med (2008) 1.43
Cubilin and amnionless mediate protein reabsorption in Drosophila nephrocytes. J Am Soc Nephrol (2012) 1.42
The role of the immune system in governing host-microbe interactions in the intestine. Nat Immunol (2013) 1.41
Structural analysis of a prototypical ATPase from the type III secretion system. Nat Struct Mol Biol (2007) 1.40
Gastric mucosal recognition of Helicobacter pylori is independent of Toll-like receptor 4. J Infect Dis (2003) 1.39
Host-pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes. Proc Natl Acad Sci U S A (2002) 1.39
Salmonella infection of gallbladder epithelial cells drives local inflammation and injury in a model of acute typhoid fever. J Infect Dis (2009) 1.39
Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenance. Blood (2007) 1.39
Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells. Cancer Res (2008) 1.39
Transcriptional inhibitor of virulence factors in enteropathogenic Escherichia coli. Antimicrob Agents Chemother (2005) 1.38
Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. Mol Biol Cell (2005) 1.37
Structural characterization of a type III secretion system filament protein in complex with its chaperone. Nat Struct Mol Biol (2004) 1.37
Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages. J Immunol (2010) 1.37
Enhanced anti-tumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxy PEG-PLGA copolymer nanoparticles. Biomaterials (2011) 1.36
Citrobacter rodentium infection causes both mitochondrial dysfunction and intestinal epithelial barrier disruption in vivo: role of mitochondrial associated protein (Map). Cell Microbiol (2006) 1.35