Helicobacter pylori and gastric cancer: factors that modulate disease risk.

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Published in Clin Microbiol Rev on October 01, 2010

Authors

Lydia E Wroblewski1, Richard M Peek, Keith T Wilson

Author Affiliations

1: Division of Gastroenterology, Vanderbilt University School of Medicine, 2215 Garland Ave., 1030C MRB IV, Nashville, TN 37232-2279, USA. Lydia.Wroblewski@vanderbilt.edu

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The hyaluronic acid receptor CD44 coordinates normal and metaplastic gastric epithelial progenitor cell proliferation. J Biol Chem (2013) 1.14

The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis. J Biol Chem (2010) 1.14

Evidence for repatterning of the gastric fundic epithelium associated with Ménétrier's disease and TGFalpha overexpression. Gastroenterology (2005) 1.14

Tumor suppressor function of the plasma glutathione peroxidase gpx3 in colitis-associated carcinoma. Cancer Res (2012) 1.13

STAT6 activation in ulcerative colitis: a new target for prevention of IL-13-induced colon epithelial cell dysfunction. Inflamm Bowel Dis (2011) 1.13

Prospective study of Helicobacter pylori biomarkers for gastric cancer risk among Chinese men. Cancer Epidemiol Biomarkers Prev (2012) 1.13

Berberine promotes recovery of colitis and inhibits inflammatory responses in colonic macrophages and epithelial cells in DSS-treated mice. Am J Physiol Gastrointest Liver Physiol (2011) 1.12

Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans. Gastroenterology (2012) 1.12

Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor. PLoS One (2012) 1.12

Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia. Gastroenterology (2008) 1.11

Helicobacter pylori in gastric carcinogenesis: mechanisms. Gastroenterol Clin North Am (2013) 1.11

Pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses. Proc Natl Acad Sci U S A (2012) 1.11

Helicobacter pylori induces ERK-dependent formation of a phospho-c-Fos c-Jun activator protein-1 complex that causes apoptosis in macrophages. J Biol Chem (2010) 1.08

β-Catenin and p120 mediate PPARδ-dependent proliferation induced by Helicobacter pylori in human and rodent epithelia. Gastroenterology (2011) 1.08

Helicobacter pylori represses proton pump expression and inhibits acid secretion in human gastric mucosa. Gut (2010) 1.08

L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis. PLoS One (2012) 1.08

The apolipoprotein E-mimetic peptide COG112 inhibits the inflammatory response to Citrobacter rodentium in colonic epithelial cells by preventing NF-kappaB activation. J Biol Chem (2008) 1.08

Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells. Gut (2011) 1.08

Mouse strain susceptibility to trypanosome infection: an arginase-dependent effect. J Immunol (2004) 1.07

Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis. PLoS One (2013) 1.07

Regulation of gastric B cell recruitment is dependent on IL-17 receptor A signaling in a model of chronic bacterial infection. J Immunol (2009) 1.04

Expression of the Helicobacter pylori adhesin SabA is controlled via phase variation and the ArsRS signal transduction system. Microbiology (2008) 1.04

MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model. Cancer Res (2011) 1.02

Immune evasion by Helicobacter pylori is mediated by induction of macrophage arginase II. J Immunol (2011) 1.02

Host cell responses to genotypically similar Helicobacter pylori isolates from United States and Japan. Clin Diagn Lab Immunol (2002) 1.02

Subproteomes of soluble and structure-bound Helicobacter pylori proteins analyzed by two-dimensional gel electrophoresis and mass spectrometry. Proteomics (2005) 1.02

Helicobacter pylori genotyping and sequencing using paraffin-embedded biopsies from residents of colombian areas with contrasting gastric cancer risks. Helicobacter (2008) 1.01

Delineation of a carcinogenic Helicobacter pylori proteome. Mol Cell Proteomics (2009) 1.00

A Helicobacter pylori restriction endonuclease-replacing gene, hrgA, is associated with gastric cancer in Asian strains. Cancer Res (2002) 0.98

Low multiplicity of infection of Helicobacter pylori suppresses apoptosis of B lymphocytes. Cancer Res (2006) 0.98

Novel 180- and 480-base-pair insertions in African and African-American strains of Helicobacter pylori. J Clin Microbiol (2004) 0.98

Identification of a signaling cascade for interleukin-8 production by Helicobacter pylori in human gastric epithelial cells. Biochem Pharmacol (2002) 0.98

Analysis of Helicobacter pylori cagA promoter elements required for salt-induced upregulation of CagA expression. Infect Immun (2012) 0.97

STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines. J Immunol (2013) 0.96